Scienmag

FEBRUARY 22, 2021

HSE University researchers have become the first in the world to discover genetic predisposition to severe COVID-19. Credit: S.Nersisyan et al. The results of the study were published in the journal Frontiers in Immunology. T-cell immunity is one of the key mechanisms used by the human body to fight virus infections.

Genetics 52

Genetics Research Allergies 52

Medical Xpress

FEBRUARY 6, 2023

People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an article about this in Nature Communications.

Allergies 75

Allergies Gene Development Research 75

Scienmag

MARCH 4, 2021

COVID genetic mystery, power outage costs, Alzheimer pathology, optical antennas Credit: National Institute of Allergy and Infectious Diseases-Rocky Mountain Laboratories, NIH Solving a Genetic Mystery at the Heart of the COVID-19 Pandemic As the COVID-19 pandemic enters its second year, scientists are still working to understand how the new strain (..)

Allergies 55

Allergies Genetics Scientist Medicine 55

Scienmag

AUGUST 14, 2020

Finding could lead to genetic tests that identify infants at risk for the disease Credit: NIAID WHAT: New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development (..)

Genetics 52

Genetics Scientist Gene Development 52

Scienmag

AUGUST 14, 2020

Discovery could lead to new screening tests and potential treatments Credit: Cincinnati Children’s Two common variants in the KIF3A gene increase the risk of young children having a dysfunctional skin barrier and developing the skin condition atopic dermatitis.

Allergies 97

Allergies Gene Development Dermatology 97

Scienmag

DECEMBER 3, 2020

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

Genetic Engineering 40

Genetic Engineering Engineer Genetics Bacteria 40

Scienmag

OCTOBER 29, 2020

USF Health-led TEDDY analysis focuses on development of multiple distinct autoantibodies targeting insulin-producing cells, from initial autoimmunity to symptomatic type 1 diabetes Credit: Courtesy of USF Health TAMPA, Fla.

Genetics 92

Genetics Insulin Development Clinical Trials 92

Scienmag

SEPTEMBER 4, 2020

Anticholinergic medications are used for many conditions but might also accelerate cognitive decline, especially in older persons with biological or genetic risk factors A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad array of conditions, from allergies (..)

Allergies 41

Allergies Drugs Genetics Scientist 41

XTalks

MARCH 18, 2024

By genetically editing microorganisms, scientists can now manipulate the metabolic pathways to produce foods with desirable properties. The precision fermentation study highlights how genetically engineered microorganisms can inhibit the growth of foodborne pathogens.

Genetic Engineering 52

Genetic Engineering Genetics Production Protein 52

The Pharma Data

JULY 11, 2021

3 These data are being presented at the 2021 European Academy of Allergy and Clinical Immunology (EAACI) Hybrid Congress in Krakow, Poland and Madrid, Spain. In the first analysis, the mean (min, max) reduction in the attack rate compared to baseline observed in the study population (N=212) was of 87.4 percent and a median reduction of 98.2

Allergies 52

Allergies Recombinant DNA Technology Antibody Production 52

The Pharma Data

JANUARY 11, 2021

While the blueprint is a genetic code, it never enters the nucleus of the cells. People with non-vaccine related allergies — such as food allergies, pet allergies, seasonal allergies — can be safely vaccinated, according to the U.S. “That means it never converts into DNA,” Dr. M.

Vaccination 52

Vaccination Vaccine Allergies Protein 52

Scienmag

DECEMBER 13, 2020

In this type of therapy, T cells, a type of white blood cell, are collected from a patient’s blood and subjected to genetic engineering to produce T cells carrying a synthetic molecule termed chimeric antigen receptor (CAR) […].

Genetic Engineering 95

Genetic Engineering Engineer Genetics Allergies 95

Scienmag

APRIL 28, 2021

New NIH-funded grant supports studying phages as a preventive, therapeutic approach The National Institute of Allergy and Infectious Diseases, NIAID, part of the National Institutes of Health, NIH, has awarded $2.5 Woman, Dr.

Research 62

Research Allergies Genetics Medicine 62

FDA Law Blog

DECEMBER 8, 2022

labeling of major food allergens in bulk foods, dietary supplements, protein-free ingredients, and foods produced through genetic engineering); and. labeling of major food allergens in bulk foods, dietary supplements, protein-free ingredients, and foods produced through genetic engineering); and. Other technical labeling matters.

Genetic Engineering 59

Genetic Engineering Containment Cosmetics Protein 59

XTalks

SEPTEMBER 8, 2020

The funding for the trial is being supported by the National Institute of Allergy and Infectious Diseases (NIAID) and the Biomedical Advanced Research and Development Authority (BARDA). The genetic material contains SARS-CoV-2 spike protein.

Manufacturing 83

Manufacturing Vaccination Vaccine Allergies 83

Scienmag

FEBRUARY 19, 2021

Anaylsis shows different genetic risk landscape for IBD In African Americans, the genetic risk landscape for inflammatory bowel disease (IBD) is very different from that of people with European ancestry, according to results of the first whole-genome study of IBD in African Americans.

Genome 50

Genome Genomics Genetics Clinical Research 50

XTalks

JULY 26, 2021

Those who seek shorter ingredient lists and cleaner labels may object to plant-based meat due to the many additives and genetically modified proteins that tend to be crucial components of its formulation. For example, the Allergen Bureau indicated a possible connection between pea protein and peanut allergies. FDA Regulation.

Protein 98

Protein Contamination Allergies Bacteria 98

Scienmag

JANUARY 8, 2021

Credit: University of Leeds Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus ‘package up’ their genetic code, allowing them to infect cells.

Packaging 94

Packaging Packaging Genetics Research 94

Scienmag

FEBRUARY 1, 2021

According to a study published in Frontiers in Immunology, the reason is their genetic heterogeneity and lack of proportional representation in the Brazilian bone marrow bank Credit: Diogo Meyer A paper by a multidisciplinary team of scientists affiliated with various Brazilian institutions, including the University of São Paulo (USP) and the National (..)

Genetics 65

Genetics Scientist Allergies Gene 65

XTalks

APRIL 21, 2023

Therefore, montelukast has been used to treat asthma and allergies for over two decades now. While the root causes of asthma are not yet fully understood, a combination of genetic and environmental factors, such as allergies, air pollution, obesity, smoking, viral infections and stress, are believed to contribute to its development.

Life Science 98

Life Science Allergies Drugs FDA Approval 98

Scienmag

JUNE 22, 2021

A new study published in Genetic Epidemiology has examined the genetic code of SARS-CoV-2 viruses that have infected patients, looking for links between different mutations and patient deaths. Viral mutations during the COVID-19 pandemic could cause the SARS-CoV-2 virus to become more dangerous.

Genetics 40

Genetics Genome Genomics Research 40

Scienmag

NOVEMBER 20, 2020

— A genetic modification in the ‘coat’ of a brain infection-causing virus may allow it to escape antibodies, according to Penn State College of Medicine researchers. HERSHEY, Pa. They say testing people for this and other viral mutations may help identify patients at risk for developing a fatal brain disease.

Antibody 71

Antibody Genetics Medicine Development 71

Scienmag

JUNE 27, 2021

A new vaccine to protect against deadly cholera has been made by grinding up genetically modified grains of rice. Study points towards role of gut microbiome in vaccine effectiveness Credit: Image by Dr. Hiroshi Kiyono, CC BY 4.0 The first human trial has shown no obvious side effects and a good immune response.

Vaccination 72

Vaccination Vaccine Immune Response Trials 72

Scienmag

FEBRUARY 11, 2021

That is according to the largest genetic study to date on patients with Addison’s disease. Credit: Karolinska Institutet Variants of nine genes increase the risk of developing Addison’s disease, a rare disease in which the immune system attacks the adrenal glands. The findings help increase knowledge about what causes the disease.

Gene 72

Gene Genetics Development Allergies 72

Scienmag

NOVEMBER 25, 2020

First and corresponding author Dr Lucy van Dorp (UCL Genetics […]. The analysis of virus genomes from over 46,000 people with COVID-19 from 99 countries is published today in Nature Communications.

Genome 58

Genome Genomics Genetics Research 58

Scienmag

DECEMBER 21, 2020

Researchers baffled by an infant’s rare encephalitis case unusual in children found unheard-of mutations and a new way to examine the ‘immunity gene’ Credit: Satoshi Okada An infant’s odd case of rare encephalitis not typically found in children led researchers to discover never before seen genetic mutations and a more accurate (..)

Gene 52

Gene Genetics Research Allergies 52

pharmaphorum

SEPTEMBER 1, 2020

The US trial is funded by the US government agency Biomedical Advanced Development Authority (BARDA), and the National Institute of Allergy and Infectious Diseases, which as part of the National Institutes of Health is funded by federal grants. Feature image courtesy of Rocky Mountain Laboratories/NIH.

Vaccination 69

Vaccination Vaccine Trials Immune Response 69

Scienmag

OCTOBER 22, 2020

Cord blood is currently used to treat more than 80 life-threatening conditions, ranging from cancer and immune deficiency to metabolic and genetic disorders. Credit: © 2020 KAUST; Heno Hwang A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants.

Genetics 69

Genetics Allergies Engineer Medicine 69

Scienmag

SEPTEMBER 1, 2020

Genetic analysis of sequences from more than 27,000 individuals infected with the coronavirus that causes COVID-19 reveals that the virus has mutated minimally since December 2019, suggesting one vaccine would be sufficient to combat global infections.

Genetic Analysis 70

Genetic Analysis Vaccination Vaccine Genetics 70

pharmaphorum

FEBRUARY 16, 2022

She received a cord blood transplant to treat the AML, receiving stem cells carrying a genetic mutation (CCR?5/?32) The case study described at the Conference on Retroviruses and Opportunistic Infections (CROI) this week involved a mixed-race woman who had been on antiretroviral therapy (ART) for four years before being diagnosed with AML.

Gene Editing 69

Gene Editing Research Gene Genetics 69

Olympian Clinical Research

AUGUST 19, 2022

The most common type of psoriasis is plaque psoriasis, which may be passed down genetically. Pediatric eczema is thought to be caused by genetic and environmental factors. About 30% of children with eczema have a food allergy, and many children may develop asthma or hay fever. Thickened, pitted, or ridged nails.

Clinical Research 52

Clinical Research Allergies Doctors Doctor 52

The Pharma Data

DECEMBER 17, 2020

But Forbes, an assistant professor of pediatrics, immunology, allergy and rheumatology at Baylor College of Medicine in Houston, said the patient’s diabetes appears to have been reversed. This patient had a genetic mutation that ruxolitinib is known to work on. It’s in a class of medications known as JAK inhibitors.

Insulin 52

Insulin Genetics Doctors Doctor 52

Scienmag

DECEMBER 21, 2020

LJI scientists track down control elements that govern gene expression from a distance Credit: Alex Fung LA JOLLA–The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease. “The difference is within us,” says Vivek Chandra, Ph.D.,

Gene Expression 52

Gene Expression Gene Genetics Scientist 52

Olympian Clinical Research

DECEMBER 22, 2021

Genetics or family history: people with family members who suffer from migraines are more likely to experience migraines. . Allergies: due to a rise of inflammation in the body, allergies can trigger migraines. However, there are certain triggers that tend to provoke migraines, including: .

Allergies 52

Allergies Clinical Research Clinical Trials Clinical Trials 52

Scienmag

NOVEMBER 6, 2020

New study demonstrates candidate’s potential to generate antibodies, limit viral shedding Credit: Craig Chandler, University of Nebraska-Lincoln A genetically edited form of a herpes simplex virus — rewired to keep it from taking refuge in the nervous system and eluding an immune response — has outperformed a leading vaccine candidate (..)

Vaccination 49

Vaccination Vaccine Immune Response Genetics 49

Scienmag

JUNE 22, 2021

MicroRNAs are genetic molecules that prevent the production of particular proteins by binding to and destroying messenger RNAs that code for those proteins. Investigators found that the […].

Protein 42

Protein Genetics Medicine Production 42

Scienmag

JANUARY 13, 2021

The finding from a genetic analysis of tumors treated with Duke’s poliovirus therapy suggests a predictive biomarker for survival DURHAM, N.C. – Glioblastoma brain tumors are especially perplexing.

Genetic Analysis 43

Genetic Analysis Genetics Allergies Medicine 43