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Common class of drugs linked to increased risk of Alzheimer’s disease

Scienmag

Anticholinergic medications are used for many conditions but might also accelerate cognitive decline, especially in older persons with biological or genetic risk factors A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad array of conditions, from allergies (..)

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Chronic attack on the aging nervous system

Scienmag

Credit: Image: Janos Groh / Reprinted by permission from Springer Nature Aging is the biggest risk factor for perturbation of the nervous system, even in the absence of distinct disease or trauma.

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With age, insufficient tryptophan alters gut microbiota, increases inflammation

Scienmag

Credit: Augusta University With age, a diet lacking in the essential amino acid tryptophan — which has a key role in our mood, energy level and immune response — makes the gut microbiome less protective and increases inflammation body-wide, investigators report.

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Analysis reveals high burden of musculoskeletal disorders across the globe

Scienmag

Musculoskeletal disorders–which affect muscles, tendons, ligaments, bones, and joints–can severely affect individuals’ physical and mental health, and they’re especially prevalent among aging adults.

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Existing heart drugs may help cancer patients respond better to PD(L)1 immunotherapy

Scienmag

Researchers have found that a class of commonly-used heart drugs may also improve patients’ responses to anti-cancer immunotherapies called PD(L)1 inhibitors, according to preliminary findings to be presented at the 32th EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics, which is taking place online.

Drugs 73
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Many older adults hospitalized with the flu face persistent functional decline

Scienmag

In a study of older adults admitted to the hospital with influenza and other acute respiratory illnesses during the 2011-2012 flu season, functional decline was common–and for some, this decline was persistent and catastrophic. The findings are published in the Journal of the American Geriatrics Society.

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Does air pollution affect mental health later in life?

Scienmag

In a study of women aged 80 years and older, living in locations with higher exposures to air pollution was associated with increased depressive symptoms. The findings are published in the Journal of the American Geriatrics Society.