Scienmag

MARCH 8, 2021

Bacteria integrate genetic material from other bacterial strains more easily than previously thought, which can lead to improved fitness and accelerated evolution. The team analysed genome transfer between bacteria of different lineages. This is shown in a recent study by biophysicists at the University of Cologne.

Bacteria 75

Bacteria Genome Genomics Genetics 75

XTalks

JULY 31, 2020

A study published in Nature on July 30, 2020 states that good bacteria living in our gut can do much more than just help digest food and boost our immune system. According to studies conducted by researchers at Cincinnati Children’s Hospital, the bacteria can help heal damaged intestinal tissues.

Bacteria 98

Bacteria Genetic Engineering Engineer Research 98

Scienmag

DECEMBER 9, 2020

A new genetic approach can accelerate the study of phage-microbe interactions with implications for health, agriculture, and climate Credit: Wikimedia Commons Scientists are continually searching for new and improved ways to deal with bacteria, be it to eliminate disease-causing strains or to modify potentially beneficial strains.

Bacteria 52

Bacteria Genetic Engineering Genetics Engineer 52

Scienmag

SEPTEMBER 8, 2020

Credit: Avalos Lab/Princeton University Researchers at Princeton University have created a new and improved way to more precisely control genetically engineered bacteria: by simply switching the lights on and off. Working in E.

Bacteria 56

Bacteria Genetic Engineering Engineer Genetics 56

Scienmag

JANUARY 8, 2021

Now research reveals that bacteria too have internal clocks that align with the 24-hour cycle of life on Earth. Credit: Professor Ákos Kovács, Technical University of Denmark Humans have them, so do other animals and plants.

Bacteria 66

Bacteria Drug Delivery Research Drugs 66

Scienmag

NOVEMBER 24, 2020

Credit: RIKEN A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in experimentally evolving the common bacteria Escherichia coli under pressure from a large number of individual antibiotics. In doing so, they were able to identify the mechanisms and constraints underlying evolved drug resistance.

Bacteria 82

Bacteria Drugs Research Genetics 82

Scienmag

APRIL 14, 2021

Credit: Surajit Chatterjee To better understand how RNA in bacteria gives rise to protein–and along the way, target these processes in the design of new antibiotics–researchers are turning their attention to the unique way this process happens in bacteria.

RNA 82

RNA Bacteria Protein Research 82

Scienmag

DECEMBER 18, 2020

Bacteria often show very strong biogeography – some bacteria are abundant in specific locations while absent from others – leading to major questions when applying microbiology to therapeutics or probiotics: how […].

Bacteria 52

Bacteria Genome Genomics Research 52

Scienmag

MAY 26, 2021

Researchers turn now to see how COVID-19 pandemic affected microbiome in each city Each city has its own unique microbiome, a “fingerprint” of viruses and bacteria that uniquely identify it, according to a new study from an international consortium of researchers that included a team from the University of Maryland School of Medicine (UMSOM). (..)

Bacteria 75

Bacteria Medicine Research Genetics 75

Drug Discovery World

MARCH 21, 2023

In a step forward for genetic engineering and synthetic biology, US researchers have modified E coli bacteria to be immune to infection by all natural viruses tested so far. The team used two safeguard methods to prevent the bacteria and their modified genes from escaping into the wild.

Engineer 52

Engineer Genetic Engineering Scientist Bacteria 52

BioSpace

DECEMBER 6, 2021

Proof of concept for the Genetically Engineered Microbial Medicines (GEMM) platform came in a recent first-in-human, Phase I trial.

Genetic Engineering 93

Genetic Engineering Bacteria Engineer Genetics 93

Scienmag

MAY 7, 2021

Study describes new mechanism for terminating transcription of DNA into RNA in bacteria Credit: Babitzke Laboratory and Dani Zemba, Penn State The protein, known as NusG, pauses the transcription machinery at specific DNA sequences to facilitate what is called “intrinsic termination” and prevent unwanted transcription that could disrupt (..)

Genetics 53

Genetics DNA Bacteria RNA 53

Scienmag

MARCH 8, 2021

Credit: Shutterstock Researchers have identified a critical mechanism that allows deadly bacteria to gain resistance to antibiotics. The findings offer a potential new drug target in the search for effective new antibiotics as we face the growing threat of antimicrobial resistance (AMR) and infections caused by bacterial pathogens.

Bacteria 52

Bacteria Research Drugs Genetics 52

Pharmaceutical Technology

DECEMBER 14, 2022

Bacteria naturally develop resistance to antibiotics over time, through genetic mutation, horizontal gene transfer between bacteria, or because of selective pressure. Virus versus bacteria. Phages are viruses of bacteria. Secondly, the relationships between phages and bacteria are very specific.

Bacteria 130

Bacteria DNA Clinical Trials Clinical Trials 130

Scienmag

DECEMBER 3, 2020

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

Genetic Engineering 40

Genetic Engineering Engineer Genetics Bacteria 40

Scienmag

JANUARY 20, 2021

Credit: Jan Zrimec/Chalmers University of Technology Pathogenic bacteria in humans are developing resistance to antibiotics much faster than expected. Now, computational research at Chalmers University of Technology, Sweden, shows that one reason could be significant genetic transfer between bacteria in our ecosystems and to humans.

Bacteria 97

Bacteria Genetics Development Research 97

Scienmag

MARCH 2, 2021

Kim New research suggests that the ability of green algae to eat bacteria is likely much more widespread than previously thought, a finding that could be crucial to environmental and climate science. New study points to potential widespread phagocytosis among green algae, suggests improved methodology in environmental microbiology Credit: N.

Bacteria 55

Bacteria Research Genetics 55

Scienmag

MAY 18, 2021

Scientists link genetic makeup of bacteria in the human gut to several human diseases We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome.

Bacteria 74

Bacteria Genetics Scientist Cardiology 74

STAT News

NOVEMBER 14, 2022

In this video, we chat with health policy and drug pricing researcher Hussain Lalani; Julia Joung, a molecular biologist developing genetic screening technologies; and Avinash Manjula Basavanna, who researches engineered living materials and has developed a printable ink made from bacteria.

Bacteria 96

Bacteria Engineer Genetics Research 96

Scienmag

FEBRUARY 23, 2021

Bacterial toxins that cause mutations in surviving cells profoundly shape bacterial diversity and could contribute to antibiotic resistance A toxin produced by bacteria as a defence mechanism causes mutations in target bacteria that could help them survive, according to a study published today in eLife.

Genetics 40

Genetics Bacteria Medicine 40

Medical Xpress

FEBRUARY 10, 2023

Cancer is often seen as a disease that arises from genetic mutations causing cells to divide uncontrollably and invade other parts of the body. Immune cells spread from lymph nodes to sites of infection to attack the invading bacteria. But the spread of cells away from their origins is actually a normal process in some cases.

Bacteria 61

Bacteria Genetics Development 61

Camargo

JULY 27, 2021

The technology of gene therapy is possible due to extensive DNA research and our resulting understanding of many diseases on the genetic level, and it encompasses several mechanisms such as introducing new genes (gene addition) and inactivating or replacing mutated genes (gene editing). Formulation Considerations.

Gene Therapy 238

Gene Therapy Gene Gene Editing Genetics 238

Drug Discovery World

JULY 17, 2023

Paul Denslow , CEO, Intus Bio, discusses how a new approach to tracking gut bacteria can revolutionse our understanding of the microbiome and bring about new discoveries for therapeutics. It’s a long-held doctrine that there’s no effective method to track the microbiome during drug research and development.

Bacteria 52

Bacteria Drugs Gene Immune Response 52

Scienmag

MARCH 2, 2021

Process paves a road to safe, ethical, and fast drug manufacturing Credit: Rensselaer Polytechnic Institute TROY, N.Y. — Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.

Bacteria 86

Bacteria Bacterium Drugs Scientist 86

Drug Discovery World

JANUARY 23, 2024

For example, enzymes sourced from bacteria living around hydrothermal vents have been used to support the polymerase chain reaction, the test used for Covid-19 detection. The ocean’s microbes represent the earliest lifeforms on Earth, making them important to study, not only for the evolution of life, but also for biotechnology.

DNA 103

DNA Drugs Gene Scientist 103

Medical Xpress

JANUARY 4, 2023

Like humans, bacteria and archaea can be attacked by viruses. Bacterial defenses, such as CRISPR-Cas systems, have diverse proteins and functions that help bacteria protect themselves against foreign invaders. These microorganisms have developed their own immune defense strategies against their pathogens.

Bacteria 71

Bacteria Gene Research Protein 71

Medical Xpress

NOVEMBER 16, 2022

The spread of antibiotic resistant bacteria in hospitals could be greatly reduced thanks to research by The University of Queensland and Queensland Health.

Genome 92

Genome Genomics Bacteria Research 92

Scienmag

MAY 10, 2021

Researchers reconstruct the oral microbiomes of Neanderthals, primates, and humans, including the oldest oral microbiome ever sequenced from a 100,000-year-old Neanderthal, and discover unexpected clues about human evolution and health Credit: Werner Siemens Foundation, Felix Wey Living in and on our bodies are trillions of microbial cells belonging (..)

Bacteria 52

Bacteria Research Genetics 52

STAT News

MARCH 29, 2023

Fortunately, there were already multiple strains of bacteria that infected and killed these insects. Why not learn from the best? Continue to STAT+ to read the full story…

Protein 105

Protein Bacteria Research Genetics 105

pharmaphorum

OCTOBER 7, 2020

Originally discovered in bacteria as a defense mechanism against pathogens, CRISP/Cas9 has made it possible to make exquisitely detailed and precise alterations to DNA sequences on demand, and as a tool for molecular biology has already transformed research into diseases and drug discovery. What started as a curiosity?driven,

Gene Editing 105

Gene Editing Bacteria DNA Gene 105

Drug Discovery World

NOVEMBER 17, 2022

The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape. The Rockefeller University 2 recently reported the development of a synthetic antibiotic that could potentially work against drug-resistant bacteria.

Bacteria 52

Bacteria Engineer Gene Genetics 52

Medical Xpress

DECEMBER 7, 2022

Researchers aiming to predict which staph-infection patients might develop a related kidney disease have found a high frequency of gene mutations in the infecting bacteria of affected patients, which suggests these variants may play a role in the body's initiation of the renal damage.

Gene 72

Gene Bacteria Development Research 72

Scienmag

JUNE 24, 2021

NIH scientists discover that bacteria may drive activity of many hallmark aging genes in flies Credit: Courtesy of the Giniger lab NIH/NINDS.

Scientist 72

Scientist Gene Bacteria Research 72

The Pharma Data

JUNE 14, 2023

But the bacteria can sometimes change their behavior and enter the bloodstream, causing chronic localized infections to become acute and potentially fatal. According to Whiteley and Cao, bacteria, like animals, are versatile and behave differently depending on their environment.

RNA 40

RNA Regulation Scientist Bacteria 40

Pharmaceutical Technology

FEBRUARY 15, 2023

The key component in all vaccines is one or more active ingredients made from viruses or bacteria, also called antigens, which generates an immune response. The active component of the Pfizer-BioNTech vaccine tozinameran, contains the genetic code for the coronavirus spike protein, inside a lipid (fat) capsule.

Vaccination 130

Vaccination Vaccine Containment Immune Response 130

The Pharma Data

NOVEMBER 12, 2020

12, 2020 — Lung cancer patients who harbor certain bacteria in the airways may have a poorer prognosis, a new study finds, adding to evidence that the body’s “microbiome” may play a role in cancer patients’ outlook. None of that proves the bacteria, themselves, were to blame, Segal said. THURSDAY, Nov.

Bacteria 52

Bacteria Immune Response Research Doctors 52

Drug Discovery World

JULY 12, 2022

Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe. MRSA is becoming more common among the pathogenic bacteria that cause lung infections in cystic fibrosis patients. It’s thought that around 25% of people with the disease are infected with MRSA.

Bacteria 52

Bacteria Genetic Disease Genetics Clinical Development 52