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Symvivo’s Oral COVID-19 Vaccine Enters Clinical Trials

XTalks

DNA vaccines designed using the platform consist of a combination of an advanced gene expression plasmid (pDNA) with gene(s) of interest, and a probiotic bacterium to deliver the vaccine directly to the gut, where it binds to intestinal epithelial cells.

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Scientists discover small RNA that regulates bacterial infection

The Pharma Data

Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with cystic fibrosis.

RNA 40
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Anti-tumor agent from the intestine

The Pharma Data

On the other hand, they can inhibit specific enzymes that regulate the accessibility to the genetic material and thus the gene expression in the T cells. On the one hand, they can boost the metabolism of T cells by inducing central regulators of energy metabolism. In doing so, they induce epigenetic changes.

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2020 Year in Review: COVID-19, CRISPR and Immunotherapies Define the Year for the Life Sciences

XTalks

When a virus infects bacteria (these viruses are called bacteriophages), parts of its genetic material can get incorporated into the genome of the bacterium as sequences called clustered regularly interspaced short palindromic repeats (CRISPR).