Scienmag

OCTOBER 22, 2020

When animals eat, prey DNA travels all the way through animal digestive tracts and comes out again. Credit: Illustration by Amy Koehler Poop is full of secrets. For scientists, digging into feces provides insights into animal diets and is particularly useful for understanding nocturnal or rare species.

DNA 54

DNA Containment Scientist Bioinformatics 54

Drug Discovery World

FEBRUARY 8, 2024

Andrea O’Hara, PhD, Strategic Technical Specialist, Azenta Life Sciences led the presentation and was joined by Elizabeth Louie, PhD, Supervisor, Technical Applications, Xiangying Mao, PhD, Team Lead, Bioinformatics, and Crystal Richardson, PhD, Business Partnership Manager – all Azenta Life Sciences – for the questions section.

Gene Therapy 59

Gene Therapy Gene Bioinformatics Life Science 59

Scienmag

JANUARY 12, 2021

Researchers have found a simple way to eliminate almost all sequencing errors produced by a widely used portable DNA sequencer, potentially enabling scientists working outside the lab to study and track microorganisms like the SARS-CoV-2 virus more efficiently.

DNA 40

DNA Scientist Research Bioinformatics 40

Drug Discovery World

OCTOBER 3, 2023

Andrea O’Hara, PhD, Strategic Technical Specialist, Azenta Life Sciences led the presentation and was joined by Elizabeth Louie, PhD, Supervisor, Technical Applications, Xiangying Mao, PhD, Team Lead, Bioinformatics, and Crystal Richardson, PhD, Business Partnership Manager – all Azenta Life Sciences – for the questions section.

Gene Therapy 52

Gene Therapy Gene Life Science Bioinformatics 52

Scienmag

MARCH 12, 2021

UMD-led research identifies age-related changes to DNA and reveals longevity-related differences between bat species Credit: G. Tschapka A new study led by University of Maryland and UCLA researchers found that DNA from tissue samples can be used to accurately predict the age of bats in the wild. Wilkinson, G. Puechmaille, M.

DNA 98

DNA Research Bioinformatics Genetics 98

Drug Discovery World

MAY 16, 2023

The company’s DNA-based platform is being developed to address manufacturing challenges associated with the production of recombinant adeno-associated virus (rAAV) vectors used to produce advanced therapy medicinal products (ATMPs).

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Production Gene Therapy Gene Bioinformatics 52

Scienmag

JULY 20, 2021

Credit: Field Museum The Xerces blue butterfly was last seen flapping its iridescent periwinkle wings in San Francisco in the early 1940s.

DNA 92

DNA Development Bioinformatics Genetics 92

Drug Discovery World

OCTOBER 20, 2023

BioCina will provide process development and GMP manufacturing for Minicircle DNA and Plasmid DNA. Anders Grøn, CEO at Clinical Microbiomics, said: “We are a company made up of scientists – Innovation is at the heart of our DNA.

Drugs 52

Drugs Antibody DNA Gene Therapy 52

Scienmag

APRIL 20, 2021

Real-world disease and parasite monitoring is often hampered by the inability of traditional approaches to easily sample broad geographical areas and large numbers of individuals. This can result in patchy data that fall short of what researchers need to anticipate and address outbreaks.

RNA 72

RNA DNA Research Bioinformatics 72

The Pharma Data

SEPTEMBER 11, 2021

By leveraging our unique ability to manufacture DNA at scale, we can construct proprietary antibody libraries precisely designed to match sequences that occur in the human body. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip.

Antibody 52

Antibody DNA Containment Manufacturing 52

XTalks

SEPTEMBER 28, 2020

The test involves isolating circulating tumor DNA in the blood and sequencing it to look for relevant gene mutations. Studies have demonstrated that the test has greater sensitivity than other currently available liquid biopsy tests for NSCLC, and can help in the selection of appropriate therapies.

Gene 105

Gene DNA Life Science Genotype 105

Scienmag

OCTOBER 7, 2020

Computational algorithms enable identification and optimization of RNA-based tools for myriad applications DNA and RNA have been compared to “instruction manuals” containing the information needed for living “machines” to operate.

RNA 69

RNA DNA Containment Bioinformatics 69

Scienmag

APRIL 8, 2021

Many tumours have a higher number of mutations due to a antiviral defence mechanism, the APOBEC system, which can accidentally damage DNA and cause mutations. Credit: IRB Barcelona In cancer, personalised medicine takes advantage of the unique genetic changes in an individual tumour to find its vulnerabilities and fight it.

Scientist 53

Scientist DNA Genetics Medicine 53

Drug Discovery World

APRIL 18, 2023

He is being recognised for illuminating research contributions to defining the links between chromosomal abnormalities and cancer, including his discovery of TMPRSS2-ETS gene fusions in prostate cancer, and for pioneering the use of pathological and bioinformatic methodologies to diagnose and track prostate cancer onset and progression.

Genetics 52

Genetics DNA Research Bioinformatics 52

XTalks

JULY 19, 2021

Phosphorus developed innovations in chemistry, bioinformatics and workflow to design a vertically integrated operating system for clinical genomics within their state-of-the-art CLIA and CAP certified clinical laboratory. We should be preventing these diseases before they happen.”.

Genetics 98

Genetics Genome Genomics Gene 98

Drug Discovery World

NOVEMBER 7, 2022

They subsequently applied additional bioinformatic approaches, using advanced computer technologies to identify genetic alterations in a patients’ DNA which may be causing disease but had been overlooked during routine testing. .

Genome 52

Genome Genomics Genetics Genetic Disease 52

Scienmag

MAY 27, 2021

Cellular proteins get their marching orders from genetic instructions encoded in DNA, whose sequences are first copied and made […].

Gene Expression 41

Gene Expression RNA DNA Protein 41

The Pharma Data

JANUARY 24, 2021

Diversigen provides consultative end-to-end solutions for sequencing, bioinformatics, and statistical analysis for the study of the microbiome of living organisms and environments. Diversigen, Inc. OraSure Technologies empowers the global community to improve health and wellness by providing access to accurate, essential information.

Research 40

Research Bioinformatics Scientist Medicine 40

The Pharma Data

NOVEMBER 23, 2020

“Environmental sensitivity and corporate responsibility have been part of our DNA since our inception,” said Martine Rothblatt , Ph.D., SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C. , Chairman and Chief Executive Officer of United Therapeutics.

Bioinformatics 40

Bioinformatics Containment DNA Branding 40

XTalks

NOVEMBER 7, 2022

Liquid biopsy tests in oncology involve isolating entities such as circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and tumor-derived exosomes. The cfDNA that originates from tumors is called circulating tumor DNA (ctDNA). Optimal methods for bioinformatic analysis are still needed. percent show less reliability).

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

Drug Discovery World

NOVEMBER 15, 2022

Rapid and accurate DNA synthesis . Conventional DNA synthesis, typically used for making sequences such as primers, employs phosphoramidite chemistry, a method that was developed in the 1980s and is still considered the gold standard for DNA synthesis. .

DNA 98

DNA Drugs Antibody Engineer 98

Drug Discovery World

JULY 11, 2023

Now, with the growth of publicly available genomics, transcriptomics, and proteomics databases, the ability to quickly carry out large-scale DNA, RNA, and protein screenings, and the availability of massive sets of de-identified patient data, the amount of high-value, analysable data has reached enormous proportions.

Big Data 40

Big Data Development Life Science Drugs 40

Drug Discovery World

JULY 26, 2023

This leap in understanding, which has been facilitated by the emergence of next generation sequencing (NGS) technologies and bioinformatics tools such as artificial intelligence (AI), has brought forward a new wave of precision medicine resources, diagnostics, and therapeutics specifically aiming to leverage the microbiome.

Medicine 52

Medicine Genome Genomics Bioinformatics 52

XTalks

DECEMBER 13, 2023

This impressive growth can be attributed to Fulgent’s distinctive chemistries and advanced proprietary bioinformatics pipeline, which have been instrumental in fueling the company’s rapid advancement in recent years. In the third quarter of 2023, the company’s revenue surged to $63.7 million, marking a significant increase from the $56.1

Genetics 111

Genetics Vaccination Vaccine DNA 111

Drug Discovery World

OCTOBER 25, 2023

However, the ligation step is biased and inefficient because the enzymes that ligate the adapters, which are DNA and RNA sequences, prefer some sRNAs that the adapters are ligated to. RA: How important are bioinformatics and data analysis in helping teams analyse sequencing data?

Bioinformatics 115

Bioinformatics Genetics RNA Drugs 115

Drug Discovery World

JULY 29, 2022

Scientists from seven research institutions including the University of Oxford and the University of Edinburgh have used pioneering bioinformatic modelling to investigate the molecular interactions of the p53 protein known to give protection against cancers.

Gene 52

Gene DNA Protein Genetics 52

Drug Discovery World

APRIL 14, 2023

He is being recognised for illuminating research contributions to defining the links between chromosomal abnormalities and cancer, including his discovery of TMPRSS2-ETS gene fusions in prostate cancer, and for pioneering the use of pathological and bioinformatic methodologies to diagnose and track prostate cancer onset and progression.

Genetics 52

Genetics Research Medicine Clinical Research 52

pharmaphorum

SEPTEMBER 14, 2020

The human genome is too long to be sequenced as one continuous string by current technology – so short-read sequencing breaks DNA into short fragments that are amplified and then sequenced to produce ‘reads’ of around 150 nucleotides in length. To address these issues, scientists and clinicians are starting to look at ‘long-read’ sequencing.

Genome 118

Genome Genomics Medicine Gene 118

Roots Analysis

AUGUST 28, 2022

Recent advances in multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, cytometry and imaging, in combination with bioinformatics and biostatistics, have been translated into several popular bioanalytical platforms, such as next-generation sequencing (NGS), single-cell analysis, flow cytometry and mass spectrometry.

Genome 52

Genome Genomics RNA Genome Project 52

Drug Discovery World

SEPTEMBER 7, 2022

Many companies have embarked on a digitalisation journey, convinced that their notebook entries, DNA and protein designs, samples used in experiments, and experimental conditions should all be tracked and stored in software. If all the work scientists do is captured in software, it ought to be easier to analyse. .

Scientist 52

Scientist Life Science Antibody Protein 52

Drug Discovery World

APRIL 14, 2023

Whilst the cause of DIPG isn’t known, the disease is characterised by specific mutations in genes coding for histone proteins – a family of basic proteins which can associate with DNA due to their positive charges. BMC Bioinformatics. These mutated proteins then reprogramme the epigenome, from which the cancer develops.

Protein 52

Protein Genome Genomics DNA 52

Drug Discovery World

NOVEMBER 30, 2023

It was presented by Xiaole Shirley Liu, PhD, CEO, GV20 Therapeutics, and titled: ‘AI-based target and antibody discovery from patient tumour profiles’. To demonstrate the utility of the company’s SYNTAX system in gene assembly, the 1.7 kb Influenza A hemagglutinin gene was used as a model system.

Antibody 59

Antibody Protein Engineer In-Vivo 59

Drug Discovery World

NOVEMBER 9, 2023

Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’. Marine Houdou, Genetic Engineering Specialist, Polyplus, on: ‘From modular DNA assembly to recombinant protein production at Polyplus’.

Engineer 52

Engineer Antibody Protein In-Vivo 52

Drug Discovery World

NOVEMBER 13, 2023

Novel/alternative ML-enabled screening technologies for higher POS Following chairperson’s remarks from M Frank Erasmus, PhD, Head, Bioinformatics, Specifica, there will be four presentations and a panel discussion.

Protein 59

Protein Antibody Engineer Scientist 59

The Pharma Data

MARCH 20, 2021

Bioinformatics in the Faculty. DNA biomarker services in an accredited environment. Vandesompele is a research. professor in Functional Cancer Genomics and Applied. of Medicine and Health Sciences (Ghent University) and. also the co-founder and CSO of. Biogazelle, an innovative bioanalytical services company offering RNA and.

Reagent 52

Reagent RNA Bioinformatics Medicine 52

The Pharma Data

JANUARY 10, 2021

I actually think neuroscience is going to heat up in 2021,” said Ben Zeskind , co-founder and CEO of Immuneering , which is using bioinformatics and computational biology to develop new drugs in this space, along with oncology and immuno-oncology. Moving on From the Amyloid Hypothesis. “I

Vaccination 52

Vaccination Vaccine Regulation Drugs 52