Medical Xpress

DECEMBER 21, 2022

Effective treatments are sparse, with botulinum toxin (Botox) injections into the affected muscles considered the first-line therapy. Dystonias are potentially disabling neurological conditions that can greatly affect quality of life.

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The Pharma Data

JULY 29, 2021

are living with spasticity across a variety of neurologic conditions — BOTOX® has demonstrated efficacy and has an established safety profile with over 10 years of clinical use in adult upper limb spasticity. Senior Vice President, Chief Scientific Officer, BOTOX ® & Neurotoxins, AbbVie. million adults in the U.S.

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The Pharma Data

JUNE 18, 2021

June 8, 2021 /PRNewswire/ — Allergan Aesthetics, an AbbVie company (NYSE: ABBV ), is changing the way BOTOX ® Cosmetic, the #1 selling neurotoxin treatment 1 , is connecting with consumers. “BOTOX ® Cosmetic is honoring and celebrating the dynamic people who use our products. IRVINE, Calif.

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Fierce Pharma

AUGUST 14, 2023

After debuting in the aesthetics market with Daxxify last year, Revance has made its way to the potentially lucrative therapeutic space. Daxxify snagged its first therapeutic indication with Monday's FDA nod to treat cervical dystonia in adults.

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Medical Xpress

APRIL 11, 2023

A team of scientists from the Universities of Sheffield, Reading and University College London (UCL) and US-based biopharmaceutical company Neuresta have created a new, elongated botulinum neurotoxin which can alleviate chronic pain without risk of paralysis or addiction.

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The Pharma Data

SEPTEMBER 10, 2021

” Researchers will present results from several studies in advanced Parkinson’s disease, including long-term, real-world data for DUODOPA ® (levodopa-carbidopa intestinal gel), as well as additional data on the long-term, real-world use of BOTOX ® (onabotulinumtoxinA) in patients with spasticity and cervical dystonia.

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BioSpace

MAY 10, 2021

AbbVie's Allergan Aesthetics' most well-known brands right now include BOTOX and CoolSculpting, among others. However, with the company's latest acquisition, another one might slide its way to the top.

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BioPharma Reporter

DECEMBER 22, 2020

Ajinomoto Bio-Pharma Services and Revance Therapeutics have announced a strategic commercial manufacturing agreement for the supply of DaxibotulinumtoxinA for Injection.

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The Pharma Data

MARCH 30, 2021

2] – The atogepant application demonstrates AbbVie’s longstanding commitment to providing multiple migraine treatment options, including BOTOX® (onabotulinumtoxinA), a preventive treatment for those with chronic migraine, and UBRELVY® (ubrogepant), an acute treatment for adults with migraine. IMPORTANT SAFETY INFORMATION.

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Pharmaceutical Technology

APRIL 18, 2023

The regulatory approval for the expanded indication was based on the data obtained from the pivotal Phase III PROGRESS trial, which assessed the efficacy, tolerability and safety of oral Qulipta 60mg once daily (QD) in adult patients with chronic migraine.

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pharmaphorum

SEPTEMBER 11, 2020

Prior to the $63 billion takeover by AbbVie, Allergan’s biggest product was botulinum toxin product Botox, best known as a wrinkle and migraine treatment, and that headed a sizeable medical aesthetics portfolio at the company which also included dermal filler products like Juvederm.

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pharmaphorum

SEPTEMBER 29, 2021

Qulipta (atogepant) is AbbVie’s second oral CGRP inhibitor after Ubrelvy (ubrogepant) – which was approved for the acute treatment of migraine attacks in 2019 – and rounds out a range that also includes the injectable Botox. Botox is prescribed for the prevention of headaches in adults diagnosed with chronic migraine.

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The Pharma Data

APRIL 7, 2021

” Researchers will present data from several studies on migraine, including new findings on atogepant, AbbVie’s investigational preventive treatment of migraine in adults who meet criteria for episodic migraine as well as results evaluating the efficacy and safety of BOTOX ® (onabotulinumtoxinA) and UBRELVY ® (ubrogepant).

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pharmaphorum

MARCH 18, 2022

Allergan fell foul of the regulations for a number of LinkedIn and Instagram posts promoting Botox (botulinum toxin type A) to the public by the chief executive of aesthetics clinic – described in his profile as an ‘Allergan mentee’, which were also liked or commented on by employees of the company.

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pharmaphorum

NOVEMBER 4, 2020

This year of course there have also been access issues caused by the coronavirus pandemic that have had a particularly big impact on neurology prescribing, as well as a continued challenge in persuading doctors to switch to the new class from older drugs like topiramate and AbbVie/Allergan’s Botox.

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Roots Analysis

JANUARY 29, 2024

The treatments / products provided by medical aesthetics companies used for facial aesthetic procedures have been mentioned below: Botulinum toxin: It is a toxin produced by a bacterium, Clostridium botulinum , commonly referred to as Botox. This treatment is primarily used on the face to weaken facial muscles, reducing wrinkles.

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pharmaphorum

MARCH 2, 2022

The lead drug is currently in a phase 1b study and is being developed for cognitive impairment and other symptoms associated with a range of neuropsychiatric and neurodegenerative disorders, such as Alzheimer’s and major depressive disorder.

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The Pharma Data

SEPTEMBER 8, 2021

–Results from a post-hoc analysis of the Phase 3 PREEMPT trials evaluate the use of BOTOX® (onabotulinumtoxinA) for chronic migraine –These data further demonstrate AbbVie’s commitment to harnessing and sharing innovative science and working to advance treatment options for people with migraine across the migraine spectrum.

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pharmaphorum

NOVEMBER 18, 2020

The decision is based on trials comparing Emgality with placebo which showed that the antibody halved the number of monthly migraine headache days for up to 40% of adults with migraine who had previously tried three or more prior medicines, such as Allergan’s Botox (botulinum toxin type A) or topiramate.

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pharmaphorum

NOVEMBER 18, 2020

The decision is based on trials comparing Emgality with placebo which showed that the antibody halved the number of monthly migraine headache days for up to 40% of adults with migraine who had previously tried three or more prior medicines, such as Allergan’s Botox (botulinum toxin type A) or topiramate.

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Trialfacts

JANUARY 23, 2024

radiotherapy) in the past 6 months Must not have performed any aesthetic treatment on the face within the past 12 months, including injections (fillers/ Botox/ permanent implants, etc.),

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pharmaphorum

FEBRUARY 12, 2021

Though most people will know of these toxins through Allergan’s ‘Botox’ brand name and its association with cosmetic surgery, they can be used for a wide variety of medical indications and are often used to relieve spasticity in patients following stroke, traumatic brain injury or other neurological conditions.

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The Pharma Data

NOVEMBER 2, 2020

There are a few medications approved to treat spasticity, including the generic baclofen and Botox. The stiffness in the muscles or involuntary jerking of the muscles can range from mild to severe. The FDA is expected to make a decision on Osmotica Pharmaceuticals’ arbaclofen extended release tablets for MS-associated spasticity in December.

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pharmaphorum

FEBRUARY 12, 2021

In 2020, Allergan opened a global Botox manufacturing facility in Westport, a tourist town on the west coast of Ireland and biotech company Regeneron established a biologic plant in Limerick. Pharma has always been a key sector for IDA Ireland.

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The Pharma Data

APRIL 30, 2021

Global Botox Cosmetic net revenues were $477 million , an increase of 44.7 Global Botox Therapeutic net revenues were $532 million , an increase of 7.0 Botox Cosmetic*. Botox Therapeutic*. Global net revenues from the aesthetics portfolio were $1.141 billion , an increase of 34.9 percent on a comparable operational basis.

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Roots Analysis

JANUARY 3, 2024

Medical Aesthetics encompasses a wide variety of treatments, including injectables, such as Botox, dermal fillers, chemical peels, aesthetic implants and professional laser hair removal and body contouring devices.

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The Pharma Data

AUGUST 1, 2021

Global Botox Therapeutic net revenues were $603 million, an increase of over 100.0 Global Botox Cosmetic net revenues were $584 million, an increase of over 100.0 AbbVie also presented real-world data on the role of Botox in combination with CGRP mAbs for Chronic Migraine prevention. percent on a reported basis, or 29.6

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The Pharma Data

FEBRUARY 4, 2021

– Full-Year Global Net Revenues from the Aesthetics Portfolio Were $2.590 Billion; Global Botox Cosmetic Net Revenues Were $1.112 Billion. – Full-Year Global Net Revenues from the Neuroscience Portfolio Were $3.496 Billion; Global Botox Therapeutic Net Revenues Were $1.387 Billion; Global Vraylar Net Revenues Were $951 Million.

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XTalks

JULY 5, 2022

Common anti-aging procedures include Botox or dermal fillers, which can reduce the appearance of wrinkles, sagging and increase volume in the face where desired. Everyone’s face changes with age, but due to constant innovations in technology, people can seek out options to slow or reverse the appearance of the process of aging.

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XTalks

AUGUST 2, 2023

percent increase since 2021, predominantly due to Botox sales for therapeutic uses. 2) Botox Therapeutic/Cosmetic Botox, or botulinum neurotoxin, is a neurotoxic protein produced by the Clostridium botulinum bacteria. Botox is also used as therapeutic treatments for neck spasms, excessive sweating, lazy eyes and migraines.

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The Pharma Data

MAY 13, 2021

Splints, mouthguards, botox. All well-meaning, but all restricted to their own area of expertise. I doubt they really understand the root causes of TMJ. I, of course, knew even less. So I had to try it all. Nerve and muscle pain relief. Teeth filing, vagus nerve stimulation, surgery…. As each one failed, I moved on to the next.

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