XTalks

NOVEMBER 19, 2024

In clinical research, diversity is more than a prerequisite for a successful drug — it’s a critical component that enhances the validity and applicability of clinical trial outcomes. Diversity Action Plans have now moved from being a “nice-to-have” to a “must-have” in clinical trial designs.

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XTalks

JANUARY 24, 2025

The expansion will also contribute to building the province of Ontarios position as a global hub for life sciences and biotechnology. Additionally, AstraZeneca anticipates seven first Phase III clinical trial data readouts in 2025.In The acquisition was one of the largest research investments in a Canadian biotech firm.

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Velocity Clinical Research

JULY 17, 2025

Velocity Clinical Research, the leading fully integrated site organization, has announced a strategic partnership with Palantir Technologies to automate and streamline the notoriously complex payments reconciliation process in clinical trials. Automating the AR reconciliation process is a game-changer for clinical trial sites.

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STAT News

JULY 1, 2025

company Beckley Psytech significantly reduced symptoms of treatment-resistant depression in a mid-stage trial, newly released data show, raising expectations for a class of drugs racing toward potential approval by U.S. points on a standard clinical measure of depression called the MADRS scale at day 29, depending on dose. regulators. 

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XTalks

MAY 13, 2025

The landscape of clinical trials in neuropsychiatry is undergoing a paradigm shift. Biomarker-driven clinical trials represent a transformative shift in drug development, particularly in fields like neuropsychiatry, where traditional methods have contended with variability in patient response.

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Velocity Clinical Research

MARCH 23, 2025

Clinical trials have been steadily leaving the UK for years. of patients recruited to global trials were from the UK. Thats not to say we dont still have some clout (the UK ranks fourth globally for Phase II trials ), but the trending outflow needs to be addressed. In 2021, just 2.2%

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XTalks

JANUARY 16, 2025

BlueRock Therapeutics, a subsidiary of Bayer AG, is making waves in the treatment of Parkinsons disease by advancing its investigational cell therapy, bemdaneprocel, to a Phase III clinical trial. In the Phase I trial, 12 participants received the therapy and were observed for two years. As of 2023, there were approximately 2.7

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XTalks

OCTOBER 23, 2024

In this episode, Vera spoke with Morgan Hanger, Executive Director of the Clinical Trials Transformation Initiative (CTTI). CTTI is a public-private partnership dedicated to improving the quality and efficiency of clinical trials, with an ambitious “Transforming Trials 2030” vision.

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XTalks

DECEMBER 9, 2024

This shift not only prioritizes patient safety but also ensures that ineffective treatments are identified more quickly.

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Pharmaceutical Technology

JUNE 13, 2025

The vaccine, leveraging generalised modules for membrane antigens (GMMA) technology, has shown promise in clinical trials, meeting pre-set immunogenicity success criteria. Can pharma tariffs “Make America Manufacture Again”? Can pharma tariffs “Make America Manufacture Again”?

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XTalks

DECEMBER 12, 2024

Beatrice Doe-Printemps Historically, clinical trials have disproportionately excluded women, people of color and other marginalized groups, leading to results that may not be generalizable to the broader population. For instance, women of childbearing age were excluded from participation in early phase clinical trials in 1977.

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Clinical Trials Clinical Trials Clinical Research Trials 59

XTalks

MAY 15, 2025

Digital health is reshaping clinical research and care delivery by offering more comprehensive insights into patient health. In traditional clinical trials, endpoints measurable outcomes such as lab results, imaging studies or clinical assessments are collected during scheduled visits at the clinic.

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XTalks

OCTOBER 24, 2024

Trends in Psoriasis Research: Biologics, Biosimilars and New Therapies Recent innovations in biologics and biosimilars have transformed psoriasis care.

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XTalks

DECEMBER 4, 2024

Dr. Yu has also led numerous clinical trials. Subscribe to the Xtalks Life Science Podcast to never miss a new episode. He has developed numerous immunotherapies and nanotechnologies from his National Institutes of Health (NIH) funded laboratory. Yu is leading at Kairos Pharma to address cancer drug resistance.

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Drugs Life Science Clinical Trials Clinical Trials 59

XTalks

NOVEMBER 14, 2024

Kebilidi has a known safety profile from clinical trials. The FDA also authorized the SmartFlow Neuro Cannula, a specialized infusion device by ClearPoint Neuro, Inc., for this purpose. Treatment has been largely supportive until now, with no options to target the underlying cause.

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Gene Therapy FDA Approval Gene Clinical Trials 105

Velocity Clinical Research

JUNE 17, 2025

life science expertise and investment. But its success is by no means assured; to capitalize on this moment and assume clinical trial leadership, Europe must play its cards right.” Uncertainty Creates Clinical Trial Leadership Opportunity for Europe appeared first on Velocity Clinical Research.

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Clinical Trials Clinical Trials Trials Clinical Research 52

XTalks

MAY 13, 2025

Amy Franco Senior Director of Patient Liaisons Scout What this means is that patient experience is top priority, especially in clinical trials, where many patients still face steep logistical and financial hurdles just to participate. Comprehensive, CostFree Support Financial burdens often derail trial participation.

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Pharmaceutical Technology

JUNE 6, 2025

This acquisition is also a critical part of our wider strategy with M42 to deliver a pipeline of transformative therapies and establish a world-class life sciences hub in Abu Dhabi. Can pharma tariffs “Make America Manufacture Again”? Can pharma tariffs “Make America Manufacture Again”?

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XTalks

MARCH 14, 2025

mg), underperformed in its latest clinical trial, leading to a dip in the companys share price. In response to the trial outcomes, Novos shares declined by approximately 8% this week. Novo shared the latest data from the Phase III REDEFINE 2 trial evaluating the drug in overweight or obese patients with type 2 diabetes.

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XTalks

DECEMBER 3, 2024

Building on this history of success, Novocure recently revealed promising Phase III results from the PANOVA-3 clinical trial, marking a significant milestone in pancreatic cancer treatment.

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XTalks

MAY 12, 2025

They share insights on how digital tools transform participant experiences, site operations and automation in clinical trials. Integrated digital solutions replace traditional paper-based processes, enabling teams to access essential trial data on the go, coordinate across remote sites and streamline communication channels.

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XTalks

NOVEMBER 28, 2024

The ENCORE trial evaluated reboxetine’s long-term efficacy and safety through a six-month open-label phase followed by a three-week double-blind period. During the double-blind phase, patients continuing reboxetine had an average increase of only 1.32 weekly cataplexy attacks compared to 10.29 for those switched to placebo (p=0.017).

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Scienmag

JUNE 16, 2025

As this research progresses towards clinical trials, the prospect of replacing painful biopsies with a painless, rapid, and richly informative testing method offers a beacon of hope for millions worldwide.

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XTalks

FEBRUARY 4, 2025

Current Share Price: The announcement follows a $115 million Series D financing in December 2024, co-led by Frazier Life Sciences and Deep Track Capital, with participation from Janus Henderson Investors and Logos Capital.

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XTalks

DECEMBER 31, 2024

Hansa Biopharma plans to advance imlifidase to Phase III clinical trials to confirm its efficacy and safety in a larger patient population. Sweden-based Hansa is focused on developing immunomodulating biologic therapies for rare immunologic conditions using its first-in-class IgG cleaving platform.

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XTalks

JANUARY 7, 2025

In the pivotal V005 Phase II/III clinical trial, 67 percent of patients treated with Symvess retained primary patency (blood flow without intervention), and 72 percent maintained secondary patency (blood flow with some intervention) at 30 days post-implantation.

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XTalks

JANUARY 6, 2025

In clinical trials, Alyftrek demonstrated non-inferiority to Trikafta, showing similar improvements in lung function and a reduction in sweat chloride levels. While both drugs target the CFTR protein, Alyftrek expands treatment options by addressing 31 mutations unresponsive to Trikafta.

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Pharmaceutical Technology

JUNE 25, 2025

Over the past few decades, Alzheimer’s research and development (R&D) has seen a low success rate due to failure to demonstrate efficacy in clinical trials. Can pharma tariffs “Make America Manufacture Again”? Go deeper with GlobalData Reports Biosimilars in Pharmaceuticals: Peptide-based compositions for Alzh.

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Pharmaceutical Technology

JUNE 19, 2025

As well as advancing DT-101, the new capital injection will also support the progression of two gamma-aminobutyric acid type A (GABA A ) receptor modulators towards clinical trials in 2026. Can pharma tariffs “Make America Manufacture Again”? Can pharma tariffs “Make America Manufacture Again”?

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Scienmag

JUNE 13, 2025

DOI 10.1038/s41551-025-01370-3 Media Contact Dione Chew Agency for Science, Technology and Research (A*STAR), Singapore dione_chew@hq.a-star.edu.sg

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XTalks

MARCH 11, 2025

XTALKS WEBINAR: Redefining Womens Cancer Care: Delivering Smarter, Safer Clinical Trials Live and On-Demand: Thursday, April 10, 2025, at 11am EDT (4pm BST/UK) Register for this free webinar to explore innovative approaches to enhancing clinical trials for breast and gynecological cancers.

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XTalks

MAY 9, 2025

In the US, RDEB affects approximately 2,000 to 2,500 individuals, many of whom face chronic pain, infections, disfigurement and shortened life expectancy. Attendees will gain insight into how to effectively integrate the patient voice throughout the clinical trial lifecycle.

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Pharmaceutical Technology

JUNE 24, 2025

Can pharma tariffs “Make America Manufacture Again”?

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XTalks

DECEMBER 26, 2024

Menarini Group has announced positive topline data from the Phase III BROADWAY and TANDEM clinical trials, evaluating obicetrapib and the fixed-dose combination of obicetrapib with ezetimibe. Meanwhile, the TANDEM trial evaluated a fixed-dose combination of obicetrapib with 10 mg ezetimibe in a similar patient population.

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XTalks

APRIL 7, 2025

Optum Life Sciences expert provides insights on the latest trends. For manufacturers developing GLP-1s or in the market, its invaluable to understand the nuances of how real-world evidence (RWE) can be harnessed to demonstrate the clinical and economic value of weight loss medications.

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XTalks

JULY 8, 2025

In today’s complex clinical trial environment, site success depends on more than protocol adherence — it requires targeted support that addresses the realities of site operations. The Realities of Patient Recruitment and Retention Patient recruitment has become one of the most challenging aspects of conducting clinical trials.

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XTalks

NOVEMBER 7, 2024

Emrosi’s approval was based on data from a pair of Phase III clinical trials for the treatment of rosacea. The trials met all co-primary and secondary endpoints, with participants having successfully completed the 16-week treatment with no significant safety issues.

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