Scienmag

JULY 1, 2025

This immunomodulation results in impaired phagocytic activity and cytokine secretion patterns that fail to contain infections effectively. Proteins governing the recruitment, activation, and differentiation of alveolar macrophages and neutrophils—frontline defenders against respiratory infections—were found to be dysregulated.

Protein 59

Protein Research Bioinformatics Medicine 59

The Pharma Data

JUNE 19, 2025

Traditionally, clinicians have addressed AFD with standard-of-care treatments such as fresh frozen plasma (FFP) or cryoprecipitate, both of which are blood products containing varying and often unpredictable concentrations of fibrinogen. Fresh frozen plasma is similarly logistically complex and contains lower concentrations of fibrinogen.

Containment 40

Containment Trials Clinical Trials Clinical Trials 40

Scienmag

JUNE 24, 2025

Hypothalamic neurons containing ERα and ERβ integrate hormonal and nutrient signals to adjust appetite, energy expenditure, and glucose metabolism. Meanwhile, in pancreatic beta cells, estradiol receptor engagement safeguards cell survival and insulin secretion, counteracting the deleterious effects of metabolic stress.

Hormones 80

Hormones Insulin Regulation Gene 80

Scienmag

JULY 16, 2025

By scrutinizing single-shot spectra collected over thousands of pulses, the researchers mapped out the statistical distribution of these spikes, revealing that each pulse contains between 18 to 30 energy spikes, typically clustering around 23. These spikes collectively span an energy bandwidth of roughly 7.5

Research 84

Research Containment Engineer Development 84

The Pharma Data

JUNE 15, 2025

Genmab, together with its collaborators, is committed to improving outcomes for patients with hematologic malignancies through innovative medicines. The strong data presented today further exemplify their ability to translate cutting-edge science into effective, patient-centric therapeutic strategies. Source link

Antibody 40

Antibody Trials Containment Clinical Trials 40

The Pharma Data

JUNE 11, 2025

FDA Approves Tablet Formulation of BeOne’s BRUKINSA® for All Approved Indications, Offering Greater Convenience for Patients with B-cell Cancers BeOne Medicines Ltd. Each tablet contains 160 mg of zanubrutinib, meaning patients will now only need to take two tablets per day, as opposed to four of the previous 80 mg capsules.

FDA Approval 40

FDA Approval Bioequivalency Marketing Medicine 40

Scienmag

JUNE 6, 2025

Alongside isotopic measurements, researchers meticulously collected 24-hour dietary recall data to rigorously quantify intake of foods and beverages containing added sugars, dairy, fruits, vegetables, and protein. Intriguingly, results diverged sharply by age group. American Journal of Clinical Nutrition , [DOI:10.1016/j.ajcnut.2025.02.013].

Research 89

Research Protein Containment Medicine 89

Scienmag

JUNE 13, 2025

Tom Seegar, PhD, Ohio Eminent Scholar and assistant professor in the Department of Molecular and Cellular Biosciences in the College of Medicine, serves as corresponding author of the study. It’s the first publication to come out of the Seegar Lab at UC. We are indebted to UC,” said Seegar.

Research 98

Research Protein Life Science Regulation 98

Scienmag

JUNE 19, 2025

In animal models, nicotine exposure has been demonstrated to downregulate CDGSH iron-sulfur domain-containing protein 3 (CISD3), impairing mitochondrial efficiency and heightening oxidative stress. Intrinsic mitochondrial dysfunction characterizes this apoptotic escalation.

Protein 52

Protein Regulation Gene Gene Editing 52

Pharmaceutical Technology

JUNE 6, 2025

Find out more Ro5’s platform utilises a biomedical knowledge graph containing more than 85 million nodes and 400m relationships to find new connections in biological processes and enable evaluation of drug targets based on therapeutic, biological and market potential. Data Insights The gold standard of business intelligence.

Drugs 130

Drugs Clinical Trials Clinical Trials Life Science 130

Drug Patent Watch

JANUARY 14, 2025

It’s being used extensively to reduce development costs and accelerate access to medicines[3]. Personalized Medicine As we move towards more personalized medicine, generic drug developers will need to find ways to adapt their products to individual patient needs. Sources cited: [link] [link] [link] [link] [link] Source

Generic Drugs 71

Generic Drugs Development Drugs Manufacturing 71

STAT News

JUNE 20, 2025

Fit into temperature-controlled air cargo containers, the pharmaceutical ingredients have had a huge impact on the U.S. health agency reiterated that the limited benefits of a pair of new Alzheimer’s drugs do not justify their high prices, meaning the medicines will not be made available through the U.K. trade imbalance.

Gene Therapy 67

Gene Therapy Regulation Gene Hormones 67

Pharmaceutical Technology

JUNE 9, 2025

Analysis includes innovative medicines with approved indications or indication extensions that were reimbursed since 2021. Factors assessed include the ratio of approved medicines to those that are reimbursed, volume of products reimbursed per year, and time to pricing and reimbursement. Patient profiles were counted distinctly.

Marketing 130

Marketing Branding Clinical Trials Clinical Trials 130

Pharmaceutical Technology

JULY 2, 2025

As cell and gene therapies contain living materials, the end-to-end supply chain contains far greater complexities than standard pharmaceuticals. Given the sensitivity of cell and gene therapy products, the capacity to offer a variety of storage and transportation options is imperative to meet specific requirements.

Gene Therapy 130

Gene Therapy Gene Clinical Trials Clinical Trials 130

Pharmaceutical Technology

JULY 10, 2025

Leveraging over 35 years of experience with high-potent molecules, their core strengths include two specialised contained manufacturing facilities and a purpose-built high-containment packaging facility, ensuring the safe handling and processing of high-potency drugs.

Bioavailability 130

Bioavailability Protein Development Manufacturing 130

XTalks

MAY 22, 2025

Early Clinical Data Early clinical results from Sernovas Phase I/II trial which is assessing the safety, tolerability and effectiveness of their implantable bio-hybrid organ transplant system containing donor islets in individuals with T1D are promising.

Clinical Research 52

Clinical Research Insulin Research Hormones 52

STAT News

JUNE 26, 2025

Today, we uncover the extent of low-quality generic cancer medicines disseminated globally, see ACIP prepare to raise new questions about vaccines approved long ago, and more. Others contained too much. Want to stay on top of the science and politics driving biotech today?  Continue to STAT+ to read the full story…

Drugs 78

Drugs Containment Vaccination Vaccine 78

Scienmag

JULY 9, 2025

As science continues to unravel the complexities of the gut-brain axis, studies like this emphasize the ENS’s pivotal role, demonstrating that the gut itself contains neural circuits with sophisticated integrative properties.

Research 52

Research Regulation Containment Genetics 52

PharmTech

JULY 16, 2025

Topics include: brain delivery via formulation and physical mechanisms novel vehicles for genetic medicine administration ADCs and bioconjugation strategies tissue-specific targeting for nucleic acid therapeutics manufacturing scale-up strategies for clinical and commercial readiness sustainability in drug and device development.

Drug Delivery 52

Drug Delivery Drugs Manufacturing Development 52

pharmaphorum

JUNE 30, 2025

Currently, only symptomatic therapies, such as anti-seizure medicines, are available to help treat people living with GRIN-NDD, and the burden of disease is devastating. Some examples are EMA Priority Medicine (PRIME) and FDA Orphan Drug and Breakthrough Therapy designations, both of which we were pleased to receive recently for radiprodil.

Sales 52

Sales Marketing Genetics Life Science 52

PharmTech

JULY 1, 2025

Reaction to changing market demands Key Takeaways ten23 health has joined the Alliance for RTU to support advancements in sterile, ready-to-use container technologies for aseptic drug manufacturing. Gerresheimer is] becoming an organization that focuses on solutions in specific domains,” Verheyden said in the interview (3). “We References 1.

Manufacturing 45

Manufacturing Packaging Packaging Containment 45

Pharmaceutical Technology

JULY 10, 2025

Indena has a long history of producing active pharmaceutical ingredients under GMP conditions, from the clinical (I, II, III) to the commercial phases, and combines that expertise with world-class containment facilities for HPAPIs. The strategic investments to expand specialist capabilities go further.

Manufacturing 130

Manufacturing Containment Marketing Gene Therapy 130

The Pharma Data

JUNE 6, 2025

Drivers of Market Growth: From Precision Medicine to Cost Optimization The shift toward targeted therapies , rare diseases , and personalized medicine is fundamentally altering pharmaceutical commercialization strategies. Cost containment also plays a pivotal role in fueling the CSO market.

Sales 40

Sales Compliance Branding Marketing 40

Roots Analysis

JANUARY 27, 2025

However, even the latest and the most promising advances in modern medicine have their own set of challenges and risks, which need to be addressed to ensure continued growth. Such procedures require sterile and higher-grade clean rooms, along with regular checks on containment levels.

Manufacturing 40

Manufacturing Contamination Gene Therapy Production 40

STAT News

JUNE 27, 2025

Enjoy, and see you soon… A fast-growing group of Americans is turning to what many call the “gray market” for obesity medicines, bringing cheap active ingredients from China often labeled as for research purposes , Reuters writes, citing import data and social media postings. Well, whatever you do, have a grand time.

Marketing 64

Marketing Drugs Vaccination Vaccine 64

Scienmag

JULY 10, 2025

categorized more than 10,000 plastic-related substances into 28 distinct groups, each embodying clear commonalities in chemical structure and containing a minimum of ten member chemicals. Diving deeper into the data assembled during their study, Monclús et al. Notably, some groups displayed an alarmingly high concentration of concern.

Regulation 59

Regulation Scientist Containment Research 59

Scienmag

JUNE 26, 2025

A 20-gram sample representative of household and industrial plastic debris — encompassing items like polystyrene foam, PLA straws, PU tubing, PC masks, PVC bags, PET bottles, PE droppers, and PP containers — was subjected to the newly developed orthogonal transformation process.

Production 97

Production Contamination Research Containment 97

Scienmag

JULY 9, 2025

A recent groundbreaking study has shed light on one such polyploid wild relative of barley, Hordeum bulbosum , which intriguingly contains both diploid and tetraploid individuals that, despite their distinct genomic configurations, exhibit near-identical morphologies.

Genome 72

Genome Genomics Genetics Genotype 72

Scienmag

JUNE 8, 2025

Recent peer-reviewed research from Northwestern Medicine, published in the journal Pediatrics , investigates the potential risks and hidden costs associated with these widely consumed “Get ready with me” videos. One of the most striking findings of the study relates to the composition of these skincare routines.

Dermatology 78

Dermatology Production Research Allergies 78

Pharmaceutical Technology

JUNE 27, 2025

These personalised weight loss medicines, which are chemically identical to branded alternatives, are significantly cheaper. Unintended compounded price point Compounded drugs are custom-made and unbranded medications that contain the same active ingredient as a marketed drug, such as semaglutide or tirzepatide via a prescription.

Drugs 147

Drugs Pharmacy Marketing Branding 147

Scienmag

JULY 16, 2025

The research team also examined integrated job cells containing both immigrant and native workers, ruling out compositional biases due to job segregation. This comprehensive and meticulously executed investigation marks a significant advance in understanding labor market inequalities on a multinational scale.

Marketing 52

Marketing Research Containment Engineer 52

Pharmaceutical Technology

JUNE 6, 2025

Drug containment and delivery solutions provider SCHOTT Pharma has announced an investment of more than €100m ($114m) to expand its manufacturing capacity for sterile ready-to-use (RTU) cartridges at its site in Lukácsháza, Hungary. Credit: SCHOTT Pharma. Sign up for our daily news round-up!

Manufacturing 130

Manufacturing Clinical Trials Clinical Trials Marketing 130

pharmaphorum

JULY 1, 2025

Other recommendations include finalising the development of a digital version of the red book, which contains child health records, so it can be easier for parents to keep track of immunisation schedules. "By Medical affairs is evolving. Understanding how to harness real-world data and digital insights is essential.

Doctors 66

Doctors Doctor Vaccine Vaccination 66

Scienmag

JUNE 11, 2025

The library contains several UT Extension publications and materials that focus on Tennessee, but users can access information from any state. People need to know that if a community prevents vector populations, they not only prevent bites but also prevent the onset of disease,” Trout Fryxell stresses. Global problems are local problems.

Bacteria 81

Bacteria Containment Allergies Research 81

XTalks

JUNE 11, 2025

The date also honors the birth anniversary of Austrian-American biologist and physician Karl Landsteiner whose discovery of the ABO blood group system in the early 20th century revolutionized medicine and made blood transfusion a safe and routine procedure.

Production 59

Production Medicine Containment Clinical Trials 59

Pharmaceutical Technology

JUNE 24, 2025

Compounded drugs are custom-made and unbranded medications that contain the same active ingredient as a marketed drug. Hims & Hers’ revenue has been soaring on the back of its compounded glucagon-like peptide-1 receptor agonist (GLP-1RA) sales.

Marketing 130

Marketing Manufacturing Clinical Trials Clinical Trials 130

Medical Xpress

JUNE 23, 2025

Wood, director of Northeastern Universitys Extreme Medicine Certificate Program, says its important for people to recognize the signs of heat illness and how quickly heat exhaustion can progress to heat stroke, when immersion in cold water is necessary to save lives. He also advises people to check their urine color for signs of dehydration.

Gerontology 55

Gerontology Engineer Radiology Cardiology 55