AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 2, 2022

Scientists have discovered DNA-damaging molecules made by gut bacteria that may help explain why people with inflammatory bowel disease (IBD) have higher rates of colorectal cancer than those without the condition.

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DNA Bacteria Scientist Research 189

BioPharma Reporter

JANUARY 24, 2024

We took the time to speak with Amy Walker, vice president at 4basebio, to discuss the merits of synthetic DNA and its future application.

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DNA Development 104

AuroBlog - Aurous Healthcare Clinical Trials blog

OCTOBER 17, 2022

Studies in mammals have shown that the ‘memories’ of various environmental effects – such as diet, weight, and stress – can be passed on from fathers to offspring, despite these effects not being coded for in the DNA sequences carried by sperm.

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DNA Clinical Trials Clinical Trials Clinical Research 208

AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 1, 2023

The Drug Controller General of India (DCGI) has added in-vitro diagnostic (IVD) medical devices including those for diagnosis of Covid-19, ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) extraction kits, among others into the Class C risk category under the Medical Devices Rules (MDR), 2017.

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RNA DNA In-Vitro Drugs 165

Drug Discovery World

NOVEMBER 20, 2023

Raquel Sanches-Kuiper , Vice President of Science and Applications at Evonetix, and Clare Whitewoods , Marketing Communications Manager at Evonetix, look at the benefits synthetic DNA brings to pharmaceutical development.

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DNA Engineer Antibody Gene 69

Drug Discovery World

JANUARY 23, 2024

” The ability to collect and analyse such a new wealth of ocean data comes from major developments in DNA sequencing technology and computational power. The post World’s largest catalogue of ocean DNA could boost drug discovery appeared first on Drug Discovery World (DDW).

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DNA Drugs Gene Scientist 103

pharmaphorum

JULY 20, 2022

It has suspected for many years that some diseases may be linked to non-coding or ‘junk’ DNA, but the mechanism behind the pathology hasn’t been worked out. Junk DNA is a term used to describe the 97% of the genetic sequence in human cells found between the 3% coding for our 20,000 genes, once thought to be inert.

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DNA Scientist Genome Genomics 113

Scienmag

JUNE 26, 2022

The monumental global task to restore degraded ecosystems will need to include sophisticated technologies such as environmental DNA monitoring to understand and support the recovery of complex biospheres, international researchers say.

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DNA Research Engineer 91

Medical Xpress

NOVEMBER 18, 2022

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

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DNA Scientist Vaccination Vaccine 91

Outsourcing Pharma

SEPTEMBER 8, 2023

A benchtop DNA sequencer developed by the U.S. DNA sequencing company Element Biosciences, Inc., has seen sales grow by triple digits and has received more than 100 orders since its launch in March 2022.

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DNA Sales Development Regulation 83

Medical Xpress

MAY 14, 2023

For two decades, scientists have been comparing every person's full set of DNA they study to a template that relies mostly on genetic material from one man affectionately known as "the guy from Buffalo."

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DNA Scientist Genome Genomics 98

Pharma Times

OCTOBER 4, 2022

University of Lincoln and the University of Sheffield are researching how DNA could be repaired

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DNA Research 149

Pharma Times

MAY 10, 2023

Transfer marks start of vital development stage as company expands its range of synthesized DNA

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DNA Development 114

Pharma Times

NOVEMBER 29, 2022

Bill & Melinda Gates Foundation grant will boost potential of nanoparticle-formulated doggybone DNA

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DNA Vaccination Vaccine 127

Medical Xpress

FEBRUARY 22, 2023

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

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DNA Research Protein Gene 98

BioPharma Reporter

FEBRUARY 2, 2023

mRNA pioneer BioNTech has completed construction of its first proprietary plasmid DNA manufacturing facility in Marburg, Germany.

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DNA Manufacturing 112

Drug Discovery World

MAY 11, 2023

The first DNA synthesised using Evonetix’s semiconductor chip technology has been delivered to the Department of Chemical Engineering and Biotechnology at the University of Cambridge. The DNA was delivered to Dr Jenny Molloy, Co-chair of the Engineering Biology Interdisciplinary Research Centre at the University of Cambridge.

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DNA Engineer Gene Scientist 52

Scienmag

JULY 19, 2022

Scientists have found that non-coding ‘junk’ DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the way of the replication and repair of our genome, potentially allowing mutations to accumulate.

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DNA Genome Genomics Scientist 68

Medical Xpress

MAY 16, 2023

Cancer is caused by DNA changes that cause a cell to gradually change from benign to malignant. By studying the types of DNA changes and the consequences of the changes, important insights into the underlying biological processes were obtained. This can lead to metastases in other parts of the body.

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DNA Research 98

Scienmag

APRIL 7, 2022

Chemists integrated computer functions into rolling DNA-based motors, opening a new realm of possibilities for miniature, molecular robots. Nature Nanotechnology published the development, the first DNA-based motors that combine computational power with the ability to burn fuel and move in an intentional direction.

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DNA Development Engineer 91

Medical Xpress

FEBRUARY 22, 2023

A new research paper was published in Aging, titled "Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity."

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DNA Genome Genomics Research 97

Outsourcing Pharma

JULY 18, 2023

company KSQ Therapeutics to co-develop KSQâs lead cancer drug, which is designed to sabotage the DNA repair mechanisms of cancer cells. Roche has entered a licensing and collaboration deal with the U.S.

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DNA Licensing Licensing Drugs 84

Drug Discovery World

DECEMBER 4, 2023

A novel DNA vaccine in combination with chemotherapy has demonstrated promising clinical results against a deadly form of ovarian cancer. The investigational compound Elenagen is an experimental DNA therapy that consists of a circular piece of DNA called a plasmid that includes a gene for a human protein called p62/SQSTM1.

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DNA Packaging Packaging Vaccination 59

Scienmag

NOVEMBER 30, 2021

30, 2021 — A new study led by University of California, Irvine researchers has confirmed a link between altered DNA repair and increased DNA damage associated with spinocerebellar ataxia type 7 (SCA7), a debilitating, sometimes deadly neurodegenerative condition causing movement disorders. Irvine, Calif.,

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DNA Research Medicine 92

Drug Discovery World

MAY 24, 2023

Touchlight, a company providing DNA services and manufacturing enzymes, has completed the redevelopment and expansion of its UK manufacturing facility in London, UK. The expanded facility’s manufacturing capacity has tripled and is now capable of producing more than 8kg a year.

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DNA Gene Editing Gene Therapy Genetics 52

Scienmag

JUNE 3, 2022

Researchers in Japan have discovered that the local DNA motion inside of human cells remains steady throughout interphase, where the cell grows and replicates its DNA for cell division. The study suggests that this steady-state DNA motion allows cells to conduct housekeeping tasks under similar environments during interphase.

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DNA Research 80

Scienmag

MAY 9, 2022

HOUSTON – (May 9, 2022) – When cells reproduce, the internal mechanisms that copy DNA get it right nearly every time. Rice University bioscientists have uncovered a tiny detail that helps understand how the process could go wrong.

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DNA 86

Scienmag

JUNE 3, 2022

Of these various macromolecules that form droplets, DNA is quite interesting because it is predictable and programmable, which are qualities useful in nanotechnology. Recently, the programmability of DNA was used to construct and regulate DNA droplets […].

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DNA Life Science Regulation Research 75

BioPharma Reporter

FEBRUARY 6, 2023

AstraZeneca has cut the cost and time needed to complete DNA synthesis by integrating an assembly framework into Benchling.

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DNA Clinical Development Development 98

Pharma Times

AUGUST 16, 2022

Researchers are invited to apply to receive DNA that has been synthesised using Evonetix’s platform

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DNA Research 98

Medical Xpress

NOVEMBER 17, 2022

BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instances, leading to breast and ovarian cancer, plays an important role in the body's DNA repair mechanisms. BRCA1, once mutated, can cause cancer to develop.

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DNA Production Gene Development 119

Bio Pharma Dive

JANUARY 4, 2024

Moonwalk Biosciences, the latest biotech cofounded by the gene editing scientist, joins other startups aiming to alter gene expression without changing DNA.

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Gene Editing Gene Expression DNA Gene 350

Medical Xpress

APRIL 17, 2023

A multi-institution study that included researchers from Stanford University, the University of California at San Diego, the University of Cambridge, the Fred Hutchinson Cancer Center and others has looked into the development of extrachromosomal DNA in patients with esophageal adenocarcinoma or Barrett's esophagus.

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DNA Development Research 89

BioPharma Reporter

AUGUST 2, 2021

With Scancell taking its DNA-based COVID-19 vaccine tech into clinical trials this year, it is already focusing its attention on the techâs potential to be used as a needle-free booster shot to address Variants of Concern.

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DNA Vaccination Vaccine Clinical Trials 137

STAT News

JANUARY 10, 2023

Illumina, the largest maker of DNA sequencing technology, told investors exactly what they didn’t want to hear on Monday. For years, Illumina shares rose steadily as the company led the way on pushing down the costs involved in doing genetic research.

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DNA Genetics Research 105

pharmaphorum

AUGUST 23, 2021

The COVID-19 pandemic accelerated the development of mRNA-based vaccines, and its influence has now extended to DNA-based shots as well, with Zydus Cadila’s ZyCoV-D getting emergency use authorisation in India. Proponents of the approach claim that DNA vaccines may have advantages over other technologies like mRNA.

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DNA Vaccination Vaccine Genetic Engineering 98

STAT News

FEBRUARY 9, 2023

Or the baby girl who could have had a life-threatening reaction to anesthesia had researchers not sequenced her DNA ahead of time. They’ll tell you about the 3-month-old boy whose heart was failing until researchers pinpointed what was ailing him.

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Genetic Disease DNA Genetics Genome 119