Roots Analysis

FEBRUARY 21, 2022

Advancement in DNA sequencing technologies have resulted in noteworthy developments in various healthcare-related research fields, such as diagnostics and personalized medicine. Moreover, the manual protocols require extensive manipulation, costly reagents and long duration of skilled genomic library production.

Marketing 52

Marketing Gene Sequencing DNA Genome 52

The Pharma Data

AUGUST 19, 2021

The VENTANA MMR RxDx Panel is the first companion diagnostic test to aid in identifying patients whose solid tumours are deficient in DNA mismatch repair (MMR), who may be eligible for JEMPERLI (dostarlimab-gxly) monotherapy, an anti-PD-1 immunotherapy from GSK. 4,5,6 PD-1 inhibitors can be effective in cancers with MMR deficiency.

FDA Approval 52

FDA Approval DNA Reagent Protein 52

Roots Analysis

FEBRUARY 23, 2022

Further, NGS library preparation kits offer several benefits, such as low requirement of starting material, generation of longer RNA / DNA sequences and production of superior quality nucleotide libraries, thereby, catering to existing unmet needs of the research domain. Next Generation Sequencing (NGS) Library Preparation Kits.

Genetics 52

Genetics DNA RNA Reagent 52

Drug Discovery World

SEPTEMBER 29, 2022

Minimising reagent consumption and costs. How much time to prepare sufficient materials and reagents for screening? During a 2021 webinar on optimising assay development for hit identification, a survey asked over 50 drug discovery scientists, “Which goal is the highest priority when developing a drug discovery assay?”. Conclusion.

Reagent 52

Reagent DNA Scientist Drugs 52

Roots Analysis

OCTOBER 16, 2023

DNA cloning refers to the process of generating multiple copies of a particular DNA segment. DNA and Gene Cloning involves the isolation of a DNA sequence of any species ( often a gene ) and its insertion into a vector to enable growth without any alteration in the original DNA sequence.

DNA 40

DNA Gene Protein In-Vitro 40

The Pharma Data

JANUARY 31, 2021

Illumina , the world’s leading DNA sequencing and array-based technologies company, is partnering with Sequoia Capital China, an investment firm, to launch a life sciences incubator in China. It is dubbed the Sequoia Capital China Intelligent Healthcare Genomics Incubator, Powered by Illumina.

Life Science 52

Life Science Genome Genomics Reagent 52

Drug Discovery World

SEPTEMBER 28, 2022

Winners will be evaluated based on criteria that include research objective, genomic reagent request, and how the product would be used in the field of research. . Grant program research areas include nucleic acid extraction, liquid biopsy, long-read sequencing, and genomics applications.

Genome 52

Genome Genomics Research Life Science 52

Roots Analysis

AUGUST 15, 2023

Further, other improvements, including efficient production cycles, use of low-cost reagents and development of purified component platforms, have made cell free biomanufacturing a preferred option for synthesis of various types of biologics and small molecules.

Protein 52

Protein In-Vitro Production Reagent 52

Drug Discovery World

SEPTEMBER 14, 2023

If you perform all of your tasks manually, you may need to stop your initial run partway through, which means losing the reagents and samples with which you have already begun working. Automation can track logistics, such as adding reagents to a recurring order after a certain amount is used up.

Reagent 111

Reagent Life Science Scientist DNA 111

Drug Discovery World

JUNE 28, 2023

Many automation solutions can perform several different tasks and can be paired with other equipment to automate a range of tasks, such as DNA extraction and sequencing, PCR, and Western blots. Automation can track logistics, such as adding reagents to a recurring order after a certain amount is used up.

Reagent 98

Reagent Life Science Scientist DNA 98

The Pharma Data

JANUARY 31, 2021

NASDAQ: ILMN), the global leader in DNA sequencing and array-based technologies, and Sequoia Capital China , a leading investment firm, today announced a collaboration to catalyze the startup ecosystem in China with the launch of the Sequoia Capital China Intelligent Healthcare Genomics Incubator, Powered by Illumina. .”

Genome 52

Genome Genomics Life Science DNA 52

pharmaphorum

JUNE 1, 2021

Two different types of microtaggants are now available, one produced from non-biologic DNA and the other from silica: DNA microtaggants. DNA is robust and easy to detect and because it is possible to produce different versions of the same DNA molecule, it can be made regional, product, or company-specific.

Medicine 52

Medicine DNA Pharmacy Production 52

Drug Discovery World

JANUARY 19, 2023

This paid-for advertorial by Catalent appeared in DDW Volume 24 – Issue 1, Winter 2022/2023 One significant challenge in the manufacturing of cell and gene therapies is the production of high-quality plasmid DNA (pDNA). billion by 2030 (BioSpace, 11 August 2022). billion by 2030 (BioSpace, 11 August 2022).

DNA 52

DNA Manufacturing Gene Therapy Gene 52

Drug Discovery World

SEPTEMBER 29, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. In this presentation, a review of the results from scaling up the IVT reaction from μg to gram scale mRNA yield will be presented.

In-Vitro 52

In-Vitro Reagent DNA Drugs 52

Pharmaceutical Technology

FEBRUARY 3, 2023

The established method for this process is a triple transfection using three different DNA plasmids. Better transfection reagents and efforts to automate the currently highly manual and inconsistent process could also make a difference, he adds. For example, researchers have developed a two-plasmid cotransfection system.

Genome 244

Genome Genomics Medicine Gene Therapy 244

Drug Discovery World

NOVEMBER 2, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. In this presentation, a review of the results from scaling up the IVT reaction from μg to gram scale mRNA yield will be presented.

In-Vitro 52

In-Vitro Reagent DNA Production 52

Drug Discovery World

OCTOBER 23, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. In this presentation, a review of the results from scaling up the IVT reaction from μg to gram scale mRNA yield will be presented.

Production 52

Production In-Vitro Reagent DNA 52

Drug Discovery World

OCTOBER 16, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. In this presentation, a review of the results from scaling up the IVT reaction from μg to gram scale mRNA yield will be presented.

In-Vitro 52

In-Vitro Reagent DNA Production 52

Drug Discovery World

OCTOBER 9, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. In this presentation, a review of the results from scaling up the IVT reaction from μg to gram scale mRNA yield will be presented.

In-Vitro 52

In-Vitro Reagent DNA Production 52

Drug Discovery World

OCTOBER 2, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. In this presentation, a review of the results from scaling up the IVT reaction from μg to gram scale mRNA yield will be presented.

In-Vitro 52

In-Vitro Reagent DNA Production 52

pharmaphorum

FEBRUARY 3, 2021

However, caveats surrounding the stochastic off-target outcomes of cleaving both strands of the DNA helix to elicit a gene modification remain a source of concern. Traditional CRISPR-Cas9 technology relies on generating a DSB in the DNA to facilitate a genetic modification. Base editing to get cell therapies on point.

Gene Editing 97

Gene Editing Gene DNA Engineer 97

Drug Discovery World

MAY 16, 2023

Lending to the time-to-clinic discrepancy, we also see increasing demands on manufacturing capacity for CGT reagents.” Furthermore, providing the flexibility needed to ramp manufacturing up or down depending on demand cycles has become more critical.”

Gene Therapy 52

Gene Therapy Gene Manufacturing Marketing 52

The Pharma Data

JULY 11, 2021

TAKHZYRO is produced in Chinese Hamster Ovary (CHO) cells by recombinant DNA technology. The reagents used in the aPTT laboratory test initiate intrinsic coagulation through the activation of plasma kallikrein in the contact system. Inhibition of plasma kallikrein by lanadelumab can increase aPTT in this assay.

Allergies 52

Allergies Antibody Recombinant DNA Technology Production 52

Drug Discovery World

JULY 18, 2023

Rolf Turk , Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. Nucleic acid-based diagnostics, which typically require PCR reagents and laboratory equipment, are crucial for identifying, treating, and preventing common infectious diseases.

DNA 98

DNA Genome Genomics RNA 98

The Pharma Data

MARCH 20, 2021

The Challenge: The demands of many labs simultaneously beginning COVID-19 screening programs are leading to a scarcity of resources like pipette tips and reagents. delays where reagents are in. DNA biomarker services in an accredited environment. significant miniaturization and reduction in reagent. The MANTIS.

Reagent 52

Reagent RNA Bioinformatics Medicine 52

Roots Analysis

FEBRUARY 13, 2023

It transfers genetic information form to DNA to ribosomes, a specialized structure, or organelle, which decodes genetic information into a protein. In addition to this, more than 95 mRNA synthesis kits, that contain reagents for the synthesis of research grade mRNAs, are currently available in the market.

Manufacturing 52

Manufacturing Drug Delivery Systems Genetic Engineering RNA 52

Drug Discovery World

DECEMBER 15, 2022

These platforms all induce double strand cuts in the chromosomal DNA that can be sealed by the cell, leading to a specific gene disruption, or resulting in a new target site for inserting DNA segments. Reduce/eliminate chromosomal disruptions caused by double-strand DNA breaks. In one example, Choi et al.

Gene Editing 52

Gene Editing Gene In-Vivo Genome 52

Drug Discovery World

OCTOBER 21, 2022

Accordingly, advances in flow cytometry technology – both in instrumentation and reagent offerings – are enabling researchers to decipher these questions, leading to new discoveries and diagnostic tools. . Reagents produced under ISO certification provide an extra level of traceability to support internal documentation and quality assurance.

Reagent 52

Reagent Antibody Drugs Protein 52

The Pharma Data

DECEMBER 2, 2020

Results show the protocol demonstrated a 30Gb+ yield of long DNA reads raw data of an E. The FMv8 protocol introduces a needle-aspirate-based, cell-resuspension step prior to cell lysis that boosts DNA recovery. Elsewhere around the globe: RevoluGen – U.K.-based

Drugs 52

Drugs Gene Editing Genome Genomics 52

Roots Analysis

AUGUST 28, 2022

As a result, industry and non-industry stakeholders, are on the lookout for advanced platforms that can simultaneously capture the arrangement of multiple biomolecules (DNA, RNA, proteins and others) with single-cell or subcellular resolution.

Genome 52

Genome Genomics RNA Genome Project 52

Drug Discovery World

NOVEMBER 30, 2023

coli expression systems and is using high-throughput expression pipelines to screen constructs for optimal expression to generate protein and cellular reagents. The Absolute Antibody team was available to discuss custom services, as well as the company’s comprehensive antibody reagent catalogue.

Antibody 59

Antibody Protein Engineer In-Vivo 59

Drug Discovery World

JUNE 6, 2023

The only way we’re going to do that was improved diagnostic techniques.” At the meeting, Jordan says we are seeing improvements in circulating tumour DNA, circulating tumour cell diagnosis, as well as ways of detecting tumours before they are detectable through standard methodologies, such as CT scans. It’s a 1.5

Protein 52

Protein DNA RNA Research 52

The Pharma Data

AUGUST 4, 2020

Accurate monitoring of Epstein-Barr virus DNA levels is critical, as they are associated with a range of life threatening-diseases including cancer in transplant patients. This is the first quantitative in vitro diagnostic test for Epstein-Barr virus (EBV) DNA in the United States. For more information, please visit www.roche.com.

DNA 52

DNA In-Vitro Medicine Reagent 52

Drug Discovery World

FEBRUARY 27, 2023

By focusing on workflow simplification and expanded assay capabilities in a state-of-the-art microplate reader, complemented by our optimised reagent technologies, our team has created an all-around high-performing system built for today and the future.”

Drugs 52

Drugs Life Science Protein Scientist 52

Drug Discovery World

FEBRUARY 8, 2023

This helps ensure a high concentration of loaded capsids and adequate removal of impurities, such as host cell proteins and DNA. In AAV therapeutics, empty capsids are those that are not packaged with the therapeutic DNA. A crucial part of the AAV workflow is the purification of viral vectors.

Gene Therapy 52

Gene Therapy Gene Antibody Production 52

The Pharma Data

SEPTEMBER 7, 2020

to obtain comparable results when measuring levels of BKV DNA. The test offers an alternative to lab-developed tests (LDTs) or Analyte Specific Reagent (ASR) combinations, potentially minimising variability and complexity in testing, reducing workload and alleviating risk for laboratories. IU/mL and an expanded linear range from 21.5

In-Vitro 52

In-Vitro Medicine Reagent DNA 52

Drug Discovery World

OCTOBER 14, 2022

Reducing assay volumes from about 200 µL to 1 µL ha s cut the quantities of reagents and consumables needed, while automation has replaced manual handling, so lowering running and personnel costs. . One of the other limiting factors for HTS – cost per well analysed – has also been addressed. Zuvela-Jelaska, T. Bretschneider, A.H.

Drugs 52

Drugs In-Vitro Development Production 52