Medical Xpress

NOVEMBER 30, 2022

Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair.

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Bio Pharma Dive

DECEMBER 12, 2023

Based on the work of MIT scientists, the well-funded startup is developing ways to insert large sizes of genetic material anywhere in the genome without damaging or breaking DNA.

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Drug Discovery World

JANUARY 23, 2024

Scientists at the King Abdullah University of Science and Technology (KAUST) in Thuwal, Saudi Arabia used the KAUST Metagenomic Analysis Platform (KMAP) to analyse massive amounts of sequencing data to release Global Ocean Gene Catalog 1.0.

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Scienmag

JANUARY 21, 2022

Scientists at the University of Bristol have developed new biological parts that are able to shape the flow of cellular processes along DNA. Credit: Thomas Gorochowski Scientists at the University of Bristol have developed new biological parts that are able to shape the flow of cellular processes along DNA.

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Drug Discovery World

NOVEMBER 20, 2023

Raquel Sanches-Kuiper , Vice President of Science and Applications at Evonetix, and Clare Whitewoods , Marketing Communications Manager at Evonetix, look at the benefits synthetic DNA brings to pharmaceutical development. Their speed also allows for their potential use in personalised therapy for diseases such as cancer.

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Scienmag

JULY 19, 2022

Scientists have found that non-coding ‘junk’ DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the way of the replication and repair of our genome, potentially allowing mutations to accumulate.

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Scienmag

DECEMBER 12, 2021

Scientists at Lund University have discovered for the first time that it is possible to detect insect DNA in the air. Using air from three sites in Sweden, insect DNA from 85 species could be identified. Credit: Fabian Roger Scientists at Lund University have […].

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Medical Xpress

MAY 4, 2023

In a study of 17 people from five families, Johns Hopkins Medicine researchers say they found that ultra-lengthy DNA endcaps called telomeres fail to provide the longevity presumed for such people.

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Bio Pharma Dive

JANUARY 2, 2024

The deal is the second startup sale engineered by University of California, Berkeley scientist Shakked Halperin, and gives Tome a way to insert or delete small DNA sequences into the genome.

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Pharmaceutical Technology

JULY 20, 2022

A close look at the virus also showed that the envelope protein has a small region that looks like human histones, which are protein complexes seen along DNA. The post Gladstone and UCSF scientists discover BET protein role in Covid-19 appeared first on Pharmaceutical Technology.

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XTalks

FEBRUARY 12, 2024

The ad pays homage to notable scientists throughout the times and also celebrates 175 years of Pfizer’s contributions to scientific innovation. There is a longer 90-second version of the ad from which the ad is cut from. Pfizer said over time, the company has become “a part of the fabric of history and healthcare.”

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Scienmag

SEPTEMBER 15, 2021

Scientists from the University of Bradford have discovered a DNA protein ‘switch’ that could help in the treatment of cancer and dementia. Credit: University of Bradford Scientists from the University of Bradford have discovered a DNA protein ‘switch’ that could help in the treatment of cancer and dementia.

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Scienmag

DECEMBER 28, 2021

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects and repair genetic damage is at work to prevent DNA mutations and diseases such as […].

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Drug Discovery World

MAY 11, 2023

The first DNA synthesised using Evonetix’s semiconductor chip technology has been delivered to the Department of Chemical Engineering and Biotechnology at the University of Cambridge. The DNA was delivered to Dr Jenny Molloy, Co-chair of the Engineering Biology Interdisciplinary Research Centre at the University of Cambridge.

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Scienmag

SEPTEMBER 13, 2021

DNA is the instruction manual for every living organism, guiding the development and functioning of all biological processes. In essence, it is a molecule with a double helix structure with each unit of a helix containing what are known as “DNA bases”.

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Scienmag

NOVEMBER 2, 2021

In every advanced organism, the molecule called DNA (deoxyribonucleic acid, to use its full name) forms the genetic code.

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Bio Pharma Dive

SEPTEMBER 12, 2022

Scientists at Pretzel believe fixing mutated mitochondrial DNA with a mix of small molecule therapies and gene editing could be key to solving a number of hard-to-treat diseases.

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Drug Discovery World

DECEMBER 4, 2023

A novel DNA vaccine in combination with chemotherapy has demonstrated promising clinical results against a deadly form of ovarian cancer. The investigational compound Elenagen is an experimental DNA therapy that consists of a circular piece of DNA called a plasmid that includes a gene for a human protein called p62/SQSTM1.

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BioTech 365

MAY 14, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists reveal unprecedentedly versatile new DNA staining probe.A

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Drug Discovery World

JULY 19, 2022

Non-coding or ‘junk’ DNA could contribute to the development of certain cancers due to how it disrupts the replication of the genome, scientists have discovered. . A team from The Institute of Cancer Research (ICR), London reconstituted the entire process of DNA replication in a test tube in order to understand it more completely.

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Pharmaceutical Technology

SEPTEMBER 15, 2022

Scientists at the University of Birmingham in the UK have detected a possible drug target for the treatment of neurological ailments, such as Alzheimer’s disease (AD), and boosting nerve regeneration in central nervous system (CNS) injuries.

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Pharma Times

JULY 28, 2022

The British Heart Foundation’s ‘Big Beat Challenge’ grant of £30m for research into cardiovascular medicine was given to CureHeart

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Scienmag

MAY 11, 2021

Scientists investigate the evolution of Mimivirus, one of the world’s largest viruses, through how they replicate DNA Credit: Indian Institute of Technology Bombay 2003 was a big year for virologists.

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BioTech 365

JANUARY 31, 2022

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists use ‘sticky’ DNA to build organized structures of gel blocks.Researchers from the Okinawa Institute of Science and Technology Graduate University (OIST) have used microscopic strands of … Continue reading (..)

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BioTech 365

OCTOBER 19, 2021

Purigen Biosystems Enables Scientists to Extract and Purify Higher Yields of DNA from Fresh Frozen Tissue Samples Purigen Biosystems Enables Scientists to Extract and Purify Higher Yields of DNA from Fresh Frozen Tissue Samples New automated Ionic® Tissue to Pure … Continue reading →

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Scienmag

SEPTEMBER 7, 2020

Meta-DNA structures transform the DNA nanotechnology world Credit: Hao Yan A team* of scientists from ASU and Shanghai Jiao Tong University (SJTU) led by Hao Yan, ASU’s Milton Glick Professor in the School of Molecular Sciences, and director of the ASU Biodesign Institute’s Center for Molecular Design and Biomimetics, has just announced (..)

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Scienmag

JULY 12, 2021

USC researchers have achieved a better way to identify elusive DNA variants responsible for genetic changes affecting cell functions and diseases. Using computational biology tools, scientists at the university’s Dornsife College of Letters, Arts and Sciences studied “variable-number tandem repeats” (VNTR) in DNA.

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Scienmag

FEBRUARY 23, 2021

CRISPR gene editing has transformed research, but it is not perfect, and can sometimes target unintended genes; to watch CRISPR enzymes respond to different genes, Leipzig University researchers developed a new method using DNA origami and were able to me Credit: Image courtesy of Julene Madariaga Marcos.

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BioTech 365

MARCH 4, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: When the damage is done: How scientists tackle DNA damage repair.Damage to DNA is the basic cause of cancer. As you read this, many of your cells … Continue reading →

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Medical Xpress

NOVEMBER 30, 2022

In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides—the basic structural unit of DNA coded in the base of chemicals cytosine (C), adenine (A), guanine (G) and thymine (T)—is repeated multiple times in tandem.

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BioTech 365

FEBRUARY 23, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists use DNA origami to monitor CRISPR gene targeting.The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in Chemistry, sometimes cut in … Continue reading →

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Drug Discovery World

DECEMBER 14, 2023

The Federation of American Scientists (FAS) has published five policy recommendations to address the challenges of artificial intelligence (AI) in life sciences. The post The Federation of American Scientists addresses biosecurity risks of AI appeared first on Drug Discovery World (DDW).

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STAT News

NOVEMBER 30, 2022

The scientists sent the blood 950 miles east to Massachusetts General Hospital in Boston, to a tiny lab (recently converted from a storeroom) where a 28-year-old postdoc named James Gusella and his 23-year-old research technician, Rudolph Tanzi, got to work.

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Drug Discovery World

APRIL 24, 2024

The event will feature experts Daniel Jachimowicz, Senior Bioscience Scientist at AstraZeneca BioPharmaceuticals R&D, Sweden, and Bastian Schiffthaler, Senior Data Scientist at AstraZeneca BioPharmaceuticals R&D, Sweden. The event will be supported by Oxford Nanopore Technologies. The event will take place on 13 May, 4PM BST.

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Pharma Times

FEBRUARY 15, 2022

Francis Crick Institute and King’s College London collaborate to identify specialist cells which protect DNA

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pharmaphorum

DECEMBER 3, 2020

Germany’s Merck KGaA has joined with UK-based Artios Pharma in a potential multi-billion dollar deal to investigate novel DNA damage response targets in cancer. The principle of DNA damage response is already being exploited by AstraZeneca and other companies with their poly (ADP-ribose) polymerase (PARP) inhibitor drugs.

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Scienmag

APRIL 1, 2021

Salk scientists reveal new insights into neurodegenerative disorders and potential for genetic therapies Credit: Salk Institute/Waitt Advanced Biophotonics Center LA JOLLA–(April 1, 2021) Neurons lack the ability to replicate their DNA, so they’re constantly working to repair damage to their genome.

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