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Nektar lifted by Merck alliance for bempeg, new trial funding

pharmaphorum

Nektar Therapeutics is waiting on multiple data readouts for its lead drug bempegaldesleukin paired with strategic partner Bristol-Myers Squibb’s checkpoint inhibitor Opdivo, but that hasn’t stopped it signing up to test the drug with rival Keytruda from Merck & Co. .

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STAT+: ‘A blind eye’: NIH fails to ensure clinical trial results are reported and funds researchers who don’t file results

STAT News

National Institutes of Health failed to ensure that results of roughly half of clinical trials funded by the agency — both those conducted by its own scientists and outside researchers — were reported to a federal database during a recent two-year period, a new government review has found.

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Trial backs Lilly’s Olumiant plus remdesivir as combo COVID-19 therapy

pharmaphorum

Adding Eli Lilly’s rheumatoid arthritis drug Olumiant (baricitinib) and Gilead Sciences’ remdesivir reduces recovery time in COVID-19 patients compared to remdesivir alone, says a new trial. ACTT-2 used a 4mg dose of the drug, which wasn’t approved by the FDA on safety grounds.

Trials 111
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Why do Funding and Legal Structure Matter in Decentralized Clinical Trials?

Advarra

Designing a DCT comes with certain challenges of course, particularly when proposing to utilize outside groups or locations for the trial. Funding, sponsorship, tasks to be conducted, and the legal structures of entities may impact sites and the study overall. Why do Funding and Sponsorship Matter?

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New Hope Against Diseases Marked by Progressive Scarring of Lung Tissue

The Pharma Data

Steven Nathan, senior researcher on the new trial. There are, however, drugs for another form of pulmonary hypertension, known as pulmonary arterial hypertension. Over 16 weeks, patients randomly assigned to use the drug were able to improve their performance on a six-minute treadmill walk.

Doctors 52
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Economist Impact: World Cancer Series – pharmaphorum in attendance, day one (part ii)

pharmaphorum

Elliott informed those in attendance that for the next five years, with about £5 billion in funding for pipelines across a network of research and institute centres in clinical trials, that the aim is for everyone to live a life free of cancer. And in the UK over 30% of clinical trials funded has one European partner at least.

Nurses 87
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£2 million secured to fuel expansion in early phase clinical trials  

Drug Discovery World

Integrated drug formulation and clinical trials company, BDD Clinical Trials, has secured a further round of investment for £2M to aid the company’s expansion in response to growing demand for both its patented drug delivery technology and specialist clinical trial services.