Thu.Dec 24, 2020

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The best to all

World of DTC Marketing

This year I passed 750,000 readers and I could not be more thrilled. I know you love the industry as much as I do and that there is much work still to be done. May you holiday season be filled with great memories. The post The best to all appeared first on World of DTC Marketing.com.

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UK prepares for decision on AZ/Oxford vaccine as COVID cases soar

pharmaphorum

The UK’s COVID-19 vaccination programme could get a speed boost, with the country’s drugs regulator expected to make a decision on a shot from Oxford University/AstraZeneca in the next few days. If the vaccine becomes available the UK will be able to step up its vaccination programme as large swathes of the country face draconian “Tier 4” restrictions due to the emergence of as more infectious variant.

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Modeling can help balance economy, health during pandemic

Scienmag

Nearly 300,000 deaths could be averted, depending on how severe isolation measures become Credit: Washington University in St. Louis This summer, when bars and restaurants and stores began to reopen across the United States, people headed out despite the continuing threat of COVID-19. As a result, many areas, including the St. Louis region, saw increases […].

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5 ways digital health, and digital pharma, changed in 2020

pharmaphorum

Reviewing 2019’s key digital health stories last year I suggested that, while big strides continued to be made, any definitive ‘coming of age’ moment for the sector was unlikely. But that was before the first reports emerged of a highly contagious coronavirus and 2020 will be forever associated with COVID-19 and the global devastation and disruption it has wrought.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Kobe University and Sysmex conducted clinical evaluation of the ELISPOT method: A new test for COVID

Scienmag

Report on T cell immunity to SARS-CoV-2 in the Japanese population Credit: Sysmex/Kobe University Kobe University (Location: Kobe, Japan; President: Hiroshi Takeda) and Sysmex Corporation (HQ: Kobe, Japan; Chairman and CEO: Hisashi Ietsugu) have been engaged in joint research on the ELISPOT method, a new blood test for identifying the novel coronavirus disease (COVID-19).

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NICE backs AZ’s Forxiga for heart failure

pharmaphorum

Just a few weeks after its EU approval for heart failure, AstraZeneca’s Forxiga has been backed by NICE for this use by the NHS in England and Wales. Forxiga (dapagliflozin) – originally developed as a type 2 diabetes drug – is the first SGLT2 inhibitor to be approved for the treatment of symptomatic chronic heart failure with reduced ejection fraction (HFrEF) in adults with and without diabetes.

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AI-designed serotonin tracker could help develop neurology drugs

pharmaphorum

A serotonin sensor designed using Artificial Intelligence (AI) could help scientists study sleep and mental health and potentially find new neurology drugs. The US National Institutes of Health said that the research it had co-funded used AI to transform a bacterial protein into a new research tool. It is hoped that the protein, which “catches” serotonin molecules and allows them to be tracked, could detect subtle, real-time changes in serotonin levels during sleep, fear and social interactions.

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Help Me - I want to be a biostatistician!

ECRG Media's Clinical Research Podcast

I Want To Be a Biostatistician - Help Me Don't forget to Subscribe for new content! Subscribe: [link] Call or Text: 910-502-3732 Email: eliteclinicalgroup@gmail.com Podcast: [link] Steemit: [link] Advertise: eliteclinicalgroup@gmail.com Watch: » Industry News: [link] » All Videos: [link] » Interview Recaps: [link] » Glassdoor Reviews: [link] We do: » Insider Interviews » Resume Reviews » Question and Answer » Discuss all things Clinical Research » News and Product Reviews » Education Send in a v

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Top 10 Most Promising Drugs In The Amyotrophic Lateral Sclerosis Treatment Landscape

Delveinsight

Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig’s disease, is a group of rare neurological diseases that mainly involve the nerve cells (neurons), responsible for controlling voluntary muscle movement. The disease progresses over 3–5 years, making voluntary movements of arms and legs impossible. It is the most common form of motor neuron disease in adults.

Drugs 52
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Help Me - I want to be a biostatistician!

ECRG Media's Clinical Research Podcast

I Want To Be a Biostatistician - Help Me. Don't forget to Subscribe for new content! Subscribe: [link] Call or Text: 910-502-3732 Email: eliteclinicalgroup@gmail.com Podcast: [link] Steemit: [link] Advertise: eliteclinicalgroup@gmail.com Watch: » Industry News: [link] » All Videos: [link] » Interview Recaps: [link] » Glassdoor Reviews: [link] We do: » Insider Interviews » Resume Reviews » Question and Answer » Discuss all things Clinical Research » News and Product Reviews » Education.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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New patent expiration for Sanofi Aventis drug ALLEGRA-D 24 HOUR ALLERGY AND CONGESTION

Drug Patent Watch

Annual Drug Patent Expirations for ALLEGRA-D+24+HOUR+ALLERGY+AND+CONGESTION Allegra-d 24 Hour Allergy And Congestion is a drug marketed by Sanofi Aventis Us and is included in one NDA. It is available from…. The post New patent expiration for Sanofi Aventis drug ALLEGRA-D 24 HOUR ALLERGY AND CONGESTION appeared first on DrugPatentWatch - Make Better Decisions.

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Popular Blood Pressure Meds Won’t Up COVID Risk: Study

The Pharma Data

THURSDAY, Dec. 24, 2020 — Two widely used types of blood pressure drugs aren’t tied to an increased risk of COVID-19 infection or complications, according to a new study. In the early stages of the global pandemic, it was noted that people with high blood pressure had worse COVID-19 outcomes, and there was concern that angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blocker (ARB) blood pressure medications might be a factor.

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New Jersey Commission on Brain Injury Research funds Kessler Foundation study in children

Scienmag

Dr. Lengenfelder of Kessler Foundation will test new treatment for emotional processing deficits in children with traumatic brain injury Credit: Kessler Foundation/Jody Banks East Hanover, N.J. December 24, 2020 – Jean Lengenfelder, PhD, of Kessler Foundation, received a two-year $168,001 grant from the New Jersey Commission on Brain Injury Research to study the impact of […].

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Caring for Elderly Loved Ones During a Holiday Lockdown

The Pharma Data

THURSDAY, Dec. 24, 2020 — While everyone is dealing with the impact of the COVID-19 pandemic, older adults may feel the loss of holiday traditions the most. It is possible to make this season feel joyful, even with all the changes. It’s also a good time to check on their health and boost their mood, even from afar. “As much as you love the older adults in your life, now is not the time to gather with them, especially if you’re not in their bubble,” said Dr.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Human-made landscape promotes coexistence of two normally separated Andean warblers

Scienmag

Two Andean warbler species that typically occur at different elevations and hunt by tricking insects to escape can co-occur at the same elevation due to fragmentation of tropical montane forests caused by human agricultural practices Credit: photo by Jacek Nowakowski, the coauthor of the original paper at www.nature.com/articles/s41598-020-78804-2 In the mountains across the world, different […].

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As Testing Costs Rise, Neurology Patients May Skip Screening

The Pharma Data

THURSDAY, Dec. 24, 2020 — Rising out-of-pocket costs for neurological tests could lead many Americans to forgo them, researchers warn. Their study, published online Dec. 23 in the journal Neurology, analyzed neurology care costs for more than 3.7 million people in a large private insurance claims database. They found that average, inflation-adjusted out-of-pocket costs for diagnostic tests rose by as much as 190% over the study period.

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Astrocytes eat connections to maintain plasticity in adult brains

Scienmag

Credit: KAIST Developing brains constantly sprout new neuronal connections called synapses as they learn and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while connections deemed unnecessary are pruned away. Adult brains undergo similar pruning, but it was unclear how or why […].

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Even Winter Carries Skin Cancer Risks for College Students

The Pharma Data

THURSDAY, Dec. 24, 2020 – Researchers from two universities in Utah have a warning for students planning to hit the slopes or play in the snow without sunscreen: You could greatly increase your risk of skin cancer. A survey of students by Brigham Young University College of Nursing in Provo found that only 9% use sunscreen. They also found students’ use of tanning beds surges in winter, especially among men.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Eavesdropping on the pH levels inside the brain

Scienmag

Credit: Tohoku University Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures. In our brain, over billions of dedicated workers –neurons and glial cells –form complex and efficient networks that constantly communicate with each other via subtle chemical signals […].

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Amgen hands off leprosy, TB candidate to Australian non-profit

pharmaphorum

Amgen has decided that a drug for leprosy and tuberculosis it inherited as part of its acquisition of Celgene’s psoriasis blockbuster Otezla last year would fare better in the hands of a non-profit company, dedicated to bringing affordable medicines to poorer countries. AMG 634 – a PDE4 inhibitor being investigated for TB and leprosy complication erythema nodosum leprosum (ENL) – is being licensed to Australia’s Medicines Development for Global Health (MDGH), with Amgen surrendering all rights t

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International research team calls for ‘glocal’ approach to help mitigate flooding damage

Scienmag

Credit: Advances in Atmopheric Sciences Large-scale global forecasting and on-the-ground observations need to meld into one system to better predict and prevent wide-spread flooding disasters, according to an international research team who published a short view in Advances in Atmospheric Sciences on Dec. 23. “A ‘glocal’ — global to local — hydrometeorological solution for floods […].

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BMS calls time on brain cancer trial as Opdivo misses second target

pharmaphorum

Bristol Myers-Squibb has put out another downbeat “update” announcement about its immunotherapy Opdivo in an aggressive form of brain cancer, saying that it looks unlikely to produce a survival benefit in the disease. BMS said an independent committee had reviewed data from the phase 3 CheckMate-548 trial in newly diagnosed MGMT-methylated glioblastoma multiforme and concluded that it would be unlikely to meet its primary overall survival (OS) goal.

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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Protein tells developing cells to stick together

Scienmag

Credit: Tohoku University Tohoku University scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development. How tightly cells clump together, known as cell adhesion, appears to be enabled by a protein better known for its role in the immune system. The findings were detailed […].

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A Leading Softgel Encapsulation Machine Supplier Offering Automatic Softgel Manufacturing Equipment

The Pharma Data

WENZHOU, CHINA, December 24, 2020 /24-7PressRelease/ — Joysun Mech-Tech is a professional supplier and manufacturer for the softgel production machine, we offer softgel manufacturing production line which includes softgel machines , tumble dryers, gelatin melting tanks, medication tanks, transfer tanks, coloring machines, drying trays, softgel tooling.

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NIH awards $107M for COVID-19 testing tech; GSK secures rights; Roche’s bispecific matches Eylea; Research Updates in Leukemia, solid tumors

Delveinsight

NIH awards USD 107 Million for radical COVID-19 testing tech. The National Institutes of Health (NIH) awarded over USD 107 million for radical approaches to testing for COVID-19 and tracing the spread of the disease, including cutting-edge technologies, which could make daily coronavirus testing less interfering. dThis comprises nontraditional and repurposed technologies to address the prevailing gaps in the current nationwide surveillance effort and methods disposed against future outbreaks of

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Bonaventure Equity Announces Investment in Nalu Bio

The Pharma Data

“In short, they [Nalu Bio] are in it for the right reasons and are raising the bar for companies operating in the space of the cannabis economy,” said Ross O’Brien. WEST PALM BEACH, FL, December 24, 2020 /24-7PressRelease/ — BVE Select Fund, LLC, a Bonaventure Equity managed venture investor, is pleased to announce its investment in Nalu Bio, a biopharmaceutical firm focused on designing pure, science-backed, scalable cannabinoids for the retail and pharmaceutical mar

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Early mammal with remarkably precise bite

Scienmag

Researchers investigate teeth of a small carnivorous mammal that are almost 150 million years old Credit: © Thomas Martin, Kai R. K. Jäger / University of Bonn Paleontologists at the University of Bonn (Germany) have succeeded in reconstructing the chewing motion of an early mammal that lived almost 150 million years ago. This showed that […].

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Keto Vip Reviews-Does Keto Vip Work: Product Review By Voicendo

BioTech 365

Keto Vip Reviews-Does Keto Vip Work: Product Review By Voicendo Keto Vip Reviews-Does Keto Vip Work: Product Review By Voicendo Having Some Question in Your Mind About Keto Vip?

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COVID-19 severity affected by proportion of antibodies targeting crucial viral protein

Scienmag

COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study by researchers at Stanford Medicine. The findings identify new links between the course of the disease and a patient’s immune response. […].

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New tentative approval for Breckenridge drug asenapine maleate

Drug Patent Watch

Asenapine maleate is the generic ingredient in one branded drug marketed by Allergan and is included in one NDA. There are three patents protecting this compound. Drug patent litigation for…. The post New tentative approval for Breckenridge drug asenapine maleate appeared first on DrugPatentWatch - Make Better Decisions.

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.