Thu.Mar 03, 2022

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Biogen, struggling to sell Alzheimer's drug, begins layoffs to save money

Bio Pharma Dive

Biogen confirmed that some of its U.S. employees have been informed their roles are being eliminated. It's unclear, though, the magnitude of the layoffs or which departments are most affected.

Drugs 291
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More bad research on pharma websites

World of DTC Marketing

Press Ganey recently asked1 1,000+ healthcare consumers about their digital behaviors, but unfortunately, their findings mean little to emarketers working within the industry. They are somewhat embarrassing. So let’s look at some of the top insights from the report, along with my snide comments: Consumers turn to pharma sites for reliable information: In the age of empowered consumers, access to reliable healthcare information has never been more demand.

Research 143
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Roche, nearing major trial readouts, starts new Alzheimer's drug study

Bio Pharma Dive

As Aduhelm sputters on the market, Roche aims to prove its experimental medicine can work better. A large, multi-year trial is part of that bet.

Trials 307
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Stevenage Bioscience Catalyst launches accelerator program for biotech start-ups

BioPharma Reporter

Stevenage Bioscience Catalyst (SBC) has launched an accelerator program for biotech start-ups focusing on data-enabled drug discovery, genomics and advanced therapies: aiming to give such companies the skills they need to get potential new drugs and therapies to market more quickly.

Genome 111
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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Amid biotech downturn, Atlas raises $450M to build new drug startups

Bio Pharma Dive

While a stock market slide has made IPOs difficult for young biotech companies, venture capital firms like Atlas are still reloading with new cash to create and invest in new drugmakers.

Drugs 266
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Which Countries Had the Most Food Industry M&A Deals in 2021?

XTalks

In the perfect food industry merger and acquisition (M&A) deal, both parties come out ahead. Last year saw several examples of both buyers and sellers in the food industry walking away with something to position them for more stable, sustainable growth. But which countries had the most food industry M&A deals in 2021? US Leads Food Industry M&A Deals.

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Stage set for Jardiance to become universal heart failure drug

pharmaphorum

Boehringer Ingelheim and Eli Lilly have published data for their SGLT2 inhibitor Jardiance in acute heart failure, setting them on course to position the drug across the spectrum of patients with the condition. The results of the EMPULSE trial showed that adults hospitalised for acute heart failure were 36% more likely to see an improvement on clinical measures – including all-cause mortality, frequency of heart failure events, time to first heart failure event, and symptoms – in the first 90 da

Drugs 98
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Wuxi STA site passes EMA drug product pre-approval inspection

BioPharma Reporter

WuXi STA says its drug product facility in Wuxi City, China has successfully passed its first pre-approval inspection (PAI) and received the GMP compliance certificate from the European Medicines Agency (EMA).

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Partake Foods Allergen-Friendly Snacks + Imagindairy Cow-Free Milk – Xtalks Food Podcast Ep. 50

XTalks

Food allergies are becoming more and more common, but that doesn’t mean those with allergies can’t enjoy a sweet treat. In this episode of the Xtalks Food Podcast, Sydney talks about Partake Foods, an allergen-friendly, better-for-you snack brand that offers cookies, baking mixes and other products in which everyone can partake. However, the brand sells more than just sweet treats.

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First RSV vaccine trial for infants offers significant results

Pharma Times

The phase 3 MELODY study reveals that nirsevimab vaccine reduces lower respiratory tract infections

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Sanofi forges $30m alliance with digital health firm DarioHealth

pharmaphorum

DarioHealth has beefed up its sales and marketing channels as well as its range of digital health products thanks to a $30 million strategic alliance with drugmaker Sanofi. Under the terms of the five-year deal, Sanofi digital health apps will be integrated into Dario’s platform and Sanofi’s sales muscle will be deployed to market the combined offering.

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Previously untreatable lung cancer patients offered new therapy

Pharma Times

NICE document recommends Amgen’s Lumykras (sotorasib) to treat non-small-cell lung cancer

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Robot “bugs” that can go just about anywhere

Scienmag

These ancient creatures can squeeze through the tiniest cracks, fit snugly into tight spaces and survive in harsh environments: There aren’t many spaces that are off-limits to an insect. Credit: The Shankar Research Group These ancient creatures can squeeze through the tiniest cracks, fit snugly into tight spaces and survive in harsh environments: There aren’t […].

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Moderna creates Enterprise Solutions Hub in Atlanta

BioPharma Reporter

mRNA pioneer Moderna will establish an Enterprise Solutions Hub in Atlanta: which will host finance, human resources, procurement and digital functions.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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What explains our lower back pain? Anthropologists turn to Neandertals for answers

Scienmag

Examining the spines of Neandertals, an extinct human relative, may explain back-related ailments experienced by humans today, a team of anthropologists has concluded in a new comparative study. Credit: Image courtesy of Scott Williams, NYU’s Department of Anthropology. Examining the spines of Neandertals, an extinct human relative, may explain back-related ailments experienced by humans today, […].

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IDT Biologika and Exothera collaborate to scale-up viral vaccine manufacturing

BioPharma Reporter

IDT Biologika and Exothera S.A. are working together to develop a large-scale manufacturing process for viral vector-based vaccines.

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Showing different types of COVID-19 data can directly influence behaviour during the pandemic

Scienmag

A new U of T Scarborough study finds that showing COVID-19 data in a certain way can influence how seriously people view the pandemic, which in turn can impact their behaviour. The study looked at two commonly used types of data: stock (the total case counts since the pandemic started) and flow (the number of […].

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Touchlight and Versameb in enzymatic DNA development and manufacturing deal

BioPharma Reporter

UK headquartered Touchlight has agreed a development and manufacturing pipeline agreement with Swiss company, Versameb.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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New species of stegosaur is oldest discovered in Asia, and possibly the world

Scienmag

Relatively small, but fearsome-looking stegosaur measured about 2.8 metres (9 feet) from nose to tail—but scientists can’t tell whether the remains are those of an adult or juvenile. Credit: Credit Banana Art Studio Relatively small, but fearsome-looking stegosaur measured about 2.8 metres (9 feet) from nose to tail—but scientists can’t tell whether the remains are […].

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Preparing industry leaders for digital transformation

pharmaphorum

Digital transformation is taking root in every major industry, and healthcare and life sciences are no exception. In fact, digital technology may prove to be more transformative in the healthcare sphere than in other industries as it forces us to rethink core concepts like episodes of care and small molecules in favour of emerging models and tools like ongoing virtual care, digital medicines and therapeutics.

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Magnetic excitations could provide information transfer without heat loss

Scienmag

Just as electrons flow through an electrical conductor, magnetic excitations can travel through certain materials. Such excitations, known in physics as “magnons” in analogy to the electron, could transport information much more easily than electrical conductors. An international research team has now made an important discovery on the road to such components, which could be […].

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Blood pressure medication shows benefits treating Type 1 diabetes

The Pharma Data

Use of the drug verapamil to treat Type 1 diabetes continues to show benefits lasting at least two years, researchers report in the journal Nature Communications. Patients taking the oral blood pressure medication not only required less daily insulin two years after first diagnosis of the disease, but also showed evidence of surprising immunomodulatory benefits.

Insulin 52
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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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The future of data storage is double-helical, research indicates

Scienmag

Imagine Bach’s “Cello Suite No. 1” played on a strand of DNA. Credit: The Beckman Institute for Advanced Science and Technology at the University of Illinois Urbana-Champaign. Imagine Bach’s “Cello Suite No. 1” played on a strand of DNA. This scenario is not as impossible as it seems. Too small to withstand a rhythmic strum […].

DNA 86
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New patent for Heron Theraps drug ZYNRELEF KIT

Drug Patent Watch

Annual Drug Patent Expirations for ZYNRELEF+KIT Zynrelef Kit is a drug marketed by Heron Theraps Inc and is included in one NDA. It is available from one supplier. There are…. The post New patent for Heron Theraps drug ZYNRELEF KIT appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
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Temperature variation could help new touchscreen technology simulate virtual shapes

Scienmag

High-fidelity touch has the potential to significantly expand the scope of what we expect from computing devices, making new remote sensory experiences possible. The research on these advancements, led by a pair of researchers from the J. Mike Walker ’66 Department of Mechanical Engineering at Texas A&M University, could help touchscreens simulate virtual shapes.

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New patent for MIRUM drug LIVMARLI

Drug Patent Watch

Annual Drug Patent Expirations for LIVMARLI Livmarli is a drug marketed by Mirum and is included in one NDA. The generic ingredient in LIVMARLI is maralixibat chloride. Additional details are…. The post New patent for MIRUM drug LIVMARLI appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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A role for Chinese funders in fostering research integrity reform

Scienmag

In a Policy Forum, Li Tang argues that China’s science funding system needs to play a larger role in curbing scientific misconduct and in improving Chinese research integrity. The Chinese science grant system, which is largely subsidized by government funding, plays an important role in supporting a rapidly growing research and development enterprise well situated […].

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Next Generation Complement Therapeutics: Potential Life-Changing Therapies for Multiple Rare Disorders

Roots Analysis

Since the approval of Soliris® in 2007, an anti-C5 antibody, the field of complement drug discovery has gained significant attention. Currently, nine complement therapeutics are commercially available, while around 190 molecules are under development for various disease indications. Some of the complement therapeutics, namely Berinert®, Cinryze®, ORLADEYO®, Ruconest® and TAKHZYRO® were approved for the treatment of hereditary angioedema, by the US FDA and the EMA.

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Seeing is believing when it comes to health risk and behavior change

Scienmag

They say a picture can convey a thousand words, and researchers have found that using medical imaging technologies that can visualize health may discourage risk-related behaviors more than non-visual information. The meta-analysis, publishing March 3rd in the open access journal PLOS Medicine, finds that when individuals undergo an imaging procedure and are shown visual personalized […].

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Fishawack Health acquires HEOR consultancy PAI

pharmaphorum

March 3, 2022, London, UK — Fishawack Health (FH), a leading commercialization partner for biopharmaceutical, medical technology, and wellness companies, today welcomes the US-based health economics and outcomes research (HEOR) consultancy Policy Analysis Inc. (PAI) as part of its expanding Value, Evidence, and Access (VEA) capability. With the addition of PAI, FH now has one of the largest and fastest-growing teams dedicated to value, evidence, and access, all of which are critical to the comme

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.