Fri.Mar 07, 2025

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Calcium channel inhibition promotes cardiac regeneration, offering hope for heart failure treatment

Medical Xpress

Researchers report a discovery in cardiac regeneration that offers new hope for the treatment of ischemic heart failure. Published in npj Regenerative Medicine, the study reveals a novel approach to promoting cardiomyocyte proliferation. The researchers are from the Michael E. DeBakey Department of Surgery at Baylor College of Medicine, the QIMR Berghofer Medical Research Institute in Brisbane, Australia, and collaborating institutions.

Medicine 129
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Roche launches new Boston center; NIH centralizes peer review

Bio Pharma Dive

The Swiss pharma will base cardiometabolic drug research at the new Allston site. Elsewhere, AskBio advanced a gene therapy and Pfizer hired a scientist well versed in GLP-1 science.

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Bridging the Gap in Patient Support: How GoodRx is Revolutionizing Access to Specialty Meds

Drug Channels

Todays guest post is from Divya Iyer, SVP Go-to-Market (GTM) Strategy at GoodRx. Divya argues that patient support programs (PSPs) struggle with awareness and accessibility, preventing patients from fully benefiting from the financial and educational resources available to them. Divya discusses how integrating digital solutions from GoodRx can enhance engagement, streamline access to therapy, and improve patient outcomes.

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Nimbus swaps CEOs and turns to new leader for ‘next chapter’

Bio Pharma Dive

CBO Abbas Kazimi will replace longtime CEO Jeb Keiper as part of a planned leadership transition at the unorthodox drug startup.

Drugs 173
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Running Decentralized Trials at Scale: Planning for Success

There’s been a rapid shift towards decentralization in clinical trials & it’s clear why. The potential for reaching a larger pool of recruits is possible when sponsors can bring more trial activities to the patient. Tele visits, digital consent, new monitoring sensors, & direct-to-patient supply are virtual tools that existed before the pandemic, but now there’s swift adoption of these methods because they’ve been proven to help launch & complete trials more effectively.

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UK’s pricing watchdog rejects Alzheimer treatments for the second time

Pharmaceutical Technology

NICE previously rejected Leqembi and Kisunla for NHS coverage in August and October 2024, respectively.

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Walgreens to be acquired in $10B take-private deal

Bio Pharma Dive

The struggling retail pharmacy chain entered an agreement to be purchased by private equity firm Sycamore Partners, which could end its nearly 100-year run as a public company.

Pharmacy 147

More Trending

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Redefining Loyalty: The Role of Decentralized Healthcare and Data Ownership

Intouch Solutions

This POV explores how decentralized healthcare models and data ownership are transforming patient loyalty, and highlights strategies to foster loyalty in this new landscape. Patient empowerment, patient-centric, choices, responsiveness, flexibility, competition and innovation are just a few of the positive attributes of decentralized healthcare delivery systems such as those in the United States.

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FDA ODD given to Plus Therapeutics’ injectable radiotherapy

Pharmaceutical Technology

The FDA has granted orphan drug designation to Plus Therapeutics injectable radiotherapy, Rhenium (186Re) Obisbemeda.

Drugs 147
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J&J scraps depression testing for potential blockbuster drug

Bio Pharma Dive

Analysts say the decision is a “big blow” to a once-promising class of brain therapies that include’s J&J’s aticaprant and a drug from Neumora.

Drugs 113
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The trillion-dollar opportunity in women’s health

Pharmaceutical Technology

Closing the gap in health interventions between men and women could add $1tn to the global GDP, unlocking seven additional years for women.

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2022 Research: The Rapid Rise of Ocean Freight Visibility

A research study conducted by The Journal of Commerce and FourKites surveyed hundreds of international shippers, exploring how their usage of global supply chain visibility technology has evolved since the onset of global disruptions caused by COVID-19. For international shippers, ocean freight visibility has evolved from optional to essential and satisfaction with visibility varies greatly depending on how it is obtained and delivered.

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Paul Evans Joins the Leaders & Legends Podcast With Patty Leuchten

Velocity Clinical Research

Paul Evans sat down with Patricia Leuchten on the Leaders & Legends podcast, where they discussed the state of research sites and the broader industry. Listen now to hear Paul’s thoughts on: The evolution of clinical research sites and whats ahead for the industry. Challenges in patient recruitment and the role of site-based technology. His journey from growing up in Swansea, Wales, to leading the worlds largest research site organization.

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Astellas and Yaskawa form JV for cell therapy product manufacture

Pharmaceutical Technology

Astellas Pharma and Yaskawa have agreed to form a JV that will focus on developing a cell therapy product manufacturing platform.

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Biogen, Apple study finds smart devices can track cognition

pharmaphorum

An observational study backed by Biogen has suggested that Apple smartphones and watches may be able to spot the signs of mild cognitive impairment

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Understanding the rules on HPAPI containment in high potent manufacturing

Pharmaceutical Technology

How to ensure safety and quality in pharmaceutical facilities when using HPAPIs in drug development. Read more here.

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An Innovative & Creative Problem Solver Approach to Selling in the Medical Device Space

Speaker: Steve Goldstein, Sales Leader

Are you currently in sales, or involved in a business that depends on strong sales results? What about the extremely competitive world of medical device sales? What are some of the top challenges your customers face and how do you approach understanding what’s most important to them? Join Steve Goldstein, Sales Success Coach, Motivational Speaker and Medical Device Sales Leader from Gold Selling LLC., to discover critical strategies and approaches you can take to engage your customers, achieve g

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Do we see the same red? New qualia structure paradigm measures shared sensory experiences

Medical Xpress

A team of psychologists, bioengineers and neurologists from The University of Tokyo and Monash University in Australia has tested the possibility of using a qualia structure paradigm to understand whether sensory experiences are intersubjectively equivalent. Their paper is published in the journal iScience.

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Tumour-on-chip model could help discover pancreatic cancer therapies

Pharmaceutical Technology

A tumour-on-chip model on PDAC has been developed to allow insights into interactions between tumour cells and potential treatments.

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Ammonia buildup kills liver cells but can be prevented using existing drug

Medical Xpress

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice led by researchers from UCL.

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Neurotech's cell therapy gets FDA nod for eye disorder MacTel

pharmaphorum

Neurotech Pharma's cell therapy Encelto has become the first FDA-approved treatment for idiopathic macular telangiectasia type 2

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Fluoride in drinking water associated with impaired childhood cognition, study of rural Bangladesh suggests

Medical Xpress

Elevated concentrations of fluoride can occur in well water, and in some countries, it is added to drinking water to counteract caries in the population. A study from Karolinska Institutet now supports a few previous studies indicating that exposure to fluoride during the fetal stage or early childhood may impair cognition in children. The study is published in the journal Environmental Health Perspectives.

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One of J&J's blockbuster depression hopes has flamed out

pharmaphorum

Johnson & Johnson has halted the development of aticaprant as a treatment for major depressive disorder, blowing a hole in its late-stage pipeline

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Genome-edited stem cells reveal new hope for obesity treatment without muscle loss

Medical Xpress

In a study published in Nature Communications, researchers at the Beijing Institute of Stem Cells and Regeneration (BISCRM) and the Institute of Zoology (IOZ) have cracked the code of the notorious FTO gene, reconciling its dual role in obesity and muscle growth. The revelation could improve obesity and diabetes treatments, potentially offering an alternative to popular GLP-1 receptor agonists that may cause undesirable muscle wasting.

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Exosomes in Cosmetics

Pharma Tutor

Exosomes in Cosmetics admin Fri, 03/07/2025 - 16:08 Vinay Kumar Singh. Head-Formulation Kumar Organic Products Research Centre Pvt. Ltd., Bengaluru Email : formulation_krc@kopresearchcentre.

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Incidents of children being poisoned by fentanyl have risen in the US, national data show

Medical Xpress

Incidents of children in the US being poisoned by the synthetic opioid fentanyl "increased and became more severe," a new study reveals.

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Streamlining Prescription Processes

Pharmaceutical Commerce

In the final part of his video interview with Pharma Commerce Editor Nicholas Saraceno, Tom Dorsett, CEO, RazorMetrics, describes how the software companys solution can help deliver better patient outcomes and substantial savings for healthcare plans, employers, and members alike.

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Inpatient dialysis initiation higher for patients with chronic kidney disease and heart failure

Medical Xpress

Patients with chronic kidney disease (CKD) and heart failure have higher rates of inpatient dialysis initiation than those without heart failure, according to a study published online Feb. 18 in Mayo Clinic Proceedings.

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Reimagining women's health in the 21st century

pharmaphorum

Explore how data is revolutionising women's health in the 21st century, transforming the way we understand and address women's unique health needs. Discover the latest advancements and innovations in this field.

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How hot does a firefighter get? Simulated smoke dive reveals core temperatures

Medical Xpress

The heat hits you like a ton of bricks. Maybe flames do too. Smoke is everywhere, it's hard to see anything. But you have to go in. More than likely, you probably have to lift, pull or carry heavy objects.

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Pharma Pulse 3/7/25: Shaping Trust Through Design, New Interest in Direct Contracting & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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Data-driven engagement: How big data is revolutionising patient experiences

pharmaphorum

Discover how big data is revolutionising patient experiences in healthcare through data-driven engagement strategies. Learn how innovative technologies are enhancing patient care and outcomes.

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Bladder wall thickness reflects severity of bladder inflammatory conditions

Medical Xpress

For patients with interstitial cystitis/bladder pain syndrome (IC/BPS), bladder wall thickness (BWT) on computed tomography (CT) scans reflects the severity of bladder inflammatory conditions, according to a study published online Feb. 4 in the World Journal of Urology.

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Denali's ALS programme suffers another setback

pharmaphorum

Prospects for Denali Therapeutics' experimental medicine for amyotrophic lateral sclerosis have taken another tumble.

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Gum health: A key indicator of women's overall well-being

Medical Xpress

"Many women don't realize the connection between hormonal changes and their gum health," says Nicola West, secretary general of the European Federation of Periodontology. "Throughout different stages of a woman's life, such as puberty, pregnancy and menopause, hormone fluctuations can make gums more vulnerable to disease, making oral care ever more essential for overall health.

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Taking Charge on National Kidney Month 2025 and World Kidney Day 2025: Are Your Kidneys OK?

XTalks

Every March, communities across the country come together for National Kidney Month 2025 a time dedicated to raising awareness about kidney disease and empowering individuals to take charge of their health. Complementing this national focus is World Kidney Day 2025, celebrated on March 13, a global campaign with origins rooted in international efforts to elevate kidney health awareness and foster cross-border collaboration.

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Measles reported in 9 states: Here's what you need to know

Medical Xpress

More than 160 measles cases have been reported across nine states this year, with one death and more than 30 patients needing hospitalization, according to a Centers for Disease Control and Prevention tracker.

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