Fri.Apr 25, 2025

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Biohaven stock slides on withdrawal of European marketing application

Bio Pharma Dive

The drug, being developed for a rare genetic disorder and currently under review in the U.S., is seen by some investors as critical to Biohaven’s future.

Genetics 272
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Insights and Inspirations On and About the Clinical Research Workforce

ACRP blog

At the latest meeting of the Association of Clinical Research Professionals (ACRP)-led Partners Advancing the Clinical Research Workforce (PACRW) consortium, the focus for these extraordinary times in human subjects research was on what levers need to be pulled by the consortiums members to bend the curve toward a better future for stakeholders in what is often an under-recognized and under-resourced segment of the larger healthcare workforce.

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FDA free to pursue semaglutide compounders after latest court ruling

Pharmaceutical Technology

Despite the decision being a win for Novo Nordisk, the compounded drugs sector is far too complex for this to be a final resolution.

Drugs 189
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Caribou, in reversal, scraps autoimmune cell therapy and cuts staff

Bio Pharma Dive

The CRISPR company is laying off about a third of its employees and stopping work on an experimental lupus treatment in a bid to focus resources on a pair of cancer cell therapies.

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How to Turn “Check-the-Box” Compliance Trainings Into Real Learning

Speaker: Brian Richardson, Brian Richardson, Founder and CEO of Richardson Consulting Group

Let’s face it—most ethics and compliance trainings aren’t winning awards for engagement. But that doesn’t mean they can’t be effective, relevant, and maybe even enjoyable! Join expert Brian Richardson for a dynamic session on how to breathe new life into your ethics and compliance training programs. You’ll discover creative strategies to turn traditionally dry topics into meaningful learning experiences that resonate and drive real change.

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Delgocitinib Investigational Cream Outshines Standard Care in Chronic Hand Eczema Trial

XTalks

This week, LEO Pharma announced the publication of pivotal Phase III clinical trial results in The Lancet for its topical delgocitinib cream to treat severe chronic hand eczema (CHE). Results from the trial showed delgocitinib to have superior efficacy and safety over oral alitretinoin, the current standard of care for CHE. The DELTA FORCE trial is the first head-to-head Phase III study comparing a topical treatment with a systemic therapy for CHE.

Trials 66
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Gilead leans on HIV drugs as oncology sales slow

Bio Pharma Dive

The company is looking to the highly anticipated launch of a closely watched HIV medicine to offset weakening demand for Trodelvy and its cancer cell therapies.

Sales 170

More Trending

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Halozyme sues Merck; FDA blames cuts for Vanda delay

Bio Pharma Dive

Halozyme claims Merck infringed on patents in developing a subcutaneous form of Keytruda. Elsewhere, Vanda’s challenge to an FDA rejection dragged on, while Sanofi revealed an immune drug setback.

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Granite Bio secures $100m in funding for new antibodies

Pharmaceutical Technology

Granite Bio has secured $100m in funding for its new antibody treatments that target several autoimmune diseases.

Antibody 130
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Why our waistlines expand in middle age—aging stem cells shift into overdrive

Medical Xpress

It's no secret that our waistlines often expand in middle age, but the problem isn't strictly cosmetic. Belly fat accelerates aging and slows down metabolism, increasing our risk for developing diabetes, heart problems and other chronic diseases. Exactly how age transforms a six pack into a softer stomach, however, is murky.

Cosmetics 105
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Caribou cuts pipeline and workforce to focus on lead CAR-T programmes

Pharmaceutical Technology

Caribou is scaling back its operations, halting multiple programmes, and cutting staff to focus on two cancer programmes.

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Clinical Research White Paper – Enhancing Transparency & Efficiency Throughout the Trial Lifecycle

Enhancing Transparency & Efficiency Throughout the Trial Lifecycle for AI Readiness

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Acoramidis approved for heart condition treatment

Pharma Times

MHRA authorises drug for adults with rare heart muscle damage

Drugs 100
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EC grants orphan drug designation to Dyne Therapeutics’ DMD therapy

Pharmaceutical Technology

The EC has granted orphan drug designation to Dyne Therapeutics DYNE-251 for treating Duchenne muscular dystrophy (DMD).

Drugs 130
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Ozempic patient blinded by NAION sues Novo Nordisk

pharmaphorum

Ozempic patient blinded by NAION sues Novo Nordisk Jonah.

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Mosaic therapeutics expands pipeline with Astex deal

Pharma Times

Cambridge firm in-licenses two oncology programmes

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Can Your Organization Spot a Conflict Before It’s a Crisis?

Speaker: Amie Phillips Pablo, VP, Corporate Compliance & Privacy Officer at Novo Nordisk

In today’s complex healthcare environment, navigating third-party relationships has become even more challenging—whether it’s vendor relationships, employee activities, or patient-facing interactions. Left unmanaged, these conflicts can compromise trust, regulatory compliance, and even organizational reputation. So, how can healthcare teams stay ahead?

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Akeso PD-1 inhibitor cleared as Keytruda challenger advances

pharmaphorum

Akeso has bagged an FDA approval for its PD-1 inhibitor penpulimab and reported new data on highly-touted PD-1/VEGF bispecific ivonescimab.

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Serotonin system's hidden complexity may reshape understanding of day-to-day decision making

Medical Xpress

Our lives are filled with binary decisionschoices between one of two alternatives. But what's really happening inside our brains when we engage in this kind of decision making?

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Merck puts a price on its SpringWorks takeover bid

pharmaphorum

Merck KGaA has confirmed that talks to buy SpringWorks have advanced to the 'late-stage' and are revolving around an offer of around $47 per share

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Brain's immune response may set stage for childhood paralysis disorder

Medical Xpress

Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease, the brain appears to play a major role by over-activating the immune system, as shown by a recent study published in the Journal of Experimental Medicine.

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White Paper - A Roadmap to AI Data Readiness in R&D Labs

Download this comprehensive guide to AI and ML in the R&D Laboratory Setting.

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Fast-Tracking the Future

Pharmaceutical Commerce

Claire Riches highlights inefficiencies in the current drug approval process, while outlining the role of payers and insurers in shifting toward data-driven approval framework.

Drugs 69
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Study identifies how malaria can lead to childhood cancer

Medical Xpress

New data published in The Journal of Immunology has revealed the role of Plasmodium falciparum infection (malaria) in the development of Burkitt lymphoma (BL), the most common childhood cancer in equatorial Africa and New Guinea. BL has been associated with P. falciparum malaria since 1958, but the underlying mechanism of how it led to cancer had remained a mystery.

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AbbVie files fast-acting Botox successor in US

pharmaphorum

AbbVie is hoping to extend its range of neurotoxin-based pharma and cosmetic products with a short-acting successor to its blockbuster Botox brand.

Botox 66
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Novavax COVID vaccine moves closer to full FDA approval

Medical Xpress

Novavax's COVID-19 vaccine could soon receive full approval from the U.S. Food and Drug Administration (FDA), the company said Wednesday.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Granite Bio makes $100m debut, and other bio financings

pharmaphorum

Our round-up of recent biotech financings includes rounds for Granite Bio, Biolinq, Etiome, Grove Biopharma, and Synthetic Design Lab

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Survey reveals women may be experiencing perimenopause in their 40s

Medical Xpress

Six in 10 women believe they will hit menopause in their 40s, according to survey results released April 8 by The Ohio State University Wexner Medical Center in Columbus.

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Buyer’s remorse: The UK’s VPAG

pharmaphorum

Leela Barham takes stock of the debate surrounding the UKs current pricing and access deal that caps NHS spend on branded medicines, after a higher-than-expected payback rate for 2025.

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Will Moving Drug Production to the United States Help or Hurt Patients?

Pharmaceutical Commerce

In the third part of his video interview with Pharma Commerce Editor Nicholas Saraceno, Paul Levesque, CEO of Theratechnologies, explains what the mindset be for companies who are just starting the reshoring process.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Enhancing rare disease trials: eCOA technology’s impact on sickle cell research

pharmaphorum

Today digital innovationsmost notably electronic clinical outcome assessments (eCOAs)are reshaping clinical trial methodologies, particularly in the rare disease space.

Trials 52
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Radioiodine therapy found to improve relative survival rates of differentiated thyroid cancer patients

Medical Xpress

Differentiated thyroid cancer patients who receive radioiodine (RAI) treatment after surgery have increased relative survival rates compared to those who do not receive the treatment. According to new research published in the April issue of The Journal of Nuclear Medicine, the clear trend for a higher long-term survival rate is observed in subgroups of patients with low- and intermediate-risk disease, while there is special benefit in high-risk diseases.

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FDA approves Akeso’s monoclonal antibody for nasopharyngeal carcinoma

Pharmaceutical Technology

The FDA has granted approval to Akeso's differentiated programmed cell death protein 1 (PD-1) monoclonal antibody, penpulimab-kcqx,

Antibody 130
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What to know about processed and ultra-processed food

Medical Xpress

Take a stroll down the middle aisles of any American grocery store, and you'll be surrounded by rows of brightly colored packaged macaroni and cheese, instant soups and chips in all forms and flavorsall with long ingredient lists. These and other familiar favorites offer consumers a convenient, tasty and often affordable meal or snack.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model