Wed.Mar 02, 2022

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Gene editing biotechs face new uncertainty after CRISPR patent ruling

Bio Pharma Dive

A federal patent board ruled Broad Institute scientists were first to a key gene editing advance, weakening the patent position of Intellia and CRISPR Therapeutics, which hold licenses through the University of California.

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Doximity study on telehealth flawed

World of DTC Marketing

Over 73% of patients plan to continue using telemedicine platforms post-pandemic, according to Doximity’s second edition of its State of Telemedicine Repor t , which was released today. As part of the report, Doximity, the leading digital platform for U.S. medical professionals, analyzed the adoption of telemedicine across its physician user base from January 2020 through June 2021 and conducted a study of patients’ experiences with telemedicine during the same time frame.

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FDA sets back Karyopharm's bid to broaden use of cancer drug

Bio Pharma Dive

The biotech appeared poised to seek approval of its treatment, selinexor, in endometrial cancer. But regulators had a "differing" view of the data and requested another clinical trial.

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Aedesius Health and its lead biopharma company, AO BIO partner with Indegene for a comprehensive commercialization engagement

Pharma Mirror

MONTGOMERY, Ala. and PRINCETON, N.J. and LONDON and BANGALORE, India, Aedesius Health, a division of AedesiusOne Ltd, and its biopharmaceutical development incubator AO BIO, which is focused on developing and commercializing neglected and needed therapies, devices, and diagnostics, today announced a comprehensive commercialization partnership with Indegene, a technology-led healthcare solutions provider.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Sanofi partners with digital health company DarioHealth

Bio Pharma Dive

The deal with DarioHealth is one of several digital health investments by the French pharma company in recent years, although not all have panned out.

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Sterling Pharma Solutions Expands Global API Manufacturing Capabilities with Acquisition of Novartis Facility in Ringaskiddy, Ireland

Pharma Mirror

Sterling Pharma Solutions, a global contract development and manufacturing organisation, today announced that it had reached agreement with Novartis to acquire its Ringaskiddy campus (Novartis Ringaskiddy Limited), near Cork, Ireland. Financial details of the sale, which is expected to close in Q4, 2022, have not been disclosed. Under the terms of the agreement, Sterling will acquire the 111-acre site, which includes three active pharmaceutical ingredient (API) manufacturing buildings, as well a

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5 Social Security Benefits Facts You Might Not Know

Pharma Mirror

While most only really know the basics of Social Security, this administration is an insurance program that provides families and individuals with the necessary information and tools to obtain financial stability. However, claiming Social Security disability benefits can be time-consuming. Moreover, claims are sometimes rejected due to minor errors.

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Can psychedelics provide breakthrough in mental health?

pharmaphorum

There is a growing pipeline of psychedelic therapies and an expanding body of science to suggest that they may be able to provide an alternative to existing mental health treatments. Ben Hargreaves discovers why medical research in the area has shifted from being highly controversial to being backed by major pharma companies and venture capital. The image of psychedelic drugs within medical research is changing.

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Novartis’ Kesimpta trial provides positive results for MS patients

Pharma Times

MS patients given boost by results of study into Kesimpta – a self-administered treatment with potential to improve lives

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Gradual evolution is back: Darwinian theory of gradual process explained in new research

Scienmag

Abrupt shifts in the evolution of animals – short periods of time when an organism rapidly changes size or form – have long been a challenge for theorists including Darwin. Now a newly published research paper supports the idea that even these abrupt changes are underpinned by a gradual directional process of successive incremental changes, […].

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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New patent expiration for Noden Pharma drug TEKTURNA HCT

Drug Patent Watch

Annual Drug Patent Expirations for TEKTURNA+HCT Tekturna Hct is a drug marketed by Noden Pharma and is included in one NDA. It is available from one supplier. There are two…. The post New patent expiration for Noden Pharma drug TEKTURNA HCT appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 98
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“Closest black hole” system found to contain no black hole

Scienmag

In 2020 a team led by European Southern Observatory (ESO) astronomers reported the closest black hole to Earth, located just 1000 light-years away in the HR 6819 system. But the results of their study were contested by other researchers, including by an international team based at KU Leuven, Belgium. In a paper published today, these […].

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Clinical jobs increase as R&D and lab roles experience record growth

Pharma Times

The post-Brexit landscape has witnessed an exponential boom in life science careers

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THE LANCET: Social and economic effects of the COVID-19 pandemic threaten to reverse progress towards gender equality, new study reveals

Scienmag

Peer-reviewed / Observational and Modelling / People **Regional data is available—see notes to editors** First comprehensive report on gender disparities caused by indirect impacts of the COVID-19 pandemic, which analysed differences in vaccine hesitancy and uptake, healthcare services, economic and work-related concerns, education, and safety at home and in the community.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Healthware Group announces acquisition of Argon Global Healthcare network

pharmaphorum

Global health innovation and technology leader, Healthware Group , has announced the acquisition of Argon Global Healthcare, one of the largest international networks of independent healthcare agencies. The deal will see CEO and partner at Argon Global Healthcare Massimo Vergnano assume the role of senior associate partner, brand strategy at Healthware Group.

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Lasell University, UMass Lowell collaborate to diversify pipeline of special education teachers

Scienmag

NEWTON, Mass. – Lasell University and UMass Lowell today announced a joint venture designed to diversify the pipeline of students pursuing careers in special education and applied behavior analysis. Credit: Adrien Bisson for UMass Lowell NEWTON, Mass. – Lasell University and UMass Lowell today announced a joint venture designed to diversify the pipeline of students […].

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Biopharmaceutical Industry Soars in Drug R&D Amid COVID-19

Pharma Marketing Network

New findings from an IQVIA report show the biopharmaceutical industry is sparking with activity with an astounding 6,000 products in development and new geographical locations seeing the boom. While it was a concern that COVID-19 would slow down new ventures in the biopharmaceutical sector, the reality has been just the opposite. According to Murray Aitken, IQVIA’s Senior VP and Executive Director of the IQVIA Institute for Human Data Science, “the pandemic has accelerated biopharmac

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Joro spiders likely to spread beyond Georgia

Scienmag

If you live in Georgia, it’s hard not to notice the state’s latest resident. Credit: UGA/Submitted Photo If you live in Georgia, it’s hard not to notice the state’s latest resident. The bright yellow, blue-black and red spiders’ golden webs will be all over power lines, in trees around town and even on your front […].

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Ep. 19: Let’s Talk “TALK and Pharma” – Jennifer Ginest and Charles Benaiah, Founder of Watzan and ililli

Pharma Marketing Network

Tune in to this episode of the Pharma Marketing Podcast to hear a discussion with Charles Benaiah, Innovator, Founder and CEO of Watzan, Founder of ililli , and Jennifer Ginest, Digital Marketing Manager of PMN on audio and the possibilities of integrating it into your marketing strategy.

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Capturing the many facets of evolvability

Scienmag

All life evolves: microorganisms can become resistant to drugs, viruses evade our vaccines, and species may adapt to climate change. Even the ability to evolve can evolve. If we were to understand how this happens and which mechanisms play a role, it may be possible to predict evolution to some extent. This is why the […].

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Oral Protein / Peptide-based Drugs: Addressing Key Unmet Needs Across Disease Indications

Roots Analysis

Orally administrable protein / peptide-based therapeutics offer several advantages including, effective treatment of numerous clinical conditions and degenerative disorders. Interestingly, recent advances in this domain have led to the development of several treatment strategies that, according to developers, exhibit the necessary capabilities to overcome challenges posed by traditional oral protein formulations and peptide-based therapies.

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Mummification in Europe may be older than previously known

Scienmag

Mummification of the dead probably was more common in prehistory than previously known. This discovery is made at the hunter-gatherer burial sites in the Sado Valley in Portugal, dating to 8 000 years ago. A new study, headed by archaeologists at Uppsala University and Linnaeus University in Sweden and University of Lisbon in Portugal, presents new […].

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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New patent expiration for Astrazeneca Ab drug BYDUREON PEN

Drug Patent Watch

Annual Drug Patent Expirations for BYDUREON+PEN Bydureon Pen is a drug marketed by Astrazeneca Ab and is included in one NDA. It is available from one supplier. There are twenty-two…. The post New patent expiration for Astrazeneca Ab drug BYDUREON PEN appeared first on DrugPatentWatch - Make Better Decisions.

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A new molecular family tree of grasses

Scienmag

The evolutionary relationships among grasses—including important crop plants like wheat, rice, corn, and sugarcane—have been clarified in new molecular study of the grass family tree. Having a clear picture of the relationships among the grasses can help understanding of how important crop traits like seed size or disease resistance evolves and eventually could inform manipulation […].

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New patent expiration for Astrazeneca Ab drug BYDUREON

Drug Patent Watch

Annual Drug Patent Expirations for BYDUREON Bydureon is a drug marketed by Astrazeneca Ab and is included in two NDAs. It is available from one supplier. There are twenty-three patents…. The post New patent expiration for Astrazeneca Ab drug BYDUREON appeared first on DrugPatentWatch - Make Better Decisions.

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Finding drugs for formerly undruggable cancer targets

Scienmag

With a $2 million recruitment grant from the Cancer Prevention and Research Institute of Texas (CPRIT), a University of Houston researcher is setting up a lab to develop drugs that will work on traditionally undruggable targets in cancer. Gül Zerze, assistant professor in the William A. Brookshire Department of Chemical and Biomolecular Engineering at the […].

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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New patent expiration for Astrazeneca Ab drug BYDUREON BCISE

Drug Patent Watch

Annual Drug Patent Expirations for BYDUREON+BCISE Bydureon Bcise is a drug marketed by Astrazeneca Ab and is included in one NDA. It is available from one supplier. There are fifteen…. The post New patent expiration for Astrazeneca Ab drug BYDUREON BCISE appeared first on DrugPatentWatch - Make Better Decisions.

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University of Minnesota study details how some fish cope with parasites, with implications for human health

Scienmag

They thrive everywhere from bustling cities to remote rainforests — even in our own backyards. Pervasive and unapologetic mooches, parasites rely on other organisms for their survival. Credit: Amanda Hund, University of Minnesota. They thrive everywhere from bustling cities to remote rainforests — even in our own backyards. Pervasive and unapologetic mooches, parasites rely on […].

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New patent expiration for Bayer Hlthcare drug SAFYRAL

Drug Patent Watch

Annual Drug Patent Expirations for SAFYRAL Safyral is a drug marketed by Bayer Hlthcare and is included in one NDA. It is available from two suppliers. There are three patents…. The post New patent expiration for Bayer Hlthcare drug SAFYRAL appeared first on DrugPatentWatch - Make Better Decisions.

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Woods Hole Oceanographic Institution-led study explores effects of noise on marine life

Scienmag

Woods Hole, MA (March 2, 2022) – New research shows turtles can experience temporary hearing loss from an excess of underwater noise. This phenomenon, previously noted in other marine animals such as dolphins and fish, was not widely understood for reptiles and underscores another potential risk for aquatic turtles. This high volume of sound, referred […].

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.