Sat.Aug 29, 2020

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Novartis new analysis shows high consistency in lowering LDL-C in individual response with investigational inclisiran

The Pharma Data

Pooled data from Phase III ORION-10 and -11 showed highly consistent efficacy, tolerability and safety profile over 17 months on twice-yearly subcutaneous dosing in 2,300 patients (of which 1,164 were on inclisiran) 1 . New post-hoc analysis demonstrates 99% of patients treated with inclisiran showed placebo-adjusted reduction in low-density lipoprotein cholesterol (LDL-C) of ?

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Bio-Rad iCycler PCR Thermal Cycler 96-Well Reaction Module Tested With Warranty

BioTech 365

$595.00End Date: Sunday Sep-13-2020 12:15:30 PDTBuy It Now for only: $595.

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Covid warning as a million students set for uni return

The Pharma Data

Image caption. University buildings have highly visible messages reminding students about safety messages. Universities in the UK are being urged to scrap plans for face-to-face teaching until Christmas in order to prevent a second wave of coronavirus. Academics’ union, UCU, said more than a million students moving around the country was “a recipe for disaster” UCU leader Jo Grady said universities were not prepared, and risked becoming the “care homes of the second wave&

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What happens when babies with heart defects become adults?

Scienmag

ESC Guidelines for the management of adult congenital heart disease Sophia Antipolis, France – 29 Aug 2020: More than 90% of babies born with heart defects survive into adulthood. As a result, there are now more adults living with congenital heart disease than children. These adults have a chronic, lifelong condition and the European Society […].

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Novartis announces positive results from Phase II study of LNP023 in patients with paroxysmal nocturnal hemoglobinuria (PNH)

The Pharma Data

Oral, investigational complement factor B inhibitor LNP023 substantially improved hematological response as add-on therapy to eculizumab. Seven of ten patients discontinued eculizumab and remained on LNP023 as monotherapy, retaining hemoglobin (Hb) levels with no changes in biomarkers of disease activity and with no signs or symptoms of breakthrough hemolysis .

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Risk of heart attacks halves in patients with diabetes in 15 years

Scienmag

Sophia Antipolis, France – 29 Aug 2020: Dramatic reductions in the risk of heart attacks in patients with diabetes coincides with major increases in the use of preventive medications. That’s the finding of late breaking research presented today at ESC Congress 2020.1 “Our results suggest that when patients are diagnosed with type 2 diabetes, starting […].

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Godwin receives funding for performance project exploring human migration

Scienmag

Adrienne Bryant Godwin, Director of Programming, received $9,000 from the National Endowment for the Humanities for: “Cartography – Great Performances at Mason 2020-2021 season.” “CARTOGRAPHY” is a work that explores the global issue of migration through the eyes of four children. The work is designed for audiences ages 10 and older, and allows viewers to […].

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Shimadzu SIL 10A Auto Sampler w/ Injector for HPLC System

BioTech 365

CHF 630,15Angebotsende: Freitag Sep-25-2020 5:08:06 CESTSofort-Kaufen für nur: CHF 630,15Sofort-Kaufen | Zur Liste der beobachteten Artikel hinzufügen Biotech365 : Shimadzu SIL 10A Auto Sampler w/ Injector for HPLC System BioMarketplace You want to propose your products or a Biotech Company, … Continue reading →

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Can’t be away from your phone? Study finds link to higher levels of obsession-compulsion

Scienmag

Researchers looked at “nomophobia” among young people in Portugal COLUMBUS, Ohio – Feelings of panic when a person is away from their smartphone could be connected to general feelings of inadequacy and inferiority, a new study of young people in Portugal suggests. The study, published in the most recent issue of the journal Computers in […].

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Zeiss Microscope Optovar Magnification Changer Großfeld Large Field – Selten!

BioTech 365

EUR 380,00Angebotsende: Montag Sep-28-2020 23:34:27 CESTSofort-Kaufen für nur: EUR 380,00Sofort-Kaufen | Zur Liste der beobachteten Artikel hinzufügen Biotech365 : Zeiss Microscope Optovar Magnification Changer Großfeld Large Field – Selten!

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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How to treat the most common heart attacks

Scienmag

ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation Sophia Antipolis, France – 29 Aug 2020: One in five patients die within a year after the most common type of heart attack. European Society of Cardiology (ESC) treatment guidelines for non-ST-segment elevation acute coronary syndrome are published online […].

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Vintage c1860 ~ “Nachet Et Fils” Brass Microscope with Case #455

BioTech 365

91,88 EUR (21 Pujas)Fecha de finalización: domingo ago-30-2020 22:05:44 CESTPujar ahora | Añadir a lista de seguimiento Biotech365 : Vintage c1860 ~ “Nachet Et Fils” Brass Microscope with Case #455 BioMarketplace You want to propose your products or a Biotech … Continue reading →

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Coronavirus: Secondary schools to move to rota system if virus cases rise

The Pharma Data

Image copyright. PA Media. Secondary schools in areas with significant rises in Covid-19 cases could be put on a rota system limiting the number of pupils attending. New guidance for England says the measure is intended to reduce the number of people students are in contact with and limit transmission. The education secretary said the move would be an “absolute last resort” The guidance, published on Friday night, comes just days before millions of pupils go back to school.

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Nikon microscope Frame. Body. Mount Size Is 60mm

BioTech 365

33,61 EUR (0 Pujas)Fecha de finalización: domingo ago-30-2020 9:05:52 CESTPujar ahora | Añadir a lista de seguimiento Biotech365 : Nikon microscope Frame. Body.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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ANTIQUE DISSECTING MICROSCOPE

BioTech 365

50,42 EUR (0 Pujas)Fecha de finalización: martes sep-8-2020 19:00:23 CESTPujar ahora | Añadir a lista de seguimiento Biotech365 : ANTIQUE DISSECTING MICROSCOPE BioMarketplace You want to propose your products or a Biotech Company, a Biotech Tool or a Bioinformatic software … Continue reading →

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Microscopio digitale USB 3.0 ingrandimento 1600X 2MP con 8-LED E Stand

BioTech 365

EUR 17,89Scadenza: giovedì set-17-2020 8:55:54 CESTCompralo Subito per soli: EUR 17,89Compralo Subito | Aggiungi all’elenco degli oggetti che osservi Biotech365 : Microscopio digitale USB 3.

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AFFYMETRIX GENEATLAS IMAGING STATION ! (249194)

BioTech 365

CHF 813,68Angebotsende: Dienstag Sep-29-2020 19:36:21 CESTSofort-Kaufen für nur: CHF 813,68Sofort-Kaufen | Zur Liste der beobachteten Artikel hinzufügen Biotech365 : AFFYMETRIX GENEATLAS IMAGING STATION !

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Macherey & Nagel NANOCOLOR 400D Photometer Wasseranalythik

BioTech 365

EUR 290,00Angebotsende: Dienstag Sep-1-2020 9:48:01 CESTSofort-Kaufen für nur: EUR 290,00Sofort-Kaufen | Zur Liste der beobachteten Artikel hinzufügen Biotech365 : Macherey & Nagel NANOCOLOR 400D Photometer Wasseranalythik BioMarketplace You want to propose your products or a Biotech Company, a Biotech Tool … Continue reading →

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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Empagliflozin reduced the combined relative risk of cardiovascular death and hospitalization for heart failure by 25 percent in adults with and without diabetes who had heart failure with reduced ejection fraction

BioTech 365

Empagliflozin also significantly reduced the relative risk of first and recurrent hospitalization for heart failure by 30 percent and significantly slowed kidney function decline1 Results were consistent in subgroups with and without type 2 diabetes1 Heart failure is the leading … Continue reading →

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VASCEPA® (Icosapent Ethyl) Reported to Significantly Reduce Coronary Plaque in EVAPORATE Study Final Results Presented at ESC Congress 2020

BioTech 365

Primary endpoint of slowed coronary plaque progression reported to have been met with VASCEPA Significant coronary plaque regression of low attenuation plaque (LAP) reported with VASCEPA provides further insight to potential mechanisms of action VASCEPA is the first and only … Continue reading →

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LAMPADA STROBO PERKINELMER BUB0641RD(G)(H)

BioTech 365

EUR 6,10Scadenza: domenica set-27-2020 11:57:12 CESTCompralo Subito per soli: EUR 6,10Compralo Subito | Aggiungi all’elenco degli oggetti che osservi Biotech365 : LAMPADA STROBO PERKINELMER BUB0641RD(G)(H) BioMarketplace You want to propose your products or a Biotech Company, a Biotech Tool or … Continue reading →

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bluebird bio Presents New Results from Clinical Development Program of elivaldogene autotemcel (eli-cel, Lenti-D™) Gene Therapy for Cerebral Adrenoleukodystrophy (CALD), Including Updated Long-Term Data, at the 46th Annual Meeting of the EBMT

BioTech 365

Long-term results from Phase 2/3 Starbeam study (ALD-102/LTF-304) suggest durability of response post eli-cel with all 20 patients who were free of major functional disabilities (MFDs) at two years (out of 23 evaluable patients) remaining MFD-free through last available follow-up, … Continue reading →

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Mirum Pharmaceuticals Presents Maralixibat Five-Year Transplant-Free Survival Data for Patients With PFIC2 at Digital International Liver Congress 2020

BioTech 365

Maralixibat demonstrates significant transplant-free survival for patients with progressive familial intrahepatic cholestasis (PFIC2) who achieved serum bile acid (sBA) control in five-year analysis (p=0.0006).

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Novartis announces positive results from Phase II study of LNP023 in patients with paroxysmal nocturnal hemoglobinuria (PNH)

BioTech 365

Oral, investigational complement factor B inhibitor LNP023 substantially improved hematological response as add-on therapy to eculizumab Seven of ten patients discontinued eculizumab and remained on LNP023 as monotherapy, retaining hemoglobin (Hb) levels with no changes in biomarkers of disease activity … Continue reading →

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NGM Bio Presents Comprehensive Findings from 24-Week Phase 2 Study (Cohort 4) of Aldafermin in Oral Plenary Presentation at The Digital International Liver Congress™ (ILC) 2020 and Announces Enrollment Completed in Phase 2b ALPINE 2/3 Study

BioTech 365

Late-breaker presentation selected as “Best of ILC” The 24-week Phase 2 study met its primary endpoint, achieving a statistically significant reduction in liver fat content (LFC), and robust fibrosis improvement and resolution of NASH, with a favorable safety profile New … Continue reading →

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MyoKardia Presents Results from Phase 3 EXPLORER-HCM Clinical Trial of Mavacamten for the Treatment of Obstructive Hypertrophic Cardiomyopathy

BioTech 365

EXPLORER-HCM Data Presented During Live Hot Line Session at ESC Congress 2020 with Simultaneous Publication in The Lancet Presentation Expands on Positive Topline Results Showing Early, Sustained Reductions in Biomarkers of Cardiac Wall Stress and Myocardial Injury Mavacamten Demonstrated Broad … Continue reading →

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.

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#news #biotech ESC: MyoKardia’s mavacamten boosts heart function in phase 3, teeing up 2021 filing

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: ESC: MyoKardia’s mavacamten boosts heart function in phase 3, teeing up 2021 filing.

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Kiadis announces new data demonstrating FC21-NK cells were well tolerated and showed encouraging signs of antitumor and suspected antimicrobial activity in 13 patients with relapsed/refractory acute myeloid leukemia (R/R AML)

BioTech 365

New data will be presented in an e-poster today at the Virtual Edition of the 46th EBMT Annual Meeting Amsterdam, The Netherlands, August 29, 2020 – Kiadis Pharma N.V.

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Medtronic Cryoablation Superior to Drug Therapy for Symptomatic Paroxysmal Atrial Fibrillation

BioTech 365

ESC Congress: New Research Highlights First-Line Use of Cryoablation as Highly Effective, and with Improved Quality of Life Scores DUBLIN, Aug.

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QIAGEN Qiagility Schnell Hohe Präzision Automatisierte Pcr Aufbau W/Software

BioTech 365

EUR 3.502,40Angebotsende: Dienstag Sep-29-2020 5:44:15 CESTSofort-Kaufen für nur: EUR 3.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.