Sat.Jan 30, 2021

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How the Search for Covid-19 Treatments Faltered While Vaccines Sped Ahead

NY Times

Vaccine development exceeded everyone’s expectations. But the next few months will still bring many sick people — and doctors have woefully few drugs with which to treat them.

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TALENT study supports NLCST and NELSON trial results

Scienmag

Research presented at International Association for the Study of Lung Cancer World Conference on Lung Cancer (Singapore–January 30, 2021 11:00 p.m. SPT/January 30, 2021 10:00 a.m. EST)– A study presented today by researchers with the Ministry of Health and Welfare in Taiwan confirmed the effectiveness of low-dose computed tomography (LDCT) screening in a pre-defined, never-smoker, […].

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New patent expiration for Allergan drug LATISSE

Drug Patent Watch

Annual Drug Patent Expirations for LATISSE Latisse is a drug marketed by Allergan and is included in one NDA. It is available from one supplier. There are eleven patents protecting…. The post New patent expiration for Allergan drug LATISSE appeared first on DrugPatentWatch - Make Better Decisions.

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Women undergo less aggressive open heart surgery, experience worse outcomes than men

Scienmag

Delayed diagnosis of heart disease may contribute to surgical disparity CHICAGO (January 30, 2021) — Women are significantly less likely than men to undergo coronary artery bypass grafting (CABG) using guideline-recommended approaches, which may result in worse outcomes after surgery, according to a scientific presentation at the 57th Annual Meeting of The Society of Thoracic […].

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Kiss Chapped Lips Goodbye This Winter

The Pharma Data

News. Consumer News. Kiss Chapped Lips Goodbye This Winter. SATURDAY, Jan. 30, 2021 — Dry and chapped lips are common during the winter, but there are a number of things you can do to protect them, an expert says. “Cold, dry weather; sun damage; and frequently licking your lips are just some of the reasons your lips might feel dry and chapped this winter,” dermatologist Dr.

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Social & structural factors influence racial disparities in COVID-19 mortality

Scienmag

Rutgers study finds counties with higher percentage of adults without a high school diploma and households without internet access were strong predictors of COVID-19 mortality COVID-19 mortality racial disparities in the U.S. are associated with social factors like income, education and internet access, according to a Rutgers study. The study, published in the Journal of […].

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Selected gene mRNA expression is not predictive of improved overall survival

Scienmag

Research presented at International Association for the Study of Lung Cancer World Conference on Lung Cancer (Singapore–January 30, 2021 11:00 p.m. SPT/January 30, 2021 10:00 a.m. EST)– A phase III study examining whether messenger (m)RNA expression correlated with sensitivity or resistance to chemotherapy did not confer a statistically significant advantage in overall survival for patients […].

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Which pharmaceutical companies have the most drug patents in Finland?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Finland. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is…. The post Which pharmaceutical companies have the most drug patents in Finland? appeared first on DrugPatentWatch - Make Better Decisions.

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‘COVID effect’ leads to fewer heart surgeries, more patient deaths

Scienmag

Landmark study examines the pandemic’s impact on adult cardiac surgery in the US CHICAGO (January 30, 2021) — The most deadly global health crisis in a century has resulted in a substantial decline in overall heart surgery volume and an unexplained increase in deaths after coronary artery bypass grafting, according to late-breaking research presented at […].

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Edwards RESILIA Tissue Aortic Valve Demonstrates Favorable Safety and Efficacy at Five Years

The Pharma Data

AUSTIN, Texas , Jan. 31, 2021 /PRNewswire/ — Edwards Lifesciences (NYSE: EW) today announced new data from the COMMENCE clinical trial that demonstrate Edwards’ bioprosthetic surgical aortic valve with the company’s novel RESILIA tissue platform show favorable safety and hemodynamic performance through a median of five years follow-up.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Host immune classifier HIC assays may predict treatment response

Scienmag

Research presented at IASLC 2020 World Conference on Lung Cancer Singapore (Singapore–4:45 p.m. SPT/3:45 a.m. EST January 30, 2021–Using a host immune classifier (HIC) test for patients with non-small cell lung cancer (NSCLC) may provide better predictors of treatment response and improve outcomes, according to research presented today at the International Association for the Study […].

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LCMC3: Neoadjuvant atezolizumab safe, meets primary endpoint of pathologic response rate

Scienmag

Research presented at the International Association for the Study of Lung Cancer’s World Conference on Lung Cancer (Singapore–January 30, 2021 11:00 p.m. SPT/January 30, 2021 10:00 a.m. EST)– Primary analysis of the Lung Cancer Mutation Consortium (LCMC) 3 study revealed that neoadjuvant atezolizumab prior to lung cancer surgery was well tolerated by patients and met […].

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Patient-reported outcomes from the randomized phase III CROWN study of first-line Lorlatinib versus in ALK+ NSCLC

Scienmag

(Singapore–January 31, 2021 2:40 p.m. SPT 1:40 a.m. EST)–Patient-reported outcomes from the phase III CROWN study showed that time to treatment deterioration (TTD) in pain in chest, dyspnea, and cough was comparable between those who received lorlatinib and patients who took crizotinib. The research was presented today at the International Association for the Study of […].

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ERAS program expedites recovery for congenital heart surgery patients

Scienmag

Study shows multidisciplinary pediatric care improves patient outcomes and experiences CHICAGO (January 30, 2021) — Select patients born with heart defects and who undergo congenital heart surgery recover with few complications and reduced opioid use when a comprehensive, evidence-based enhanced recovery after surgery (ERAS) program is used, according to research presented at the 57th Annual […].

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Nivolumab effective treatment for malignant mesothelioma

Scienmag

Research presented at International Association for the Study of Lung Cancer World Conference on Lung Cancer (Singapore–January 30, 2021 11:00 p.m. SPT/January 30, 2021 10:00 a.m. EST)– Nivolumab monotherapy is an effective treatment option for relapsed malignant mesothelioma (MM), according to research presented today at the International Association for the Study of Lung Cancer World […].