Sun.Feb 27, 2022

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Mindfulness-Oriented Recovery Enhancement for Co-Occurring Opioid Misuse and Chronic Pain

JAMA Internal Medicine

This randomized clinical trial assesses whether Mindfulness-Oriented Recovery Enhancement is more efficacious than supportive group psychotherapy for reducing opioid misuse among adults with chronic pain receiving long-term opioid therapy.

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New low-cost dialysis system can make medical grade water in the home, giving green light to progress to clinical trials

Scienmag

Findings from preliminary tests of a new dialysis system have confirmed its ability to make sterile, medical grade water to provide an affordable, accessible home-based treatment option for patients with kidney failure. This means that the Ellen Medical Devices Point-of-Care dialysis system can create peritoneal dialysis fluid (a mix of sterile water, electrolytes, and glucose) […].

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Association Between Generic Levothyroxine Switching and Thyrotropin Levels

JAMA Internal Medicine

This comparative effectiveness research study examines whether an association exists between switching generic levothyroxine products and changes to serum thyrotropin levels.

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Seismic study reveals key reason why Patagonia is rising as glaciers melt

Scienmag

The icefields that stretch for hundreds of miles atop the Andes mountain range in Chile and Argentina are melting at some of the fastest rates on the planet. The ground that was beneath this ice is also shifting and rising as these glaciers disappear. Geologists have discovered a link between recent ice mass loss, rapid […].

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Physician Management Companies and Commercial Health Care Prices Paid to Anesthesia Practitioners

JAMA Internal Medicine

This cohort study assesses changes in prices paid to practitioners (anesthesiologists and certified registered nurse anesthetists) before and after an outpatient facility contracted with a physician management company.

Nurses 74
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Physical fitness linked to lower risk of Alzheimer’s disease

Scienmag

MINNEAPOLIS – People who are more physically fit are less likely to develop Alzheimer’s disease than people who are less physically fit, according to a preliminary study released today, February 27, 2022, that will be presented at the American Academy of Neurology’s 74th Annual Meeting being held in person in Seattle, April 2 to 7, […].

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Antibiotic doesn’t prevent future wheezing in babies hospitalized with RSV

Scienmag

The antibiotic azithromycin has anti-inflammatory properties that can be beneficial in some chronic lung diseases, such as cystic fibrosis. With that in mind, researchers investigated its potential to prevent future recurrent wheezing among infants hospitalized with respiratory syncytial virus (RSV). With such babies at increased risk of developing asthma later in childhood, the scientists hoped […].

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Which pharmaceutical companies have the most drug patents in Brazil?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Brazil. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is…. The post Which pharmaceutical companies have the most drug patents in Brazil? appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 98
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Inappropriate use of 228 clinical practices in Canada

Scienmag

A new study has identified 228 clinical practices in Canada that are used inappropriately, with underuse being more common than overuse. This list includes diagnostic and therapeutic practices such as blood tests and radiography. Published in CMAJ (Canadian Medical Association Journal), the research can help health care professionals, organizations and governments improve patient care and health […].

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Orphazyme ‘looking at options’ after lead drug hits buffers in EU

pharmaphorum

Orphazyme’s hopes of getting EU approval for its Niemann-Pick disease type C (NPC) therapy arimoclomol after a rejection by the US FDA last year are dwindling fast. The EMA’s human medicines committee has told Orphazyme it is unlikely to recommend approval of arimoclomol for the ultra rare genetic condition at its next meeting in March, prompting the Danish biotech to assess its “strategic options.” Copenhagen-based Orphazyme was summoned to deliver an oral presentation i

Drugs 52
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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Study finds azithromycin use during RSV not useful in preventing recurrent wheezing, may cause harm

Scienmag

Findings from a recent study evaluating the impact of the antibiotic azithromycin during severe respiratory syncytial virus (RSV) bronchiolitis overwhelmingly support current national bronchiolitis guidelines, which recommend against antibiotics during acute bronchiolitis due to lack of effect on the acute illness. There is also substantial evidence that severe RSV bronchiolitis in early life increases the […].

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Computer drug simulations offer warning about promising diabetes and cancer treatment

Scienmag

Using computer drug simulations, researchers have found that doctors need to be wary of prescribing a particular treatment for all types of cancer and patients. The drug, called metformin, has traditionally been prescribed for diabetes but has been used in clinical settings as a cancer treatment in recent years. The researchers say while metformin shows great promise, it also has […].

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