Thu.Feb 24, 2022

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Amicus' SPAC deal unravels, leading to layoffs and cost cuts

Bio Pharma Dive

The biotech is calling off plans to spin out its gene therapy business via a merger with a blank check company, citing unfavorable market conditions and a "challenging environment.

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Frequency on pharma TV too high

World of DTC Marketing

Ninety-two percent of U.S. viewers surveyed in 2021 believe “they see the same advertisements too many times when watching TV,” according to a new study by Audience Project. Nowhere is this more evident than in pharma TV ads like Tepezza. Thyroid eye disease affects more women than men, although men are more likely to have severe illnesses.

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Moderna bets on booster demand, advancing new 'bivalent' COVID-19 shot

Bio Pharma Dive

The biotech will start trials in the U.S. and U.K. of a vaccine that targets both the original coronavirus strain and the omicron variant.

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Ways to Access Affordable Mental Health Services

Pharma Mirror

Taking care of your mental health can be affordable. All you will have to do is choose therapy options that fit in your budget. In this article, we have outlined the most affordable therapy options. While the options fall in the lower price range, they are all capable of delivering your expected results. The post Ways to Access Affordable Mental Health Services appeared first on Pharma Mirror Magazine.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Allogene, slipping in 'off-the-shelf' CAR-T race, prepares for key trials

Bio Pharma Dive

Allogene, once the clear leader in development of a more convenient option to personalized cancer cell therapies, now is competing with CRISPR Therapeutics and other fast-emerging rivals.

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Data from first DMT-assisted clinical trial revealed

Pharma Times

No sign of significant negative effects on anxiety and wellbeing following pioneering Small Pharma trial

More Trending

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Moderna and Thermo Fisher Scientific announce 15-year mRNA manufacturing deal

BioPharma Reporter

Moderna and Thermo Fisher Scientific have announced a 15-year strategic collaboration agreement to enable dedicated large-scale manufacturing of COVID-19 vaccine Spikevax in the US, as well as other investigational mRNA vaccines and therapies.

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Imagindairy is on a Mission to Make Cow-Free Milk the New Norm

XTalks

Imagindairy, an animal-free dairy protein maker, is one step closer to commercializing cow-free milk. But we’re not talking about plant-based milk alternatives like soy or oat milk. We’re talking about milk with dairy proteins. Imagindairy seemingly answered the age-old question: why buy the cow when the milk is free? . The Tel Aviv-based food tech company developed a proprietary technology to produce dairy proteins without the cow by leveraging natural precision fermentation.

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How new data capabilities can supercharge clinical research

pharmaphorum

The UK’s health research data capabilities are rapidly evolving. For example, during the height of the pandemic, NIHR’s integrated health research system was able to compare COVID-19 hospital caseloads to COVID-19 research activity in real time. This enabled rapid recruitment to multiple COVID-19 clinical trials throughout England/UK. . In a post-pandemic world, how can we use insights gained from healthcare and research activity data to inform commercial research planning and placement decisio

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Report shines a light on unique challenges of rare disease patients

Outsourcing Pharma

In its latest diversity, equity and inclusion report, Global Genes offers insight into obstacles faced by rare-disease patients from minority communities.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Prize-winning work informs who is most at-risk from COVID-19, so physicians could tailor treatment

Scienmag

The COVID-19 pandemic has revealed a frightening reality; the course of infection with this disease is highly variable. Some young patients have died from the virus, whereas several elderly people have survived without experiencing respiratory symptoms at all. Researchers are left wondering: why? For illuminating factors that underlie these varied susceptibilities – through efforts that […].

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Data delivery: Sanofi and GSK seek authorisation for COVID-19 vaccine

Pharma Times

Pharma giants take major stride as vaccine shows significant increase in neutralising antibodies

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Development of a diamond transistor with high hole mobility

Scienmag

Using a new fabrication technique, NIMS has developed a diamond field-effect transistor (FET) with high hole mobility, which allows reduced conduction loss and higher operational speed. This new FET also exhibits normally-off behavior (i.e., electric current flow through the transistor ceases when no gate voltage is applied, a feature that makes electronic devices safer).

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Cantex secures license to develop small molecule-drug for inflammatory lung diseases

pharmaphorum

Clinical stage pharmaceutical company Cantex Pharmaceuticals has obtained a global licence from Harvard University’s Office of Technology Development to develop the small-molecule drug azeliragon into a treatment for inflammatory lung diseases, including COVID-19. Viral or bacterial infections, or airway irritants can damage lung cells, causing them to release damage associated molecular pattern (DAMP) molecules that attach to and activate the receptor for advanced glycation endproducts (RAGE) p

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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The algebra of neurons

Scienmag

Neurons are constantly performing complex calculations to process sensory information and infer the state of the environment. For example, to localize a sound or to recognize the direction of visual motion, individual neurons are thought to multiply two signals. However, how such a computation is carried out has been a mystery for decades. Researchers at […].

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Genomenon forges rare-disease partnership with advocacy group

Outsourcing Pharma

The AI-centered genomics company is joining with Donât Forget Morgan, a group for patients with BPAN, to explore treatments for the neurodegenerative condition.

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DOE ARPA-E awards $10M to U of I researchers to develop clean enegy technologies

Scienmag

Three out of the 68 research and development projects nationwide aimed at developing disruptive technologies to strengthen the U.S. advanced energy enterprise were awarded to POETS faculty, including MechSE Associate Professor Nenad Miljkovic. Credit: University of Illinois Urbana-Champaign, The Grainger College of Engineering Three out of the 68 research and development projects nationwide aimed at developing […].

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Drug Channels News Roundup, February 2022: Mark Cuban vs. Generics, Novo Nordisk’s G2N, CVS & 340B, and My Favorite Chart

Drug Channels

Winter—or at least February—is almost over. Celebrate the imminent return of spring with our selection of noteworthy news from around the drug channel. In this issue: Mark Cuban! Novo Nordisk confronts the gross-to-net bubble CVS Health finally acknowledges its profits from the 340B program Plus, an update to my all-time favorite chart. P.S. Please join the nearly 13,500 consumers of my daily commentary and links to neat stuff at @DrugChannels on Twitter.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Live wire: new research on nanoelectronics

Scienmag

Proteins are among the most versatile and ubiquitous biomolecules on earth. Nature uses them for everything from building tissues to regulating metabolism to defending the body against disease. Credit: The Biodesign Institute at Arizona State University Proteins are among the most versatile and ubiquitous biomolecules on earth. Nature uses them for everything from building tissues […].

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CRA Must Have Gadgets

ECRG Media's Clinical Research Podcast

CRA Must Have Gadgets Don't forget to Subscribe for new content! Merch: [link] [link] eliteclinicalgroup@gmail.com Podcast: [link] [link] eliteclinicalgroup@gmail.com Watch: » Industry News: [link] All Videos: [link] Interview Recaps: [link] Glassdoor Reviews: [link] We do: » Insider Interviews » Resume Reviews » Question and Answer » Discuss all things Clinical Research » News and Product Reviews » Education Elite Clinical Research Group or ECRG for short is a content creating conglomerate that

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Vaccination has changed the profile of hospitalized COVID-19 patients and those who die from the disease

Scienmag

Vaccination has changed the profile of hospitalized COVID-19 patients and people who die from the disease in Brazil. A study conducted in São José do Rio Preto, in the state of São Paulo, Brazil, reports on the start of this process. Credit: Fábio Rodrigues Pozzebom/Agência Brasil Vaccination has changed the profile of hospitalized COVID-19 patients […].

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CRA Must Have Gadgets

ECRG Media's Clinical Research Podcast

CRA Must Have Gadgets. Don't forget to Subscribe for new content! Merch: [link] [link] eliteclinicalgroup@gmail.com Podcast: [link] [link] eliteclinicalgroup@gmail.com Watch: » Industry News: [link] All Videos: [link] Interview Recaps: [link] Glassdoor Reviews: [link] We do: » Insider Interviews » Resume Reviews » Question and Answer » Discuss all things Clinical Research » News and Product Reviews » Education.

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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New therapy breakthrough changes the shape of treatment for undruggable diseases

Scienmag

For some time, scientists have been working on the major challenge of developing new therapies against many human diseases. Many of these diseases are caused by the abberant action of certain proteins in our cells that are considered “undruggable”, or difficult to therapeutically target using classical drug discovery methods. A major class of “undruggable” proteins […].

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Allergan, an AbbVie Company, to Present Data from its Leading Portfolio of Eye Care Treatments at the 2022 American Glaucoma Society (AGS) Annual Meeting

The Pharma Data

Allergan, an AbbVie (NYSE: ABBV) company, today announced new data to be presented from Allergan’s leading portfolio of eye care treatments at the 2022 American Glaucoma Society (AGS) Annual Meeting being held in Nashville, TN and virtually from March 3-6. Presentations will include updated analyses that help further scientific understanding of DURYSTA ® (bimatoprost intracameral implant), as well as new data on the XEN ® Gel Stent.

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Purdue invention to improve health and welfare of farrowing sows is licensed to Canadian company

Scienmag

WEST LAFAYETTE, Ind., and WINNIPEG, Manitoba — A patented Purdue University invention designed to cool sows and lower their respiration rate while farrowing has been licensed to Innovative Heating Technologies for further beta testing and commercialization. Credit: (Purdue Agricultural Communication photo/Tom Campbell) WEST LAFAYETTE, Ind., and WINNIPEG, Manitoba — A patented Purdue University invention designed to cool […].

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FDA Grants BI 1015550 Breakthrough Therapy Designation for Idiopathic Pulmonary Fibrosis

The Pharma Data

Designation is supported by Phase II efficacy and safety data that will be presented at ATS 2022 Boehringer Ingelheim plans to study this novel investigational therapy in patients with progressive fibrosing interstitial lung diseases. Boehringer Ingelheim announced today that the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation to its novel investigational therapy, BI 1015550, for the treatment of idiopathic pulmonary fibrosis (IPF).

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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New study finds reporting entanglements of leatherback turtles is critical for survival

Scienmag

New research suggests that leatherback turtles entangled in fishing gear have a better chance of survival if the incident is reported quickly, giving trained responders the opportunity to fully disentangle the animals. Credit: Center for Coastal Studies; disentanglement authorized under 50 CFR 222.310 New research suggests that leatherback turtles entangled in fishing gear have a […].

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Bayer extends clinical development program for finerenone with Phase II study investigating the initial combination therapy with empagliflozin in patients with chronic kidney disease and type 2 diabetes

The Pharma Data

There is a high unmet need for new treatments to preserve kidney function and delay kidney disease progression in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) / The Phase II CONFIDENCE study will investigate the effect of the simultaneous initiation of combination therapy with finerenone and the SGLT2 inhibitor empagliflozin in patients with CKD and T2D.

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A new dimension in Stem Cell Signaling

Scienmag

Divide, differentiate or die? Making decisions at the right time and place is what defines a cell’s behavior and is particularly critical for stem cells of an developing organisms. Decision making relies on how information is processed by networks of signaling proteins. The teams around Christian Schröter from the Max Planck Institute of Molecular Physiology […].

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Medicago and GSK announce the approval by Health Canada of COVIFENZ®, an adjuvanted plant-based COVID-19 vaccine

The Pharma Data

A vaccine manufactured in plants and developed in Canada. Medicago, a biopharmaceutical company headquartered in Quebec City, and GlaxoSmithKline (GSK) today announced that Health Canada has granted approval for COVIFENZ®, COVID-19 vaccine, (plant-based virus-like particles [VLP], recombinant, adjuvanted). This vaccine is indicated for active immunization to prevent coronavirus disease 2019 (COVID?

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.