pharmaphorum

MARCH 13, 2022

The FDA has cleared AstraZeneca and Merck & Co’s Lynparza as an adjuvant or neoadjuvant treatment for breast cancer, extending its lead over pretenders to its PARP inhibitor crown. The new approval is for use in patients with BRCA-mutated, HER2-negative early-stage breast cancer who have already been treated with chemotherapy – either before or after surgery – and are at high risk of the disease coming back.

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Sales Trials Drugs Marketing 140

Scienmag

MARCH 13, 2022

A new study estimates that over the next 30 years, 1.4 million street trees will be killed by invasive insects, costing over 900 million dollars to replace. The findings are published in the British Ecological Society’s Journal of Applied Ecology. Researchers from McGill University, the USDA Forest Service Southern Research Station and North Carolina State […].

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Scientist Research 92

JAMA Internal Medicine

MARCH 13, 2022

This systematic review and meta-analysis examines the association between absolute reductions in low-density lipoprotein cholesterol levels with treatment with statin therapy and all-cause mortality, myocardial infarction, and stroke.

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Scienmag

MARCH 13, 2022

Researchers aim to streamline the time- and resource-intensive process of screening ligands during catalyst design by using virtual ligands. Credit: Wataru Matsuoka, Yu Harabuchi, Satoshi Maeda. ACS Catalysis. March 13, 2022 Researchers aim to streamline the time- and resource-intensive process of screening ligands during catalyst design by using virtual ligands.

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Clinical Research

The Pharma Data

MARCH 13, 2022

People who gained immunity – either through vaccination or exposure – against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen’s omicron variant. That’s because the mutations that led to the variant’s emergence aren’t found in the regions of the virus that stimulates one type of cellular immune response, says an international research team from Johns Hopkins Medicine, in collaboration with the Nation

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Scienmag

MARCH 13, 2022

The Korea Institute of Machinery and Materials (President Sang Jin Park, hereafter referred to as KIMM), an institute under the jurisdiction of the Ministry of Science and ICT, has successfully developed a new stretchable meta-display technology that can be stretched up to 25% without image distortion, for the first time in the world. Credit: The […].

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Development Engineer 79

Scienmag

MARCH 13, 2022

The road salt that makes your drive to work easier on snowy days may be damaging the water quality in local rivers and streams long after winter is over. A new study led by University of Maryland scientists sheds light on how salinization from winter road salt combined with other pollutants creates “chemical cocktails” that […].

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Scientist 64

The Pharma Data

MARCH 13, 2022

“Today, we call for an immediate cessation of all attacks on health care in Ukraine. These horrific attacks are killing and causing serious injuries to patients and health workers, destroying vital health infrastructure and forcing thousands to forgo accessing health services despite catastrophic needs. “To attack the most vulnerable – babies, children, pregnant women, and those already suffering from illness and disease, and health workers risking their own lives to save lives – is an act

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Medicine 52

Scienmag

MARCH 13, 2022

There are practical limits to the height at which aerosols may be deployed in the atmosphere to deflect incoming sunlight and countervail global warming. Very high-altitude injections might be more effective, but such climate intervention comes with substantially increased costs and safety risks, according to new research published today in Environmental Research Communications.

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Roots Analysis

MARCH 13, 2022

Over the years, the rising popularity of biologics has led to a paradigm shift in the healthcare industry. In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines and gene therapies), by the US FDA, have steadily risen. In fact, over 8,000 biological pharmaceutical products are currently under clinical investigation worldwide.

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White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

Clinical Trials

Scienmag

MARCH 13, 2022

Racialized leaders are considerably under-represented in high-level health care leadership in Canada, although there is gender parity, according to a national study of 3056 leaders published in CMAJ (Canadian Medical Association Journal) [link] VIEW EMBARGOED ARTICLE The study included 135 of Canada’s largest hospitals and all provincial and territorial health ministries.

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Drug Patent Watch

MARCH 13, 2022

VIMPAT (lacosamide) Ucb inc Patent: RE38551 Expiration: Mar 17, 2022 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or…. The post Drug Patent Expirations for the Week of March 13, 2022 appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs 40

Scienmag

MARCH 13, 2022

People living with neurological or psychiatric conditions may have an increased likelihood of having a second such condition in the future, and their sex influences their risk, according to new research. The study is Ontario’s largest, both in population size and length of time studied, and was also the first to examine the effect that […].

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Development Research 59

Drug Patent Watch

MARCH 13, 2022

This chart shows the pharmaceutical companies with the most aerosol dosed drugs. For a different perspective, see the most popular dosage types. The companies with the most aerosol dosed drugs…. The post Which pharmaceutical companies have the most aerosol dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.

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When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

Clinical Supply