Pharma Mirror

NOVEMBER 25, 2021

Terrassa (Barcelona) Telstar launches a new global service platform for retrofitting and maintenance of existing freeze-dryers, regardless of brand and model. Under Usifroid brand, this platform is specialized in providing a retrofitting and modernization service together with maintenance services and technical support to freeze-drying equipment for pharmaceutical production and research.

Branding 130

Branding Production Research 130

Pharma Times

NOVEMBER 25, 2021

A team of scientists and pharmaceutical collaborators have discovered a ‘bench to bedside’ drug design, which will hopefully improve the future treatment of Alzheimer’s disease.

Drugs 154

Drugs Scientist 154

pharmaphorum

NOVEMBER 25, 2021

A new variant of COVID-19 identified in Botswana with dozens of mutations is being watched closely, amid fears it could be resistant to the effect of currently-used vaccines. The B.1.1.529 variant has more mutations affecting the spike protein targeted by vaccines than any other strain identified to date, although it’s not yet clear if it is more or less transmissible.

Vaccination 116

Vaccination Vaccine Protein Genetics 116

BioPharma Reporter

NOVEMBER 25, 2021

A new clinical trial of heterologous â or âmix-and-matchâ â combinations of COVID-19 vaccines is set to start in Pakistan: seeking to add to research on the effectiveness of such combinations.

Vaccination 111

Vaccination Vaccine Trials Research 111

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Clinical Research

pharmaphorum

NOVEMBER 25, 2021

Health insurance is not enough to provide the necessary affordable access to care for the US’ most vulnerable, finds new PhRMA report. For too many Americans, insurance coverage is not providing the health security it’s meant to. The Pharmaceutical Research and Manufacturers of America’s (PhRMA) first Patient Experience Survey (PES) has found that three in ten people with medical insurance still face financial barriers to accessing healthcare and prescription medicines.

Medicine 116

Medicine Allergies Manufacturing Research 116

BioPharma Reporter

NOVEMBER 25, 2021

GreenLight Biosciences and CDMO Samsung Biologics have announced a partnership agreement, with Samsung Biologics to manufacture GreenLightâs messenger RNA COVID-19 vaccine candidate at commercial scale.

Manufacturing 105

Manufacturing Vaccination Vaccine RNA 105

pharmaphorum

NOVEMBER 25, 2021

Healthcare professional (HCP) engagement experienced significant shifts during the acute phase of the pandemic, as COVID-19 forced a rethink of traditional pharmaceutical sales and marketing practices, including the digitisation of events. With medical conferences and events long a mainstay for pharma-HCP interactions, the pandemic’s travel restrictions, and lockdowns forced these in-person meet-ups to go virtual.

Pharma Companies 98

Pharma Companies Production Sales Marketing 98

XTalks

NOVEMBER 25, 2021

Even though vegan foods are perceived to be better-for-you products, plant-based alternatives are not always the healthiest when it comes to their ingredients. When trying to mimic chicken, some additives are found in the ingredients list to create the same consistency and texture as natural chicken. Nowadays, the California-based company, has found a way to tackle this non-healthy plant-based product issue by introducing health-focused and plant-based chicken nuggets.

Protein 98

Protein Production Containment 98

pharmaphorum

NOVEMBER 25, 2021

The first patients are now being treated as part of a first-in-human trial of a vaccine, administered as a nasal spray, that aims to slow down the progression of Alzheimer’s disease (AD). Researchers at Brigham and Women’s Hospital in Boston, US, hope that the vaccine will stimulate the immune system to clear the amyloid plaques that are seen in the brains of people with AD and have been linked to the development of dementia.

Vaccination 98

Vaccination Vaccine Trials Immune Response 98

BioPharma Reporter

NOVEMBER 25, 2021

Ncardia, a human-induced pluripotent stem cell-based (iPSC) company, has secured more than US$60m in capital through a strategic partnership with Kiniciti, a US based investment platform with a focus on the global cell and gene therapy ecosystem.

Gene Therapy 95

Gene Therapy Gene Regulation Marketing 95

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White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

Clinical Trials

pharmaphorum

NOVEMBER 25, 2021

Share in Kura Oncology have come under pressure after a patient death in a clinical trial of the US biotech’s acute myeloid leukaemia (AML) therapy KO-539, provisionally attributed to a side effect that plagues other drugs used to treat the cancer. The FDA has placed the trial on partial hold, meaning that patients already in the study can continue to receive the drug, but no new subjects can be treated.

Trials 97

Trials Drugs Clinical Trials Clinical Trials 97

BioPharma Reporter

NOVEMBER 25, 2021

Korean company, SK, is investing in the Philadelphia-based Center for Breakthrough Medicines (CBM), a move that will support the US company in its bid to become the world's largest end-to-end cell and gene therapy contract development and manufacturing organization (CDMO).

Gene Therapy 94

Gene Therapy Gene Manufacturing Medicine 94

Scienmag

NOVEMBER 25, 2021

Pandemic depression persists among older adults: Study Credit: McMaster University Pandemic depression persists among older adults: Study Hamilton, ON (Nov. 25, 2021) – The COVID-19 pandemic has had a significant impact on the mental health of older people living in the community, with those who are lonely faring far worse, according to new research […].

Research 93

Research 93

pharmaphorum

NOVEMBER 25, 2021

Ieso has raised $53 million in second-round financing that will be used to bring its digital therapeutics (DTx) through to market in its home market of the UK, as well as the US. The company’s artificial intelligence-powered software uses cognitive behavioural therapy techniques to help patients suffering from a range of mental health issues, including depression and anxiety.

Production 72

Production Marketing Development 72

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When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

Clinical Supply

Scienmag

NOVEMBER 25, 2021

· Seabird populations under threat due to human activity · University College Cork research could have implications for offshore developments · Birds with tracking devices found to follow fishing vessels for food Credit: University College Cork · Seabird populations under threat due to human activity · University College Cork research could have implications for offshore […].

Research 92

Research Development 92

pharmaphorum

NOVEMBER 25, 2021

The European Medicines Agency (EMA) has approved Pfizer and BioNTech’s COVID-19 vaccine Comirnaty for children between the ages of five and 11, as EU countries struggle to cope with rising infection rates. The EU regulator said that the under-12s should get a lower dose of the vaccine – 10 mcg rather than 30 mcg – given as two intramuscular injections three weeks part.

Vaccination 59

Vaccination Vaccine Medicine Regulation 59

Scienmag

NOVEMBER 25, 2021

“Understanding the brain in all its complexity requires insights from multiple scales – from genomics, cells and synapses to the whole-organ level. This means working with large amounts of data, and supercomputing is becoming an indispensable tool to tackle the brain,” says Katrin Amunts, Scientific Director of the Human Brain Project (HBP), Director of the […].

Research 91

Research Genome Genomics 91

The Pharma Data

NOVEMBER 25, 2021

PfizerInc. and BioNTech moment blazoned that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) issued a positive opinion on the administration of the companies’COVID-19 vaccine COMIRNATY ® in children 5 to under 12 times of age. The European Commission (EC) will review the CHMP recommendation and is anticipated to make a final decision on a variation to the Tentative Marketing Authorization in the nearfuture.However, the decision will be incontinent

Vaccination 52

Vaccination Vaccine Medicine Trials 52

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This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

Clinical Trials

Scienmag

NOVEMBER 25, 2021

A team of researchers, including scientists from the National Superconducting Cyclotron Laboratory (NSCL) and the Facility for Rare Isotope Beams (FRIB) at Michigan State University (MSU), have solved the case of zirconium-80’s missing mass. Credit: Credit: Facility for Rare Isotope Beams A team of researchers, including scientists from the National Superconducting Cyclotron Laboratory (NSCL) and […].

Scientist 91

Scientist Research 91

The Pharma Data

NOVEMBER 25, 2021

The International Cancer Genome Consortium (ICGC) is further enabling cancer research worldwide by making a massive collection of cancer data available for analysis via Microsoft’s Azure cloud computing platform. Providing secure, controlled access to ICGC genomic and clinical data on Azure will mitigate the need for researchers to obtain massive amounts of storage and computing power within their home institutions, meaning that more researchers will be able to use the data.

Genome 52

Genome Genomics Research Scientist 52

Scienmag

NOVEMBER 25, 2021

HOUSTON – (Nov. 25, 2021) – Seven Earth-sized planets orbit the star TRAPPIST-1 in near-perfect harmony, and U.S. and European researchers have used that harmony to determine how much physical abuse the planets could have withstood in their infancy. Credit: NASA/JPL-Caltech HOUSTON – (Nov. 25, 2021) – Seven Earth-sized planets orbit the star TRAPPIST-1 in […].

Research 89

Research 89

The Pharma Data

NOVEMBER 25, 2021

A combination of two targeted cancer drugs showed unprecedented, “clinically meaningful” activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute. The drug combination, which blocked an overactive cell-growth signaling pathway, shrank tumors by 50% or more in one-third of 45 patients with hard-to-treat high-grade gliomas, including glioblastomas, the most aggre

Drugs 52

Drugs Protein Clinical Trials Clinical Trials 52

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As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

Clinical Supply

Scienmag

NOVEMBER 25, 2021

“We must not only look inside the tumour but also outside of it,” says Héctor Peinado, a researcher at the Spanish National Cancer Research Centre (CNIO). How tumours manipulate their environment to advance is one of the big questions that Peinado has been trying to answer for years. For decades “to fight tumours, researchers focused […].

Research 89

Research 89

Drug Patent Watch

NOVEMBER 25, 2021

Annual Drug Patent Expirations for CHILDREN%27S+ALLEGRA+ALLERGY For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.com. The post New patent expiration for Sanofi Aventis drug CHILDREN’S ALLEGRA ALLERGY appeared first on DrugPatentWatch - Make Better Decisions.

Allergies 52

Allergies Drugs 52

Scienmag

NOVEMBER 25, 2021

New research at the University of Chicago has found differences in immune pathway activation to influenza infection between individuals of European and African genetic ancestry. Many of the genes that were associated with these differences in the immune response to the flu are also enriched among genes that correlate with COVID-19 disease severity. The study […].

Genetics 84

Genetics Immune Response Gene Research 84

Drug Patent Watch

NOVEMBER 25, 2021

Annual Drug Patent Expirations for CHILDREN%27S+ALLEGRA+HIVES For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.com. The post New patent expiration for Sanofi Aventis drug CHILDREN’S ALLEGRA HIVES appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52

Drugs 52

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Scienmag

NOVEMBER 25, 2021

An international research team have discovered a specific type of gut bacteria in bees that can improve memory. An international research team have discovered a specific type of gut bacteria in bees that can improve memory. The study, led by scientists from Jiangnan University, China in collaboration with researchers from Queen Mary University of London and the […].

Bacteria 90

Bacteria Scientist Research 90

BioTech 365

NOVEMBER 25, 2021

SEI Healthcare Releases ERA-EDTA 2021 Congress Summary: Anaemia and CKD Insights SEI Healthcare Releases ERA-EDTA 2021 Congress Summary: Anaemia and CKD Insights An On-Demand Webinar supported by Astellas Pharma and developed in collaboration with the European Renal Association and European … Continue reading →

Development 52

Development 52

Scienmag

NOVEMBER 25, 2021

Scientists have developed new materials for next-generation electronics so tiny that they are not only indistinguishable when closely packed, but they also don’t reflect enough light to show fine details, such as colors, with even the most powerful optical microscopes. Under an optical microscope, carbon nanotubes, for example, look grayish. The inability to distinguish fine […].

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Scientist Development 82

BioPharma Reporter

NOVEMBER 25, 2021

The European Medicines Agencyâs human medicines committee (CHMP) has recommended granting an extension of indication for the Pfizer/BioNTech COVID-19 vaccine to include use in children aged 5 to 11.

Vaccination 52

Vaccination Vaccine Medicine Regulation 52

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The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.

Clinical Trials