Tue.Jun 21, 2022

Mixed results for PTC Duchenne drug put spotlight on EU approval

Bio Pharma Dive

A confirmatory study of PTC Therapeutics’ muscular dystrophy treatment Translarna missed its main goal, although the company highlighted the trial’s overall positive results

Drugs 254

Action needed to reduce e-cigarette use among adolescents to lower lifetime CVD risk

Scienmag

Embargoed until 4 a.m. CT / 5 a.m.

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Pfizer takes stake in Lyme disease partner ahead of key study

Bio Pharma Dive

Valneva will receive $95 million from Pfizer to support development of a vaccine candidate as the French company’s COVID-19 work sputters

Rensselaer researchers make virus-fighting face masks

Scienmag

Rensselaer Polytechnic Institute researchers have developed an accessible way to make N95 face masks not only effective barriers to germs, but on-contact germ killers.

2022 Research: The Rapid Rise of Ocean Freight Visibility

Download this a benchmark study from FourKites and The Journal of Commerce exploring how international shippers’ usage of global supply chain visibility technology has evolved since the onset of global disruptions caused by COVID-19.

Ionis, AstraZeneca claim success for competitor to Alnylam rare disease drug

Bio Pharma Dive

A medicine at the center of a multibillion-dollar alliance between the two companies passed a major test in transthyretin amyloidosis. Full study details were not disclosed, however

Designable spatially coherent wideband radiation and frequency conversion

Scienmag

Components of a typical laser include gain medium, laser pumping energy and resonant optical cavity. The output frequency of most lasers is fixed or within a small range, and it is difficult to generate lasers of some frequencies by common ways.

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Feelings of detachment predict worse mental health outcomes after trauma

Scienmag

Results from the largest prospective study of its kind indicate that for individuals who experience trauma, the presence of dissociation—a profound feeling of detachment from one’s sense of self or surroundings—may indicate a high risk of later developing severe post-traumatic stress, depression, anxiety, physical pain, and social impairment.

Boost your copay program's visibility before it's too late

Bio Pharma Dive

Give your copay program the gift of awareness. GoodRx provides a better way to effective programs

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New WVU program trains next generation of toxicologists to collect, analyze air samples from mining, fracking sites

Scienmag

West Virginia University is launching a toxicology training program that offers students something no other academic program does: experience collecting air samples, identifying the toxicants they contain and determining how those toxicants might harm a community’s health.

A biotech startup launches with $38M to develop a cystic fibrosis gene therapy

Bio Pharma Dive

Carbon Biosciences believes its technology, which is based on parvoviruses, could allow for larger gene delivery and repeat dosing

An Innovative & Creative Problem Solver Approach to Selling in the Medical Device Space

Speaker: Steve Goldstein, Sales Leader

Currently in sales or involved in a business that depends on strong sales results? Join Steve Goldstein, Sales Success Coach, Motivational Speaker and Medical Device Sales Leader from Gold Selling LLC. You will absorb critical strategies to become a trusted partner in greater sales success.

MIT engineers devise a recipe for improving any autonomous robotic system

Scienmag

Autonomous robots have come a long way since the fastidious Roomba. In recent years, artificially intelligent systems have been deployed in self-driving cars, last-mile food delivery, restaurant service, patient screening, hospital cleaning, meal prep, building security, and warehouse packing.

Key Tips for Health Insurance Appeals

Triage Cancer

We’re sharing some key tips to help you receive the care you need if your health insurance company denies coverage for your medical care.

NCCR MARVEL team wins award for ground-breaking work on 2D materials

Scienmag

Investigations into a fascinating class of novel materials that could underpin next-generation electronic and optoelectronic applications and quantum computing has won a team led by Nicola Marzari the inaugural PRACE (Partnership for Advanced Computing in Europe) HPC Excellence Award.

AZ preps FDA filing for $3.6bn amyloidosis drug eplontersen

Pharma Phorum

Armed with new phase 3 data, AstraZeneca is preparing to file for regulatory approval of eplontersen, an antisense drug for one of the complications of the disease transthyretin amyloidosis (ATTR) it licensed from Ionis in a $3.6 billion deal last year.

Mandatory COVID Vaccination Policy Template

The federal government is developing a rule requiring employers with more than 100 employees ensure their workers are vaccinated or produce a negative COVID test weekly before entering the workplace. So, what can your organization do to prepare? Get Paycor’s COVID Vaccination Policy Template to help communicate important details to your employees.

Foodomics: Exploring the biomolecules that will help us get to know our food

Scienmag

University of Strathclyde develops 3D breast cancer screening tool

PharmaTimes

Pre-clinical screening technology could increase cancer test numbers by 50 times

Study highlights undiscovered potential of bacterial compounds and genes linked to colon cancer-related toxin

Scienmag

The last two decades have seen the development of sophisticated computational tools that explore the DNA of bacteria. These tools are on the lookout for interesting metabolites (metabolism-related molecules) that illicit a strong biological reaction.

Diversity Makes Clinical Trial Recruitment Easier and Outcomes Better

BioSpace

Decentralized clinical trials may cost more upfront, but can have huge returns on the back end, according to speakers at Informa Connect’s Decentralized Clinical Trials meeting

University of Illinois researchers derive new theory on behavior of new class of materials

Scienmag

Researchers led by CEE Professor Oscar Lopez-Pamies have derived the governing equations that describe and explain the macroscopic mechanical behavior of elastomers filled with liquid inclusions directly in terms of their microscopic behavior.

The Benefits of an Augmented Consumer Platform Purpose-Built for the Life Sciences

XTalks

WhizAI brings an augmented consumer platform to the life sciences industry to deliver better, smarter and faster business decisions at lower TCO with contextual, AI-powered analytics.

Nature journal publishes UTEP-led pollution study

Scienmag

EL PASO, Texas (June 16, 2022) — Residents of public housing throughout the United States experience higher levels of air pollution, according to an inter-institutional study led by a researcher from The University of Texas at El Paso that appeared in Scientific Reports, one of Nature’s portfolio of journals.

IP is no barrier to COVID vaccine access, says industry

Pharma Phorum

While proponents argue waiving IP on COVID-19 vaccines would better enable low- and middle-income countries to inoculate their populations, the pharma industry has called the proposals “unnecessary and harmful to innovation”.

New insights of how the HIV-1 assembles and incorporates the Env protein

Scienmag

BIRMINGHAM, Ala. Assembly of HIV-1, which causes AIDS, takes place on the inner plasma membrane leaflet of infected cells, a geometric building process that creates hexamers out of trimers of the viral Gag protein, as guided by Gag’s N-terminal matrix domain. Credit: UAB BIRMINGHAM, Ala.

Carbon Biosciences launches with $38m Series A financing round to advance cystic fibrosis gene therapy candidate to clinic

BioPharma Reporter

The developer says it is harnessing parvovirus vectors that can deliver larger gene therapy payloads with enhanced tissue specificity and with minimal neutralizing immunity. Markets & Regulations

Wistar scientists identify novel therapeutic approach to re-activate immune response against tumors

Scienmag

PHILADELPHIA — (June 21, 2022) — Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates.

What Employers Really Look For in Medical Sales Candidates

BioSpace

BioSpace spoke with Jay Johnson, the Director of Talent Acquisition for Orthopedics at Stryker, to find out what it takes to land a job in medical sales

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Oregon State research highlights importance of large wood in streams for land-based animals

Scienmag

CORVALLIS, Ore. Land managers have invested millions of dollars annually since the 1980s to place large pieces of wood back in streams, owing primarily to its importance for fish habitat. But little is known about how large wood in streams impacts birds and land-based animals.

Merck Wins Key FDA Approval for Pediatric Pneumococcal Vaccine

BioSpace

On Wednesday, the FDA approved Merck's pneumococcal 15-valent conjugate vaccine for children 6 weeks through 17 years of age

The secret lives of mites in the skin of our faces

Scienmag

Microscopic mites that live in human pores and mate on our faces at night are becoming such simplified organisms due to their unusual lifestyles that they may soon become one with humans, new research has found.

Opening Day at DIA Meeting: Two Clinical Trial Approaches Join Forces

Imperical Blog

Hello from the 2022 DIA Global Annual Meeting. Not surprisingly, decentralized clinical trial approaches has the spotlight here.

Quantum sensor can detect electromagnetic signals of any frequency

Scienmag

Quantum sensors, which detect the most minute variations in magnetic or electrical fields, have enabled precision measurements in materials science and fundamental physics. But these sensors have only been capable of detecting a few specific frequencies of these fields, limiting their usefulness.

New Research Adds to Momentous Month for Colorectal Cancer Treatment

BioSpace

Researchers at the University of California, San Diego published promising preclinical work on a new combination therapy to treat colon cancer

Where do COVID-19 variants come from?

Scienmag

Survey: most people believe in need for more cancer research

Outsourcing Pharma

A new survey reveals the majority of the general public thinks more cancer research is in order, but many are reluctant to pitch in to the effort financially. Patient centricity