Tue.Nov 09, 2021

article thumbnail

Moderna founder unveils new drug company focused on a different kind of RNA

Bio Pharma Dive

Encouraged by Moderna's success, Flagship Pioneering has been busy creating startups like Alltrna, which launched Tuesday. The biotech is researching how to make medicines from transfer RNA molecules.

RNA 359
article thumbnail

A huge gap exists between HCP medical information needs and pharma

World of DTC Marketing

SUMMARY: Quantitative and qualitative data was gained through surveys with EPG Health’s multi-stakeholder databases (HCP, pharma, and service providers) and interviews conducted with pharma execs by Impatient Health. The objective was to identify new and preferred pathways for the creation and delivery of medical information. Key Findings 1 : HCPS ARE IN CONTROL AND PHARMA KNOWS IT.

Branding 231
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

US pays $1B to nearly double supply of Merck's COVID-19 pill

Bio Pharma Dive

The new agreement raises the financial upside of molnupiravir, which Merck believes could be a $7 billion product in 2022. But Pfizer's rival drug, which has produced seemingly superior efficacy, could affect those projections.

article thumbnail

UNC and Duke Offer Hope for a Universal Coronavirus Antibody Therapy

BioSpace

A research team at the University of North Carolina – Chapel Hill (UNC) and Duke University, in Durham, NC identified an antibody that attacks SARS-CoV-2 and its variants and other types of coronaviruses.

Antibody 124
article thumbnail

The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

article thumbnail

Pfizer again asks FDA to authorize COVID-19 boosters for all adults

Bio Pharma Dive

Agency advisers had opposed a broad booster dose clearance in September, leading the FDA to limit use to older adults and those at high risk of COVID-19.

294
294
article thumbnail

Neuroplast reports successful Phase 1 trial for spinal cord injury stem cell treatment

BioPharma Reporter

Dutch stem cell company Neuroplast has announced positive Phase 1 results for its Neuro-Cells investigational stem cell treatment in patients suffering from Traumatic Spinal Cord Injury (TSCI).

Trials 111

More Trending

article thumbnail

Scotland is world’s first country to greenlight Tagrisso for NSCLC

pharmaphorum

Scotland has given the green light to AstraZeneca’s Tagrisso for restricted use to treat adult patients with non-small cell lung cancer (NSCLC), making it the first country in the world to approve the routine use of the therapy in this setting. The Scottish Medicines Consortium (SMC) has approved Tagrisso (osimertinib) for use within NHS Scotland as a monotherapy for adjuvant treatment after tumour removal in adult patients with stage IB-IIIA NSCLC whose tumours have epidermal growth factor (EGF

HR 104
article thumbnail

CN Bio inks COVID-19 research deal with iiCON

Pharma Times

iiCON’s lead partner LSTM will independently validate CN Bio’s novel lung and lung-liver models

Research 127
article thumbnail

Microbiome discovery could help save kids’ hearing

Scienmag

Bacteria found in children’s upper respiratory systems could help fight chronic middle ear infections, the leading cause of preventable hearing loss and deafness in Indigenous communities. Credit: Australian Department of Health Bacteria found in children’s upper respiratory systems could help fight chronic middle ear infections, the leading cause of preventable hearing loss and deafness in […].

article thumbnail

Sanofi invests $40m in UK gene therapy company Gyroscope Therapeutics

Pharma Times

Funding proceeds will be used to support ongoing trials of Gyroscopes investigational gene therapy GT005

article thumbnail

Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

article thumbnail

Oncology treatment decisions aren’t just based on clinical data

pharmaphorum

Once widely acknowledged as so special that only scientists and clinical specialists need to apply, oncology has become exponentially more clinically targeted and sophisticated over the last decade. Yet how many other therapy areas have market leaders that don’t even have clinical approved indication in that indication? Join this Cerner Enviza webinar, held in partnership with pharmaphorum, for a 45-minute, evidence-backed discussion on the paradoxical question that is “How do I succeed in oncol

article thumbnail

Development of artificial intelligence technology for producing CT images based on MRI

Scienmag

Transcranial focused ultrasound can be used to treat degenerative movement disorders, intractable pain, and mental disorders by delivering ultrasound energy to a specific area of the brain without opening the skull. This treatment must be performed with an image-based technology that can locate the brain lesions. Doctors typically use CT to obtain information about a […].

article thumbnail

Sales coaching: preparing for the new reality in pharma

pharmaphorum

COVID-19 has been a catalyst for a huge amount of change across the pharmaceutical industry, acting as an accelerant for progress in its use of digital technology and prompting a reassessment of how the sales function should work. The pandemic’s first effects on pharma sales were swift and immediate, as lockdowns were put in place and doctors did everything they could to avoid unnecessary face-to-face contact with patients and representatives.

Sales 88
article thumbnail

SwRI developing connected vehicle data exchange platform for Florida Department of Transportation

Scienmag

SAN ANTONIO — Nov. 9, 2021 — Southwest Research Institute is leading an $8 million project to develop a data exchange platform enabling the Florida Department of Transportation (FDOT) to analyze road conditions in real-time and communicate important travel information to the traveling public, state/local government entities, private sector partners and other stakeholders.

article thumbnail

The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

article thumbnail

Moderna and U.S. at Odds Over Vaccine Patent Rights

NY Times

Moderna’s patent application names several employees as the sole inventors of a crucial component of its coronavirus vaccine, excluding three government scientists.

article thumbnail

Announcing the MIT Press Grant Program for Diverse Voices

Scienmag

November 9, 2021 (Cambridge, MA)—In keeping with its mission and longstanding commitment to grow diversity in the ranks of published authors, the MIT Press (MITP) announces the launch of the Grant Program for Diverse Voices. The initiative will expand funding for new work by authors whose voices have been excluded and chronically underrepresented across the arts, […].

89
article thumbnail

COVID-19 Update: Pfizer Requests Broad Booster Authorization, Long COVID Questioned

BioSpace

Pfizer and BioNTech requested the FDA authorize booster shots for their COVID-19 vaccine for all adults 18 years and older, presenting data not available in September.

article thumbnail

First global river database documents 40 years of change

Scienmag

A first-ever database compiling movement of the largest rivers in the world over time could become a crucial tool for urban planners to better understand the deltas that are home to these rivers and a large portion of Earth’s population. Credit: The University of Texas at Austin A first-ever database compiling movement of the largest […].

87
article thumbnail

Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

article thumbnail

Psychedelic Drug Headed to Pivotal Trial in Treatment-Resistant Depression

BioSpace

?The drug reportedly demonstrated significant improvement in patients at its highest dose of 25 mg, particularly in reducing the severity of depressive symptoms after three weeks.

Drugs 98
article thumbnail

Sandia-operated Arctic measurement facility moves, research to continue

Scienmag

ALBUQUERQUE, N.M. — After eight great years of observations and research, a Sandia National Laboratories-operated atmospheric measurement facility moved from Oliktok Point, on the North Slope of Alaska, this summer. The mobile facility will be relocating to the southeastern United States; the exact location is still being decided. Credit: Photo by Brent Peterson/Sandia National Laboratories […].

article thumbnail

Angany Partners with Mass General on Potential Peanut Allergy Vaccine

BioSpace

Angany entered into collaboration for a series of preclinical studies that will evaluate the safety and efficacy of BP/AH-01, Angany’s lead peanut allergy biological candidate.

Allergies 102
article thumbnail

Wash-and-wear sensors

Scienmag

Nov. 9, 2021 — They say you are what you wear. New biosensor technology created at the University of Utah’s College of Engineering makes that even more true. Credit: Dan Hixson/University of Utah College of Engineering Nov. 9, 2021 — They say you are what you wear. New biosensor technology created at the University of […].

article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

NHS staff face spring deadline for mandatory COVID vaccination

Pharma Times

The government is expected to announce that frontline staff in England will have to be fully vaccinated against COVID-19

article thumbnail

Radiotherapy may explain why childhood cancer survivors often develop metabolic disease

Scienmag

Decades after battling childhood cancer, survivors often face a new challenge: cardiometabolic disease. A spectrum of conditions that includes coronary heart disease and diabetes, cardiometabolic disease typically impacts people who are obese, elderly, or insulin resistant. For reasons yet unknown, young, seemingly healthy adults who survived childhood cancer are also at risk.

Insulin 83
article thumbnail

AC Immune Alzheimer’s Drug Reduces Cognitive Decline but Misses Functional Endpoints

BioSpace

AC Immune’s Phase II Lauriet study of investigational anti-Tau monoclonal antibody, semorinemab, in mild-to-moderate Alzheimer’s disease (AD), only met one endpoint.

article thumbnail

Intracellular temperature sensors: Protein complex exhibits temperature-sensitive activity

Scienmag

Osaka, Japan – One degree (Celsius) can make a difference: a team of investigators led by Osaka University has demonstrated regulation of a critical protein complex that occurs only at physiological temperature. Credit: Hiroaki Kubota et al. Osaka, Japan – One degree (Celsius) can make a difference: a team of investigators led by Osaka University […].

Protein 83
article thumbnail

The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.

article thumbnail

UK biotech and University of Birmingham in licensing deal for nasal spray targeting COVID-19

BioPharma Reporter

Birmingham Biotech and the University of Birmingham have signed a licensing agreement for an anti-viral nasal spray against COVID-19.

article thumbnail

Anxiety effectively treated with exercise

Scienmag

Both moderate and strenuous exercise alleviate symptoms of anxiety, even when the disorder is chronic, a study led by researchers at the University of Gothenburg shows. Credit: Photo by Johan Wingbord Both moderate and strenuous exercise alleviate symptoms of anxiety, even when the disorder is chronic, a study led by researchers at the University of […].

article thumbnail

Digitalized HBSM: The Greatest Advantages

Cloudbyz

There are a number of advantages to be gained from the digitalization of many professional processes or structures. Advantages gained from digitalization are certainly not limited to Human Biosample Management (HBSM) or any other applied aspects of the Life Sciences. Considering HBSM in particular, the advantages are numerous, but some of them are more prominent than others in the present and the immediate future.

article thumbnail

Going for gold to reduce antibiotic resistance

Scienmag

Tiny particles of gold could be the new weapon in the fight against bacterial antibiotic resistance, according to research just published. Credit: University of Leeds Tiny particles of gold could be the new weapon in the fight against bacterial antibiotic resistance, according to research just published. Scientists have been investigating the use of gold nanoclusters […].

article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.