Fri.Oct 16, 2020

5 questions ahead of next week's FDA meeting on coronavirus vaccines

Bio Pharma Dive

Normally staid affairs, next Thursday's advisory committee meeting could be historic and set expectations for how the FDA will approach any future vaccine approval

Zeptoseconds: new world record in short time measurement

Scienmag

Physicists from Frankfurt, Hamburg and Berlin track the propagation of light in a molecule Credit: Sven Grundmann, Goethe University Frankfurt FRANKFURT. In 1999, the Egyptian chemist Ahmed Zewail received the Nobel Prize for measuring the speed at which molecules change their shape.

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Early signs of survival benefit raise optimism around a small biotech's ALS drug

Bio Pharma Dive

Newly published data show that, after joining a clinical trial, patients who were given a drug from Amylyx Pharmaceutcials lived a median 6.5 months longer than those who didn't

Pfizer to apply for COVID-19 vaccine EUA after mid-November safety data milestone

BioPharma Reporter

Pfizerâs CEO says the company will apply for Emergency Use Authorisation (EUA) for its COVID-19 vaccine candidate âsoon afterâ a safety milestone is reached in the third week of November. Bio Developments

Gilead's COVID-19 drug doesn't prevent deaths, large WHO study finds

Bio Pharma Dive

The results could weaken the case for widely using Veklury, also known as remdesivir, just as the company is asking for full approval from the FDA

Drugs 209

Boehringer, Yale trial digital tech in heart failure

Pharma Phorum

Patients with heart failure often have a dismal prognosis as the condition usually worsens over time, but a new study aims to see if digital health technologies can improve their prospects.

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Rare diseases, repurposing and the role of AI

Pharma Phorum

In the age of artificial intelligence, no trial data should be going to waste. Findacure’s Rick Thompson looks at how these technologies could bring us closer to treatments for underserved rare diseases. The repurposing of drugs is becoming more common, especially in the field of rare diseases.

Plant genetic engineering to fight ‘hidden hunger’

Scienmag

International research team including University of Göttingen explains advantages of molecular breeding methods Credit: M Qaim More than two billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins.

Domperidone in breastfeeding | Increase milk supply

Druggist

Several factors can impact breast milk supply with common factors including low frequency of breastfeeding, wrong latching by a baby, late start of breastfeeding, use of formula alongside breastfeeding and some drugs.

A promising new tool in the fight against melanoma

Scienmag

An Edith Cowan University (ECU) study has revealed that a key blood marker of cancer could be used to select the most effective treatment for melanoma Credit: Edith Cowan University An Edith Cowan University (ECU) study has revealed that a key blood marker of cancer could be used to select the most effective treatment for […].

Drug May Extend A.L.S. Patients’ Lives by Several Months, Study Finds

NY Times

The two-drug combination invented by college students is one of many potential therapies being tested for this paralyzing fatal condition

Drugs 82

Oncotarget: Induction of phenotypic changes in HER2-postive breast cancer cells

Scienmag

The cover for issue 30 of Oncotarget features Figure 4, “RNAseq results demonstrating differences between normal, cancer, and redirected cells,” by Frank-Kamenetskii, et al.

What does it Take to have a Good Experience of Recruitment in Clinical Research: Malaysia

Journal for Clinical Studies

A staggering number of clinical trials fail to meet recruitment goals, leading to delays, early termination, or inability to draw… Current features Volume 12 Issue 5

Echo from the past makes rice paddies a good home for wetland plants

Scienmag

Geography before human land use impacts how well plant species are retained Credit: Tokyo Metropolitan University Tokyo, Japan – Researchers from Tokyo Metropolitan University studied the biodiversity of wetland plants over time in rice paddies in the Tone River basin, Japan.

Use of Common Meds Tied to Lower Lung Cancer Mortality

The Pharma Data

Professional. Use of Common Meds Tied to Lower Lung Cancer Mortality. FRIDAY, Oct. 16, 2020 — Use of aspirin , metformin , and statins is associated with a lower risk for lung cancer mortality, according to a study published online Sept. 17 in the Journal of Thoracic Oncology. Jihun Kang, M.D.,

Molecular design strategy reveals near infrared-absorbing hydrocarbon

Scienmag

Credit: Norihito Fukui Nagoya University researchers have synthesized a unique molecule with a surprising property: it can absorb near infrared light. The molecule is made only of hydrogen and carbon atoms and offers insights for making organic conductors and batteries.

FDA Requiring Labeling Changes to NSAIDs Warning of Risks in Pregnancy

The Pharma Data

Professional. FDA Requiring Labeling Changes to NSAIDs Warning of Risks in Pregnancy. FRIDAY, Oct. 16, 2020 — The U.S.

Drugs 52

‘Classified knots’: uOttawa researchers create optical framed knots to encode information

Scienmag

Credit: University of Ottawa In a world first, researchers from the University of Ottawa in collaboration with Israeli scientists have been able to create optical framed knots in the laboratory that could potentially be applied in modern technologies.

Young Adult Never Smokers Show Growth in E-Cigarette Use

The Pharma Data

Professional. Young Adult Never Smokers Show Growth in E-Cigarette Use. FRIDAY, Oct.

How is STEM children’s programming prioritizing diversity?

Scienmag

Credit: Royalty-free from PxHere EAST LANSING, Mich. – Children’s television programming not only shapes opinions and preferences, its characters can have positive or negative impacts on childhood aspiration, says a new study from Michigan State University.

Physician’s Briefing Weekly Coronavirus Roundup

The Pharma Data

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Oct. 12 to 16, 2020.

New research comparing HIV medications set to change international recommendations

Scienmag

Credit: University of British Columbia A new study by UBC researchers is set to change international treatment recommendations for people who are newly diagnosed with HIV–an update that could affect nearly two million people per year worldwide.

Global Pharmaceutical Excipients Market Procurement Intelligence Report with COVID-19 Impact Analysis | Global Forecasts, 2020-2024

BioTech 365

LONDON–(BUSINESS WIRE)–#pharmaceuticalexcipients–The Global Pharmaceutical Excipients market will register an incremental spend of about $3 billion, growing at a CAGR of 7.39% during the five-year forecast period.

New study may reveal link to lipids playing a key role in Parkinson’s disease

Scienmag

Employment Disruption-Linked Financial Hardship Found for Female CA Survivors

The Pharma Data

FRIDAY, Oct. 16, 2020 — For female adolescent and young-adult (AYA) cancer survivors, there is a considerable burden of financial hardship related to employment disruption, according to a study published online Oct. 12 in Cancer. Clare Meernik, M.P.H.,

Arctic Ocean sediments reveal permafrost thawing during past climate warming

Scienmag

Credit: Björn Eriksson Sea floor sediments of the Arctic Ocean can help scientists understand how permafrost responds to climate warming. A multidisciplinary team from Stockholm University has found evidence of past permafrost thawing during climate warming events at the end of the last ice age.

Pharmacotherapy, Psychotherapy Combo Best for Bipolar Disorder

The Pharma Data

Professional. Pharmacotherapy, Psychotherapy Combo Best for Bipolar Disorder. FRIDAY, Oct. 16, 2020 — Manualized psychotherapy interventions combined with pharmacotherapy seem beneficial for bipolar disorder , according to a study published online Oct. 14 in JAMA Psychiatry. David J.

Ground-breaking discovery finally proves rain really can move mountains

Scienmag

Credit: Photo by second author Professor Kelin X Whipple. A pioneering technique which captures precisely how mountains bend to the will of raindrops has helped to solve a long-standing scientific enigma.

AHA News: New Mom Faces Life-Threatening Heart Attack Days After Giving Birth

The Pharma Data

FRIDAY, Oct. 16, 2020 (American Heart Association News) — Chanel Davis-Mitchell and her husband, Benji Mitchell, were looking forward to parenthood after the birth of their healthy baby boy, Braxton.

New study highlights the role of risk communication in coping with COVID-19

Scienmag

Credit: Zheng JIN The mental effects of pandemics on people can arise not only from the burden of preventive measures, the fear of contracting and cure but also coping with the exponential deaths.

New Drug Could Extend Life for People With ALS

The Pharma Data

FRIDAY, Oct. 16, 2020 — An experimental drug combination lengthens survival for patients with amyotrophic lateral sclerosis (ALS), new research shows.

Internet connectivity is oxygen for research and development work

Scienmag

Credit: College of ACES, University of Illinois. URBANA, Ill. – Fast and reliable internet access is fundamental for research and development activity around the world. Seamless connectivity is a privilege we often take for granted.

Your Pooch’s Personality Can Change With Age

The Pharma Data

FRIDAY, Oct. 16, 2020 — Just like people, dogs’ personalities change as they age, a new European study suggests.

Membranes for capturing carbon dioxide from the air

Scienmag

Researchers in I2CNER, Kyushu University suggest the potential of the advanced gas separation membranes for CO2 extraction from ambient air Credit: Kyushu University Climate change caused by emissions of greenhouse gases into the atmosphere is a most important issue for our society.