Thu.Apr 15, 2021

article thumbnail

Merck, in latest COVID-19 setback, scraps one drug and pins hopes on another

Bio Pharma Dive

The decision to end development of a medicine acquired in a $425 million deal last November is another disappointment for Merck's coronavirus effort, which once involved multiple drugs and vaccines.

Drugs 321
article thumbnail

The internet enables misinformation on COVID

World of DTC Marketing

QUICK READ: Some deaths will occur during the COVID-19 vaccination rollout, but these deaths would have happened for other reasons and are unrelated to the vaccine. Vaccine-hesitant groups are peddling misinformation online and conspiracy theories aimed at eroding trust in the COVID-19 vaccine are everywhere forcing people to conduct more research. In some instances, vaccine-hesitant activists are manufacturing stories of deaths related to the vaccine that never happened.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Thermo Fisher to buy research contractor PPD in $17B deal

Bio Pharma Dive

The deal values PPD at $47.50 a share, or about 24% over the company's closing price on April 13 — the day before The Wall Street Journal reported word of the planned acquisition.

Research 306
article thumbnail

Moderna to take mRNA flu and HIV vaccines into Phase 1 trials this year

BioPharma Reporter

Moderna will take mRNA flu and HIV vaccines into Phase 1 trials this year, as well as beginning a pivotal Phase 3 study for its cytomegalovirus (CMV) vaccine candidate.

article thumbnail

The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

article thumbnail

GSK stops studies testing closely watched cancer immunotherapy

Bio Pharma Dive

The British pharma will halt enrollment in two studies testing feladilimab alongside Merck's Keytruda, dealing another blow to the company's cancer drug pipeline.

Drugs 285
article thumbnail

Vaccines Won’t Protect Millions of Patients With Weakened Immune Systems

NY Times

Many cannot produce enough infection-fighting cells to fend off the coronavirus. But researchers are testing one therapy that may help: monoclonal antibodies.

Antibody 130

More Trending

article thumbnail

Thermo Fisher Scientific snaps up PPD in $17.4b acquisition deal

Outsourcing Pharma

The science service and technologies firm plans to bring the CRO under its Laboratory Products and Services Segment umbrella after the deal is completed.

article thumbnail

Magic mushroom compound psilocybin shows ‘promise’ in depression

Pharma Times

Researchers from Imperial College London say compound is at least as effective as a leading antidepressant in a therapeutic setting

Research 122
article thumbnail

Japanese-European research team discovers novel genetic mitochondrial disorder

Scienmag

Team of Japanese and European scientists identify a novel genetic mitochondrial disorder by analyzing DNA samples from three distinct families Credit: Fujita Health University DNA ligase proteins, which facilitate the formation of bonds between separate strands of DNA, play critical roles in the replication and maintenance of DNA. The human genome encodes three different DNA […].

Genetics 105
article thumbnail

Pacira Takes ASA to Court in Defense of Non-Opioid Painkiller

BioSpace

With its only approved drug product on the line, Pacira Biosciences is fighting back against what it's calling “misrepresentation of the clinical effectiveness” of its non-opioid pain reliever Exparel.

article thumbnail

Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

article thumbnail

Plant-Based Food Sales + New Wave Foods Shrimp – Xtalks Food Podcast Ep. 6

XTalks

Plant-based food sales shot up in 2020, but will the trend continue? In this episode of the Xtalks Food Podcast, Sydney discusses new data showing that the US market for plant-based foods grew by 27 percent to $7 billion last year, sparking a debate on whether processed foods are actually regarded as healthier if they don’t contain animal products. .

Sales 98
article thumbnail

Monkey-Human Hybrid Research Offers Promise, but Sparks Ethical Debate

BioSpace

According to the researchers, who published their findings online in Cell, certain experiments can't be conducted in humans, making nearly human hybrids a possible solution to this investigational barrier.

Research 112
article thumbnail

Czech Republic swoops for Denmark’s 2.4m unwanted AZ COVID shots

pharmaphorum

The Czech Republic wants to buy around 2.4 million doses of the AstraZeneca/Oxford University vaccine ditched by Denmark, which has said it will stop using it because of concerns about rare blood clotting side-effects. Czech deputy prime minister Jan Hamacek said on twitter that he had instructed the country’s ambassador in Denmark to try to buy the unwanted doses.

article thumbnail

Food and Beverage Companies That Have Gone, Or Announced Plans to Go, IPO in 2021

XTalks

Despite the challenges brought on by the COVID-19 pandemic, the food and beverage industry has remained resilient out of necessity, but also innovation. With restaurants shuttered, an uptick in delivery and takeout orders and a greater focus on health and nutrition, some food and beverage companies found success from the various outcomes of the pandemic — enough success to take their companies public in the form of an initial public offering (IPO).

article thumbnail

The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

article thumbnail

6 Digital Tools at the Center of Healthcare Digitalization [INFOGRAPHIC]

Pharma Marketing Network

Over the last year, we witnessed a massive shift to digital technologies in the health industry – trends that were gradually making their ways suddenly moved into prompt adoption due to the immense limitations brought by the COVID-19 pandemic. Download this infographic and learn which 6 digital tools are at the center of digitalization and how the will influence the future of Pharma marketing in 2021 and beyond.

Sales 98
article thumbnail

US Regulators Recommend Pause on J&J’s COVID-19 Vaccine, But Just as a Precaution

XTalks

Federal authorities in the US have recommended pausing the administration of J&J’s COVID-19 vaccine as half a dozen cases of rare blood clots reported among women who received the vaccine are under investigation. One of the cases was fatal. In a joint statement , the Centers for Disease Control and Prevention (CDC) and the US Food and Drug Administration (FDA) said they are reviewing data involving six reported US cases of a rare and severe type of blood clot in individuals after recei

article thumbnail

While species come and go, their ecosystems persist over millions of years

Scienmag

Credit: Oscar Sanisidro (Universidad de Alcalá de Henares) The study sheds new light upon an ongoing debate among conservation biologists: whether we should conserve sets of endangered species, or whether we should preserve ecosystem functioning, that is, the processes inherent to ecosystems, including those that benefit humans – also called ecosystem services.

98
article thumbnail

AXA partners Microsoft on ‘all-in-one’ digital health platform

pharmaphorum

European insurance giant AXA has stepped up an alliance with Microsoft to develop an international digital health platform on the back of successful pilots in Germany and Italy last year. . The aim is to develop an “all-in-one” digital platform featuring a self-assessment tool, a personalised medical concierge service for appointment booking, and teleconsultations, along with home care service like medicine delivery.

article thumbnail

Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

article thumbnail

AI pinpoints local pollution hotspots using satellite images

Scienmag

Technique could help find sources of heavy air pollution and allow researchers to better study its effects on human health and make more socially just policy decisions Credit: Tongshu Zheng, Duke University DURHAM, N.C. – Researchers at Duke University have developed a method that uses machine learning, satellite imagery and weather data to autonomously find […].

article thumbnail

Mixing COVID-19 vaccines: UK trial adds in Moderna and Novavax vaccines

BioPharma Reporter

A UK study, which has been trialing the combination of Oxford-AstraZeneca and Pfizer vaccine doses, is now extending the program to include Moderna and Novavax vaccines.

article thumbnail

Measuring neutron star squeezability

Scienmag

NICER collaboration, NASA astronaut reveal size of most massive neutron star, highlight Space Station science Credit: NASA / Walt Feimer A team of scientists used a telescope on the International Space Station to measure the size of PSR J0740+6620 (J0740, for short), the most massive known neutron star. NASA’s Neutron star Interior Composition Explorer (NICER) […].

article thumbnail

Vaccines Won’t Protect Millions of Patients With Crippled Immune Systems

NY Times

Many cannot produce enough infection-fighting cells to fend off the coronavirus. But researchers are testing one therapy that may help: monoclonal antibodies.

article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Psychedelic “Magic Mushroom” Compound Shows Promise for Depressive Disorder in Small Study

BioSpace

A small Phase II study published Wednesday in the New England Journal of Medicine suggests psilocybin, a psychedelic compound found in “magic mushrooms,” may be an effective treatment for moderate-to-severe major depressive disorder.

Medicine 102
article thumbnail

A new treatment for rare muscular disease

Scienmag

UC researchers present findings that could give patients with Pompe disease a better quality of life Credit: University of Cincinnati Rare diseases are sometimes the most difficult to treat because of a lack of research and fewer participants to study. An example would be those who have Pompe disease, a genetic condition when a body […].

article thumbnail

Alchemab completes £60m Series A funding to advance novel antibody platform

Pharma Times

The funding will be used to advance Alchemab’s novel platform to identify disease-modifying antibody therapeutics

Antibody 108
article thumbnail

Environmental protection could benefit from ‘micro’ as well as ‘macro’ thinking

Scienmag

Credit: Luke Holman Scientists at the University of Southampton have conducted a study that highlights the importance of studying a full range of organisms when measuring the impact of environmental change – from tiny bacteria, to mighty whales. Researchers at the University’s School of Ocean and Earth Science, working with colleagues at the universities of […].

article thumbnail

The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.

article thumbnail

Abzena Plans $200 Million Manufacturing Biologics Facility in N.C.

BioSpace

Abzena is opening another manufacturing site, its sixth in a global network. This morning, the partner research organization announced it would build a $200 million facility in Sanford, N.C.

article thumbnail

HIV has been had

Scienmag

Credit: Department of Medicinal Chemistry, TMDU Tokyo, Japan – A team of scientists led by the Institute of Biomaterials and Bioengineering at Tokyo Medical and Dental University (TMDU) have created novel molecules that prevent human immunodeficiency virus (HIV) particles from attacking immune cells. This is accomplished by injecting compounds mimicking the protein the virus usually […].

Protein 79
article thumbnail

Research Roundup: UK Variant Not as Lethal as Originally Reported and More

BioSpace

Every week there are numerous scientific studies published. Here’s a look at some of the more interesting ones.

article thumbnail

Oxygen migration enables ferroelectricity on nanoscale

Scienmag

Credit: University of Groningen Hafnium-based thin films, with a thickness of only a few nanometres, show an unconventional form of ferroelectricity. This allows the construction of nanometre-sized memories or logic devices. However, it was not clear how ferroelectricity could occur at this scale. A study that was led by scientists from the University of Groningen […].

article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.