Thu.Feb 25, 2021

Top Moderna executive to leave company later this year

Bio Pharma Dive

Tal Zaks, the biotech's chief medical officer for the past six years, will depart in September after playing a high-profile role in the company's coronavirus vaccine development

Drug side effects should be easier to understand

World of DTC Marketing

SUMMARY: Per the Times, “what if consumers could calculate the benefits and risks of taking a prescription drug as easily as they can gauge the carbohydrates and calories in an Oreo cookie?” ” Drug facts boxes are needed, but the FDA disagrees.

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Former AveXis executives launch gene therapy startup with uncommon targets

Bio Pharma Dive

Sean Nolan and Joe Nolan, former leaders at the Zolgensma developer, are behind Jaguar Gene Therapy, which plans to research treatments for a rare metabolic disease as well as genetically linked autism and diabetes

FDA Approves Third Sarepta Treatment For Duchenne Muscular Dystrophy

BioSpace

The U.S. FDA approved Sarepta Therapeutics’ Amondys 45 (casimersen) for patients with Duchenne muscular dystrophy (DMD) who have a confirmed mutation amenable to exon 45 skipping

Sarepta wins FDA approval of another drug for rare muscular dystrophy

Bio Pharma Dive

Amondys 45 is now cleared for the estimated 8% of Duchenne patients eligible for treatment. Like other Sarepta drugs, it comes with a high price tag and its clinical benefits haven't been confirmed

Tumors and centrosomes: Researchers receive grant to investigate cancer evolution

Scienmag

Credit: Virginia Tech Unlike many of us during the COVID-19 pandemic, biological cells are not isolated from the outside world. Chemical variations, intercellular activity, and other microenvironmental factors impact cell survival.

Merck to buy autoimmune drugmaker for $2B

Bio Pharma Dive

The deal, which values Pandion Therapeutics at a more than 100% premium, would hand Merck a drug in early-stage testing for ulcerative colitis and lupus

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Altimmune begins trial of nasal vaccine for COVID-19

Pharma Phorum

Pfizer/BioNTech’s mRNA vaccine against COVID is a technical marvel – but the ultra-cool temperatures required for storage and stability has been tricky to handle.

64 human genomes as new reference for global genetic diversity

Scienmag

Publication in Science Credit: David Porubsky, University of Washington In 2001, the International Human Genome Sequencing Consortium announced the first draft of the human genome reference sequence.

Field Trip Health’s New Psilocybin Research Facility Probes the Secrets of Shrooms

BioSpace

The world’s first legal research and cultivation facility dedicated exclusively to psilocybin-producing mushrooms (called shrooms or magic mushrooms) and other plant-based psychedelics recently opened in Jamaica

Landmark study details sequencing of 64 full human genomes to better capture genetic diversity

Scienmag

Scott Devine, PhD 64 human genomes sequenced will serve as new reference for genetic variation and predisposition to human diseases Credit: NIH Researchers at the University of Maryland School of Medicine (UMSOM) co-authored a study, published today in the journal Science, that details the sequencing of 64 full human genomes.

Roivant Dives Deeper into AI with $450 Million Buy of Silicon Therapeutics

BioSpace

The Silicon Therapeutics acquisition is designed to complement Roivant’s targeted protein degradation platform

Building a better future for people with rare diseases in all four UK nations

Pharma Phorum

How has rare disease care changed over the last few years? And what might we expect from the next five? We attended the Rare Disease Day Virtual Parliamentary Event to find out.

Nuclear physicists on the hunt for squeezed protons

Scienmag

Nuclear physicists crank up the energy to put the squeeze on the proton and its quarks Credit: DOE’s Jefferson Lab While protons populate the nucleus of every atom in the universe, sometimes they can be squeezed into a smaller size and slip out of the nucleus for a romp on their own.

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AstraZeneca, Amgen Breathing Easier with Optimistic Phase III Asthma Drug Results

BioSpace

After announcing a successful primary endpoint in November, AstraZeneca and Amgen presented the full data on their severe asthma antibody candidate on Friday

Scientists use Doppler to peer inside cells

Scienmag

Process leads to Scientists use Doppler to peer inside cells, leading to better, faster diagnoses and treatments of infection Credit: Purdue University photo/Rebecca McElhoe WEST LAFAYETTE, Ind. — Doppler radar improves lives by peeking inside air masses to predict the weather.

German program using whole genome sequencing to diagnose rare diseases and cancer risk

BioPharma Reporter

A program at the University Hospital of TÃbingen is the first in Germany to use whole genome sequencing (WGS) to improve the diagnosis of rare diseases and hereditary cancers. Markets & Regulations

Lethal house lures reduce incidence of malaria in children

Scienmag

Credit: Daniel Lesher, Penn State UNIVERSITY PARK, Pa. — A new type of housing modification can reduce malaria incidence among children by around 40-50%, according to an international team of researchers.

Research Roundup: Compound Reverses ALS Nerve Damage and More

BioSpace

Every week there are numerous scientific studies published. Here’s a look at some of the more interesting ones

Smaller plates help reduce food waste in campus dining halls

Scienmag

Credit: University of Illinois. URBANA, Ill. – Food waste is a major problem in the U.S., and young adults are among the worst culprits. Many of them attend college or university and live on campus, making dining halls a prime target for waste reduction efforts.

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The Coronavirus Is Plotting a Comeback. Here’s Our Chance to Stop It for Good.

NY Times

Many scientists are expecting another rise in infections. But this time the surge will be blunted by vaccines and, hopefully, widespread caution. By summer, Americans may be looking at a return to normal life.

A cat of all trades

Scienmag

Credit: Photo by Brutus Östling Large carnivores are generally sensitive to ecosystem changes because their specialized diet and position at the top of the trophic pyramid is associated with small population sizes.

Cloudbyz Is now an ISO/IEC 27001:2013 Certified Company

Cloudbyz

WARRENVILLE, Ill. , Feb. 23, 2021 /PRNewswire/ — Cloudbyz , a pioneer in cloud-based SaaS products for Clinical Trial Management, Pharmacovigilance and Project Portfolio Management, has recently been certified with ISO/IEC 27001:2013.

Risk genes in schizophrenia – their importance in choosing appropriate antipsychotic drug

Scienmag

This article by Dr. Felix-Martin Werner and Prof. Rafael Coveñas is published in Current Pharmaceutical Design, 2021 Credit: Dr. Felix-Martin Werner, Dr. Rafael Coveñas Dr. Felix-Martin Werner, working at the Euro Academy Pößneck in Germany and Prof.

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Gene and Cell Therapies in CNS Disorders: Miracle Cure? Opportunities Galore!

Delveinsight

CNS disorders are a wide-ranging set of disorders in which the brain loses its normal functioning, limiting everyday ability to function. These may arise from various reasons-some are inherited, some result from damage, and some from infections.

Study: Bladder cancer is more advanced in South Texas

Scienmag

Credit: The University of Texas Health Science Center at San Antonio Bladder cancer is more aggressive and more advanced in South Texas residents ­than in many parts of the country, a study by the Mays Cancer Center, home to UT Health San Antonio MD Anderson, indicates.

Streetsboro OH Dentist Anxiety-Free Same-Day Sedation Implant Services Updated

BioTech 365

Streetsboro OH Dentist Anxiety-Free Same-Day Sedation Implant Services Updated Streetsboro OH Dentist Anxiety-Free Same-Day Sedation Implant Services Updated Streetsboro, OH Signature Smiles Dental has updated its range of same-day sedation services.

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Heavy rain affects object detection by autonomous vehicle LiDAR sensors

Scienmag

West Lake Hills TX Zoom Teeth Whitening Stain Removal Expert Services Launched

BioTech 365

West Lake Hills TX Zoom Teeth Whitening Stain Removal Expert Services Launched West Lake Hills TX Zoom Teeth Whitening Stain Removal Expert Services Launched Westlake Hills Dental Arts, a dental office in West Lake Hills, TX, launched a range of … Continue reading → GlobeNewswire

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Repetitive compression of limbs appears to aid recovery from deadly brain bleeds

Scienmag

Credit: Kim Ratliff, Augusta University photographer AUGUSTA, Ga. 25, 2021) – Scientists want to know more about how an inexpensive, low-risk treatment may improve recovery from the most deadly type of stroke.

Invisalign Augusta ME Orthodontist Updates Clear Aligners Invisible Braces

BioTech 365

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New saliva tests rolled-out to hospital staff to cut COVID transmission rates

Scienmag

Credit: Earlham Institute (EI) Frontline staff at Norfolk and Norwich University Hospitals (NNUH) are among the first in the country to benefit from the rollout of more accurate saliva tests in a bid to curb Covid transmission rates.

New Sales Directors at Romaco in Cologne, Bologna and Karlsruhe

Pharma Mirror

Borja Guerra has been appointed new Sales & Service Director of Romaco Kilian in Cologne. The Romaco facilities in Bologna and Karlsruhe likewise have new Sales Directors: Massimiliano Cesarini and Ralph Augenstein. Romaco Kilian GmbH in Cologne has acquired a new Sales & Service Director.

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Researchers identify drugs with potential to stop plaque buildup in arteries

Scienmag

Findings could lead to better treatments for cardiovascular disease–the second leading cause of death in Canada.

Merck Animal Health Completes Acquisition of Poultry Sense Limited

BioTech 365

Merck Animal Health Completes Acquisition of Poultry Sense Limited Merck Animal Health Completes Acquisition of Poultry Sense Limited Proprietary Technology Enhances Health and Environmental Monitoring Solutions for Poultry Producers MADISON, N.J.–(BUSINESS

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Ultra-high-resolution X-ray imaging of 3D objects

Scienmag

New flexible X-ray sensor suitable for next-generation medical and industrial applications Credit: Ou Xiangyu X-ray imaging is widely used in areas such as healthcare and forensic science, but existing X-ray machines are unable to capture curved three-dimensional (3D) objects at high resolution, and they are also relatively expensive.

Quanterix’ Kevin Hrusovsky to Present at the Cowen 41st Annual Health Care Conference on March 3 and Appear on the Feb. 26 Episode of the Health Care Rounds Podcast

BioTech 365

Quanterix’ Kevin Hrusovsky to Present at the Cowen 41st Annual Health Care Conference on March 3 and Appear on the Feb. 26 Episode of the Health Care Rounds Podcast Quanterix’ Kevin Hrusovsky to Present at the Cowen 41st Annual Health … Continue reading → Business Wire

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