Wed.Oct 21, 2020

Biogen is running out of safety nets

Bio Pharma Dive

Third quarter earnings underscore just how vital it is that Biogen secure approval of its experimental Alzheimer's drug, given the challenges elsewhere in its business

Drugs 225

10 Trends for online health seekers

World of DTC Marketing

IN SUMMARY: Online health seekers are using the Internet differently since the pandemic. Treatment options are researched more, and people are using, but not relying, on social media to gather information on what’s best for THEM.

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CRISPR Therapeutics reports remissions, one death in cancer cell therapy study

Bio Pharma Dive

The biotech is one of several attempting to develop "off-the-shelf "CAR-T therapies. While trial results show potential, high-dose treatment was paused following a patient's death

Trials 220

IBM and Pfizer Believe Machine Learning Can Predict Alzheimer’s Risk

BioSpace

Researchers with Pfizer and IBM developed an artificial intelligence (AI) model that they claim can predict eventual onset of Alzheimer’s disease with 71% accuracy based on a language sample. They published the research today in The Lancet eClinicalMedicine

An Indiana startup aims to boost the US drug manufacturing push

Bio Pharma Dive

Incog BioPharma Services has become the latest entity to sprout up as part of a concerted U.S. effort to onshore production of pharmaceuticals

Neural Dust: Millimeter-Sized Brain Stimulators

BioSpace

Bolstered by studies in rodents, iota Biosciences advances towards their vision

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Roche Pays Atea $350 Million Up Front to Partner on COVID-19 Antiviral Drug

BioSpace

Roche and Atea Pharmaceuticals are partnering to develop, manufacture and distribute AT-527, Atea’s experimental antiviral drug against COVID-19

Patients and physicians brace for flu season amid COVID-19

Bio Pharma Dive

ZS surveyed more than 500 patients and 500 physicians to gather their perspectives on COVID-19's potential impact on flu vaccination rates

Moderna Fully Enrolls 30,000-Person COVID-19 Vaccine Trial, Boosts Minority Participation

BioSpace

Moderna has fully enrolled its late-stage coronavirus disease 2019 (COVID-19) vaccine trial by hitting its target of 30,000 participants. More than one-third of this cohort includes minority participants

Purdue, reaching $8B settlement with US, pleads guilty to charges over opioid sales

Bio Pharma Dive

Under a deal reached with the Department of Justice, Purdue faces fines and a forfeiture worth more than $5 billion — the largest penalties ever for a drug company

Sales 130

Best Toenail Fungus Treatment Products

Druggist

Fungal nail infection is a common condition, which usually affects toenails. The main products used for toenail fungus treatment are available in most pharmacies, supermarkets and perhaps with the best range of products found online.

Technology shines the light on ovarian cancer treatments

Scienmag

Credit: David Nolte/Purdue University WEST LAFAYETTE, Ind. – Scientists estimate that nearly 60% of all cancer patients do not respond effectively to chemotherapy treatments. Even worse – many of those same patients experience toxic and sometimes deadly side effects.

FDA Grants Full Approval to Remdesivir for COVID-19

BioSpace

Shares of Gilead Sciences are jumping in aftermarket trading following full approval for Veklury (remdesivir) as a treatment for COVID-19. The approval marks the first drug approved by the U.S. Food and Drug Administration as a treatment for the novel coronavirus

Drugs 85

Vanilla cultivation under trees promotes pest regulation

Scienmag

Research team led by University of Göttingen investigates agroforestry systems in Madagascar Credit: Annemarie Wurz The cultivation of vanilla in Madagascar provides a good income for small-holder farmers, but without trees and bushes the plantations can lack biodiversity.

Rep. Schakowsky (D-IL) Gets an A+ on Drug Prices in Congressional Report Card

Pharmacy Checkers

This post was originally published on Prescription Justice. The highest score in the Prescription Justice Congressional Report Card on Drug Prices – 100 – goes to Representative Jan Schakowsky (D-IL) , with a grade of A+. The only other A+ in the House goes to Rep.

Drugs 58

Hidden states of the COVID-19 spike protein

Scienmag

Computational and experimental research by joint UC Berkeley-ITU team seeks unknown vulnerabilities of coronavirus Credit: Ahmet Yildiz, University of California, Berkeleky; Mert Gur, Istanbul Technical University The virus wreaking havoc on our lives is an efficient infection machine.

FDA Deputy Commissioner Discusses Modernization Strategies for Data and Trials

BioSpace

After reviewing its mid-pandemic performance, it became clear that its greatest challenge is around the handling of data, according to Amy P. Abernethy, M.D., principal deputy commissioner, FDA, speaking at the recent Demy-Colton Virtual Salon, the “Fusion of Technologies

Thymoquinone induces apoptosis & DNA damage in 5-Fluorouracil-resistant colorectal cancer

Scienmag

Volume 11, Issue 31 from @Oncotarget reported that TQ decreased the expression levels of colorectal stem cell markers CD44 and Epithelial Cell Adhesion Molecule Ep CAM and proliferation marker Ki67 in colonospheres derived from both cell lines and… Credit: Correspondence to – Hala Gali-Muhtasib – amro@aub.edu.lb

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New patent for Sarepta Theraps drug EXONDYS 51

Drug Patent Watch

Annual Drug Patent Expirations for EXONDYS+51 Exondys 51 is a drug marketed by Sarepta Theraps Inc and is included in one NDA. It is available from one supplier. There are…. The post New patent for Sarepta Theraps drug EXONDYS 51 appeared first on DrugPatentWatch - Make Better Decisions.

Covid-19 interventions can cut virus infections, severe outcomes, and healthcare needs

Scienmag

Credit: Rob Felt, Georgia Tech Non-pharmaceutical interventions such as voluntary shelter-in-place, quarantines, and other steps taken to control the SARS-CoV-2 virus can reduce the peak number of infections, daily infection rates, cumulative infections, and overall deaths, a new study published in the journal PLOS ONE has found.

How the Biopharma Industry is Tackling the Opioid Crisis

BioSpace

Many drug makers are investing in new science and hope to transition pain therapy approaches away from synthetic opioids. Biospace has tracked a few key alternative therapeutic candidates

Drugs 80

Social isolation exacerbates the situation of school bullying victims

Scienmag

Credit: Universidad de Córdoba (Spain) In school bullying, there are people who are chronic victims. The acts of aggression that they experience are not limited to a particular moment or period of time, but rather part of a sustained process over a long period of time.

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Trends in Physician Voting Practices in California, New York, and Texas, 2006-2018

JAMA Internal Medicine

This cohort study investigates physician voter participation, voter registration, and voter turnout from 2006 through 2018 in 3 states with the largest number of physicians

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Five key factors for improving team learning in distance education

Scienmag

The UOC is designing a course that overcomes the challenges of collaborative learning online Credit: UOC Distance studying and working is on the rise and, especially now with the constant threat of lockdown, learning how to master it more pressing than ever.

RA Capital Closes $461 Million Investment Fund Aimed at Life Sciences Companies

BioSpace

The new fund, RA Capital Nexus Fund II, will serve as a companion fund to RA’s Nexus I fund, which closed last year with approximately $300 million in capital

University of Miami joins Global Cyberinfrastucture Network as a scientific partner

Scienmag

Collaboration with Brazilian researchers will focus on sharing datasets in real time for improved weather and climate change predictions Credit: Diana Udel, UM Rosenstiel School of Marine and Atmospheric Science The University of Miami’s Institute for Data Science and Computing (IDSC) has joined FABRIC, the advanced U.S.

United Therapeutics Highlights Poster Presentations from the Recent CHEST 2020 Meeting

The Pharma Data

Clinical study data suggests Tyvaso® improved forced vital capacity, an important measure of lung function, in patients with pulmonary hypertension associated with interstitial lung disease. Seven poster presentations are available at ir.unither.com. SILVER SPRING, Md.

Tracking the SARS-CoV-2 virus with genome sequencing

Scienmag

Using next generation sequencing on SARS-CoV-2 will help accurately diagnose the novel coronavirus, identify mutations and track its history.

BD Announces Executive Leadership Appointments

The Pharma Data

Patrick Kaltenbach appointed chief technology officer. Dave Hickey promoted to president, Life Sciences segment. FRANKLIN LAKES, N.J. ,

Novel bioresorbable, tissue-healing surgical device approved by FDA

Scienmag

Acuitive Technologies’ CITRELOCK orthopedic surgery system based on biomaterial invented by Penn State’s Jian Yang and Northwestern University’s Guillermo Ameer Credit: Acuitive Technologies UNIVERSITY PARK, Pa.

Agios to Webcast Conference Call of Third Quarter 2020 Financial Results on November 5, 2020

The Pharma Data

CAMBRIDGE, Mass., 22, 2020 (GLOBE NEWSWIRE) — Agios Pharmaceuticals, Inc.

How fear encourages physical distancing during pandemic

Scienmag

Study finds negatively presented information and ‘Mr.

Athenex, Inc. to Report Third Quarter 2020 Earnings Results on November 5, 2020

The Pharma Data

BUFFALO, N.Y., 22, 2020 (GLOBE NEWSWIRE) — Athenex, Inc.

Genome sequencing shows climate barrier to spread of Africanized bees

Scienmag

Added diversity may be useful for breeding bees Credit: Erin Calfee Since the 1950s, “Africanized” honeybees have spread north and south across the Americas until apparently coming to a halt in California and northern Argentina.