Sat.Jun 11, 2022

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Vertex, CRISPR strengthen case for pioneering gene-editing treatment

Bio Pharma Dive

Positive data from 75 patients with either sickle cell disease or beta thalassemia keep the companies’ therapy on track to become the first CRISPR-based treatment submitted to drug regulators, possibly by the end of the year.

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Building up new data-storage memory

Scienmag

Tokyo, Japan – Scientists from the Institute of Industrial Science at The University of Tokyo fabricated three-dimensional vertically formed field-effect transistors to produce high-density data storage devices by ferroelectric gate insulator and atomic-layer-deposited oxide semiconductor channel. Furthermore, by using antiferroelectric instead of ferroelectric, they found that only a tiny net charge was required to erase […].

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Directly wireless communication of human minds via non-invasive brain-computer-metasurface platform

Scienmag

Recently, coding metasurfaces, incorporating active components, have enabled real-time and programmable controls over EM functionalities, which used to be static or quite limited in conventional passive counterparts. However, these kinds of metasurface still require the manual operations. To directly inspect and distinguish the human’s will, the brain-computer interface (BCI) is presented to establish the communication […].

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Rapid whole genome sequencing improves diagnosis in critically ill infants on a national scale

Scienmag

Vienna, Austria: Children who are born severely ill or who develop serious illness in the first few weeks of life are often difficult to diagnose, with considerable implications for their short and longer-term care. But whole genome sequencing1 (WGS), carried out rapidly, can provide an accurate diagnosis and therefore lead to improvements in their clinical […].

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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One step closer to moving things with our thoughts

Scienmag

Metamaterials have attracted extensive attention from many fields due to their extraordinary physical properties. It has provided researchers with a new concept of designing artificial materials, bringing vigor and vitality to advanced functional materials. As the two-dimensional counterpart to metamaterials, metasurfaces have unprecedented freedom in manipulating EM waves.

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Study finds strong association between prediabetes and heart attack risk

Scienmag

Prediabetes appears to be a strong independent risk factor for heart attacks, according to a new study presented Saturday, June 11 at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. Prediabetes is a condition in which blood glucose levels are higher than normal, but not high enough to be considered diabetes. People with […].

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Maintaining normal weight early in life may help prevent male infertility

Scienmag

New research suggests that more careful control of body weight in childhood and adolescence could help prevent male infertility later in life. The researchers will present their findings on Saturday, June 11 at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. The study finds that children and adolescents with overweight or obesity, or […].

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AI can be used to identify benign thyroid nodules and reduce unnecessary biopsies

Scienmag

Artificial intelligence (AI) can be used to identify thyroid nodules seen on thyroid ultrasound that are very unlikely to be cancerous, reducing a large number of unnecessary biopsies, according to a new study being presented Saturday at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. Thyroid nodules are very common. Fine needle aspiration […].

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Commercial T cell test reveals factors correlated with diminished T cell responses to SARS-CoV-2 in clinical study subjects

Scienmag

Washington, D.C. – June 11, 2022 – T cell testing using a commercial T cell test, QuantiFERON SARS-CoV-2 RUO, offers insight into the immune response to infection and vaccination of patients with COVID-19 and suggests that age and time from infection are significant factors related to the magnitude of cell-mediated immune (CMI) responses to COVID-19.

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Chemicals in personal care products cause harmful effects in breast cancer cells from Black women

Scienmag

Chemicals called parabens, which are found in widely used hair and personal care products, cause harmful effects in breast cancer cells from Black women, according to a new study being presented Sunday at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. One in eight women in the United States will get breast cancer […].

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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COVID-19 vaccination appears to be safe for patients treated for hypothyroidism

Scienmag

Inactivated and mRNA COVID-19 vaccines appear to be safe for patients treated for hypothyroidism, according to a new study being presented at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. The study found these vaccines do not cause significant fluctuations in thyroid function and are not associated with increased risks of emergency department […].

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Adult growth hormone deficiency increases medical costs, risk of additional health conditions

Scienmag

Growth hormone deficiency (GHD) among adults is associated with greater medical costs and an increased rate of other health conditions compared with those without GHD, according to industry-sponsored research being presented Monday at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. GHD is a rare disorder linked to poor quality of life and […].

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Teens ate less ultra-processed food consumption during pandemic, reversing trend of three decades

Scienmag

For the first time in the last 30 years, the consumption of ultra-processed foods among teenagers in the United States declined during the COVID-19 pandemic, according to a new study presented at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. The decline in junk food consumption among teens took place in the wake […].

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Bias may play a role in underdiagnoses of prediabetes

Scienmag

The accurate diagnosis of prediabetes in the primary care setting might depend on a patient’s age, BMI, gender, race and certain comorbidities, according to research being presented at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. Prediabetes is reversible through medications and lifestyle changes, and a correct and timely diagnosis might help prevent […].

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Probiotic bacteria may enhance tamoxifen effectiveness in treatment of ER+ breast cancer

Scienmag

Probiotic bacteria may enhance anti-cancer activities of the breast cancer drug tamoxifen and other endocrine-targeted therapies, which could help reduce the risk of estrogen receptive positive (ER+) breast cancer, suggests a new study presented Monday at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. While the majority of bacteria in the body is […].

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Drinking coffee does not hinder the absorption of liquid thyroid medication

Scienmag

Although current product labels and treatment guidelines recommend that patients take thyroid hormone replacement therapy on an empty stomach, new research suggests drinking coffee does not affect the absorption of a liquid formulation of levothyroxine (LT4). A new study conducted by Vertice Pharma confirms the absorption of an oral levothyroxine sodium solution (Thyquidity® 100mg/ 5mL) […].

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Moderation may disrupt addictive nature of wireless mobile devices and adverse health outcomes

Scienmag

Encouraging moderation, balance and real-life engagement coupled with education may combat the overuse of wireless mobile devices and subsequent adverse health outcomes, according to research being presented Sunday at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga. Nidhi Gupta, M.D., founder of KAP Pediatric Endocrinology in Franklin, Tenn., aimed to review existing data […].