Mon.Apr 19, 2021

Positive data in hand, TG Therapeutics readies MS drug for FDA review

Bio Pharma Dive

If approved, TG's drug would join Roche's fast-selling Ocrevus and Novartis' newer entrant Kesimpta as one of a newer class of multiple sclerosis therapies

Drugs 232

The danger of COVID conspiracy theorists

World of DTC Marketing

QUICK READ: At times, the public health response to coronavirus (COVID-19) has been scary, characterized by antimask behavior, antivaccine beliefs, conspiracy theories around the development of the vaccine, and a general belief that even COVID numbers are false.

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A startup raises $336M to make a better antibody drug for COVID-19

Bio Pharma Dive

Adagio Therapeutics, a well-financed spinout of antibody developer Adimab, could challenge Regeneron and Eli Lilly if its drug candidate proves protective in clinical tests

Learning about system stability from ants

Scienmag

Real World Data: How to leverage transformative data sources to reduce study costs, evaluate real world clinical outcomes

Bio Pharma Dive

Real World Data provides increasingly significant value throughout all stages of a product's lifecycle. The time to embrace it is now. Here's why

UK Vaccine Taskforce head lifts lid on Novavax deal

Pharma Phorum

The UK’s unique offering as a life sciences research hub helped convince US biotech Novavax to develop its COVID-19 jab there, according to the head of the country’s Vaccines Taskforce. .

Canine cancer research startup impacts treatment in humans

Outsourcing Pharma

One Healthâs FidoCure is using genomics and AI technology to develop precision oncological treatments, and the work is benefiting human cancer research. Clinical Development

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New advice on COVID-19 vaccination for pregnant women in UK

Pharma Times

JCVI advises pregnant women in the UK be offered COVID-19 vaccination at the same time as the rest of the population

Surprising ionic and flow behaviors with functionalized nanochannels

Scienmag

UMD engineering research team demonstrates overscreening, flow reversal in nanosystems Credit: T. Pial et al., ACS Nano, 2021, DOI: 10.1021/acsnano.0c09248 Nanochannels have important applications in biomedicine, sensing, and many other fields.

SparingVision to buy GAMUT and potential Luxturna eye gene therapy competitor

Pharma Phorum

French genomic medicines firm SparingVision has agreed to buy GAMUT Therapeutics, a biotech specialising in gene therapies for inherited eye diseases such as retinitis pigmentosa (RP) that could compete against Roche/Spark’s Luxturna in a wider patient group. .

Tiny implantable tool for light-sheet imaging of brain activity

Scienmag

Researchers used nanophotonic technology to develop a brain-implantable tool that can aid in the optical imaging of brain activity Credit: Sacher et al., doi 10.1117/1.NPh.8.2.025003.

Amgen Awarded Breakthrough Designation for Acquired Cancer Antibody Drug

BioSpace

One month after snapping up Five Prime Therapeutics and its Phase III ready anti-FGFR2b antibody bemarituzumab for $1.9 billion, Amgen announced the U.S. FDA awarded Breakthrough Therapy Designation to the asset as a first-line treatment for certain types of gastric cancer

Shedding light on the long and the short of plant growth

Scienmag

Credit: John Innes Centre What keeps some plants squatting close to the soil while others – even those closely related – reach high for the skies?

Phico Therapeutics gains £13.1m grant to advance antibacterial therapy

Pharma Times

SASPject PT3.9 is designed for the treatment of hospital infections caused by Pseudomonas aeruginosa

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Selective mRNA degradation via autophagy: A novel role for autophagy in gene regulation

Scienmag

Credit: Tokyo Tech Optimal cell function requires a fine balance between the synthesis and degradation of biomolecules.

NICE unveils five year plan promising faster access to medicines

Pharma Phorum

NICE has included proposals to speed up evaluations and focus on new technology such as digital health in a new strategy to provide faster access to new medical treatments and innovations. .

Understanding spoilage and quality issues may improve American artisan cheesemaking industry

Scienmag

Top concerns of artisan cheesemakers are examined in new research in the Journal of Dairy Science® Credit: Refer to caption Philadelphia, April 20, 2021 – American artisan cheese has become increasingly popular over the past few decades.

Axion BioSystems Announces Formation of Scientific Advisory Board

BioTech 365

Rock glaciers will slow Himalayan ice melt

Scienmag

Credit: Stephan Harrison Some Himalayan glaciers are more resilient to global warming than previously predicted, new research suggests.

Prestige Biopharma’s New Vaccine Production Centre for Infectious Diseases Including COVID-19

BioTech 365

Designing healthy diets – with computer analysis

Scienmag

Credit: Creative Commons A new mathematical model for the interaction of bacteria in the gut could help design new probiotics and specially tailored diets to prevent diseases. The research, from Chalmers University of Technology in Sweden, was recently published in the journal PNAS.

GenSight Biologics Reports Cash Position as of March 31, 2021 and Provides Operational Update

BioTech 365

52

ETRI successfully tests AR services on subway

Scienmag

A joint research project with UK using Giga mobile backhaul network; AR demonstration held on Seoul Subway Line No. 8 with 1.9

Teen Covid-19 survivor returns to Cohen Children’s to thank the doctor who saved her life

BioTech 365

Teen Covid-19 survivor returns to Cohen Children’s to thank the doctor who saved her life Teen Covid-19 survivor returns to Cohen Children’s to thank the doctor who saved her life NEW HYDE PARK, N.Y.–(BUSINESS

Federal policy to reduce deaths from sepsis was mostly ineffective

Scienmag

Repeat: PeakBirch Appoints Seasoned Cannabis Entrepreneur Kiran Sidhu as New Director and Adopts a New RSU Plan and Stock Option Plan

BioTech 365

Repeat: PeakBirch Appoints Seasoned Cannabis Entrepreneur Kiran Sidhu as New Director and Adopts a New RSU Plan and Stock Option Plan Repeat: PeakBirch Appoints Seasoned Cannabis Entrepreneur Kiran Sidhu as New Director and Adopts a New RSU Plan and Stock … Continue reading → Business Wire

52

MIPT and Harvard researchers grow stem cells to cure glaucoma

Scienmag

Credit: Molecular Therapy – Methods and Clinical Development A joint research carried out by MIPT scientists and Harvard researchers have presented retinal cells that can integrate into the retina.

Incyte and MorphoSys Announce First Patient Dosed in Phase 3 inMIND Study Evaluating the Addition of Tafasitamab to Lenalidomide and Rituximab in Relapsed or Refractory Follicular or Marginal Zone Lymphoma

BioTech 365

Incyte and MorphoSys Announce First Patient Dosed in Phase 3 inMIND Study Evaluating the Addition of Tafasitamab to Lenalidomide and Rituximab in Relapsed or Refractory Follicular or Marginal Zone Lymphoma Incyte and MorphoSys Announce First Patient Dosed in Phase 3 … Continue reading → Business Wire

52

Archaeological data demand new approaches to biodiversity conservation

Scienmag

Credit: Erle Ellis Professor Nicole Boivin, Director of the Department of Archaeology at the Max Planck Institute for the Science of Human History in Jena, Germany, is part of an international initiative to examine the implications of past land use for contemporary conservation efforts.

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Arena Pharmaceuticals Releases Second Annual Environmental, Social and Governance (ESG) Report

BioTech 365

52

Stanford researchers use AI to empower environmental regulators

Scienmag

Credit: Nina Brooks Like superheroes capable of seeing through obstacles, environmental regulators may soon wield the power of all-seeing eyes that can identify violators anywhere at any time, according to a new Stanford University-led study.

The Sonic Fund II, L.P. Files Definitive Proxy Statement and Sends Letter to Stockholders of Adverum Biotechnologies, Inc.

BioTech 365

The Sonic Fund II, L.P. Files Definitive Proxy Statement and Sends Letter to Stockholders of Adverum Biotechnologies, Inc. The Sonic Fund II, L.P. Files Definitive Proxy Statement and Sends Letter to Stockholders of Adverum Biotechnologies, Inc.

52

Can cirrhosis of the liver be treated with faeces transplantation?

Scienmag

Researchers from Aarhus University and Aarhus University Hospital replace sick intestinal bacteria with intestinal bacteria from healthy donors in a treatment intended to help patients with cirrhosis of the liver. The Novo Nordisk Foundation supports the Credit: Simon Mark Dahl Baumwall.

Brooklyn ImmunoTherapeutics Reports Inducement Grants

BioTech 365

Brooklyn ImmunoTherapeutics Reports Inducement Grants Brooklyn ImmunoTherapeutics Reports Inducement Grants BROOKLYN, N.Y.–(BUSINESS

52

MicroMesh: a microscopic polymeric network to attack glioblastoma multiforme

Scienmag

Researchers at Istituto Italiano di Tecnologia in collaboration with Stanford Medicine and the San Raffaele Hospital have demonstrated with preclinical studies the effectiveness of a new biomedical implant for the treatment of glioblastoma multiforme Credit: D.

AdaptHealth Corp. Schedules First Quarter 2021 Financial Results and Conference Call

BioTech 365

AdaptHealth Corp. Schedules First Quarter 2021 Financial Results and Conference Call AdaptHealth Corp. Schedules First Quarter 2021 Financial Results and Conference Call PLYMOUTH MEETING, Pa.–(BUSINESS –(BUSINESS WIRE)–AdaptHealth Corp.

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Stone Age black bears didn’t just defecate in the woods – they did it in a cave too

Scienmag

Scientists have sequenced ancient DNA from soil for the first time and the advance will transform what is known about everything from evolution to climate change. Credit: Devlin A.

DNA 59