Fri.Dec 10, 2021

article thumbnail

Latest Roche results show promise for new type of cancer immunotherapy

Bio Pharma Dive

Updated Phase 2 data suggested an experimental drug targeting the protein TIGIT could bolster the benefit of Roche's Tecentriq in certain people with advanced lung cancer.

Protein 317
article thumbnail

Biogen: This train wreck was due

World of DTC Marketing

MY POINT : Success is always temporary. When all is said and one, the only thing you’ll have left is your character. Right now, I could make a great argument that Biogen’s character is trashed and that they are a company in dire need of authentic leadership. Massive layoffs could be headed to Biogen due to the disappointing rollout of its Alzheimer’s drug Aduhelm that generated only a few million dollars in revenue over the past two quarters.

Drugs 231
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Lilly deepens research ties in China with biotech deal

Bio Pharma Dive

The collaboration with Regor Therapeutics is another example of large pharma companies' interest in partnering with emerging biotechs from China.

article thumbnail

The Impossible Cheeseburger Claimed the Top Spot on Grubhub’s “Year in Food” Report

XTalks

Each year, food delivery platform Grubhub releases its “Year in Food” report, which analyzes millions of deliveries and highlights top orders. This year, the Impossible Cheeseburger made with plant-based ingredients beat out the spicy chicken sandwich for the top order position, increasing in popularity by 442 percent in 2021. Here are some more notable statistics from Grubhub’s “Year in Food” report.

Protein 105
article thumbnail

Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

article thumbnail

Moderna reveals first study results for seasonal flu vaccine

Bio Pharma Dive

Data from a small Phase 1 trial showed the biotech's vaccine spurred immune responses to four common strains, although they didn't appear significantly greater than an already available shot from Sanofi.

article thumbnail

Biohaven Eyes FDA Approval for Second Migraine Drug Zavegepant After Promising Trial Results

XTalks

Biohaven Pharmaceuticals revealed positive top line results from a late-stage trial which show that its migraine medication Zavegepant provides “ultra-rapid” pain relief in just 15 minutes. Zavegepant is similar to Biohaven’s approved migraine pill Nurtec (rimegepant); however, while Nurtec comes as an orally dissolved tablet (ODT), zavegepant is formulated as an intranasal spray.

More Trending

article thumbnail

Innovative silicon nanochip can reprogram biological tissue in living body

Scienmag

A silicon device that can change skin tissue into blood vessels and nerve cells has advanced from prototype to standardized fabrication, meaning it can now be made in a consistent, reproducible way. As reported in Nature Protocols, this work, developed by researchers at the Indiana University School of Medicine, takes the device one step closer to potential […].

article thumbnail

Intercept’s travails continue as it pulls NASH drug filing in EU

pharmaphorum

Already scrambling to refile its obeticholic acid (OCA) drug for non-alcoholic steatohepatitis (NASH) after the FDA rejected it last year, Intercept Pharma was hoping for more luck in Europe, but has now withdrawn its EU marketing application. Intercept had been hoping to extend the review period in the EU to allow time for results from an ongoing to phase 3 trial to come in, now due in the first quarter of next year, but conceded defeat yesterday.

Drugs 98
article thumbnail

How much do you know about digital pathology?

XTalks

Pathology is the study of the causes and effects of disease or injury, and pathologists are known as “the doctor’s doctor.” There is a paradigm shift happening in this field of medical science as pathology data is becoming increasingly digitized. Take this quiz to test your knowledge of digital pathology! Want to learn more? Register for this free webinar to learn more about a collaborative image management platform that was designed for digital pathology teams.

Doctors 95
article thumbnail

MicroRNAs: Biological indicators of the physiological status of animals

Scienmag

Known to be fine regulators of gene expression, microRNAs are small molecules that remain particularly stable in biofluids—blood, urine, etc. In humans, these molecules have revealed great potential as prognostic or diagnostic tools for many diseases such as various cancers, strokes, and, particularly, heart attacks. However, few studies have been carried out on their potential […].

article thumbnail

The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

article thumbnail

NHS waiting times reach record high of nearly six million

Pharma Times

In October 2021, over 356,000 people in England had been waiting for over six weeks for a key diagnostic test

113
113
article thumbnail

Atom laser creates reflective patterns similar to light

Scienmag

Cooled to almost absolute zero, atoms not only move in waves like light but also can be focused into shapes called caustics, similar to the reflecting or refracting patterns light makes on the bottom of a swimming pool or through a curved wine glass. Credit: Washington State University Cooled to almost absolute zero, atoms not […].

89
article thumbnail

Health minister welcomes new treatments for COVID-19 patients

Pharma Times

The treatments are being offered as an addition to vaccinations to maximise protection against COVID-19

article thumbnail

UTSW pharmacologists identify potential cure for tropical parasitic disease found in soil

Scienmag

Combining two agents to block a parasitic worm’s life cycle boosted survival from a potentially deadly tropical disease to 85% in animal models, far better than either treatment alone, according to a proof-of-concept study led by UT Southwestern Medical Center pharmacologists. Credit: Ariel Juno from the laboratory of James Lok, University of Pennsylvania Combining two agents to block […].

article thumbnail

Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

article thumbnail

Digital health firm ChronWell raises $6m for liver disease toolkit

pharmaphorum

US remote healthcare specialist ChronWell has raised $6 million from investors that will be used to accelerate the rollout of its patient management programmes for people with liver and gastrointestinal diseases. The financing involved new and existing backers, which have not been identified, and will be directed mainly to LIVErHEALTHY, a digital health programme that was launched by ChronWell last year.

article thumbnail

Disrupting flow of wood from rivers to oceans impacts marine environments

Scienmag

Ellen Wohl has always been fascinated by what happens in the deep sea. She studies interactions between rivers and water, the flow of sediment and wood, and the landforms created as a result. Credit: Emily Iskin/Colorado State University Ellen Wohl has always been fascinated by what happens in the deep sea. She studies interactions between […].

88
article thumbnail

Roche builds case for TIGIT combo in untreated lung cancer

pharmaphorum

Roche’s closely-watched combination of anti-TIGIT antibody tiragolumab and PD-L1 inhibitor Tecentriq has shown long-term efficacy in an ongoing trial in lung cancer, adding to the evidence that two immunotherapies may be better than one. Like PD-L1, TIGIT is thought to act as a molecular brake that stops T cells from attacking tumours, and tiragolumab is currently leading the pack among drugs targeting the immune checkpoint.

article thumbnail

Oregon State researchers develop advanced catalysts for clean hydrogen production

Scienmag

CORVALLIS, Ore. – Oregon State University research into the design of catalysts has shown that hydrogen can be cleanly produced with much greater efficiency and at a lower cost than is possible with current commercially available catalysts. Credit: OSU CORVALLIS, Ore. – Oregon State University research into the design of catalysts has shown that hydrogen […].

article thumbnail

The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

article thumbnail

Frontiers Health Digital Innovators: Orion Pharma’s Sammeli Likkanen

pharmaphorum

pharmaphorum’s founder, Dr Paul Tunnah, continues his Frontiers Health Digital Innovators series by speaking with Orion Pharma’s director of digital medicine Sammeli Likkanen. Live from Frontiers Health conference in Milan, Sammeli provides insights into the difference between digital health and digital transformation. He discusses how virtual reality (VR) is changing digital therapeutics, and what Orion’s role is in utilising VR technology.

article thumbnail

First real-world study shows the potential of gait authentication to enhance smartphone security

Scienmag

Real-world tests have shown that gait authentication could be a viable means of protecting smartphones and other mobiles devices from cyber crime, according to new research. A study led by the University of Plymouth asked smartphone users to go about their daily activities while motion sensors within their mobile devices captured data about their stride […].

article thumbnail

Rita Ribeiro

Pharma Marketing Network

Rita Ribeiro, Product Director, Oncology Marketing, is a marketing leader with 20 years of global and US healthcare experience in pharmaceutical, medical device and services organizations. She has developed and implemented regionalized, integrated strategic plans to increase brand awareness and drive organizational growth across multiple therapeutic areas and service networks.

article thumbnail

UTEP to work on solutions to reduce drug use-related HIV in the el Paso-ciudad Juárez border

Scienmag

EL PASO, Texas (Dec. 10, 2021) – The University of Texas at El Paso will develop a sustainable public health intervention to suppress human immunodeficiency virus (HIV) in people who use drugs in the El Paso-Ciudad Juárez border region to help slow the spread of HIV. The initiative will be funded by a $3 million […].

Drugs 84
article thumbnail

Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

article thumbnail

Angela Ornce, Intouch Boomerang

Intouch Solutions

The Great Resignation — have you heard that term yet? The Bureau of Labor Statistics reported this week that 4.2 million people had quit their jobs in October. Most of 2021 has been like this — lots and lots of people leaving their jobs. Some of this is related to pandemic fears, but that’s not the only thing driving “the big quit,” and employers across sectors are scrambling to figure out what’s missing and to keep their employees.

52
article thumbnail

Mutations in TP53 gene linked to aggressive prostate cancer

Scienmag

Men who have mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found. The findings were reported in the journal European Urology. Researchers from more than a dozen institutions across the United States collaborated on the study. Dr. Kara N. Maxwell, assistant professor of […].

Gene 83
article thumbnail

CytoDyn to Hold Webcast and Live Q/A on December 14

BioTech 365

CytoDyn to Hold Webcast and Live Q/A on December 14 CytoDyn to Hold Webcast and Live Q/A on December 14 VANCOUVER, Washington, Dec. 10, 2021 (GLOBE NEWSWIRE) — CytoDyn Inc.

40
article thumbnail

Doctoral student finds alternative cell option for organs-on-chips

Scienmag

Organ-on-a-chip technology has provided a push to discover new drugs for a variety of rare and ignored diseases for which current models either don’t exist or lack precision. In particular, these platforms can include the cells of a patient, thus resulting in patient-specific discovery. Credit: Texas A&M Engineering Organ-on-a-chip technology has provided a push to […].

Doctors 82
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Participate in the new COVID-19 health survey

Sciensano

Sciensano launches the 9 th COVID -19 health survey with the focus on how we experience the 4 th COVID -19 wave. We reached over 60,000 people with our previous surveys, can we also count on you this time? Fill out the survey. The 9th COVID -19 health survey awaits you. Are you 18 years or older and living in Belgium? Then complete our online survey before the 24th of December 2021.

article thumbnail

Nasal vaccine may aid fight against new viral variants

Scienmag

The emergence of COVID-19 variants such as delta and omicron have sent scientists scrambling to determine whether existing vaccinations and boosters are still effective against new strains of SARS-Cov-2. A new response to the rapidly mutating virus might be found right at the door to our lungs, says Yale’s Akiko Iwasaki, the Waldemar Von Zedtwitz […].

article thumbnail

The Governance Institute Releases 2021 National Survey of Healthcare Governance

BioTech 365

The Governance Institute Releases 2021 National Survey of Healthcare Governance The Governance Institute Releases 2021 National Survey of Healthcare Governance Boards have made small advances in diversity; less time is spent on strategic planning LINCOLN, Neb., Dec.

40
article thumbnail

Differentiating friends from foes in the fungal root microbiome

Scienmag

Credit: Stéphane Hacquard/MPIPZ Complex microbial communities inhabit plants and modulate their development. Roots especially, host a wide diversity of micro-organisms – including bacteria and fungi – that directly influence plant health. Researchers from the MPIPZ previously discovered that these fungi are important members of the root microbiome that can promote plant growth, but only when […].

article thumbnail

The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.