Fri.Jan 14, 2022

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Pharma’s outdated hiring practices

World of DTC Marketing

One of the reasons it’s a job-seekers market because candidates today want more from their employers. They want a good work-life balance and want to be valued as a contributor to the success of their company. We live in an instant gratification world. Anything and everything we could ever want is at our fingertips, from the food we eat to the movies we watch.

HR 277
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Medicare faces blowback over plan to limit coverage of Biogen's Alzheimer's drug

Bio Pharma Dive

Biogen, along with allies in industry, plans to pressure Medicare to water down its policy, which limits coverage of Aduhelm and drugs like it to clinical trials.

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2022 will see pharma target nutraceutical products to tap into consumer spending on preventative health: CPhI Worldwide Report

Pharma Mirror

Amsterdam, CPhI Worldwide – the world’s largest pharma event, which will be hosted at the Frankfurt Messe (1-3 November, 2022) – releases the final part of its annual report with far reaching predictions for 2022 and beyond into 2025 for the nutraceuticals market. The findings explore the long-term trends underway in the global nutraceutical industry, with consumers predicted to increase spending on natural products and sustainable formulations that can offer ‘preventative or proactive’ health b

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Otsuka backs GrayMatters’ digital wearable tech for mental disorders

pharmaphorum

Japanese pharma group Otsuka has led a $10 million first-round financing of GrayMatters Health, an Israeli company developing a digital health approach to the management of mental illness. Otsuka Medical Devices is also taking some rights to GrayMatters’ platform – called Prism – in Japan and some other Asian countries in connection with the financing, which was supported by Joy Ventures, J-Ventures, J-Impact, and existing backers Marius Nacht and Joyance Ventures.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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New study sheds light on origins of life on Earth

Scienmag

New Brunswick, N.J. (Jan. 14, 2022) – Addressing one of the most profoundly unanswered questions in biology, a Rutgers-led team has discovered the structures of proteins that may be responsible for the origins of life in the primordial soup of ancient Earth. Credit: Rutgers New Brunswick, N.J. (Jan. 14, 2022) – Addressing one of the […].

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EMA sets out proposals to reform EU’s clinical trials framework

pharmaphorum

The European Commission, EMA and national regulators within the EU have launched an initiative to change the way clinical trials are designed and run in order to position the bloc as an international “focal point” for clinical research. The broad strokes of the proposals are laid out in a document entitled Accelerating Clinical Trials in the EU (ACT EU) that lists priority actions that will be taken, including measures to allow greater use of innovative clinical trial designs.

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The evolution of clinical trials: the pharmaphorum podcast

pharmaphorum

In the latest episode of the pharmaphorum podcast, Dr Paul Tunnah speaks to head of Patient Engagement at Syneos Health, Marie Emms, and Elligo executive vice president and general manager of Worldwide Clinical Trials Early Phase Services, Keith Fern. Together they discuss the changing nature of clinical trials how COVID-19 impacted the sector, and the role technology is playing in supporting trial enrolment and retention.

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Origin of rare disease FOP rooted in muscle regeneration dysfunction

Scienmag

Fibrodysplasia ossificans progressiva (FOP) is a rare disease characterized by extensive bone growth outside of the normal skeleton that pre-empts the body’s normal responses to even minor injuries. It results in what some term a “second skeleton,” which locks up joint movement and could make it hard to breathe. However, new research in mice by […].

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WHO grants seal of approval to two new COVID-19 treatments

Outsourcing Pharma

The World Health Organization has recommended the drugs for COVID-19 patients, broadening the range of therapies to combat the virus behind the pandemic.

Drugs 98
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Tackling plastics pollution

Scienmag

Despite the society-changing improvements that plastic materials have brought to humanity, there’s no question that they also present us with new challenges regarding what to do with the large amounts of plastic waste we generate, from the oil-based chemicals used to create products to the microplastics found everywhere after plastics breakdown in the environment.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Gates Foundation supports HIV and malaria research

Pharma Times

Vir Biotech has launched a new antibody research initiative, expanding its partnership with the Bill & Melinda Gates Foundation

Research 101
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A catalyst for more efficient green hydrogen production

Scienmag

The climate crisis requires ramping up usage of renewable energy sources like solar and wind, but with intermittent availability, scalable energy storage is a challenge. Credit: Georgia Tech The climate crisis requires ramping up usage of renewable energy sources like solar and wind, but with intermittent availability, scalable energy storage is a challenge. […].

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The 340B Rebate Model: A Solution to the Contract Pharmacy Controversy

Drug Channels

Today’s guest post comes from Jeremy Docken, Founder and Chief Strategy Officer at Kalderos. Jeremy describes Kalderos’ 340B rebate model. He discusses an independent research organization’s study of the 340B rebate model’s impact on covered entities’ cash flow. To learn more, download the whitepaper: The Kalderos 340B Rebate Model In Action: Ensuring a Thriving and Sustainable 340B Program.

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Electricity regulation with equity and justice for all

Scienmag

By Kiran Julin Credit: Cristen Farley/Berkeley Lab By Kiran Julin Poring over the line items on your monthly electricity bill may not sound like an enticing way to spend an afternoon, but the way electricity bills are structured has a significant impact on equitable energy access and distribution. For example, fixed fees can have a […].

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Howard Solomon, 94, Dies; His Business Success Had a Personal Connection

NY Times

After one of his sons fell into a deep depression, he helped him recover. He later licensed an antidepressant that was a boon to his pharmaceutical company.

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Low-temperature DeNOx catalyst for reducing ultrafine particle emission

Scienmag

Recently, there has been growing demand for DeNOx catalysts that can treat nitrogen oxides (NOx) at low temperatures, to increase energy efficiency when processing flue gas in industrial combustion facilities. NOx are emitted during the combustion of fossil fuels and are the leading cause of ultrafine particles (UFPs) formed via chemical reactions in the atmosphere. […].

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While Omicron continues to dominate across the world, COVID-19 travel requirements remain

Pharma Times

Djokovic drama causes a racket: so how would the UK respond?

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Study finds national and international frameworks are imperative for implementing nature-based solutions in Asia

Scienmag

Recognized by the United Nations Framework Convention on Climate Change (UNFCCC) and the Convention on Biological Diversity (CBD), nature-based solutions (NbS) refer to solutions that bring together human well-being, environmental sustainability, and biodiversity benefits. NbS are also key elements to post-COVID-19 pandemic recovery strategies. NbS include a variety of elements, starting from ecosystem-based climate change […].

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Financial Planning for People With Chronic Diseases

NY Times

Financial planning for people with chronic diseases is complicated and multifaceted. Start by building a team of people to help.

Drugs 67
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Genetic strategy reverses insecticide resistance

Scienmag

Insecticides play a central role in efforts to counter global impacts of mosquito-spread malaria and other diseases, which cause an estimated 750,000 deaths each year. These insect-specific chemicals, which cost more than $100 million to develop and bring to market, also are critical to controlling insect-driven crop damage that poses a challenge to food security. […].

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New patent for Adamas Pharma drug GOCOVRI

Drug Patent Watch

Annual Drug Patent Expirations for GOCOVRI Gocovri is a drug marketed by Adamas Pharma and is included in one NDA. It is available from one supplier. There are seventeen patents…. The post New patent for Adamas Pharma drug GOCOVRI appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
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UTA working with DFW aerospace companies to enable autonomous flight systems

Scienmag

A University of Texas at Arlington aerospace engineer is teaming with industry partners to develop control systems for autonomous aerial vehicles that will increase their safety and detect structural issues. Credit: UT Arlington A University of Texas at Arlington aerospace engineer is teaming with industry partners to develop control systems for autonomous aerial vehicles that […].

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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New patent for La Jolla drug GIAPREZA

Drug Patent Watch

Annual Drug Patent Expirations for GIAPREZA Giapreza is a drug marketed by La Jolla Pharma and is included in one NDA. It is available from one supplier. There are nine…. The post New patent for La Jolla drug GIAPREZA appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
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Researchers identify a set of cellular receptors in humans and other species for the eastern equine encephalitis virus, other members of the alphavirus family

Scienmag

A new study led by researchers at Harvard Medical School has identified a set of cellular receptors for at least three related alphaviruses shared across mosquitoes, humans, and animals that host the virus. Going a step further, the researchers tested a “decoy” molecule that successfully prevented infection and slowed disease progression in a series […].

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Pharma R&D investment report shows positive signs: Deloitte

Outsourcing Pharma

According to the companyâs 12th Annual Pharmaceutical Innovation Report, pharmaceutical R&D return on investment has climbed to its highest peak since 2014.

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$2 million NIH MIRA grant will support trailblazing research in UMass Amherst lab

Scienmag

Jianhan Chen, a University of Massachusetts Amherst chemistry and biochemistry and molecular biology professor, has received a five-year, $2 million National Institutes of Health (NIH) grant to support research in his computational biophysics lab aimed at better understanding the role of intrinsically disordered proteins (IDPs) in biology and human disease.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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China SXT Pharmaceuticals, Inc. Announces Proposed Underwritten Public Offering of Ordinary Shares and Pre-Funded Warrants to Purchase Ordinary Shares

BioTech 365

China SXT Pharmaceuticals, Inc. Announces Proposed Underwritten Public Offering of Ordinary Shares and Pre-Funded Warrants to Purchase Ordinary Shares China SXT Pharmaceuticals, Inc.

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Baszucki Brain Research fund and Milken Institute announce grant recipients for bipolar disorder therapeutic research

Scienmag

Washington, D.C. – January 14, 2022 – The Baszucki Brain Research Fund and the Milken Institute’s Center for Strategic Philanthropy are pleased to announce that 45 scientists worldwide will receive funding to advance research for bipolar disorder. Today, the Baszucki family announced $9 million in grants to support bipolar disorder focused research.

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iCRYO Keeps the Momentum from 2021 Moving into 2022

BioTech 365

iCRYO Keeps the Momentum from 2021 Moving into 2022 iCRYO Keeps the Momentum from 2021 Moving into 2022 Houston, Texas, United States, Jan. 14, 2022 (GLOBE NEWSWIRE) — 2021 was iCRYO’s strongest year as a company.

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Study reveals link between brain cell development and risk of schizophrenia

Scienmag

Scientists from Cardiff University have discovered new links between the breakdown in brain cell development and the risk of schizophrenia and other psychiatric disorders. Genetic risk factors are known to disrupt brain development in a number of these disorders, but little is known about which aspects of this process are affected. This research is the […].

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.