Sun.Jun 19, 2022

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CVS Health Banks on Trust to Increase Diversity in Clinical Trials

BioSpace

CVS Health has seen about 40% patient diversity in the work it has done so far, Josh Rose, VP and head of decentralized clinical trials, site solutions and strategy told BioSpace.

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A small lowering of the groundwater level can destroy house foundations

Scienmag

As early as 2000 years ago, the great Roman architect Vitruvius wrote that wooden piles must be driven down into mud or waterlogged ground and buried completely in order to create a stable foundation for buildings. A new thesis from the University of Gothenburg shows that wooden pile foundations show visible damage after only a […].

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Pfizer Buys Stake in Valneva to Advance Lyme Disease Vaccine

BioSpace

Pfizer inked an Equity Subscription Agreement with France-based Valneva. They also updated their Collaboration and License deal for a Lyme disease vaccine that was announced in April.

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Gene discovery indicates motor neurone diseases caused by abnormal lipid processing in cells

Scienmag

A new genetic discovery adds weight to a theory that motor neurone degenerative diseases are caused by abnormal lipid (fat) processing pathways inside brain cells. This theory will help pave the way to new diagnostic approaches and treatments for this group of conditions. The discovery will provide answers for certain families who have previously had […].

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Janssen Recruiting for Phase III Trials of Potential Myasthenia Gravis Game Changer

BioSpace

BioSpace spoke with Janssen's Fiona Elwood about the company's myasthenia gravis candidate nipocalimab, which is currently recruiting for two Phase III trials.

Trials 103
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National poll: Some parents skip steps to minimize firework risks to kids

Scienmag

ANN ARBOR, Mich. – As communities prepare for Fourth of July festivities, some parents may be overlooking burn and injury risks for children, a new national poll suggests. Credit: University of Michigan Health C.S. Mott Children’s Hospital National Poll on Children’s Health ANN ARBOR, Mich. – As communities prepare for Fourth of July festivities, some […].

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Assessing the environmental impact of nuclear power generation

Scienmag

In a constantly evolving world, rapidly growing populations coupled with urbanization and industrialization are leading to an ever-increasing demand for energy. The challenge today lies in meeting these energy requirements while keeping global warming in check—a condition which fossil fuels do not fulfil. In an effort to mitigate the environmental degradation and natural resource depletion […].

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Clinical Catch-Up: AbbVie and Genmab, Intra-Cellular, Sanofi and GSK

BioSpace

Genmab and AbbVie announce positive data in large b-cell lymphoma, Intra-Cellular's bipolar depression candidate hits the endpoint in Phase III and more.

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Chinese Medical Journal review explores the role of macrophages in the progression of acute kidney injury to chronic kidney disease

Scienmag

Acute kidney injury (AKI) is a condition in which kidneys are unable to filter waste from the blood effectively, leading to various health complications. Numerous studies have demonstrated that acute kidney injury (AKI) subsequently leads to long-term renal damage and progresses into chronic kidney disease (CKD)—a more severe form of kidney failure.

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France Aims to Become European Leader in Life Sciences Innovation

BioSpace

The government of France launched its Healthcare Innovation 2030 strategy that aims to turn the country into a European innovation leader within the next eight years.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Scientists conceptualize a species ‘stock market’ to put a price tag on actions posing risks to biodiversity

Scienmag

So far, science has described more than 2 million species, and millions more await discovery. While species have value in themselves, many also deliver important ecosystem services to humanity, such as insects that pollinate our crops. Credit: Dr Kessy Abarenkov So far, science has described more than 2 million species, and millions more await discovery. […].

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Scholar Rock Sees Modest Improvements in Phase II SMA Study

BioSpace

Extension data from the Phase II TOPAZ trial showed that apitegromab yielded sustained and continued benefits in non-ambulatory patients with types 2 and 3 spinal muscular atrophy (SMA).

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Bodychecking experience does not lower risk of injury for teen hockey players

Scienmag

Youth hockey players with more years of bodychecking experience were at significantly higher risk of concussion than their peers with less bodychecking experience, according to new research in CMAJ (Canadian Medical Association Journal) [link] “We found that among ice hockey players aged 15–17 years in elite leagues that allow bodychecking, the rates of injury and concussion were more […].

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FDA Action Alert: BMS, TG, Spero and Merck

BioSpace

BMS, TG Therapeutics, Spero and Merck are all preparing for PDUFA dates over the next couple of weeks. Here's a closer look.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Novel drug combo activates natural killer cell immunity to destroy cancer cells

The Pharma Data

Most skin cancer drugs that activate the immune system work by triggering immune cells, called T cells, to attack tumors, but when T cells are activated for too long, they can wear out and cease to function. A new study led by Penn State College of Medicine scientists finds that another type of immune cell – natural killer cells – can be harnessed to pick up the slack when T cells no longer work and may also reinvigorate T cells to attack melanoma tumors.

Drugs 52
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New Research Could Lead to Improved Therapies for Traumatic Brain Injury

BioSpace

New research conducted by scientists at UC Irvine shines new light on understanding traumatic brain injuries.

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Canadian comms giant Telus buys digital health player LifeWorks

pharmaphorum

Canadian wireless network carrier Telus has agreed a C$2.9 billion ($2.2 billion) deal to acquire LifeWorks, a digital health specialist that will bulk up the telecoms company’s Telus Health unit. Toronto-based LifeWorks provides cloud-based telehealth as well as in-person health services – with an emphasis on mental health and wellbeing – that employers can make available to their workforces in order to identify issues quickly and help people recover as quickly as possible.

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Researcher, CEO, Mentor – The Role of a Principal Investigator, Explained

BioSpace

Are you passionate about research, business, science and leadership? If so, you might be interested in a job as a principal investigator.

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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Ship2B Ventures

BioTech 365

Venture Capital firm that invests in the best impact startups. As impact investors they seek to generate triple profitability: economic, social and environmental.

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AbbVie's Skyrizi Becomes First FDA-Approved IL-23 Inhibitor for Crohn's Disease

BioSpace

???????The FDA's decision is based on positive results from two induction and one maintenance clinical study of AbbVie's Skyrizi for Crohn's disease.

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Artificial Intelligence In Radiology Market Size & Market Analysis

BioTech 365

Artificial Intelligence in Radiology Market is valued at USD 53.9 Million in 2021 and expected to reach USD 461.1 Million by 2028 with a CAGR of 35.9% over the forecast period.

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Which pharmaceutical drugs have the most drug patents in Peru?

Drug Patent Watch

This chart shows the drugs with the most patents in Peru. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.…. The post Which pharmaceutical drugs have the most drug patents in Peru? appeared first on DrugPatentWatch - Make Better Decisions.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Biophytis – therapeutics to slow down the degenerative processes associated with aging

BioTech 365

Biophytis is a clinical-stage biotechnology company specialized in the development of therapeutics that are aimed at slowing the degenerative processes associated with aging and improving functional outcomes for patients suffering from age-related diseases, including severe respiratoy failure in patients suffering … Continue reading →

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Pancreatic Cancer Diagnostics Market Size & Market Analysis

BioTech 365

Registering a CAGR of 8.8% over the forecast period of 2022-2027, the global Pancreatic Cancer Diagnostic market is anticipated to reach the market value of US$ 6224 million in the year 2027 from US$ 3865 million in the year 2021.

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Asthma Drugs Market Size & Market Analysis

BioTech 365

The asthma drugs market is projected to reach US$ 34,136.10 million in 2028 from US$ 24,239.17 million in 2021; it is estimated to grow at a CAGR of 5.0 % during 2021-2028.

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Artificial Intelligence in Medical Imaging Market Size & Market Analysis

BioTech 365

The global AI in medical imaging market is projected to cross USD 10 billion by 2027, growing at a CAGR of 45% from USD 1.06 billion in 2021.

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.