Wed.Nov 25, 2020

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My thoughts this Thanksgiving

World of DTC Marketing

SUMMARY: This Thanksgiving, my thoughts turn to families who are going to have an empty seat at the table because of COVID-19. Over 2100 people died from COVID-19 yesterday as the void in leadership continues. Maybe I’m too empathetic, but these people are someone’s dad, father, son, or daughter, and many of these deaths could have been prevented if only we had leadership who put as much emphasis on prevention as they did on “fake news.” On Facebook, local newspaper feeds

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Thankful for Biopharma Breakthroughs

BioSpace

Despite the constant need for social distancing, mask-wearing, and the isolation and economic uncertainty that resulted from the outbreak, there is still much to be thankful for when families gather around a virtual table to break bread and carve the turkey this year.

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GE Healthcare’s AI tool helps clinicians intubate patients accurately and safely

pharmaphorum

An artificial intelligence tool developed by GE Healthcare twinned with a mobile X-ray device can help the placement of endotracheal tubes (ETTs), a necessary step for COVID-19 patients who require ventilation. The new tool – part of GE’s Critical Care Suite 2.0 – helps bedside staff and radiologists assess patients before intubation and make sure ETTs are positioned correctly which should reduce complications.

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Final Ruling on Medicare Most-Favored-Nation Drug Pricing Set for Federal Register Publication

BioSpace

The interim final rule aligns payment for Medicare Part B therapeutics with international prices and removes incentives for physicians to prescribe more expensive drugs and biologics.

Drugs 103
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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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‘Mistake’ led to AZ’s more effective lower-dose COVID-19 shot

pharmaphorum

AstraZeneca’s research chief has said that the more effective dosing regimen of its coronavirus vaccine was discovered by accident. According to Reuters , the AstraZeneca development team made a minor mistake that made them realise they could significantly boost the success rate of the vaccine, codenamed AZD1222. Results announced earlier this week showed that by giving a half dose, followed by a full dose a month later, the vaccine’s efficacy could be boosted from 62% to around 90%.

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New EU pharma strategy looks to future-proof healthcare sector, stimulate innovation and boost access to biosimilars and generics

BioPharma Reporter

The new EU Pharmaceutical Strategy, adopted today by the European Commission, is designed to improve and accelerate patientsâ access to safe and affordable medicines and address unmet medical needs in the areas of antimicrobial resistance, cancer, and rare diseases.

More Trending

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Doctors use existing treatment earlier to save the lives of Covid-19 patients

Scienmag

Credit: Lancaster University The lives of patients hospitalised with COVID-19 are being saved by doctors who are using an existing medical treatment at an earlier stage. Dr Luigi Sedda of Lancaster University analysed the results from the team at Wrightington, Wigan and Leigh Teaching Hospitals NHS Trust (WWL). Their research has now been published in […].

Doctors 98
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COVID-19 lessons for how pharma should support patient advocacy

pharmaphorum

Trio Health’s Neil McGregor-Paterson asks whether the healthcare industry has paid enough attention to the patient voice during COVID-19 and looks at the many ways pharma can improve the patient experience across the sector going forward. Never has the health and care voluntary sector (HCVS) played such a critical role in supporting our nation´s health and wellbeing.

Medicine 115
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New patent for Antares Pharma drug XYOSTED (AUTOINJECTOR)

Drug Patent Watch

Annual Drug Patent Expirations for XYOSTED+%28AUTOINJECTOR%29 Xyosted (autoinjector) is a drug marketed by Antares Pharma Inc and is included in one NDA. It is available from one supplier. There are…. The post New patent for Antares Pharma drug XYOSTED (AUTOINJECTOR) appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 98
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Digitally engaging doctors around the world

pharmaphorum

Pharmaceutical marketing budgets are going through a period of readjustment as companies explore and exploit a myriad of different digital channels to deliver content to, and engage with, their doctors and other audiences. The average allocation to digital channels with marketing budgets has doubled since 2016, up to 34% for 2020 according to Indegene research, and over a third of companies expect digital budget allocations to increase by more than 50% over the next three years.

Doctors 105
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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Engineering researcher receives EPSCoR grant for electrocatalysis work

Scienmag

Research will provide scientific basis improving battery materials and electrocatalysts for polymer recycling and water treatment Credit: Russell Cothren, University of Arkansas Lauren Greenlee, associate professor of chemical engineering at the University of Arkansas, received a $750,000 award from the Department of Energy to investigate the chemical and electronic structure of iron and oxygen atoms. […].

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Why Being a Generalist in Clinical Research is Your Best Career Move!

Clinical Trial Gurus

Regardless of the industry, employers will seek employees who will help solve the problems that their business is facing. Generalists have the advantage of marketing themselves as having varying skills that can be used to solve different problems. Job seekers are therefore encouraged to demonstrate on their CVs that they are problem solving generalists.

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Immune strategy based on limited information in the network

Scienmag

Credit: ©Science China Press The novel coronavirus outbreak is a global pandemic that has spread to more than 200 countries and territories around the world. Currently, countries and territories are fighting the spread of the disease using social distancing such as quarantine, testing or isolation which can be regarded as immunization. Given the important role […].

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COVID-19 pandemic has emphasised existing health inequalities, research finds

Pharma Times

New report conducted by Imperial College London researchers and Philips UK highlights issues within the NHS

Research 105
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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Evidence of the interconnectedness of global climate

Scienmag

Analysis finds melting ice sheet affects a second thousands of miles away Credit: Thomas Ronge To see how deeply interconnected the planet truly is look no further than the massive ice sheets on the Northern Hemisphere and South Pole. Thousands of kilometers apart, they are hardly next-door neighbors, but according to new research from a […].

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A pivotal moment for digital health adoption

pharmaphorum

Former chief digital officer for the NHS, Juliet Bauer, is now applying her experience to the private sector through video consultation firm Livi. She shares her thoughts on how well the NHS is integrating digital health and what the public and private sectors can do to further boost adoption. Bauer’s path to working in the NHS began when she spent many months in the care of the health service with a highly risky pregnancy and an extremely premature baby in NICU.

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Neutrinos yield first experimental evidence of catalyzed fusion dominant in many stars

Scienmag

The CNO energy-production mechanism in the universe is detected Credit: Borexino Collaboration AMHERST, Mass. – An international team of about 100 scientists of the Borexino Collaboration, including particle physicist Andrea Pocar at the University of Massachusetts Amherst, report in Nature this week detection of neutrinos from the sun, directly revealing for the first time that […].

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BMS inks drug discovery deal with Schrödinger

Pharma Times

Deal will focus on developing small molecules against a number of diseases

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Digital atlas makes Micronesia more easily researched than Hawaii, Fiji, and Guam

Scienmag

Credit: Island Research & Education Initiative With the culmination of a five-year effort to gather a breadth of geospatial data and display it on an interactive digital atlas, the four main islands of the Federated States of Micronesia are now more easily researched than any other island in the Pacific, including Hawaii, Guam, and Fiji. […].

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Escitalopram vs Citalopram – WHAT is the difference?

Druggist

Citalopram is a popular antidepressant prescribed in the UK. It is also one of the most prescribed medicines in the UK. Although escitalopram is ‘related’ to citalopram, it significantly less prescribed. Today I will review differences between escitalopram and citalopram. Escitalopram vs citalopram, a summary of the post: Escitalopram vs citalopram: legal status.

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Barley pan-genome: IPK scientists reach milestone on the way to ‘transparent’ barley

Scienmag

Credit: Photo: IPK Leibniz Institute/ Andreas Bähring In order to record all genetic information of an individual, its genome must be completely decoded. IPK scientists and international partners for barley already succeeded in doing this three years ago (Mascher et al. 2017). But to understand the genetic information of the entire barley species, much more […].

Genome 88
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GSK launches late-stage study of RSV vaccine in pregnant mothers

Pharma Times

Shot will be evaluated in pregnant mothers and their newborn infants

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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The smell of cooperation

Scienmag

Research team with the University of Göttingen finds effect of odour on helpfulness in rats Credit: Manon Schweinfurth Despite their reputation, rats are surprisingly sociable and actually regularly help each other out with tasks. Researchers at the Universities of Göttingen, Bern and St Andrews have now shown that a rat just has to smell the […].

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Millions of Americans Who Struggle with Drug Costs Are Also Hungry: Help Them This Thanksgiving

Pharmacy Checkers

In Thanksgiving seasons past, I have written posts connecting the problems of high drug prices and hunger in America. Where people and households are struggling to afford food, there’s a greater likelihood that they are forgoing needed medical treatments, including prescription drugs. The problem is far worse for people with chronic medical conditions.

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ETRI Hologram Technologies won I-zone Best Prototype Award in Displayweek 2020

Scienmag

1?m pixel pitch panel and 360° table top hologram were exhibited. warded for the first time to South Korea, a recognition of ETRI’s future display technology Credit: Electronics and Telecommunications Research Institute(ETRI) A hologram technology developed by South Korean researchers has won the top prize at one of the world’s most renowned conferences on display […].

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Over half of pharmacists report that COVID-19 has impacted their mental health

Pharma Times

Survey from The Royal Pharmacy Society shows impact of pandemic on pharmacists’ mental health

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Scientists develop new gene therapy for eye disease

Scienmag

Credit: Professor Jane Farrar and Dr Daniel Maloney, Trinity College Dublin Scientists from Trinity College Dublin have developed a new gene therapy approach that offers promise for one day treating an eye disease that leads to a progressive loss of vision and affects thousands of people across the globe. The study, which involved a collaboration […].

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Bioterrorism: A Threat To The Healthcare And Global Peace

Delveinsight

The spread of Covide-19 pandemic has brought significant attention from the government and healthcare bodies around the world towards the threat of biological agents (bacteria, viruses or toxins). Over the course of one year, Covid-19 has created serious health challenges and economic destruction around the world. Motivated by the havoc caused by Covid-19, terrorists in the future might deliberately-induced the disease outbreaks in the countries and regions opposing their ideology.

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Wheat diversity due to cross-hybridization with wild grasses

Scienmag

Credit: Rebecca Leber, UZH A variety of bread wheat that flourishes across Switzerland would remain just a poorly growing grass in India. This ability to adapt to regional climate conditions and environmental factors makes bread wheat the most commonly grown crop around the world. Its cultivation dates back around 8,000 years. Over time, more than […].

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Egle Therapeutics Identifies First Novel Regulatory T-cell Targets in Research Alliance with Takeda

The Pharma Data

Nov. 26, 2020 10:30 UTC. PARIS–( BUSINESS WIRE )– Egle Therapeutics SAS (Egle), an emerging biotechnology company focused on developing first-in class immunotherapies targeting immune suppressor regulatory T-cells (Tregs) for oncology and autoimmune diseases, today announces that it has achieved the first milestone in its strategic research alliance with Takeda Pharmaceutical Company Limited (“Takeda”).

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.