Wed.Feb 17, 2021

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Novartis expects sales lift from expanded heart drug approval

Bio Pharma Dive

The Swiss drugmaker's pill Entresto is now cleared in the U.S. for use in patients with stronger hearts, expanding the eligible population by two-thirds.

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How much to spend on DTC TV

World of DTC Marketing

SUMMARY: By far, the biggest question I get as a consultant is, “how much should we spend on DTC ads?” It’s important to understand that no formula can be applied across all health conditions and products. It varies by the size of your audience and the number of diagnosed and undiagnosed patients. DTC marketers will do a lot of research on brand messaging, but what’s really important is what action your target audience will take due to being exposed to your message.

Branding 180
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GSK returns to Vir with expanded deal to develop drugs for flu, other viruses

Bio Pharma Dive

The British drugmaker will pay the San Francisco-based biotech $225 million upfront, while also investing another $120 million in Vir shares.

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Haven: The strategy that didn’t fix healthcare

pharmaphorum

John Singer discusses the disbanding of Haven, the joint healthcare venture by Amazon, JP Morgan and Berkshire Hathaway, and the strategies that can help fix US healthcare. . “The market” was terrified when Warren Buffett, Jamie Dimon and Jeff Bezos got together to disrupt healthcare three years ago with the launch of Haven – in response to that news, healthcare stocks comprising a significant chunk of the $3.5 trillion health economy in the United States shed billions in value overnight.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Flow Acquires Halo Neuroscience to Develop Brain Stimulation Technology to Treat Depression

XTalks

Neurotech company Flow Neuroscience has acquired the rights to Halo Neuroscience’s brain stimulation technology in an effort to further its research goals of developing treatments for depression and other mental health disorders. The company will use and further build upon Halo’s research on neuromodulation technology to enhance its current medically certified transcranial direct current stimulation (tDCS) headset for depression.

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Roche and PatchAi partner on digital tool for cancer patients

pharmaphorum

Roche’s Italian subsidiary has joined forces with digital health startup PatchAi to roll out an app that aims to support people diagnosed with cancer. Roche and PatchAi have been working together on the Smart Health Companion (SHC), which was launched to oncology and haematology patients in July 2020, and will now step up their collaboration to offer it more widely.

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How Much Do You Know About Laboratory Asset Management?

XTalks

Laboratory asset management is integral to ensuring that operations get back to business once lockdowns are lifted. Take this quiz to test your knowledge of laboratory asset management and register for this webinar to learn more about the long-lasting benefits of this practice.

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COVID-19 increased demands on carers’ wellbeing, study finds

pharmaphorum

COVID-19 has increased demands on informal carers and severely increased demands on their mental, physical and financial wellbeing, according to a global study. Embracing Carers is a global initiative led by Germany’s Merck KGaA and is focused on recognising and raising awareness about the role of informal carers. It intends to develop solutions with global organisations and has produced the Carer Well-Being Index to provide insights and recommendations to help the public and private sector supp

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Research Finds Antibody That Can Clear Amyloid Plaques With Low Risk of Brain Bleeds

BioSpace

Researchers at Washington University School of Medicine in St. Louis, working with mice, discovered an antibody that removes amyloid plaques from brain tissue and blood vessels while not increasing the risk of brain bleeds.

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Building early relationships: a gamechanger for pioneering rare disease treatment

pharmaphorum

Advocacy groups play a crucial role in both driving access to innovative treatment and services and educating patients and caregivers on novel breakthroughs. On average, it takes more than four years to receive an accurate diagnosis of a rare disease. 1 This diagnostic odyssey has pushed patients and caregivers online to self-diagnose and learn more about their symptoms.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Study: Screen surgery patients for frailty

Scienmag

Credit: The University of Texas Health Science Center at San Antonio SAN ANTONIO — Patients should be assessed for frailty before having many types of surgery, even if the surgery is considered low risk, a review of two national patient databases shows. Frailty is a clinical syndrome marked by slow walking speed, weak grip, poor […].

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Life Science Careers: Leveraging AI in Talent Acquisition and Industry Expertise for Employers and Employees

XTalks

At the helm of industry-leading teams is the right combination of expertise, skills and experiences that help drive forward business and innovation. This begins with recruitment and acquisition of the right talent. While a lot of companies aim to recruit and acquire talent from external sources to diversify and attain specific skillsets, others may opt to leverage and tap potential from employees within their organization, recognizing their experience and aptitudes.

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Fish diet heats up marine biodiversity hotspot

Scienmag

Credit: Victor Huertas. Scientists have discovered a never-before-seen biodiversity pattern of coral reef fishes that suggests some fishes might be exceptionally vulnerable to environmental change. A new study shows plankton-eating coral reef fishes (planktivores) are far more diverse than others in the Indo-Australian Archipelago, a global marine biodiversity hotspot.

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Why Every Organization Needs a Clinical Data Strategy

XTalks

The different types and sources of data produced by clinical trials have been expanding in recent years, creating new challenges for consolidating, standardizing and analyzing the trial results. The tools for integrating data analysis methods have not kept pace with the advances in research technology, causing time delays and inefficiencies in the clinical trial process.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Damage to the heart found in more than half of COVID-19 patients discharged from hospital

Scienmag

Credit: European Heart Journal Around 50% of patients who have been hospitalised with severe COVID-19 and who show raised levels of a protein called troponin have damage to their hearts. The injury was detected by magnetic resonance imaging (MRI) scans at least a month after discharge, according to new findings published today (Thursday) in the […].

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Reinforcements On the Way As COVID-19 Vaccines Questionable Against Some Variants

BioSpace

Several mutations of the SARS-CoV-2 virus that causes COVID-19, which are being called variants, are increasingly being found around the world.

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Edible holograms could someday decorate foods

Scienmag

Credit: Adapted from ACS Nano 2021, DOI: 10.1021/acsnano.0c02438 Holograms are everywhere, from driver’s licenses to credit cards to product packaging. And now, edible holograms could someday enhance foods. Researchers reporting in ACS Nano have developed a laser-based method to print nanostructured holograms on dried corn syrup films. The edible holograms could also be used to […].

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A Guide to Setting – and Achieving – Career Goals

BioSpace

You can apply these career-planning and goal-setting techniques to establish career goals that are just as exciting as those you dreamed about as a kid.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Skoltech’s recent achievement takes us one step closer to Mars

Scienmag

Credit: Skoltech Scientists from the Skoltech Center for Computational and Data-Intensive Science and Engineering (CDISE) and the Skoltech Digital Agriculture Laboratory and their collaborators from the German Aerospace Center (DLR) have developed an artificial intelligence (AI) system that enables processing images from autonomous greenhouses, monitoring plant growth and automating the cultivation process.

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Is Ivabradine a Possible Treatment for a Heart-Related COVID-19 Symptom?

BioSpace

Currently, research is still ongoing with regards to the link between COVID and POTS. However, this increasing number of cases and the unfamiliarity of COVID's long-lasting effects leave a lot more for the researchers to unmask.

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University of Minnesota national study aims to improve US transportation system with accessibility data

Scienmag

Study adds education and health care destinations to annual measure of access to jobs by auto, transit, biking and walking. Credit: University of Minnesota Groundbreaking transportation research from the Accessibility Observatory at the University of Minnesota is entering its second phase with a new multiyear national pooled-fund study to measure access to destinations, such as […].

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Overuse of reliever medication for asthma a ‘major contributor’ to greenhouse gas emissions

Pharma Times

New data shows overuse of SABA relievers is responsible for 250,000 tonnes of CO2 emissions annually

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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Best PCD Pharma Franchise Company

Creogenic Pharma

Are You a. Retailer ? Distributor ? Doctor ? M.R. ? Wholesaler ? Get Started with. India's. No. 1*. Pharma. Franchise Company. Submit. Lowest Price. 250+ Products. Best Service. Best Quality. Best PCD Pharma Franchise Company: Regardless of the economic recession, the growth of the PCD Pharma Franchise sector in India has preserved that positive slope.

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Salk team reveals never-before-seen antibody binding, informing liver cancer, antibody design

Scienmag

Multi-institute collaboration uses X-ray crystallography and recombinant antibodies to uncover workings of an elusive molecule central to human health Credit: Salk Institute LA JOLLA–(February 17, 2021) In structural biology, some molecules are so unusual they can only be captured with a unique set of tools. That’s precisely how a multi-institutional research team led by Salk […].

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BioSpace Global Roundup: Imcyse Snags $25.8 Million in Financing and More News

BioSpace

Biopharma and life sciences companies from around the globe provide updates on their pipelines and businesses.

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Silencing the alarm

Scienmag

An enzyme in the saliva of certain insects prevents their food plants from warning neighboring plants of an attack Credit: Nick Sloff, Penn State UNIVERSITY PARK, Pa. — Like a scene from a horror movie, tomato fruitworm caterpillars silence their food plants’ cries for help as they devour their leaves. That is the finding of […].

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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‘Urgent action needed’ as NHS faces growing waiting lists

Pharma Times

A growing number of patients are waiting 52 weeks or more for hospital treatment

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Immunome Isolates Antibodies Capable of Neutralizing SARS-CoV-2 Variants

BioSpace

Shares in the company shot up 212.6% following the news it had isolated the potentially variant-neutralizing antibodies.

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Study examines aspirin and statin use among older Americans

Scienmag

An analysis published in the Journal of the American Geriatrics Society indicates that while adults aged 75 years and older do not benefit from taking aspirin to prevent cardiovascular disease, many do so on a regular basis. Also, although statins are known to help prevent heart problems in older adults who have experienced a cardiovascular […].

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BeiGene Seeks FDA Approval for BTK Inhibitor, Strikes Oncology Deal with BITT

BioSpace

BeiGene’s Bruton’s kinase inhibitor Brukinsa (zanabrutinib) could be on its way for regulatory approval as a potential treatment for Waldenström’s macroglobulinemia (WM), a type of non-Hodgkin lymphoma.

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.