Thu.Mar 24, 2022

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As biotech retreats, gene therapy companies retrench and redraw plans

Bio Pharma Dive

At least nine biotechs working in cell or gene therapy have announced layoffs, cost cuts or restructured their research since December — restructurings that have coincided with a stock market downturn.

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Passing the trash

World of DTC Marketing

I’ve seen some new energy and thinking taking root in some big pharma companies. Still, I’m also seeing some recycled executives show up at other companies when they should have been removed permanently from the industry. John worked for a division of a major pharma company in Cambridge. He came from the salesforce, and his mentality was simple; marketing supports sales.

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Novartis wins FDA OK for radiopharmaceutical drug, cashing in on Endocyte deal

Bio Pharma Dive

The approval of Pluvicto for prostate cancer is a notable step forward for the field of radiopharmaceutical therapy and validates the Swiss drugmaker's $2.1 billion buyout of Endocyte in 2018.

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Moderna’s Australian mRNA manufacturing facility set to become operational in 2024

BioPharma Reporter

Moderna has finalized a strategic partnership with the Australian government to build an mRNA manufacturing facility in Melbourne: which is expected to produce up to 100 million mRNA respiratory vaccine doses annually.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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FDA, as expected, rejects Lilly and Innovent immunotherapy in a signal to drugmakers

Bio Pharma Dive

The regulator demanded the partners run another clinical trial to support approval of sintilimab, a decision that could have ripple effects for the development and cost of cancer immunotherapies in the U.S.

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UK’s first digital health training programme for all NHS frontline staff

Pharma Times

The platform to build a digital-ready frontline workforce will be available to all NHS and social care staff

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Poolbeg signs AI deal to advance human challenge data

Pharma Times

Collaboration will focus on AI analysis of flu progression, immune responses and the development of new vaccines

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UK offers strong research base for ATMPs – but needs to catch up on manufacturing, says report

BioPharma Reporter

The Cell and Gene Therapy Catapult (CGT Catapult) has today published the âNational Cell and Gene Therapy Vision for the UKâ, a document outlining recommendations for a national strategy for the adoption of cell and gene therapies.

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GSK partners LifeMine on fungi-derived medicines

pharmaphorum

GlaxoSmithKline has thrown its financial and drug development weight behind LifeMine Therapeutics, a US startup that aims to find new therapeutics from fungi – widely regarded as an underexplored resource of biologically-active compounds. There’s a rich history of finding useful medicines from fungi, from the antibiotic penicillin to immune suppressant cyclosporine and cholesterol drug lovastatin.

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NYU Abu Dhabi researchers discover a mysterious, new type of wave in the Sun whose speed defies explanation

Scienmag

Abu Dhabi, UAE: Researchers from NYU Abu Dhabi’s (NYUAD) Center for Space Science have discovered a new set of waves in the Sun that, unexpectedly, appear to travel much faster than predicted by theory. Credit: NYU Abu Dhabi Abu Dhabi, UAE: Researchers from NYU Abu Dhabi’s (NYUAD) Center for Space Science have discovered a new […].

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Janssen initiates psoriasis trial to bridge racial gaps in care

Outsourcing Pharma

The pharmaceutical company's clinical study is intended to examine critical gaps in care for people of color living with moderate to severe plaque psoriasis.

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Development of stretchable and printable free-form lithium-ion batteries

Scienmag

A Korean research team has developed a soft, mechanically deformable, and stretchable lithium battery which can be used in the development of wearable devices, and examined the battery’s feasibility by printing them on clothing surfaces. The research team, led by Dr. Jeong Gon Son from the Soft Hybrid Materials Research Center at the Korea Institute […].

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Novartis gets first OK for radioligand Pluvicto in prostate cancer

pharmaphorum

Novartis has been steadily investing in radiopharmaceuticals over the last few years, and one of those deals has just paid off with an FDA approval for Pluvicto, the first targeted radioligand therapy for prostate cancer. Pluvicto (lutetium Lu 177 vipivotide tetraxetan) – formerly known as 177Lu-PSMA-617 – has been cleared in the US for previously-treated patients with PSMA-positive metastatic castration-resistant prostate cancer (mCRPC), a group with limited treatment options.

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Rapid glacial advance reconstructed during the time of Norse occupation in Greenland

Scienmag

Boulder, Colo., USA: The Greenland Ice Sheet is the second largest ice body in the world, and it has the potential to contribute significantly to global sea-level rise in a warming global climate. Understanding the long-term record of the Greenland Ice Sheet, including both records of glacial advance and retreat, is critical in validating approaches […].

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Ukraine war dramatically impacting global clinical development: Phesi

Outsourcing Pharma

The companyâs analysis of clinical research activity in the region shows the conflict will have long-lasting effects that reach beyond the countryâs borders.

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Improving self-driving car reliability with electromagnetic wave absorption and shielding technology!

Scienmag

A research team led by Dr. Sang-Bok Lee and Byeongjin Park in the Department of Functional Composites at the Korea Institute of Materials Science(KIMS) succeeded in developing the world’s first ultra-thin composite film. This film does not reflect electromagnetic waves for 5G communication but absorbs more than 90% of it. The technology can solve the […].

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Conducting successful commercial research in a primary care setting

pharmaphorum

The primary care setting offers huge potential for commercial research. This was, and still is being, demonstrated through the UK’s COVID-19 vaccine research successes. But tapping into that potential requires companies to understand and to plan for primary care. In this session, we will unpick some of the common challenges faced by companies when initiating research in this setting.

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Tropical peatland, sea level rise and climate change

Scienmag

Tropical peatlands are one of the most efficient carbon sinks. The flipside is that they can become massive emitters of carbon if they are damaged, for instance by land use change, degradation or fire. This can lead to faster climate warming. In research led by the University of Göttingen, researchers show how peatland in the […].

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Cloudbyz & Salesforce: Sales Enablement Workshop

Cloudbyz

Cloudbyz and Salesforce Join Together for Clinical Trial Solutions Partner Enablement Event. Tuesday, March 22nd Cloudbyz joined Salesforce at their Chicago offices for a joint sales enablement event discussing both the clinical trial space and how Salesforce and Cloudbyz solutions help life science organizations get their products to market faster.

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Birds are laying their eggs earlier, and climate change is to blame

Scienmag

Spring is in the air. Birds are singing and beginning to build their nests. It happens every year, like clockwork. But a new study in the Journal of Animal Ecology shows that many species of birds are nesting and laying eggs nearly a month earlier than they did a hundred years ago. By comparing recent […].

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Intouch Scores Two PM360 Greatest Creators Awards

Intouch Solutions

We’ve been getting a lot of attention for our creative work lately — from our PM360 Pharma Choice Award wins last month , to being named a 2021 Top 5 Creative Agency by lauded creative magazine Lurzer’s Archive to Intouch chief creative officer Susan Perlbachs being tapped to judge submissions for the 2022 Clio Health awards, we are making creative waves.

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Rescued Victorian rainfall data smashes former records

Scienmag

Record-breaking Victorian weather has been revealed after millions of archived rainfall records dating back nearly 200 years were rescued by thousands of volunteers during the first Covid-19 lockdown. Credit: Met Office Record-breaking Victorian weather has been revealed after millions of archived rainfall records dating back nearly 200 years were rescued by thousands of volunteers during […].

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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Triall Partners With Crucial Data Solutions to Realize the World’s First End-to-End eClinical Platform Powered by Blockchain

Crucial Data Soutions

Triall will onboard the globally deployed eClinical platform of Crucial Data Solutions into the Triall ecosystem, offering clinical researchers around the world with access to Triall’s blockchain APIs that strengthen clinical trial data integrity, auditability, and interoperability. MAARSSEN, Netherlands, March 24, 2022 (GLOBE NEWSWIRE) — Triall, a tokenized platform for blockchain-enabled clinical trial technology, has partnered with Crucial Data Solutions (CDS), an eClinical softwa

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The hidden issue of anorexia in pregnancy – world first guidelines for management

Scienmag

THE HIDDEN ISSUE OF ANOREXIA IN PREGNANCY – MONASH-LED STUDY PROVIDES WORLD FIRST GUIDELINES FOR MANAGEMENT Pregnant women with anorexia are at greater risk of having a stillbirth, underweight baby or pre-term birth, yet there are no clear guidelines for how doctors should manage the condition, according to a Monash University-led study. Led by Professor […].

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Big data and how it can change the game in pharma: the pharmaphorum podcast

pharmaphorum

In the latest episode of the pharmaphorum podcast, editor in chief Jonah Comstock speaks with Miruna Sasu, chief strategy officer of COTA and long-time pharma vet– before joining COTA last year, she headed up J&J’s Clinical Trial Feasibility and Advanced Analytics Team and led the Digital Health and Innovation Team at Bristol Myers Squibb.

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New Fermi arcs could provide a new path for electronics

Scienmag

Newly discovered Fermi arcs that can be controlled through magnetism could be the future of electronics based on electron spins. These new Fermi arcs were discovered by a team of researchers from Ames Laboratory and Iowa State University, as well as collaborators from the United States, Germany, and the United Kingdom. During their investigation of […].

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Are TikTok Food Trends Changing the Landscape of the Food Industry?

XTalks

Users sharing foods from restaurants or personal recipes on social media is nothing new, but TikTok food trends are taking this phenomenon to another level. This week, the hashtag for “food” had amassed a whopping 268 billion views on the popular video sharing app, while “#recipes” and “#restaurant” garnered an impressive 9.1 billion and 6.9 billion, respectively.

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Keeping the light from fading

Scienmag

Ikoma, Japan – Scientists from Nara Institute of Science and Technology created a new approach to compensate for variations in illumination while scanning cathedral stained-glass windows. This work may be applied to other objects of cultural significance to help capture their colors in the most lifelike way. Credit: Takuya Funatomi Ikoma, Japan – Scientists from […].

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Data shows Netherlands best base for international pharmaceutical companies

Drug Discovery Today

The ranking was calculated on cost and time efficiencies and United States was shown to be the most efficient jurisdiction on speed of business whereas Brazil, South Korea and China scored less favorably

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Unstable molecule clicks with synthetic strategy

Scienmag

The elements on the periodic table of elements are listed in ways that emphasize certain relationships. There are families, periods (the horizonal rows) and groups (the vertical columns). The elements within each of these groupings exhibit some commonalities. Credit: Figueroa Lab Group, UC San Diego / Curtis Moore, Ohio State University The elements on the […].

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.