Fri.Aug 14, 2020

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CureVac grabs $213M in US IPO, adding to year's record pace

Bio Pharma Dive

Biotech companies have raised nearly $10 billion from 45 initial public offerings this year, with CureVac's fueling the development of an experimental coronavirus vaccine.

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Species-specific Demands Trigger New R&D Areas in Animal Healthcare Market, Notices a New FMI Study

Pharma Mirror

Animal feed represents the most profitable product type segment, presenting multiple investment opportunities for animal healthcare market operators. Top selling potential of animal feed additives is attributed to a growing focus on disease outbreak prevention rather than on curing disease afflicted animals. Animal healthcare market in China and Japan is especially observing robust demand growth.

Marketing 130
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Europe, trailing US, UK, reaches first coronavirus vaccine deal

Bio Pharma Dive

Both the U.S. and U.K. have aggressively signed preorder deals with vaccine developers. An agreement with AstraZeneca is the EU's first.

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QBiotics Announces Clinical Collaboration with MSD Targeting Unresectable Melanoma

Pharma Mirror

QBiotics Group Limited (QGL), a life sciences company developing novel anticancer and wound healing pharmaceuticals, is pleased to announce that it has entered into an agreement with MSD (tradename of Merck & Co., Inc., Kenilworth, NJ, USA), to evaluate use of its lead molecule tigilanol tiglate, in combination with Keytruda(R) (pembrolizumab) in patients with unresectable.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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UK’s second go at a contact tracing app heads for pilot study

pharmaphorum

After ditching its home-grown attempt at a coronavirus contact-tracing app for smartphones, the UK is ready to start pilot trials of a second version based on a platform developed by Apple and Google. The new NHS Test and Trace app is intended to be used as an add-on to the controversial national and local contact-tracing service, and was due to start initial trials yesterday on the Isle of Wight and among a group of NHS volunteers.

Trials 116
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Evidence of positive impact of pharmacists on patient safety published by FIP

Pharma Mirror

The positive impacts of pharmacists in supporting medication without harm are described in a new publication from the International Pharmaceutical Federation (FIP) released today. The World Health Organization reports that one in four patients is harmed by the care they receive in primary and ambulatory care settings, including harm from medicines. It estimates the global.

Medicine 130

More Trending

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How to Stay Food Safety Compliant and Be Inspection Ready, Even During a Pandemic

XTalks

While the COVID-19 pandemic has disrupted the way consumers shop and food manufacturers operate, food safety remains a top priority for all stakeholders. The entire food supply chain is committed to meeting this expectation despite the fact that our new normal is changing from day-to-day. Many companies have successfully transitioned their meetings, events and even happy hours to virtual platforms to meet social distancing recommendations.

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What Happens When 3rd-Party Cookies Expire?

Pharma Marketing Network

2022 will usher in the demise of third-party cookies—that means pharma brands must change their approach to targeting and measurement. For decades, the third-party cookie has been a core component of any digital marketing strategy, allowing advertisers to deliver targeted ads and measure their effectiveness. However, with increased consumer privacy concerns and regulations, third-party cookies are set to expire by 2022.

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Gene variants help explain connection between skin disorder and food allergy risk

Scienmag

Discovery could lead to new screening tests and potential treatments Credit: Cincinnati Children’s Two common variants in the KIF3A gene increase the risk of young children having a dysfunctional skin barrier and developing the skin condition atopic dermatitis. This, in turn, can allow environmental exposures to more easily cross the skin barrier and contribute to […].

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Coronavirus pharma news roundup – 14/08/20

pharmaphorum

Catch up on the latest coronavirus vaccine and digital tech news in our roundup of this week’s biggest stories. Consumer advocacy group Public Citizen has slammed the amount Moderna is charging the US for the mRNA-1273 vaccine, saying that as taxpayer money had funded 100% of the work done to bring it to market the US is “paying twice” for the shot.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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AstraZeneca ships first doses of flu vaccine

Pharma Times

Company will manufacture over 25% more doses than previously planned

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UK medical journals spar over breast cancer screening study

pharmaphorum

Screening women for breast cancer in their 40s rather than their 50s could save lives, say the authors of a new Lancet Oncology study, although that finding has been challenged by other experts. Lowering the age that women start to routinely get mammograms was associated with a relative reduction in breast cancer mortality without leading to ‘over-diagnosis’ – in other words detecting minor changes that may not turn into full-blown cancers – according to the scientists.

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Top Russian doctor quits over questionable ethics that rushed through coronavirus vaccine

The Pharma Data

Photo by Senior Airman Areca Wilson. Professor Alexander Chuchalin has quit the Russian Health Ministry’s ethics council due to the quick approval process for the country’s coronavirus vaccine. Many countries have criticised Russia pursuit for a COVID-19 cure, which has skipped Phase 3 trials before giving the vaccine regulatory approval. It seems Chuchalin had tried and failed to block its registration on safety grounds.

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Poor hygiene is significant risk for antimicrobial-resistant bacteria colonization

Scienmag

Credit: WSU PULLMAN, Wash. – Scientists have found clear indicators for how the interaction of poor hygiene and antibiotic use contribute to the colonization of antimicrobial-resistant (AMR) bacteria in humans, a problem that contributes to hundreds of thousands of deaths annually. The findings by researchers at Washington State University’s Paul G.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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UK inks further coronavirus vaccine deals

Pharma Times

Deals agreed with Janssen and Novavax for another 90 million doses

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Remains of 17th century bishop support neolithic emergence of tuberculosis

Scienmag

Bishop Peder Winstrup of Lund, Sweden passed away in the winter of 1679 at the age of 74 and was interred in a crypt at Lund Cathedral; three centuries later, his astonishingly well-preserved remains provide insights to the origins of tuberculosis Credit: Orf3us / CC BY-SA ([link] When Anthropologist Caroline Arcini and her colleagues at […].

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Conran Design Group names Christina Falzano as MD for the US

pharmaphorum

Global branding firm Conran Design Group has appointed former Wolff Olins chief operating officer Christina Falzano as its US managing director. She brings over 20 years’ experience in brand strategy and marketing to her new role at the Havas -owned communications agency. Before joining brand consultancy Wolff Olins – where she oversaw work for Google , Wikipedia, Uber, Showtime and Spotify, Falzano served as managing director for Brand Union (now merged into Superunion).

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People power and satellites help scientists study climate impacts on Antarctic seals

Scienmag

Credit: Credit: Ursala Rack A New Zealand-led international study of the crabeater seal population in Antarctica aims to understand environmental impacts on one of the southern-most mammals in the world. With funding from The Pew Charitable Trusts, University of Canterbury (UC) scientists have been using satellite images of Antarctica and the power of citizen science […].

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Novo Nordisk resumes late-stage haemophilia trials

Pharma Times

Clinical trial programme resumes after safety concerns

Trials 119
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Clinical Trials of Coronavirus Drugs Are Taking Longer Than Expected

NY Times

Antibody trials sponsored by Regeneron and Eli Lilly are off to a slow start because of a dearth of tests, overwhelmed hospitals and reluctant patients.

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A method has been developed to study extreme space weather events

Scienmag

Credit: SDO/AIA +SOHO/LASCO COR1+COR2 Scientists at Skolkovo Institute of Science and Technology (Skoltech), together with colleagues from the Karl-Franzens University of Graz & the Kanzelhöhe Observatory (Austria), Jet Propulsion Laboratory of California Institute of Technology (USA), Helioresearch (USA) and Space Research Institute of the Russian Academy of Sciences (Russia) developed a method to study fast […].

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What Happens When 3rd-Party Cookies Expire?

Pharma Marketing Network

2022 will usher in the demise of third-party cookies—that means pharma brands must change their approach to targeting and measurement. For decades, the third-party cookie has been a core component of any digital marketing strategy, allowing advertisers to deliver targeted ads and measure their effectiveness. However, with increased consumer privacy concerns and regulations, third-party cookies are set to expire by 2022.

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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Historical redlining linked to premature births, lower birth weight babies

Scienmag

Study of three California cities finds that past discriminatory housing practices may be impacting maternal and infant health today Past discriminatory housing practices may play a role in perpetuating the significant disparities in infant and maternal health faced by people of color in the U.S., suggests a new study by researchers at the University of […].

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Top Ten most popular articles on Pharmafile.com this week

The Pharma Data

The top 10 news stories this week once again focus on coronavirus treatments and vaccines, as President Putin announced that Russia has granted regulatory approval for a COVID-19 vaccine while researchers at the University of Oxford have said that hydroxychloroquine could be beneficial to coronavirus patients, despite a general lack of evidence for its effectiveness.

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Newly identified gut cells nurture lymph capillaries

Scienmag

Understanding the mechanisms that impair lymphatics growth and fat digestion in the small intestine Credit: IBS You have just enjoyed a delicious summer BBQ. After approximately eight hours, food molecules reach your small intestine, where specialized lymph capillaries, called lacteals, absorb fat nutrients. Lacteals are different from other lymphatics, as they continue to regenerate during […].

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Parents urged to stay up-to-date with children's vaccinations

The Pharma Data

Image copyright. Getty Images. Parents are being urged to make sure their children are up-to-date with all their routine vaccinations. The Local Government Association said high vaccine uptake could prevent infections and stop pressure being piled on the NHS. The childhood vaccination programme is continuing as normal while jabs given in school are being rescheduled.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Is the COVID-19 virus pathogenic because it depletes specific host microRNAs?

Scienmag

UAB and Polish researchers propose that the COVID-19 virus acts as a microRNA “sponge” to deplete miRNA levels in ways that aid viral replication and stymie the host immune response. Credit: UAB BIRMINGHAM, Ala. – Why is the COVID-19 virus deadly, while many other coronaviruses are fairly innocuous and just cause colds? A team of […].

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Novavax and Janssen commit 90 million COVID-19 vaccine doses to UK Government with two new deals

The Pharma Data

The UK Government has signed a new deal with Johnson & Johnson and Novavax to secure 90 million orders of their vaccine candidates to protect against COVID-19 infection. . One of the announced deals was to reserve 30 million doses of Ad26.COV2.S, the COVID-19 vaccine candidate developed by Janssen, the pharmaceutical subsidiary of J&J, for not-for-profit emergency pandemic use.

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German-Argentinean doctoral program bears first fruits

Scienmag

Credit: Instituto de Agrobiotecnología del Litoral The programme is funded by the German-Argentinean University Centre (DAHZ-CUAA). Dr. Regina Mencia from Argentina was the first doctoral student to complete her doctorate under this programme at the beginning of this year. The success of her German-Argentinean cooperation has now been crowned by a joint publication in the […].

Doctors 63
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AstraZeneca ships first doses of flu vaccine

The Pharma Data

Company will manufacture over 25% more doses than previously planned. AstraZeneca has announced the first shipment of Flumist Quadrivalent vaccine doses have been sent to the US for the upcoming influenza season. Flumist is currently the only nasal-spray flu vaccine and is indicated for use in individuals aged two through to 49. The US Centres for Disease Control and Prevention (CDC) has recently highlighted the importance of flu vaccination rates for the 2020-21 season, in a b

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.