Sat.Mar 20, 2021 - Fri.Mar 26, 2021

Roche stops giving Huntington's disease drug in closely watched study

Bio Pharma Dive

A disappointing recommendation from outside data reviewers raises doubts about the DNA-targeting drug's benefits and puts pressure on Roche's partner, Ionis Pharmaceuticals

DNA 250

The right balance in DTC: Tv versus digital ads

World of DTC Marketing

SUMMARY: Television remains the most important medium for healthcare advertising , accounting for 54.7% of all spend in 2018, far higher than television’s 30.8% share of the advertising market as a whole.


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U.S. Health Officials Question AstraZeneca Vaccine Trial Results

NY Times

According to federal officials, an independent panel of medical experts said the promising results announced by the company on Monday may have relied on “outdated information.”.

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Life-sciences pros believe in potential of AI, blockchain: survey

Outsourcing Pharma

A survey by the Pistoia Alliance indicates most professionals believe the tech can accelerate R&D, but companies are stymied by a skills gap and data bias. Markets & Regulations

Bristol Myers gets late-stage win in test of new type of immunotherapy

Bio Pharma Dive

When given together with Opdivo, Bristol Myers' new drug kept skin cancers from progressing, a rare clinical victory for a combination of immunotherapies that puts the pharma a step ahead of several rivals

Drugs 233

Profiteering off a Covid vaccine

World of DTC Marketing

SUMMARY: Johnson & Johnson and AstraZeneca publicly committed to not profiting off their products during the pandemic; Pfizer and Moderna made no such pledge and are already planning ways to make more money from their Covid vaccines.

Scientists develop new platelet-based formulation for combination anticancer therapy


Credit: WEI Wei Tumor targeting and intratumoral penetration are long-standing issues for cancer therapeutics.

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Drugmakers flock to Vineti's fix for a cell, gene therapy problem

Bio Pharma Dive

A group of drug companies, including Novartis, Takeda and Roche's Genentech, have agreed to collaborate with Vineti to usher in new identification standards for complex medicines

Can ROI ever be used with patient-centric?

World of DTC Marketing

SUMMARY: The goal of business is to maximize profits for shareholder returns but when a company that serves the public good pays CEOs millions of dollars in compensation while having among the highest profit margins within ANY industry I would argue that something is dreadfully wrong. The U.S.

New porous material promising for making renewable energy from water


Credit: Thor Balkhed/LiU One prospective source of renewable energy is hydrogen gas produced from water with the aid of sunlight.

Novartis’ radioligand therapy meets phase 3 prostate cancer trial target

Pharma Phorum

Novartis’ radioligand therapy Lu-PSMA-617 has met its target in prostate cancer, as its $2.1 billion acquisition of specialist pharma Endocyte looks to have been justified. .

US stops rollout of Lilly's first COVID-19 antibody over variant concerns

Bio Pharma Dive

Treatments from Lilly and Regeneron that combine two different antibodies should be used instead, according to health officials

Drug price negotiations on the horizon

World of DTC Marketing

SUMMARY: Democratic lawmakers are weighing whether to include drug pricing measures that could extract tens of billions of dollars from the industry. Something is coming. We’re just not sure when,” said one drug industry lobbying source.

Drugs 157

Researchers discover why cold induces tooth pain and hypersensitivity — and how to stop it


Health tech and digital transformation lessons from the NHS

Pharma Phorum

In the year since the UK went into its first lockdown to limit the spread of COVID-19 the country’s health service has undergone an unprecedented digital transformation. .

AstraZeneca, Oxford vaccine prevents COVID-19 in big US study amid controversy overseas

Bio Pharma Dive

A two-shot regimen was 79% effective at protecting people from COVID-19, which should support the fourth clearance of a vaccine in the U.S. and calm safety concerns abroad

The pharmaceutical’s industry biggest challenge

World of DTC Marketing

QUICK READ: If you start to lose key people, you won’t be able to keep the business you do have, and things will go from bad to worse. Companies who see their good employees as “replaceable” are wrong. Good employees are not replaceable.

Neutrons reveal unpredicted binding between SARS-CoV-2, hepatitis C antiviral drug


Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. of Energy Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.

Pfizer begins clinical trials of COVID-19 antiviral pill

Pharma Phorum

Pfizer has begun clinical development of an antiviral pill against COVID-19, which could be prescribed to patients at the first sign of infection.

Moncef Slaoui, who led US Warp Speed effort, accused of sexual harassment

Bio Pharma Dive

Slaoui was fired as board chair of Galvani Bioelectronics following an investigation by the company's majority shareholder GlaxoSmithKline, which said the claims were substantiated


New COVID-19 Findings: Oral Transmission and the UK Variant’s Reproduction Rate


What has been learned about SARS-CoV-2, the virus that causes COVID-19, in only about 15 months, is truly a historical scientific achievement. And new information continues to come in


Researchers harvest energy from radio waves to power wearable devices


Credit: Larry Cheng, Penn State From microwave ovens to Wi-Fi connections, the radio waves that permeate the environment are not just signals of energy consumed but are also sources of energy themselves.

Cache of 29 Million AstraZeneca Doses in Italy Raises E.U. Suspicions

NY Times

The company has been at loggerheads with the bloc over vaccine supply shortages and faces stringent export restrictions. Coronavirus (2019-nCoV) Vaccination and Immunization International Trade and World Market Stockpiling Drugs (Pharmaceuticals) AstraZeneca PLC European Union Italy

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Slaoui steps down from two more biotechs after harassment claim

Bio Pharma Dive

The former Warp Speed leader resigned from leadership roles at VaxCyte and Centessa Pharmaceuticals after being fired by GlaxoSmithKline over harassment allegations


Isolator webinar series continues!

Syntegon Technology Pharma Blog

Liquid Dosage Andrey Yermakovich barrier systems Isolator Laura Moody Matthias Angelmaier Project Management Qualification/Validation Stefan Schuh Syntegon


Stanford economist and others assess aquaculture’s promise and peril


Credit: Created by Overview, source imagery by Maxar Technologies Despite aquaculture’s potential to feed a growing world population while relieving pressure on badly depleted oceans, the industry has been plagued by questions about its environmental impacts.

AstraZeneca’s Covid-19 Vaccine Is Found to Be 79% Effective in U.S. Study

NY Times

The company is preparing to apply for emergency authorization from the Food and Drug Administration. But the shot may not be needed in the United States.

FDA won't review Novo diabetes drug in latest case of regulatory pushback

Bio Pharma Dive

Novo Nordisk said the FDA requested more data before starting review for a high dose of the Danish company's treatment semaglutide, extending a string of recent setbacks for drugmakers in the U.S.

Drugs 165

Leading Approaches to Extracellular Vesicle Therapies


Two financings – and a surprise stock bump – in three days for the some of the most advanced extracellular vesicle (EV) companies show investors are champing at the bit to see the technology unleashed


Sealing fistulas with regenerative immiscible bioglue


Credit: POSTECH A Korean research team has recently developed an innovative vesico-vaginal fistula treatment method using the mussel adhesive protein (MAP) that can effectively seal fistulas in organs even when exposed to urine.

The Brexit deal; shot in the arm or kick in the teeth for the pharma sector?

Pharma Phorum

The UK Government and EU Commission trumpeted their Brexit trade deal, struck at the end of December, as ‘comprehensive’, the ‘biggest yet’ But a closer inspection of the EU-UK Trade and Cooperation Agreement (TCA) renders these statements largely illusory for the pharma sector.

AstraZeneca, under fire, tries to repair image with new vaccine data

Bio Pharma Dive

Updated results show the vaccine is only slightly less effective than AstraZeneca originally reported. But an unusual break with a study committee may damage perception of the shot

BrainStorm Trial Shows Promising Top-Line Results for Progressive Multiple Sclerosis


The study involved observations in neurologic function, cognition and biomarkers in three repeated administrations of Nurown®, which were given two months apart

Shining a healing light on the brain


Credit: (Image by Zhaowei Chen/Argonne National Laboratory.) Scientists make pivotal discovery of method for wireless modulation of neurons with X-rays that could improve the lives of patients with brain disorders. The X-ray source only requires a machine like that found in a dentist’s office.

GSK flags new data suggesting a stark decline in routine adult vaccinations in the US

BioPharma Reporter

The pharma company and the CDC are recommending that adults continue routine vaccination during the COVID-19 pandemic to reduce future vaccine-preventable disease (VPD) outbreaks and overall strain on the healthcare system. Markets & Regulations

Regeneron joins Lilly in proving lower-dose antibody drugs can thwart COVID-19

Bio Pharma Dive

The findings could help boost the supply and reach of Regeneron's COVID-19 antibody drug, which, despite limited use, is now backed by convincing data showing it can prevent hospitalization

Boston Scientific to Pay $189 Million in Vaginal Mesh Lawsuit


Boston Scientific’s settlement was not an admission of misconduct or liability. In a brief statement cited by Reuters, the company said the financial agreement was in its shareholder’s best interest