Sat.Apr 23, 2022 - Fri.Apr 29, 2022

FDA clears Pfizer to restart Duchenne gene therapy trial, with new safeguards

Bio Pharma Dive

The regulator has asked Pfizer to closely monitor patients in a hospital setting for a week as part of a deal to end a study suspension that's lasted more than four months

Cardiologists say information on wearables isn’t always useful.

World of DTC Marketing

Gadget firms — starting with Apple and now Fitbit, which Google owns — are selling wearable devices that check heartbeat rhythms and alert users when something is out of sync, according to KHN.com.

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Living near fast food restaurants in South Asia may increase risk of Type 2 diabetes

Scienmag

Globally, the prevalence of type 2 diabetes mellitus (T2DM) is increasing.

Pharma can now track the most relevant patent info – fast and at scale

Pharma R&D Today

Since its initial release in January 2021, AI-fueled Patent Expansion in Reaxys has won the respect of pharmaceutical companies trying to stay ahead of their competitors by keeping track of the latest patents around drug discovery and new therapeutics.

2022 Research: The Rapid Rise of Ocean Freight Visibility

Download this a benchmark study from FourKites and The Journal of Commerce exploring how international shippers’ usage of global supply chain visibility technology has evolved since the onset of global disruptions caused by COVID-19.

Solid Bio joins slate of biotech layoffs, shedding 35% of its workforce

Bio Pharma Dive

The company is the latest in a growing list of gene therapy developers to restructure and cut jobs during an industry-wide downturn

More Trending

Breakthrough in how buildings can promote health and well-being

Scienmag

Having understood the ill-effects if sick building syndrome and the need to better conserve energy by incorporating green features, architects are also utilizing certain elements of an architectural design system shown to reduce stress, improve sleep, promote physical and mental health, thereby improving the quality of life for its inhabitants.

Smartphone-based skin cancer diagnostic certified for use in UK

Pharma Phorum

An artificial intelligence-powered digital tool for diagnosing skin cancers developed by Skin Analytics has been cleared in the UK as a Class IIA medical device, setting up broader use of the technology in patient assessments.

How a surprise finding made an Alnylam study one of biotech's most 'polarizing' trials

Bio Pharma Dive

A study testing Alnylam's drug Onpattro in a deadly heart condition was once seen as a sure bet. Now the trial is the source of much debate, and its outcome could influence how future treatments for the disease are developed

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Valneva and Pfizer report positive Phase 2 data for Lyme disease vaccine in children

BioPharma Reporter

Valneva and Pfizer report positive Phase 2 pediatric data for their Lyme disease vaccine candidate, VLA15: and now plan to include this population in an upcoming Phase 3 trial. Bio Developments

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An Innovative & Creative Problem Solver Approach to Selling in the Medical Device Space

Speaker: Steve Goldstein, Sales Leader

Currently in sales or involved in a business that depends on strong sales results? Join Steve Goldstein, Sales Success Coach, Motivational Speaker and Medical Device Sales Leader from Gold Selling LLC. You will absorb critical strategies to become a trusted partner in greater sales success.

What do jelly and sand have in common?

Scienmag

Tokyo, Japan – Researchers from Tokyo Metropolitan University have identified key similarities between the behavior of granular materials and melting gels.

Digital interventions cut heart failure mortality, study shows

Pharma Phorum

An analysis of 10 clinical trials of digital health interventions targeted at patients recently hospitalised for acute heart failure has found they improve outcomes compared to standard care.

AbbVie's first shot at Vertex misses, but it's not abandoning cystic fibrosis

Bio Pharma Dive

Executives on Friday said that the company's three-drug therapy, a possible threat to Vertex's top-selling medicine Trikafta, didn't meet expectations in a key study. A new combination could start testing next year, however

Overcoming the 4 leading barriers to cardiovascular disease patient recruitment

Clairnes

The post Overcoming the 4 leading barriers to cardiovascular disease patient recruitment appeared first on Clinical Trial Recruitment & Management Services. Blog Cardiovascular disease

Mandatory COVID Vaccination Policy Template

The federal government is developing a rule requiring employers with more than 100 employees ensure their workers are vaccinated or produce a negative COVID test weekly before entering the workplace. So, what can your organization do to prepare? Get Paycor’s COVID Vaccination Policy Template to help communicate important details to your employees.

Glimpse inside a graphene sandwich

Scienmag

Since the first successful fabrication of a two-dimensional structure of carbon atoms about 20 years ago, graphene has fascinated scientists. A few years ago, researchers discovered that two layers of graphene, slightly twisted against each other, can conduct electric current without loss.

New long COVID study highlights key symptoms

Pharma Times

Women, those who are obese and those on mechanical ventilation are all more likely to suffer from the effects long-term COVID-19

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Bristol Myers wins FDA approval for first drug to treat inherited heart condition

Bio Pharma Dive

Bristol Myers paid $13 billion to acquire the drug's maker, MyoKardia, and expects a top-selling medicine. But a tricky dosing regimen, as well as safety concerns, could challenge the pharmaceutical giant's lofty forecast

Understanding the microbiome as an ‘overlooked critical organ’

Pharma Phorum

Compared to a ‘critical organ’ that had been largely ignored, companies working to develop microbiome-based therapies believe there is untapped potential in the area.

Solar beats nuclear at many potential settlement sites on Mars

Scienmag

The high efficiency, light weight and flexibility of the latest solar cell technology means photovoltaics could provide all the power needed for an extended mission to Mars, or even a permanent settlement there, according to a new analysis by scientists at the University of California, Berkeley.

Adding CACS to Primary Prevention Risk Estimation Models

JAMA Internal Medicine

Less is More

Two biotechs set out to end sector's IPO drought

Bio Pharma Dive

HilleVax and Belite Bio could soon become the first biotechs to go public in almost two months, representing a key test of investors’ willingness to support emerging life sciences companies

AstraZeneca plans new US R&D hub as revenues rocket

Pharma Phorum

AstraZeneca has revealed plans to set up a new strategic R&D hub in Cambridge, Massachusetts as it reported a massive increase in first-quarter revenues, driven by COVID-19 and oncology drugs and heart failure therapy Farxiga.

Meat consumption must fall by at least 75 percent

Scienmag

Every EU citizen consumes around 80 kilograms of meat per year. But every juicy steak, every delicious sausage has a price that we do not pay at the counter, because livestock farming damages the climate and the environment. Ruminants for instance produce methane, which accelerates global warming.

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How PurePlus Upcycles Fruit into Climate-Friendly Candies

XTalks

Los Angeles-based startup PurePlus launched its first consumer brand, Faves, in 2021 as a sustainable alternative to the popular candy brand Startburst.

After setbacks, a gene therapy company mulls a sale

Bio Pharma Dive

Sio Gene Therapies, formerly known as Axovant, said it's focused on conserving cash, and has decided to significantly reduce its workforce and terminate licensing agreements on its last two pipeline programs

Merck makes $3.2bn from COVID-19 drug Lagevrio in Q1

Pharma Phorum

Orders for Merck & Co’s oral antiviral for COVID-19 helped to swell the drugmaker’s first quarter revenues by a massive 50%, although underlying growth was also strong. Lagevrio (molnupiravir) added $3.2 billion to Merck’s top line of $15.9

Give bidi cigarette rollers a voice to find new jobs, researchers say

Scienmag

India’s bidi cigarette workers need to be at the heart of discussions about finding alternatives to working in the tobacco industry, according to a new study.

Which pharmaceutical companies have the most spray dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most spray dosed drugs. For a different perspective, see the most popular dosage types. The companies with the most spray dosed drugs…. The post Which pharmaceutical companies have the most spray dosed drugs?

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FDA sets back Novartis' best chance at a COVID-19 drug

Bio Pharma Dive

The agency indicated another trial of the drug, developed by Molecular Partners, will be needed. But whether such a study is doable is yet to be determined, according to Novartis' CEO Vas Narasimhan

Trials 225

Google, Sanofi back UK biotech OMass’ $100m second round

Pharma Phorum

OMass Therapeutics has raised an impressive $100 million in a Series B financing that is said to be the largest ever for a UK biotech focusing on small-molecule drug development.

New model for antibacterial mechanism

Scienmag

UPTON, NY—Biologists at the U.S. Department of Energy’s Brookhaven National Laboratory and their collaborators have discovered an aberrant protein that’s deadly to bacteria.

Tirzepatide Obesity Drug Shown to Reduce Body Weight by 20 Percent in Eli Lilly Trial

XTalks

Eli Lilly announced that its obesity drug tirzepatide has scored favorably in a late-stage clinical trial, with results showing that people who took the drug lost an average of 50 pounds, or 21 percent, of their body weight compared to placebo.