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World’s first engineered B cell therapy enters human trials

Drug Discovery World

The first patient has been dosed with an engineered B cell investigational therapy in a Phase I trial in Mucopolysaccharidosis type I (MPS I). Immusoft is advancing the world’s first engineered B cell therapy, which may have significant impact for patients with this rare disease and potentially many others.

Engineer 113
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Genetically engineered dendritic cells enhance lung cancer therapy

Drug Discovery World

A study by researchers at the UCLA Health Jonsson Comprehensive Cancer Center in the US suggests that injecting engineered dendritic cells directly into cancerous lung tumours can help promote a stronger immune response. Additionally, they observed that this therapy helped to establish a long-lasting immune response against the cancer.

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Actio, a precision medicine startup, launches with $55M and a mouse lab partnership

Bio Pharma Dive

The two-year-old San Diego biotech is allied with The Jackson Laboratory to engineer better mouse models of the rare diseases it plans to target.

Medicine 269
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A new paradigm for protein engineering 

Drug Discovery World

Adaptyv Bio, a Swiss/US technology company that develops infrastructure and tools for protein designers to engineer better proteins, has built a protein engineering foundry that it says will “pave the way” for protein designers to develop new medicines, novel enzymes and sustainable materials.

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Engineering A Healthier Future: The Power of Tissue Regeneration

Roots Analysis

The Art and Science of Tissue Engineering Do you know that scientists are now able to grow body parts in the lab? This incredible medical breakthrough is called tissue engineering. So, what is tissue engineering? Having said that regenerative grafts created using tissue engineering have numerous applications.

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CRISPR Pioneer Goes Small to Transform Genetic Medicine with Epigenetic Engineering

BioSpace

Epic Bio aims to transform genetic medicine by developing a new class of drugs that target the epigenome to alter gene expression.

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How to help the medicine go down: how UMass Amherst scientists are helping to engineer the next generation of medications

Scienmag

Researchers at the University of Massachusetts Amherst recently announced that they have engineered a new class of material, called a “polyzwitterionic complex,” or “pZC,” which is able to both withstand the harsh acidic conditions of the stomach and then dissolve predictably in the comparatively gentle environment of the small intestine.