pharmaphorum

NOVEMBER 29, 2023

Start-up Cradle tucks in $24m for protein engineering AI Phil.Taylor Wed, 29/11/2023 - 11:48 Bookmark this

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Engineer Protein 59

Scienmag

OCTOBER 7, 2021

Machine learning algorithms assist in protein engineering by reducing the experimental burden of methods such as directed evolution, which involves multiple rounds of mutagenesis and high-throughput screening. Credit: L.

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Engineer Protein 73

Drug Discovery World

DECEMBER 19, 2023

The first patient has been dosed with an engineered B cell investigational therapy in a Phase I trial in Mucopolysaccharidosis type I (MPS I). Immusoft is advancing the world’s first engineered B cell therapy, which may have significant impact for patients with this rare disease and potentially many others.

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Engineer Trials Genetic Disease Gene Therapy 113

Pharma Times

DECEMBER 20, 2023

Researchers from Johns Hopkins University School of Medicine have revealed new findings about a key pathological protein associated with Parkinson’s disease (PD), which could lead to new treatments. Estimated to affect over 8.5 However, its relation to dopaminergic neuron death is unclear.

Protein 93

Protein Medicine Engineer Genetics 93

Drug Discovery World

AUGUST 31, 2023

Evox Therapeutics, an exosome therapeutics company, has published Evox-funded research identifying novel exosome scaffold proteins that significantly improve drug loading into exosomes for therapeutic purposes in Nature Communications. Amongst the most potent are the novel tetraspanin scaffold proteins TSPAN2 and TSPAN3. “The

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Engineer Protein Gene Drugs 52

Scienmag

JANUARY 6, 2022

Protein assembly is essential for the formation of ordered biological structures, but imagine engineering one! This is exactly what researchers at Tokyo Tech have now accomplished with protein needles.

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Protein Engineer Regulation Research 79

BioTech 365

OCTOBER 11, 2021

FC (Fragment Crystallizable) Protein and Glyco-engineered Antibodies Market, 2030 – ResearchAndMarkets.com FC (Fragment Crystallizable) Protein and Glyco-engineered Antibodies Market, 2030 – ResearchAndMarkets.com DUBLIN–(BUSINESS WIRE)–The “Fc Protein and Glyco-engineered Antibodies Market: Focus on Type of Fc Engineering (..)

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Engineer Protein Antibody Marketing 40

Scienmag

NOVEMBER 17, 2021

Chemical topology is a unique dimension for protein engineering. Over the past few years, the discovery of topological nontrivial proteins in nature has already revealed their many potential functional benefits, such as enhanced thermal/mechanical/chemical stability.

Protein 80

Protein Antibody Engineer Development 80

BioTech 365

JANUARY 6, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: How engineered protein patches could boost immunotherapy.How engineered protein patches could boost immunotherapy aliu Wed, 01/06/2021 – 04:38 from FierceBiotech: Biotech [link].

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Engineer Protein Research 40

Scienmag

JANUARY 6, 2021

Proteins engineered to form honeycomb structures can block uptake of receptors from the surface of cells Credit: Ian Haydon, UW Medicine Institute for Protein Design A new class of protein material that interacts with living cells without being absorbed by them can influence cell signaling, a new study shows.

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Protein Engineer Medicine 84

Drug Discovery World

JULY 24, 2023

The Defense Advanced Research Projects Agency (DARPA) has announced that Ginkgo Bioworks, which is building a platform for cell programming and biosecurity, has been awarded a four-year contract worth up to $18 million to reimagine how to manufacture complex therapeutic proteins.

Protein 52

Protein Manufacturing Gene Sequencing Production 52

Medical Xpress

DECEMBER 5, 2022

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

Protein 75

Protein Genetic Engineering Research Engineer 75

Drug Discovery World

FEBRUARY 14, 2024

Adding automation Recombinant protein vaccines, which are obtained by conventional genetic engineering, are based on the proteins of target pathogens that can activate our immune systems. In particular, we must work to accelerate recombinant protein vaccine development. WuXi Biologics, and WuXi Vaccines.

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Protein Vaccination Vaccine Manufacturing 59

Drug Discovery World

FEBRUARY 12, 2024

million grant to engineer microbial cell factories to produce membrane proteins which will support future drug screening and sustainable chemical production. The Engineering Biology Mission Award was given by UK Research and Innovation (UKRI). A team from Aston University and the University of Warwick has secured a £1.8 ($2.2)

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Research Drugs Engineer Protein 105

Drug Discovery World

MARCH 21, 2023

In a step forward for genetic engineering and synthetic biology, US researchers have modified E coli bacteria to be immune to infection by all natural viruses tested so far. Genetic engineering The findings build on earlier efforts by genetic engineers, which involved genetically reprogramming E.

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Engineer Genetic Engineering Scientist Bacteria 52

Drug Discovery World

OCTOBER 26, 2022

An international team of scientists have engineered protein banana lectin, or BanLec, to create a new version that can fight off a range of viruses without unwanted side effects. . But it’s also exciting to have created it by engineering a lectin molecule for the first time, by understanding and then targeting the structure.” .

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Engineer Genetic Engineering Scientist Protein 52

Drug Discovery World

MARCH 30, 2023

Salipro Biotech, in collaboration with AstraZeneca, has published data from a study which describes a novel method to directly extract membrane proteins from cells into lipid Salipro nanoparticles, enabling structure-function analysis using surface plasmon resonance (SPR) and cryo-electron microscopy (cryo-EM) for challenging drug targets.

Protein 52

Protein Engineer Drugs Scientist 52

The Pharma Data

MAY 19, 2023

HIGH SCHOOL SCIENTISTS AND ENGINEERS WIN NEARLY $9 MILLION AT THE REGENERON INTERNATIONAL SCIENCE AND ENGINEERING FAIR 2023 Regeneron Pharmaceuticals, Inc. ” Regeneron ISEF provides a global stage for the best and brightest young scientists and engineers around the world.

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Engineer Scientist Protein Research 52

XTalks

MARCH 31, 2023

By growing high quality crystal structures of protein-based therapeutics under microgravity, researchers can gain better insights into their complex structures and stability. The proteins will be analyzed back on Earth using techniques such as X-ray diffraction and compared with crystals from the same biologics grown on Earth.

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Protein Research Development Manufacturing 97

Scienmag

JULY 7, 2022

Balancing how much protein you eat with the amount your body needs could reduce nitrogen releases to aquatic systems in the U.S. Credit: Courtesy Maya Almaraz Balancing how much protein you eat with […]. by 12% and overall nitrogen losses to air and water by 4%, according to a study from the University of California, Davis.

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Protein Engineer 85

BioTech 365

OCTOBER 8, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Deep-learning algorithm aims to accelerate protein engineering.Proteins are the molecular machines of all living cells and have been exploited for use in many applications, including therapeutics and … Continue reading → (..)

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Protein Engineer Research 40

Scienmag

JULY 15, 2021

New artificial intelligence software can compute protein structures in 10 minutes Credit: Ian Haydon, UW Medicine Institute for Protein Design Scientists have waited months for access to highly accurate protein structure prediction since DeepMind presented remarkable progress in this area at the 2020 Critical Assessment of Structure Prediction, or (..)

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Protein Scientist Medicine Engineer 98

BioPharma Reporter

NOVEMBER 23, 2023

Cradle, the biotech startup using generative AI to help scientists design and engineer proteins, has raised $24 million in Series A funding.

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Engineer Protein Scientist Regulation 104

Scienmag

FEBRUARY 14, 2022

Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.

Protein 87

Protein Research Engineer 87

Drug Discovery World

DECEMBER 12, 2022

The development of synthetic biology has provided a solution to engineer custom microbes into cell factories that can produce a product with improved properties. The post Partnership hopes to accelerate protein discovery and target identification appeared first on Drug Discovery World (DDW).

Protein 52

Protein Life Science Engineer Development 52

Drug Discovery World

FEBRUARY 23, 2023

Proteins are the basic building blocks and engines of biology. For decades, drug discovery and development have been constrained by limits in our knowledge of the relationship between protein sequence, structure and function, and the methods available to explore novel drug targets.

Protein 52

Protein Life Science Bioassay Development 52

Scienmag

MARCH 10, 2022

Close interactions with infectious disease set both University of California, Santa Cruz graduate student Ana Nuñez Castrejon and Associate Professor of Biomolecular Engineering Rebecca DuBois on the path of studying Respiratory syncytial virus (RSV), a common and sometimes dangerous respiratory disease for which there is not currently a vaccine.

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Immune Response Vaccination Vaccine Protein 77

Drug Discovery World

OCTOBER 26, 2022

A new method to study the proteins released by cells, which could lead to new biomarkers for diseases including cancer, has been developed by scientists at the Francis Crick Institute and Imperial College London. . Identifying the proteins . The new method involves adding chemical tags to sugar molecules which are added to cells.

Protein 52

Protein Genetics Containment Research 52

Scienmag

NOVEMBER 9, 2021

Osaka, Japan – One degree (Celsius) can make a difference: a team of investigators led by Osaka University has demonstrated regulation of a critical protein complex that occurs only at physiological temperature. Credit: Hiroaki Kubota et al.

Protein 83

Protein Regulation Engineer 83

Scienmag

MARCH 30, 2022

Russian researchers and their international collaborators have developed a full-function bioelectronic photocell using one molecule of a fluorescent protein attached to a carbon nanotube. The […].

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Protein Genetics Development Research 69

Scienmag

MARCH 29, 2021

Credit: The Protein Society The Protein Society, the premier international society dedicated to supporting protein research, announces the winners of the 2021 Protein Society Awards, which will be conferred at the 35th Anniversary Symposium (virtual), July 7 – 14, 2021.

Protein 73

Protein Research Engineer 73

BioTech 365

JANUARY 27, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers reveal recipe for engineering ribosomes.Ribosomes are complex molecular machines in the cell that catalyze the production of proteins.

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Engineer Research Protein Production 40

BioPharma Reporter

OCTOBER 6, 2021

Absci Corp, a synthetic biology firm, is partnering with pharma company, EQRx, to jointly engineer and develop several clinical candidates across multiple therapeutic areas, including oncology and immunology.

Protein 102

Protein Pharma Companies Production Engineer 102

Scienmag

NOVEMBER 11, 2020

Credit: Masato Kanemaki Researchers can now more accurately and precisely target specific proteins in yeast, mammalian cells and mice to study how knocking down specific protein traits can influence physical manifestation in a cell or organism. The Japan-based team published their results on November 11th in Nature Communications.

Protein 98

Protein Genetics RNA Development 98

Drug Discovery World

APRIL 18, 2024

By building and iterating on RNA sequences through the CodonCracker software and the Nutcracker Manufacturing Unit, Nutcracker reported that its scientists engineered a group of molecules with attenuated PSMA and CD3 (cluster of differentiation 3) binding to mitigate on-target, off-tumour binding and target-independent T cell activation.

Engineer 52

Engineer Drugs RNA Scientist 52

Scienmag

JULY 12, 2021

The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced by every cell. Researchers at Baylor College of Medicine and Rice University have found a new way to do just that […].

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Gene Expression Engineer Gene Protein 63

Scienmag

JULY 20, 2021

Artificially designed, amyloid-silk hybrid protein developed in Zhang lab even outperforms some spider silks Credit: Washington University in St. Now engineers at Washington University in St. Louis have designed amyloid silk hybrid proteins and produced them in engineered […].

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Engineer Protein Development Research 98