Decoding Epigenetic Triggers: Unveiling the Mechanisms Driving Hepatocellular Carcinoma
Scienmag
JUNE 18, 2025
In hepatic malignancies, dysregulation of histone acetylation is especially prominent, with overexpressed histone deacetylases (HDACs) fostering chromatin condensation and gene silencing. This epigenetic silencing mechanism extends to tumor suppressors, further exacerbating oncogenic shift.
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