Pharmaceutical Technology

JULY 20, 2022

Furthermore, researchers found that one of the genes turned on by these BET proteins is ACE2, the same protein that the virus depends on to get into cells. In the latest study, Gladstone graduate student Irene Chen and the team found that the BET proteins switch on genes that block viruses, in SARS-CoV-2 infected cells.

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Protein Scientist Gene DNA 278

Bio Pharma Dive

MARCH 2, 2022

A federal patent board ruled Broad Institute scientists were first to a key gene editing advance, weakening the patent position of Intellia and CRISPR Therapeutics, which hold licenses through the University of California.

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Gene Editing Gene Licensing Licensing 200

BioPharma Reporter

MARCH 22, 2024

Claudia Zylberberg is a scientist and founder, board member and former CEO of Akron Biotech, a company that makes materials and technologies to support advanced therapy development. We spoke to her about her career, personal triumphs and candidacy for President of the International Society for Cell and Gene Therapy (ISCT),

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Gene Gene Therapy Scientist Development 98

Medical Xpress

MAY 15, 2023

Scientists at Université de Montréal, McGill University and its affiliated Montreal Children's Hospital have made a promising breakthrough in understanding the origins of mirror movement disorder, a rare inherited neurological disorder.

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Scientist Gene Genetics 98

Scienmag

OCTOBER 1, 2021

Promising news in the effort to develop drugs to treat obesity: University of Virginia scientists have identified 14 genes that can cause and three that can prevent weight gain. The findings pave the way for treatments to combat a health problem that affects more than 40% of American adults.

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Scientist Gene Development Drugs 77

Bio Pharma Dive

MAY 10, 2023

Sarepta has not provided “unambiguous evidence” its treatment can help patients, agency scientists wrote in documents released ahead of a crucial Friday advisory committee meeting.

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Gene Therapy Gene Scientist 299

Bio Pharma Dive

OCTOBER 11, 2023

Once the specialty of a few select drugmakers, CRISPR gene editing is now an essential technology for a growing group of biotechs, many led by former students of the field's pioneering scientists.

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Gene Editing Gene Scientist 355

Medical Xpress

MAY 4, 2023

Mutations of a gene called Foxp2 have been linked to a type of speech disorder called apraxia that makes it difficult to produce sequences of sound. A new study from MIT and National Yang Ming Chiao Tung University sheds light on how this gene controls the ability to produce speech.

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Scienmag

DECEMBER 23, 2020

Forward genetics pinpoints gene linked to ASD involving severe speech impairment and opens door to search for more mutations, future treatments Credit: Photo taken by Brian Coats for UT Southwestern Medical Center DALLAS – Dec.

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Medical Xpress

MAY 2, 2023

Scientists at UMass Chan Medical School have developed a technology to deliver gene therapy directly to lung tissue through intranasal administration, a development that could potentially create a new class of treatments for lung disease.

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Scientist Gene Therapy Gene Development 98

Pharmaceutical Technology

JULY 7, 2022

But scientists have struggled to find effective treatments for many of these diseases since the dawn of modern medicine. Recent years have seen a steadily growing number of approvals for cell and gene therapies, which has spurred on the community to continue innovating in this space. A new frontier in cancer research.

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Gene Therapy Gene Medicine Genetics 245

NPR Health - Shots

MARCH 6, 2023

The last time this summit convened in 2018, the world was shocked to hear a scientist had created the first gene-edited babies. He was condemned, but gene-editing has continued, with some success. Image credit: Anthony Wallace/AFP via Getty Images)

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Gene Editing Gene Scientist 133

Scienmag

NOVEMBER 25, 2020

Credit: Professor Jane Farrar and Dr Daniel Maloney, Trinity College Dublin Scientists from Trinity College Dublin have developed a new gene therapy approach that offers promise for one day treating an eye disease that leads to a progressive loss of vision and affects thousands of people across the globe.

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Gene Therapy Scientist Gene Development 87

Scienmag

JULY 11, 2022

SAN FRANCISCO, CA—Using new technologies to study thousands of genes simultaneously within immune cells, researchers at Gladstone Institutes, UC San Francisco (UCSF), and Stanford School of Medicine have created the most detailed map yet of how complex networks of genes function together.

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Gene Scientist Medicine Research 72

Scienmag

NOVEMBER 12, 2021

Scientists working with an experimental mouse model at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified the essential role of the gene GPR126 in the development of the placenta during pregnancy.

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Scientist Gene Development 68

Medical Xpress

APRIL 10, 2023

Mutations in our genes can lead to severe problems, like colon or liver cancer. Mutations in the same genes can lead to different subtypes of tumors in different people. Currently, scientists don't have a good way to produce such tumor subtypes for study in the lab. But cancer is very complex.

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Gene Scientist 98

Scienmag

JUNE 24, 2021

NIH scientists discover that bacteria may drive activity of many hallmark aging genes in flies Credit: Courtesy of the Giniger lab NIH/NINDS.

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Scientist Gene Bacteria Research 72

Medical Xpress

JANUARY 23, 2023

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart's biological age by 10 years. The breakthrough, published in Cardiovascular Research and led by scientists at the University of Bristol and the MultiMedica Group in Italy, offers a potential target for patients with heart failure.

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Gene Scientist Research Cardiology 145

Medical Xpress

FEBRUARY 22, 2023

In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer's disease-related genes, providing a potential mechanistic explanation for why Alzheimer's is sometimes more frequent among adults who experienced obesity in midlife.

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Gene Scientist Research 70

Scienmag

OCTOBER 13, 2021

LA JOLLA—(October 13, 2021) For the past fifteen years, cancer researchers have been using DNA sequencing technology to identify the gene mutations that cause the different forms of cancer.

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Scienmag

APRIL 16, 2021

– April 16, 2021 – Scientists at Sanford Burnham Prebys have identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes COVID-19. Credit: Dotted Yeti LA JOLLA, CALIF.

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Scienmag

MARCH 21, 2022

Wilmington, DE, (MARCH 21, 2022) – A new study from scientists at ChristianaCare’s Gene Editing Institute is advancing the safety and efficacy of using CRISPR gene editing in patient treatments by demonstrating how to identify and evaluate the broad-based biological impact of gene editing on targeted tissues, where the edits are designed to fully disable (..)

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Gene Editing Gene Scientist DNA 80

Scienmag

APRIL 8, 2021

Credit: UT Southwestern Medical Center DALLAS – April 8, 2021 – New research has uncovered a surprising role for so-called “jumping” genes that are a source of genetic mutations responsible for a number of human diseases.

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Scientist Gene Genetics Research 77

Scienmag

NOVEMBER 29, 2021

CHAPEL HILL, NC – Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that rare variants in the ANK2 gene, consistently found in individuals with autism spectrum disorder (ASD), can alter architecture and organization of neurons, potentially contributing to autism and neurodevelopmental (..)

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Medical Xpress

DECEMBER 7, 2022

New research published in the Annals of Clinical and Translational Neurology has identified three genes and their expressed proteins that may be involved in the pathogenesis of multiple sclerosis.

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Gene Scientist Protein Research 72

STAT News

FEBRUARY 22, 2023

Moderna is aiming to build a gene editing franchise powered by some of the same technologies used in its COVID-19 vaccines. Life Edit is the North Carolina subsidiary of ElevateBio, a cell and gene therapy manufacturing firm in Waltham. Continue to STAT+ to read the full story…

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Scienmag

OCTOBER 26, 2020

New genetic sensors, developed by scientists at University of Warwick and Keele University, could function as a lab test device and even as a live monitoring system inside living cells The innovative system can detect when a specific gene in a cell is active – instead of only detecting its presence The technology is based […].

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NPR Health - Shots

MARCH 8, 2023

The Third International Summit on Genome Editing concluded Monday with ethicists warning scientists to slow down efforts to use gene-editing to enhance the health of embryos. Image credit: Mark Schiefelbein/AP)

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Medical Xpress

NOVEMBER 16, 2022

Researchers at the National Institutes of Health have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD).

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Pharmaceutical Technology

DECEMBER 14, 2022

Merck and Synplogen have signed a non-binding Memorandum of Understanding (MoU) to expedite the development and manufacturing of viral vector-based gene therapy applications. The firms intend to merge their expertise to provide simplified viral vector gene therapy development, production and testing in Japan. By Cytiva Thematic.

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Gene Therapy Gene Development Manufacturing 130

Drug Discovery World

JANUARY 10, 2024

New understanding of a gene that is linked to some forms of dementia and other age-related diseases gives scientists fresh hope that action can be taken against these diseases long before the onset of symptoms. The post Organoid research sheds light on gene mutation linked to dementia appeared first on Drug Discovery World (DDW).

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Gene Research Gene Therapy Life Science 59

Scienmag

MARCH 5, 2021

Researchers develop tunable system that harnesses the spread of cargo carried by gene drives Credit: Gerard Terradas, UC San Diego Powerful new genetic engineering methods have given scientists the potential to revolutionize several sectors of global urgency.

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Gene Scientist Genetic Engineering Genetics 52

Medical Xpress

APRIL 23, 2023

A discovery about gene variants of an inflammation 'brake' brings scientists a step closer to personalised treatment for patients at risk of kidney disease and kidney failure.

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Gene Scientist 82

Scienmag

MARCH 31, 2022

Gene editing technology has been used to pinpoint new molecular targets for treating an aggressive form of leukemia in adults. November 24, 2021 Gene editing technology has been used to pinpoint new molecular targets for treating an aggressive form of leukemia in adults. Hokkaido University scientists have identified new […].

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Gene Editing Gene Scientist 95

Medical Xpress

MAY 4, 2023

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it. While the gene was discovered more than four decades ago, researchers have so far been unsuccessful at determining exactly how it works.

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Scientist Gene Genome Genomics 105

Scienmag

SEPTEMBER 16, 2020

Credit: David Jandzik New University of Colorado Boulder-led research finds that the traits that make vertebrates distinct from invertebrates were made possible by the emergence of a new set of genes 500 million years ago, documenting an important episode in evolution where new genes played a significant role in the evolution of novel traits in […]. (..)

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Gene Family Gene Scientist Research 93

Drug Discovery World

FEBRUARY 22, 2024

Mark Treherne will talk about advanced therapies and the development of RNA gene therapy for aggressive cancers which is being carried out at Spliceor. Doug Danison will discuss transitioning innovative science into commercial success in the areas of CGTs.

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Gene Therapy Gene RNA Scientist 52