BioTech 365

JULY 22, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: How promiscuous protein droplets regulate immune genes.Biochemists at Emory are achieving insights into how an important regulator of the immune system switches its function, based on its … Continue reading →

Regulation 40

Regulation Protein Gene Research 40

Medical Xpress

APRIL 21, 2023

A new publication released today in The EMBO Journal identified a key protein in the molecular mechanism triggering neurogenesis in the hippocampus. They found that tight regulation of Yap1 activity is essential as dysregulation can cause tissue disruption seen in the early stages of brain cancer.

Protein 102

Protein Production Regulation Research 102

Scienmag

DECEMBER 11, 2021

Studying fruit flies, they found that the Apterous (Ap) protein plays a crucial double role in retaining memories. Not only did it bind with the Chi cofactor to help maintain memories, but it also acted independently to regulate […].

Protein 88

Protein Regulation Research 88

Bio Pharma Dive

JULY 26, 2022

But an apparent effect on a protein of interest in ALS research has Biogen convinced the treatment will pass muster with regulators. Known as tofersen, the drug failed in the main study being used to support its approval.

Drugs 321

Drugs Protein Regulation Research 321

Medical Xpress

APRIL 27, 2023

Research led by Maynooth University and published today in the journal Science Signaling has found that the protein MYC is essential for MAIT cell growth, proliferation, metabolism and function. The latest findings are of critical importance to the study of MAIT cells and the development of metabolic disease such as obesity.

Regulation 130

Regulation Protein Development Research 130

Medical Xpress

APRIL 24, 2023

Iron is important for life, and iron deficiency impairs development, but whether the iron level regulates neural differentiation remains elusive. Iron-regulatory proteins (IRPs), including IRP1 and IRP2, are the major regulators of cellular iron homeostasis.

Regulation 52

Regulation Protein Development Research 52

Scienmag

MARCH 1, 2022

The molecular evolution of placental protein NRK and its function in regulating placental growth has finally been clarified by researchers from Tokyo Tech. They elucidated that eutherian NRK regulates placental development by a novel mechanism, modulating the CK2-PTEN-AKT pathway.

Protein 94

Protein Regulation Development Research 94

BioTech 365

JULY 23, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers discover that protein switches functions to regulate DNA replication.One protein. One mechanism of action. Two biologically opposite effects.

DNA 40

DNA Protein Regulation Research 40

BioTech 365

FEBRUARY 26, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Transporter protein regulates root gravitropism in Arabidopsis.In

Regulation 40

Regulation Protein Research 40

Scienmag

NOVEMBER 9, 2021

Osaka, Japan – One degree (Celsius) can make a difference: a team of investigators led by Osaka University has demonstrated regulation of a critical protein complex that occurs only at physiological temperature. Credit: Hiroaki Kubota et al.

Protein 83

Protein Regulation Engineer 83

Medical Xpress

JANUARY 20, 2023

This process is regulated by a family of signaling proteins called sirtuins. A recent study by researchers from Kumamoto University reveals the mechanism through which the protein sirtuin 7 suppresses thermogenesis in mice. Mammals convert the energy stored in adipose (fat) tissue into heat via a process known as thermogenesis.

Protein 73

Protein Production Regulation Research 73

Pharmaceutical Technology

JUNE 20, 2023

SKYCovione is a self-assembled nanoparticle vaccine and the 12th Covid-19 vaccine to receive a EUL from the regulator. Developed using pharmaceutical company GSK’s pandemic adjuvant, the vaccine targets the receptor-binding domain of the SARS-CoV-2 spike protein.

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Vaccination Vaccine Protein Clinical Trials 363

Scienmag

APRIL 11, 2022

Yale scientists uncover key regulator of body weight. Yale scientists have discovered that a protein known as augmentor-alpha regulates body weight in mice, an insight that could lead to new treatments for metabolic disorders. New Haven, Conn.

Regulation 78

Regulation Scientist Protein Research 78

Medical Xpress

DECEMBER 14, 2022

Professor Suh Byung-chang's research team of the Department of Brain Sciences, DGIST, announced on Wednesday, November 23 that they have identified the molecular mechanism for the activation of "voltage-dependent calcium channels," an important protein that regulates the secretion of neurotransmitters at nerve cell terminals.

Regulation 75

Regulation Protein Research 75

BioTech 365

SEPTEMBER 28, 2021

Researchers Discover Previously Unknown Role of BioAegis’ Therapeutic Gelsolin as Key Signaling Protein Vital for Regulating Immune Cell Inflammatory Response Researchers Discover Previously Unknown Role of BioAegis’ Therapeutic Gelsolin as Key Signaling Protein Vital for Regulating Immune Cell Inflammatory Response … Continue reading → (..)

Regulation 40

Regulation Protein Research 40

Drug Discovery World

SEPTEMBER 21, 2022

According to a study published in Cell Reports, the breast cancer cells regulate their own metastases by fuelling dissemination from the original tumour and determining routes to invade distant organs like the lungs. The microscopy studies revealed that these cells enter a dormant state after invading the lungs by secreting the protein TGF?2.

Regulation 52

Regulation Protein In-Vivo Scientist 52

Scienmag

NOVEMBER 13, 2020

The results provide an interesting example of co-evolution of a circRNA, and its host-encoded protein product, that regulate each other’s […].

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RNA Regulation Protein Production 93

Medical Xpress

JANUARY 6, 2023

Tauopathies such as Alzheimer's disease are a class of neurodegenerative disorders involving an accumulation of tau proteins, which eventually results in massive loss of brain cells. There is little consensus about the underlying causes and no effective treatments are available currently for these disorders.

Regulation 105

Regulation Protein 105

Scienmag

JANUARY 11, 2022

A group of researchers has found that at least some of it has to do with a particular protein in the part of the forebrain that regulates, among other things, decision-making and reward perception. It’s a commonly heard question after New Year’s: “Why do we drink the way we do?” Credit: Shimon Amir It’s a […].

Protein 79

Protein Research Regulation 79

BioTech 365

SEPTEMBER 21, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Regulator proteins or symphonies of genes: Statistical modeling points way toward unified theory for DNA folding.At more than 2 meters long, the human DNA molecule uses intricate … Continue reading →

DNA 40

DNA Regulation Protein Gene 40

BioTech 365

JULY 5, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: A specific protein complex from plant stem cells regulates their division and response to stress.A multidisciplinary research team, led by the CSIC biologist at CRAG, Ana I. … Continue reading →

Regulation 40

Regulation Protein Research 40

pharmaphorum

OCTOBER 2, 2020

European regulators have started a first ‘rolling review’ of a COVID-19 vaccine, which is being developed by AstraZeneca in collaboration with the University of Oxford. After vaccination, the surface spike protein is produced, priming the immune system to attack the SARS-CoV-2 virus if it later infects the body.

Regulation 105

Regulation Vaccination Vaccine Protein 105

Scienmag

MARCH 12, 2021

Credit: The Wistar Institute PHILADELPHIA — (March 12, 2021) — Scientists at The Wistar Institute identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome […].

RNA 92

RNA Protein Genome Genomics 92

XTalks

JULY 26, 2021

But several researchers and experts have brought to light some food safety concerns of plant-based meat, and why it must be treated differently than that of animal protein. Because of their near-neutral pH and high protein and moisture content, plant-based meats are susceptible to microbial growth. FDA Regulation.

Protein 98

Protein Contamination Allergies Bacteria 98

AuroBlog - Aurous Healthcare Clinical Trials blog

MAY 18, 2023

In particular, researchers noticed a reduction in the interleukin-1-beta (IL-1β) protein, which helps to regulate the body’s […] It seems the chemical compound can stop some of the damage done to the brain that’s usually associated with the disease.

Protein 198

Protein Regulation Research Clinical Trials 198

Drug Discovery World

MAY 18, 2023

Scientists in Japan have used a novel technique to identify a protein complex degraded by autophagy that has a possible role in liver cancer. p62 protein forms a membrane-less cytosolic organelle called p62 body and helps in the selective removal of toxic cellular waste through autophagy.

Protein 52

Protein Scientist Medicine Regulation 52

Scienmag

JULY 11, 2021

Johns Hopkins researchers describe protein regulating key step in cancer metastasis Credit: Johns Hopkins University Researchers have identified a specialized protein that appears to help prevent tumor cells from entering the bloodstream and spreading to other parts of the body.

Protein 69

Protein Regulation Research Engineer 69

Scienmag

FEBRUARY 11, 2021

Study reveals mechanism used to regulate chaperone proteins, which guide other proteins into proper shapes Credit: UT Southwestern Medical Center DALLAS – Feb. The […].

Protein 52

Protein Regulation Medicine 52

Scienmag

APRIL 22, 2021

Notch proteins are key regulators of growth and differentiation of both normal and cancer cells. Researchers in Turku, Finland, have now demonstrated that the activities of distinct Notch family members are modified differently by phosphorylation.

Hormones 75

Hormones Regulation Research Protein 75

BioSpace

JANUARY 10, 2021

Regulating the activity of the protein called NF-kappa B-inducing kinase (NIK) is emerging as a new and potentially important way to enhance certain immuno-oncology therapies.

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Regulation Protein 66

FDA Law Blog

MARCH 5, 2024

Gaulkin & Riëtte van Laack — As readers of this blog know, there is a lot of contention about the naming of alternative protein products (APPs), including both plant-based and cell-cultured alternatives for (traditional) animal products. By Sophia R. We’ve previously blogged about this ongoing battle here , here , here , and here.

Protein 59

Protein Production DNA Containment 59

Scienmag

AUGUST 28, 2020

Credit: OIST A protein that’s common throughout the body plays a key role in regulating glucose levels, says new research conducted in the Cell Signal Unit at the Okinawa Institute of Science and Technology Graduate University (OIST) and Riken Center of Integrative Medical Sciences.

Protein 52

Protein Regulation Research Gene 52

Medical Xpress

FEBRUARY 21, 2023

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

Immune Response 72

Immune Response Regulation Protein 72

BioSpace

SEPTEMBER 11, 2020

Can you imagine organizing more than 10 terabytes of data into a useful network of information, like creating Google maps from scratch? I certainly can’t, but Eclipse BioInnovations, a San Diego-based biotech start-up, is aiming to do just that for RNA therapeutics.

RNA 103

RNA Regulation Protein Gene 103

The Pharma Data

MARCH 7, 2022

By combining CRISPR technology with a protein designed with artificial intelligence (AI), it is possible to awaken individual dormant genes by disabling the chemical “off switches” that silence them. The chemical modifications that regulate gene activity are called epigenetic markers. it can be reawakened.

Protein 52

Protein Gene Genome Genomics 52

BioPharma Reporter

MARCH 27, 2023

The biotech is launched with an antibody-based protein degradation platform, with technology licensed from UCSF.

Protein 52

Protein Licensing Licensing Antibody 52

Scienmag

JANUARY 28, 2022

A protein that masterminds the way DNA is wrapped within chromosomes has a major role in the healthy functioning of blood stem cells, which produce all blood cells in the body, according to a new study from researchers at Weill Cornell Medicine. The protein, known as histone H3.3,

Regulation 57

Regulation DNA Research Development 57