Rethinking Clinical Trials

MARCH 28, 2024

Rosa Gonzalez-Guarda The NIH Pragmatic Trials Collaboratory’s Health Equity Core developed a written aid to offer guidance on inclusive language and terms to use when referring to specific people, groups, and communities. View the Equitable Language Cheat Sheet.

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Rethinking Clinical Trials

AUGUST 22, 2023

In an article published this month in Clinical Trials , researchers from the NIH Pragmatic Trials Collaboratory’s Distributed Research Network share opportunities for conducting pragmatic trials embedded in health insurance plans.

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Antidote

MARCH 12, 2024

For many people, participating in a research study presents an interesting opportunity with many benefits to volunteering. While there are many types of clinical research, all with distinct goals and timelines, trial volunteers will follow a similar path when taking part. Read on to learn more about the process.

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Worldwide Clinical Trials

JANUARY 24, 2024

Written By: Derek Ansel, MS, CCRA, Executive Director, Therapeutic Strategy Lead, Rare Disease Given that 80% of rare diseases have a genetic etiology, genetic implications should be addressed at the onset of a clinical program to support trial enrollment. One diagnostic example that I discussed in my presentation is autism.

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Rethinking Clinical Trials

JULY 12, 2023

Stephanie Morain At the NIH Pragmatic Trials Collaboratory Steering Committee’s annual meeting in May, Dr. Stephanie Morain discussed the results of a recent bioethics initiative to explore ethical considerations for data sharing in the context of pragmatic clinical trials.

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Bio Pharma Dive

NOVEMBER 13, 2023

Explore how decentralized clinical trials (DCTs) can enhance rare disease research in three key ways.

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Worldwide Clinical Trials

APRIL 3, 2024

Are you aware of the challenges you must address for a successful radiopharmaceutical trial? Enhancing Patient Participation in Radiopharmaceutical Trials Patient recruitment is a critical yet challenging part of radiopharmaceutical trials.

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Rethinking Clinical Trials

APRIL 23, 2024

In the new secondary analysis from the TSOS study, the research team examined relationships between patients' clinical and demographic characteristics and rates of follow-up in the study. Learn more about the NIH Collaboratory Trials.

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Pharmaceutical Technology

JANUARY 3, 2024

A new report from Novotech delves into the multifaceted landscape of HIV, focusing on its impact, treatment, and global initiatives.

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Antidote

JANUARY 18, 2024

Antidote’s mission is to connect patients with medical research so medical breakthroughs can take place. We provide our clinical trial matching technology, Antidote Match, at no cost to these organizations, to help patients and caregivers discover new research opportunities and connect to clinical trials quickly and easily.

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AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 10, 2022

More evidence of the link has arrived with a phase 2, double-blind trial involving 233 participants, the largest study on this subject carried out so far in terms of sample size. For some years now, scientists have been investigating how psilocybin, the psychedelic compound in magic mushrooms, can ease the symptoms of depression.

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Rethinking Clinical Trials

MARCH 5, 2024

The NIH Pragmatic Trials Collaboratory will offer a preconference workshop at the 45th Annual Meeting of the Society for Clinical Trials in Boston. Firsthand experiences with embedded pragmatic clinical trials and case studies from the NIH Pragmatic Trials Collaboratory will support and illustrate the topics presented.

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Bio Pharma Dive

NOVEMBER 3, 2021

Data readouts for Pfizer's hemophilia gene therapies are now expected later than previously forecast, while the company also works through modifying a trial of its Duchenne treatment.

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Rethinking Clinical Trials

FEBRUARY 23, 2023

February 20, 2023 : The NIH Pragmatic Trials Collaboratory hosted a Pre-Conference Workshop, “Changing Trials for Changing Times: Essentials of Embedded Pragmatic Clinical Trials Workshop,” at the Health Care Systems Research Network 2023 Annual Conference.

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Worldwide Clinical Trials

FEBRUARY 28, 2023

Rob found out that in 1980, a researcher in Birmingham, England first synthesized a very niche cancer drug in a small lab. Over the next few decades, that drug made its way through clinical trials, securing approval in 2007—just 36 months before Rob was diagnosed in 2010. But what was truly remarkable? But what was truly remarkable?

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Rethinking Clinical Trials

JULY 18, 2023

Lynn DeBar and Dr. Natalia Morone In an interview at the annual NIH Pragmatic Trials Collaboratory Steering Committee meeting, Dr. Lynn DeBar and Dr. Natalia Morone had a conversation about sharing trial results with participant partners. Stakeholder perspectives may also change over time, so research teams should be flexible.

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ProRelix Research

MAY 31, 2023

Introduction: Clinical trials are a crucial component of the pharmaceutical and medical research industry, aimed at evaluating the safety and effectiveness of new drugs, treatments, or medical devices before they […] The post Successful Clinical Trial With ProRelix Research: Phase 1, 2, 3 & 4 Clinical Trial Services at … appeared (..)

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Rethinking Clinical Trials

APRIL 18, 2024

During the course of the years-long pragmatic clinical trials supported by the NIH Pragmatic Trials Collaboratory, many unanticipated challenges have occurred, some of which have had profound effects on usual care, trial implementation, data systems, and staff. Section 4 : COVID-19 had significant impacts on trial activities.

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Rethinking Clinical Trials

JULY 5, 2023

June 23-24, 2023 : The NIH Pragmatic Trials Collaboratory hosted a Pre-Conference Workshop, “Changing Trials for Changing Times: Essentials of Embedded Pragmatic Clinical Trials Workshop,” at the Health Care Systems Research Network 2023 Annual Conference.

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Worldwide Clinical Trials

MARCH 20, 2024

One way to ensure customized disease management is to utilize pharmacogenomics (PGx) in your clinical trial. As the study of how an individual’s genes affect their response to drugs, pharmacogenomics is a critical factor in developing effective and safe drugs and dosages in clinical trials.

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Rethinking Clinical Trials

MARCH 27, 2024

Amit Garg and Stephanie Dixon In this Friday’s PCT Grand Rounds, Amit Garg and Stephanie Dixon of Western University’s Schulich School of Medicine and Dentistry will present “Effect of a Multicomponent Intervention to Improve Patient Access to Kidney Transplant and Living Kidney Donation: A Pragmatic, Cluster-Randomized Trial.”

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Rethinking Clinical Trials

APRIL 24, 2023

Russell Rothman and Erin Holve as they discuss a decade of research in PCORnet®. The post Podcast April 14, 2023: From Observational Studies to Pragmatic Clinical Trials: Research in PCORnet® appeared first on Rethinking Clinical Trials. Click on the recording below to listen to the podcast. Read the transcript.

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Rethinking Clinical Trials

JANUARY 22, 2024

What happens to a pragmatic trial intervention after the study ends? Based on the experiences of the 6 case studies, the authors offer several recommendations to assist pragmatic trials researchers in considering the posttrial sustainment or de-implementation of their study interventions. Read the full article.

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Rethinking Clinical Trials

JANUARY 11, 2024

In a new article from the NIH Pragmatic Trials Collaboratory, the BeatPain Utah study team describes the "implementation mapping" they used to plan for trial implementation. The post January 11, 2024: BeatPain Utah Study Team Uses Implementation Mapping Approach to Plan Hybrid Trial appeared first on Rethinking Clinical Trials.

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Antidote

APRIL 16, 2024

Effectively recruiting patients for clinical trials is one of the most integral parts of conducting research, and difficulties in the process are often responsible for delays.

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Bio Pharma Dive

JUNE 12, 2023

Decentralized clinical trials (DCTs) bring many benefits to the clinical research process, and more importantly, the patients. However, it is important to remember the risks if there is no data security process in place.

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Rethinking Clinical Trials

OCTOBER 9, 2023

The NIH Pragmatic Trials Collaboratory will offer a full-day workshop at the 16th Annual Conference on the Science of Dissemination and Implementation in Health in Arlington, Virginia. ” The annual conference is cohosted by the NIH and AcademyHealth. ” The annual conference is cohosted by the NIH and AcademyHealth.

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Rethinking Clinical Trials

DECEMBER 13, 2023

In this Friday's PCT Grand Rounds, Roxana Mehran of the Icahn School of Medicine at Mount Sinai will present "Diversifying Clinical Trials: A Path Forward." Mehran is a professor of medicine and the director of interventional cardiovascular research and clinical trials at the Zena and Michael A. Join the online meeting.

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AuroBlog - Aurous Healthcare Clinical Trials blog

FEBRUARY 20, 2024

The Indian Institute of Science (IISc) and Blockchain For Impact (BFI) have teamed up to maximise translational research projects where the latter aims to allocate US$1 million. The collaboration, under the BFI-Biome Virtual Network Programme, will see BFI to support various research projects at the IISc.

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Pharmaceutical Technology

FEBRUARY 13, 2024

Research indicates that designing clinical trials with the patient in mind reduces recruitment times and enhances trial performance.

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Rethinking Clinical Trials

DECEMBER 18, 2023

December 10, 2023 : The NIH Pragmatic Trials Collaboratory hosted a Workshop at the 2023 AcademyHealth 16th Annual Conference on the Science of Dissemination and Implementation in Health.

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Rethinking Clinical Trials

OCTOBER 31, 2023

The study is administered by the National Institute of Nursing Research and will be conducted by Diana Burgess of the Minneapolis Veterans Affairs Healthcare System, Roni Evans of the University of Minnesota, and Katherine Hadlandsmyth of the University of Iowa.

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Antidote

SEPTEMBER 26, 2023

Recruiting patients for a clinical trial can be a challenging process. Studies show that many patients report having little or no knowledge of clinical trials , and sponsors and researchers often report having difficulties finding and enrolling patients in studies.

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AuroBlog - Aurous Healthcare Clinical Trials blog

MARCH 6, 2024

Oncologists during clinical trials of paediatric cancer cases are seen to encounter parent reluctance. Since the trials involve a lot of government permissions as well and many healthcare facilities, hospitals under NDA […]

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