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CAPTIVATE Study Shows an IMBRUVICA® (ibrutinib) Plus VENCLEXTA®/VENCLYXTO® (venetoclax) Chemotherapy-Free Combination Has Potential to Provide Remission After Fixed-Duration Treatment for Chronic Lymphocytic Leukemia (CLL)

The Pharma Data

Patients received 3 cycles of ibrutinib lead-in followed by 12 cycles of ibrutinib + venetoclax (Ibr 420 mg/day PO; Ven ramp up to 400 mg/day PO). NORTH CHICAGO, Ill. NORTH CHICAGO, Ill. months of follow up. This rate was higher than the 37% minimum meaningful rate study assumption (P<0.0001).

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IMBRUVICA® (ibrutinib) Plus VENCLEXTA®/VENCLYXTO® (venetoclax) Combination Shows Superior Progression-Free Survival Compared to Chlorambucil Plus Obinutuzumab in First-line Chronic Lymphocytic Leukemia (CLL) Phase 3 GLOW Study

The Pharma Data

Results of the study will be presented at the European Hematology Association (EHA) 2021 Virtual Congress ( Abstract #LB1902 ) during late-breaking abstract session on June 12 from 4:00-5:30 p.m. I+V is the first all-oral, once-daily, chemotherapy-free, fixed-duration investigational combination.