Antibody - Clinical Research Informer

Almirall licenses IL-21 antibody from Novo Nordisk

Pharmaceutical Technology

FEBRUARY 19, 2024

Almirall has signed a licensing agreement for the acquisition of worldwide rights to Novo Nordisk’s IL21-hindering antibody NN-8828.

Licensing

Licensing Licensing Antibody

J&J antibody drug combination shows promise in multiple myeloma

Bio Pharma Dive

MAY 25, 2023

A pair of dual-acting antibodies displayed early potential to become a new type of drug regimen for the blood cancer, but led to a high rate of side effects as well.

Antibody

Antibody Drugs

Yuhan gets grant for patent granted for anti-PD-L1 IGG class antibodies

Pharmaceutical Technology

APRIL 23, 2024

Discover how Yuhan Corp's patent for anti-PD-L1 IgG class antibodies revolutionizes manufacturing yields. Learn about the advancements in production efficiency and potential therapeutic applications.

Antibody

Antibody Manufacturing Production

Xencor gets grant for bispecific antibody for treating GPC3-associated cancers

Pharmaceutical Technology

APRIL 4, 2024

Discover Xencor Inc's groundbreaking patent for novel GPC3 binding domains and bispecific antibodies targeting GPC3-associated cancers. Explore the innovative method for manufacturing these antibodies and their potential in cancer treatment.

Antibody

Antibody Manufacturing

UCB gets grant for dual-specific IL-17a and IL-17F antibody for therapy

Pharmaceutical Technology

APRIL 23, 2024

UCB SA patent for IL-17A and IL-17F antibody molecules with expression vectors and host cell methods. Discover the innovative approach to efficient nucleic acid expression.

Antibody

AbCellera Biologics gets grant for enhanced production of diverse antibodies using genetically modified mice

Pharmaceutical Technology

APRIL 22, 2024

Discover a broader repertoire of antibodies with a recently granted patent. Enhance immunoglobulin diversity with AbCellera's patented method for isolating B cells from genetically modified mice.

Genetics

Genetics Antibody Production

Vir Biotechnology gets grant for multispecific antibodies for zika virus infection treatment

Pharmaceutical Technology

APRIL 18, 2024

Discover how Vir Biotechnology's patented multispecific antibodies target distinct Zika virus epitopes, neutralizing ZIKV infection. Explore the innovative potential for prophylaxis and treatment in this groundbreaking patent.

Antibody

Gilead and Merus enter trispecific antibody discovery deal

Pharmaceutical Technology

MARCH 7, 2024

Gilead Sciences has entered an agreement with Merus for the discovery of dual tumour-associated antigens targeting trispecific antibodies.

Antibody

OSE Immunotherapeutics gets grant for humanized monoclonal antibodies targeting CD127 for therapeutic and diagnostic use

Pharmaceutical Technology

APRIL 22, 2024

Discover the groundbreaking patent by OSE Immunotherapeutics SA for humanized monoclonal antibodies targeting CD127, offering innovative solutions for inhibiting inflammation and treating autoimmune, allergic, and viral diseases.

Antibody

Bristol-Myers Squibb gets grant for humanized antibodies binding CD40 for treatment of CD40-related diseases

Pharmaceutical Technology

APRIL 23, 2024

Learn about modified antibodies and potential treatments in this groundbreaking publication. Discover Bristol-Myers Squibb's innovative patent for a pharmaceutical composition targeting human CD40 activity.

Antibody

Talem and Libera Bio partner for discovery of AI-driven antibodies

Pharmaceutical Technology

MARCH 16, 2023

Talem Therapeutics, a subsidiary of Immunoprecise Antibodies, has entered a multi-target artificial intelligence (AI)-driven antibody discovery collaboration with Libera Bio. The MPN Technology provides an elegant way for delivering antibodies inside tumour cells.

Antibody

Antibody In-Vivo Pharma Companies Protein

Japan grants patent for BioArctic’s Parkinson’s disease antibody

Pharmaceutical Technology

AUGUST 24, 2023

Japan has granted a new drug substance patent for BioArctic’s monoclonal antibody (mAb), BAN0805, to treat Parkinson’s disease.

Antibody

Antibody Drugs

Kyowa Kirin gets grant for monoclonal antibody inhibiting ccr1 activation by ccl15

Pharmaceutical Technology

APRIL 10, 2024

Discover the groundbreaking patent by Kyowa Kirin Co Ltd for a monoclonal antibody targeting CCR1, inhibiting its activation by CCL15. Explore the therapeutic and diagnostic potential for CCR1-related diseases.

Antibody

Genzyme gets grant for method for reducing interference in drug assay due to antibodies

Pharmaceutical Technology

APRIL 15, 2024

Discover Genzyme Corp's innovative method for detecting anti-drug antibodies in human body fluids. Learn how their patented process reduces interference in drug assays effectively.

Antibody

Antibody Drugs

Basilea wins CARB-X grant for new antibody development

Pharmaceutical Technology

APRIL 9, 2024

The grant will support the preclinical development of the antibody acquired by Basilea from Spexis in January.

Antibody

Antibody Development

Cue Biopharma gets grant for fusion polypeptide with variant IL-2 and antibody fc region

Pharmaceutical Technology

APRIL 18, 2024

Explore the innovative fusion polypeptide with IL-2 and antibody Fc region, revolutionizing T cell activity modulation. Discover Cue Biopharma's groundbreaking patent for variant immunomodulatory polypeptides and fusion polypeptides, including T-cell modulatory multimeric polypeptides.

Antibody

Innovation in immuno-oncology: Leading companies in cancer monoclonal antibody therapy

Pharmaceutical Technology

FEBRUARY 15, 2023

In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Immuno-oncology: Leading companies in cancer monoclonal antibody therapy. Immatics is one of the most important players concerning innovation surrounding cancer monoclonal antibody therapy.

Antibody

Antibody Immune Response Protein Development

AACR, Cancer Treatment and the Promise of Antibody-Drug Conjugates

BioSpace

APRIL 12, 2024

This week’s American Association for Cancer Research annual meeting drove home the importance of antibody-drug conjugates as an emerging class of potential anti-cancer therapeutics.

Antibody

Antibody Drugs Research

AVEO Pharmaceuticals gets grant for decreasing blood urea nitrogen levels in hyperuricemia using anti-gdf15 antibody

Pharmaceutical Technology

APRIL 15, 2024

Discover a groundbreaking method to treat renal disorders with AVEO Pharmaceuticals Inc's patented anti-GDF15 antibody. Learn how this innovative approach targets hyperuricemia and CKD for improved renal function.

Antibody

OSE Immunotherapeutics gets grant for anti-human SIRPA antibody for treating cancer

Pharmaceutical Technology

MARCH 28, 2024

Revolutionize cancer treatment with OSE Immunotherapeutics' patented anti-SIRPa antibodies targeting human SIRPa for enhanced T cell response and antigen presentation. Discover a comprehensive approach to treating various cancers with innovative combination therapies.

Antibody

UCB gets grant for treatment of systemic lupus erythematosus with anti-CD154 antibody

Pharmaceutical Technology

APRIL 1, 2024

Treat systemic lupus erythematosus effectively with UCB SA's patented method using a specific antibody to CD154. Significant improvements in SLE indices and outcomes. Explore the potential of this innovative treatment now!

Antibody

AbbVie announces acquisition of DJS Antibodies for $255m

Pharmaceutical Technology

OCTOBER 21, 2022

AbbVie has announced the acquisition of UK-based biotechnology firm DJS Antibodies for nearly $255m in cash at closing. DJS focuses on the discovery and development of antibody therapies that act on difficult-to-drug disease-causing proteins, such as G protein-coupled receptors (GPCRs).

Antibody

Antibody Protein Licensing Licensing

Pfizer files patent for multi-drug antibody drug conjugates with site-specific construction

Pharmaceutical Technology

MARCH 26, 2024

Discover Pfizer's innovative patent for multi-drug Antibody Drug Conjugates and Linking Assembly Units, enabling precise and effective drug delivery. Explore the cutting-edge technology behind site-specific construction and versatile drug linking options.

Antibody

Antibody Drug Delivery Drugs

Immune-Onc’s antibody therapy collects second FDA orphan designation

Pharmaceutical Technology

FEBRUARY 22, 2024

The company’s monoclonal antibody therapy, IO-202, has received its second orphan drug designation as a treatment for a blood cancer, CMML.

Antibody

Antibody Drugs

Genmab files patent for treatment of diffuse large B-cell lymphoma using bispecific antibody

Pharmaceutical Technology

MARCH 26, 2024

Discover Genmab AS's innovative patent for treating DLBCL with a bispecific antibody and R-CHOP regimen. Learn about specific dosages and administration schedules for improved patient outcomes.

Antibody

AstraZeneca to deliver Covid-19 antibody therapy doses to Switzerland

Pharmaceutical Technology

JULY 21, 2022

AstraZeneca has signed a deal with the Federal Office of Public Health (FOPH) of Switzerland to deliver over 1,200 doses of antibody therapy, tixagevimab and cilgavimab combination (AZD7442), for Covid-19 prevention and treatment. In June 2020, these antibodies, discovered at Vanderbilt University Medical Center, were licensed to AstraZeneca.

Antibody

Antibody Compliance Clinical Trials Clinical Trials

Ono and EVQLV partner to develop new antibody drugs

Pharmaceutical Technology

DECEMBER 22, 2023

Ono has signed an agreement with EVQLV to utilise its AI-powered antibody design engine for the development of new antibody drugs.

Antibody

Antibody Development Engineer Drugs

Ono Pharmaceutical partners with EME for antibody drug discovery

Pharmaceutical Technology

FEBRUARY 22, 2024

Ono Pharmaceutical has partnered with EME to advance the drug discovery of VHH antibodies to develop new therapeutic agents.

Antibody

Antibody Drugs Development

US FDA approves Eisai-Biogen’s antibody for Alzheimer’s

Pharmaceutical Technology

JANUARY 9, 2023

Eisai and Biogen have received approval for their antibody Leqembi (lecanemab-irmb) , 100mg/mL injection for intravenous use, from the US Food and Drug Administration (FDA) under the Accelerated Approval Pathway to treat Alzheimer’s disease (AD). The regulatory approval is based on the data obtained from the Phase II trial.

FDA Approval

FDA Approval Antibody Clinical Trials Clinical Trials

Atrium Health gets grant for cancer treatment using antibodies and engineered cytotoxic cells

Pharmaceutical Technology

APRIL 15, 2024

Discover how Atrium Health's groundbreaking patent revolutionizes cancer treatment with targeted antibodies and cytotoxic cells, enhancing immune response and improving patient outcomes.

Antibody

Antibody Immune Response Engineer

Leading innovators in anti-influenza antibody compositions for the pharmaceutical industry

Pharmaceutical Technology

MAY 8, 2023

In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Anti-influenza antibody compositions. However, not all innovations are equal and nor do they follow a constant upward trend.

Antibody

Antibody Vaccination Vaccine Dermatology

Webinar: How can we develop better therapeutic antibodies?

Drug Discovery World

APRIL 22, 2024

Join DDW for this free event ‘ Where is the opportunity in the therapeutic antibody market? ’, which is co-sponsored by Bio-Rad and Benchling. Dr Milind Nigam will discuss the role of software in accelerating the pace of discovery of antibody therapeutics. What effect has antibody engineering had on drug discovery and development?

Antibody

Antibody Development Gene Therapy Marketing

FDA turns down Regeneron bispecific blood cancer antibody

pharmaphorum

MARCH 25, 2024

FDA has turned down a pair of marketing applications for Regeneron’s CD20xCD3 bispecific antibody odronextamab to treat two common forms of non-Hodgkin lymphoma

Antibody

Antibody Marketing

BioAtla gets grant for method of preparing conditionally active antibodies or antibody fragments

Pharmaceutical Technology

DECEMBER 22, 2023

Discover a groundbreaking method for preparing conditionally active antibodies. This recently granted patent covers evolving DNA to increase acidic amino acid residues, selecting mutants, and assessing activity under specific conditions. Explore the potential of this innovative approach.

Antibody

Antibody DNA

Boehringer to leverage IBM’s technologies for antibody discovery

Pharmaceutical Technology

NOVEMBER 28, 2023

Boehringer Ingelheim has entered an agreement with IBM to leverage the latter’s foundation model technologies for antibody discovery.

Antibody

Nona Biosciences and ModeX Therapeutics partner for antibodies discovery

Pharmaceutical Technology

MAY 24, 2023

HBM’s wholly owned subsidiary Nona Biosciences has entered an agreement with OPKO Health’s ModeX Therapeutics for the discovery of antibodies. ModeX Therapeutics will gain access to the fully human Harbour Mice platforms of Nona Bioscience for integration into its MSTAR platform to expedite the monoclonal antibodies’ discovery.

Antibody

Antibody Clinical Development Development Research

Daiichi Sankyo and AstraZeneca’s lung cancer antibody set for FDA review

Pharmaceutical Technology

FEBRUARY 19, 2024

An FDA approval in late 2024 would make it the first TROP2-directed therapy for NSCLC antibody drug conjugate patients.

Antibody

Antibody FDA Approval Drugs

Newly launched Calluna raises $81m to advance monoclonal antibody pipeline

Pharmaceutical Technology

JANUARY 23, 2024

Calluna has four monoclonal antibody candidates in the pipeline under development for inflammatory and fibrotic diseases.

Antibody

Antibody Development

Nona Biosciences and Evive enter antibody discovery deal

Pharmaceutical Technology

DECEMBER 11, 2023

Nona Biosciences has entered a partnership deal with biopharmaceutical company Evive Biotech to discover antibodies.

Antibody

AbCellera and Regeneron expand antibody discovery collaboration

Pharmaceutical Technology

SEPTEMBER 21, 2023

AbCellera and Regeneron have extended their current multi-target collaboration to discover therapeutic antibodies for up to eight targets

Antibody

Signal: Absci and AstraZeneca sign deal on AI-powered cancer antibody drug

Pharmaceutical Technology

DECEMBER 4, 2023

The $247m deal will focus on the use of generative artificial intelligence to develop an antibody therapy for an unnamed cancer.

Antibody

Antibody Drugs Development

China’s NMPA approves ArkBio’s RSV neutralising antibody drug

Pharmaceutical Technology

NOVEMBER 24, 2023

China’s NMPA has approved ArkBio IND application for its respiratory syncytial virus (RSV) neutralising antibody, AK0610.

Antibody

Antibody Drugs

Drugmakers take sides in Amgen, Regeneron fight over antibody patents

Bio Pharma Dive

APRIL 21, 2023

A decision by the Supreme Court could have far-reaching effects on the lucrative market for antibody drugs, spurring responses from many of the industry’s top companies.

Antibody

Antibody Marketing Drugs

Almirall and EpimAb partner to develop bispecific antibody therapies

Pharmaceutical Technology

OCTOBER 12, 2023

Almirall will license EpimAb’s Fabs-In-Tandem Immunoglobulin (FIT-Ig) platform to develop up to three bispecific antibody targets.

Antibody

Antibody Development Licensing Licensing

Almirall licenses IL-21 antibody from Novo Nordisk

J&J antibody drug combination shows promise in multiple myeloma

Trending Sources

Yuhan gets grant for patent granted for anti-PD-L1 IGG class antibodies

Xencor gets grant for bispecific antibody for treating GPC3-associated cancers

UCB gets grant for dual-specific IL-17a and IL-17F antibody for therapy

AbCellera Biologics gets grant for enhanced production of diverse antibodies using genetically modified mice

Vir Biotechnology gets grant for multispecific antibodies for zika virus infection treatment

Gilead and Merus enter trispecific antibody discovery deal

OSE Immunotherapeutics gets grant for humanized monoclonal antibodies targeting CD127 for therapeutic and diagnostic use

Bristol-Myers Squibb gets grant for humanized antibodies binding CD40 for treatment of CD40-related diseases

Talem and Libera Bio partner for discovery of AI-driven antibodies

Japan grants patent for BioArctic’s Parkinson’s disease antibody

Kyowa Kirin gets grant for monoclonal antibody inhibiting ccr1 activation by ccl15

Genzyme gets grant for method for reducing interference in drug assay due to antibodies

Basilea wins CARB-X grant for new antibody development

Cue Biopharma gets grant for fusion polypeptide with variant IL-2 and antibody fc region

Innovation in immuno-oncology: Leading companies in cancer monoclonal antibody therapy

AACR, Cancer Treatment and the Promise of Antibody-Drug Conjugates

AVEO Pharmaceuticals gets grant for decreasing blood urea nitrogen levels in hyperuricemia using anti-gdf15 antibody

OSE Immunotherapeutics gets grant for anti-human SIRPA antibody for treating cancer

UCB gets grant for treatment of systemic lupus erythematosus with anti-CD154 antibody

AbbVie announces acquisition of DJS Antibodies for $255m

Pfizer files patent for multi-drug antibody drug conjugates with site-specific construction

Immune-Onc’s antibody therapy collects second FDA orphan designation

Genmab files patent for treatment of diffuse large B-cell lymphoma using bispecific antibody

AstraZeneca to deliver Covid-19 antibody therapy doses to Switzerland

Ono and EVQLV partner to develop new antibody drugs

Ono Pharmaceutical partners with EME for antibody drug discovery

US FDA approves Eisai-Biogen’s antibody for Alzheimer’s

Atrium Health gets grant for cancer treatment using antibodies and engineered cytotoxic cells

Leading innovators in anti-influenza antibody compositions for the pharmaceutical industry

Webinar: How can we develop better therapeutic antibodies?

FDA turns down Regeneron bispecific blood cancer antibody

BioAtla gets grant for method of preparing conditionally active antibodies or antibody fragments

Boehringer to leverage IBM’s technologies for antibody discovery

Nona Biosciences and ModeX Therapeutics partner for antibodies discovery

Daiichi Sankyo and AstraZeneca’s lung cancer antibody set for FDA review

Newly launched Calluna raises $81m to advance monoclonal antibody pipeline

Nona Biosciences and Evive enter antibody discovery deal

AbCellera and Regeneron expand antibody discovery collaboration

Signal: Absci and AstraZeneca sign deal on AI-powered cancer antibody drug

China’s NMPA approves ArkBio’s RSV neutralising antibody drug

Drugmakers take sides in Amgen, Regeneron fight over antibody patents

Almirall and EpimAb partner to develop bispecific antibody therapies

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