Spotlighting Lupus Awareness Month: CAR-T Technology Creates New Avenues for Treatment of a Devastating Disease
WCG Clinical
MAY 28, 2024
An expected and well-known side effect of these B cell-targeted therapies is “B cell aplasia”— i.e. partial or complete depletion of B cells from circulation and immune organs. Lymphocytes have an extraordinary capacity to proliferate in response to immune stimulation. In these cases B cell depletion is a feature, not a bug.
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