Drug Discovery World

NOVEMBER 17, 2022

It is believed that the term synthetic biology was created in 1970 by geneticist, Waclaw Szybalski 1 as work was being carried out on the development of DNA sequencing and synthesis techniques. The Rockefeller University 2 recently reported the development of a synthetic antibiotic that could potentially work against drug-resistant bacteria.

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The Pharma Data

JANUARY 4, 2021

But scientists at the University of California (UC), Santa Barbara, believe fluoride may offer hope in the fight against antibiotic-resistant bacteria. ” This method may also provide significant cost-savings, particularly in relation to antibiotic-driven selection in research laboratories. ” Source link.

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Drug Discovery World

FEBRUARY 6, 2024

The company has created a novel AI platform to develop enzymes from bacteria-killing viruses (bacteriophages) as a new way to tackle bacterial infections, and has secured €4 million investment to support its development. In June 2023, lab automation company Opentrons launched its Flex robots for scientists using generative AI.

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Drug Discovery World

OCTOBER 11, 2023

Dr Luke Clifton , Instrument Scientist at ISIS Neutron and Muon Source, explains the molecular mechanism behind antibiotics. The two main classes of bacteria are separated based on their differing cell surface architecture. The two main classes of bacteria are separated based on their differing cell surface architecture.

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XTalks

DECEMBER 24, 2020

After being identified in December 2019 in Wuhan, Hubei in China, medical officials and scientists got to work to isolate and identify the novel virus that they observed to be causing a new respiratory illness. The system can be used to precisely edit out portions of DNA flanked by CRISPR sequences.

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Drug Discovery World

MAY 2, 2023

Steve Wowk , VP, Business Unit and General Management of Integrated DNA Technologies, shared with DDW the value of CRISPR-Cas9 in drug discovery. In an effort to defend themselves against viral infection, bacterial cells capture and copy DNA fragments of bacteriophages into their genome. Some cells die while others thrive.

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Drug Discovery World

APRIL 30, 2024

Proteins perform myriad functions within the human body and scientists have estimated that there are at least 20,000 canonical proteins that we know about. For example, mRNA testing can offer deeper insights compared to DNA and give researchers a better understanding of gene expression in relation to certain cancers.

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Drug Discovery World

AUGUST 10, 2022

The immune system typically identifies foreign entities such as bacteria and viruses and activates lymphocytes such as T cells to destroy them with overwhelming force. To overcome the challenge of identifying the ideal target, scientists are using several creative methods. The challenge of manufacturing CAR T cells.

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Drug Discovery World

JULY 18, 2023

Rolf Turk , Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. parvovirus B19, Flaviviridae, Ebola, and Coronaviridae), DNA viruses (e.g., Herpesviridae, Polyomaviridae, and Papillomaviridae), bacteria (e.g.,

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DNA Genome Genomics RNA 98

Drug Discovery World

APRIL 25, 2024

For instance, bacteria and yeast cell lines are easier to cultivate compared with mammalian cell lines, requiring less maintenance for the medium they are grown in. HEK 293 cells on the other hand are used within viral vector productions which have wide-scale applications for vaccines and therapies. Bacterial cell lines such as E.

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pharmaphorum

SEPTEMBER 14, 2020

The human genome is too long to be sequenced as one continuous string by current technology – so short-read sequencing breaks DNA into short fragments that are amplified and then sequenced to produce ‘reads’ of around 150 nucleotides in length. To address these issues, scientists and clinicians are starting to look at ‘long-read’ sequencing.

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The Pharma Data

JANUARY 21, 2021

The test valuates mitochondrial DNA levels. When mitochondrial DNA, normally found inside cells, in the mitochondria, spills into the bloodstream, it signals that a particular type of violent cell death is occurring. They measured the patients’ mitochondrial DNA levels on the first day of their hospital stays.

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XTalks

AUGUST 2, 2023

2) Botox Therapeutic/Cosmetic Botox, or botulinum neurotoxin, is a neurotoxic protein produced by the Clostridium botulinum bacteria. 5) Lynparza (Olaparib) Lynparza is a PARP inhibitor , meaning it inhibits poly ADP ribose polymerase (PARP), an enzyme involved in DNA repair. AbbVie’s total global revenue for Humira was $21.24

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